Marcus Bantscheff

Marcus Bantscheff

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Marcus Bantscheff

Marcus Bantscheff

Publications by authors named "Marcus Bantscheff"

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Nonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins.

Mol Cell Proteomics 2019 12 3;18(12):2506-2515. Epub 2019 Oct 3.

European Molecular Biology Laboratory (EMBL) Heidelberg, Meyerhofstraβe 1, 69117 Heidelberg, Germany

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http://dx.doi.org/10.1074/mcp.TIR119.001481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885700PMC
December 2019

Advanced proteomics approaches to unravel protein homeostasis.

Drug Discov Today Technol 2019 Apr 23;31:99-108. Epub 2019 Feb 23.

Cellzome GmbH, GlaxoSmithKline, Meyerhofstrasse 1, 69117 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ddtec.2019.02.001DOI Listing
April 2019

PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding.

ACS Chem Biol 2019 03 27;14(3):342-347. Epub 2019 Feb 27.

GSK Medicines Research Centre , Gunnels Wood Road , Stevenage SG1 2NY , U.K.

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http://dx.doi.org/10.1021/acschembio.8b01094DOI Listing
March 2019

Monitoring Dynamic Changes of the Cell Surface Glycoproteome by Quantitative Proteomics.

Methods Mol Biol 2017 ;1647:47-59

Cellzome, A GSK Company, Meyerhofstrasse 1, 69117, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7201-2_3DOI Listing
April 2018

Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition.

J Am Chem Soc 2018 01 9;140(3):932-939. Epub 2018 Jan 9.

Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.

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http://dx.doi.org/10.1021/jacs.7b08979DOI Listing
January 2018

Differential Kinobeads Profiling for Target Identification of Irreversible Kinase Inhibitors.

ACS Chem Biol 2017 10 12;12(10):2515-2521. Epub 2017 Sep 12.

Cellzome GmbH, GlaxoSmithKline , Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://pubs.acs.org/doi/10.1021/acschembio.7b00617
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http://dx.doi.org/10.1021/acschembio.7b00617DOI Listing
October 2017

Wilhelm et al. reply.

Nature 2017 07;547(7664):E23

Chair of Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer Forum 5, 85354 Freising, Germany.

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http://dx.doi.org/10.1038/nature22294DOI Listing
July 2017

Monitoring Cell-surface -Glycoproteome Dynamics by Quantitative Proteomics Reveals Mechanistic Insights into Macrophage Differentiation.

Mol Cell Proteomics 2017 05 23;16(5):770-785. Epub 2017 Mar 23.

From ‡Cellzome, A GSK Company, Meyerhofstrasse 1, 69117 Heidelberg, Germany

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http://dx.doi.org/10.1074/mcp.M116.063859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417820PMC
May 2017

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition.

Nat Commun 2016 11 4;7:13312. Epub 2016 Nov 4.

Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.

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http://dx.doi.org/10.1038/ncomms13312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097156PMC
November 2016

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level.

ACS Chem Biol 2016 09 20;11(9):2541-50. Epub 2016 Jul 20.

Cellzome GmbH, a GlaxoSmithKline Company , Meyerhofstrasse 1, D- 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1021/acschembio.6b00346DOI Listing
September 2016

Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle.

ACS Chem Biol 2016 Feb 7;11(2):518-29. Epub 2016 Jan 7.

Muscle Metabolism Discovery Performance Unit, GlaxoSmithKline , Research Triangle Park, North Carolina 27709, United States.

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http://dx.doi.org/10.1021/acschembio.5b00772DOI Listing
February 2016

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.

Nat Methods 2015 Dec 2;12(12):1129-31. Epub 2015 Nov 2.

Cellzome GmbH, Molecular Discovery Research, GlaxoSmithKline, Heidelberg, Germany.

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http://dx.doi.org/10.1038/nmeth.3652DOI Listing
December 2015

A Scalable Approach for Protein False Discovery Rate Estimation in Large Proteomic Data Sets.

Mol Cell Proteomics 2015 Sep 17;14(9):2394-404. Epub 2015 May 17.

From the ‡Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany;

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http://dx.doi.org/10.1074/mcp.M114.046995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563723PMC
September 2015

Catalytic in vivo protein knockdown by small-molecule PROTACs.

Nat Chem Biol 2015 Aug 10;11(8):611-7. Epub 2015 Jun 10.

1] Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA. [2] Department of Chemistry, Yale University, New Haven, Connecticut, USA. [3] Department of Pharmacology, Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nchembio.1858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629852PMC
August 2015

Mapping protein complexes using covalently linked antibodies and isobaric mass tags.

Methods Mol Biol 2014 ;1156:279-91

Cellzome GmbH, Meyerhofstrasse 1, 69117, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0685-7_19DOI Listing
December 2014

Quantifying small molecule-induced changes in cellular protein expression and posttranslational modifications using isobaric mass tags.

Methods Mol Biol 2014 ;1156:431-43

Cellzome GmbH, Meyerhofstrasse 1, 69117, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0685-7_29DOI Listing
December 2014

Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics.

Mol Cell Proteomics 2014 Dec 8;13(12):3709-15. Epub 2014 Aug 8.

From the ‡Chair for Proteomics and Bioanalytics, Center of Life and Food Sciences Weihenstephan, Technische Universität München, Freising, Germany; ‖Center for Integrated Protein Science Munich, Germany

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http://dx.doi.org/10.1074/mcp.M114.041038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256517PMC
December 2014

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes.

ACS Chem Biol 2014 Aug 6;9(8):1736-46. Epub 2014 Jun 6.

Cellzome GmbH, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1021/cb500235nDOI Listing
August 2014

Ion coalescence of neutron encoded TMT 10-plex reporter ions.

Anal Chem 2014 Apr 11;86(7):3594-601. Epub 2014 Mar 11.

Cellzome GmbH , Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://pubs.acs.org/doi/10.1021/ac500140s
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http://dx.doi.org/10.1021/ac500140sDOI Listing
April 2014

Measuring and managing ratio compression for accurate iTRAQ/TMT quantification.

J Proteome Res 2013 Aug 2;12(8):3586-98. Epub 2013 Jul 2.

Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1021/pr400098rDOI Listing
August 2013

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

ACS Chem Biol 2013 Mar 7;8(3):599-607. Epub 2013 Jan 7.

Cellzome GmbH, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://pubs.acs.org/doi/10.1021/cb3005879
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http://dx.doi.org/10.1021/cb3005879DOI Listing
March 2013

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

ACS Chem Biol 2012 Nov 23;7(11):1858-65. Epub 2012 Aug 23.

Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, U.K.

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http://dx.doi.org/10.1021/cb300326zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621575PMC
November 2012

Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present.

Anal Bioanal Chem 2012 Sep 8;404(4):939-65. Epub 2012 Jul 8.

Cellzome AG, Meyerhofstrasse 1, 69117, Heidelberg, Germany.

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http://link.springer.com/10.1007/s00216-012-6203-4
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http://dx.doi.org/10.1007/s00216-012-6203-4DOI Listing
September 2012

Quantitative mass spectrometry in proteomics.

Anal Bioanal Chem 2012 Sep;404(4):937-8

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http://link.springer.com/10.1007/s00216-012-6261-7
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http://dx.doi.org/10.1007/s00216-012-6261-7DOI Listing
September 2012

Mass spectrometry approaches to monitor protein-drug interactions.

Methods 2012 Aug 8;57(4):430-40. Epub 2012 Jun 8.

Cellzome AG, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ymeth.2012.05.008DOI Listing
August 2012

High-resolution enabled TMT 8-plexing.

Anal Chem 2012 Aug 8;84(16):7188-94. Epub 2012 Aug 8.

Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1021/ac301553xDOI Listing
August 2012

Mass spectrometry-based chemoproteomic approaches.

Methods Mol Biol 2012 ;803:3-13

Cellzome AG, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-61779-364-6_1DOI Listing
March 2012

Chemoproteomic approaches to drug target identification and drug profiling.

Bioorg Med Chem 2012 Mar 9;20(6):1973-8. Epub 2011 Nov 9.

Cellzome AG, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.bmc.2011.11.003DOI Listing
March 2012

Mass spectrometry-based proteomics in preclinical drug discovery.

Chem Biol 2012 Jan;19(1):72-84

Novartis Institutes for BioMedical Research, Inc., Cambridge, MA 02139, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10745521120001
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http://dx.doi.org/10.1016/j.chembiol.2012.01.002DOI Listing
January 2012

Evaluation of data analysis strategies for improved mass spectrometry-based phosphoproteomics.

Anal Chem 2010 Dec 29;82(23):9843-9. Epub 2010 Oct 29.

Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1021/ac102083qDOI Listing
December 2010

H-score, a mass accuracy driven rescoring approach for improved peptide identification in modification rich samples.

J Proteome Res 2010 Nov 21;9(11):5511-6. Epub 2010 Sep 21.

Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1021/pr1006813DOI Listing
November 2010

Targeted data acquisition for improved reproducibility and robustness of proteomic mass spectrometry assays.

J Am Soc Mass Spectrom 2010 Oct 25;21(10):1668-79. Epub 2010 Jan 25.

Department of Analytical Sciences, Cellzome AG, Heidelberg, Germany.

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http://link.springer.com/10.1016/j.jasms.2010.01.012
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http://dx.doi.org/10.1016/j.jasms.2010.01.012DOI Listing
October 2010

Revealing promiscuous drug-target interactions by chemical proteomics.

Drug Discov Today 2009 Nov 23;14(21-22):1021-9. Epub 2009 Jul 23.

Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.drudis.2009.07.001DOI Listing
November 2009

Chemical and pathway proteomics: powerful tools for oncology drug discovery and personalized health care.

Mol Cell Proteomics 2008 Oct 1;7(10):1887-901. Epub 2008 Aug 1.

Deptartment of Discovery Technology, Cellzome AG, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1074/mcp.R800006-MCP200DOI Listing
October 2008

Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer.

Mol Cell Proteomics 2008 Sep 29;7(9):1702-13. Epub 2008 May 29.

Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1074/mcp.M800029-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556025PMC
September 2008

Human Proteinpedia enables sharing of human protein data.

Authors:
Suresh Mathivanan Mukhtar Ahmed Natalie G Ahn Hainard Alexandre Ramars Amanchy Philip C Andrews Joel S Bader Brian M Balgley Marcus Bantscheff Keiryn L Bennett Erik Björling Blagoy Blagoev Ron Bose Samir K Brahmachari Alma S Burlingame Xosé R Bustelo Gerard Cagney Greg T Cantin Helene L Cardasis Julio E Celis Raghothama Chaerkady Feixia Chu Philip A Cole Catherine E Costello Robert J Cotter David Crockett James P DeLany Angelo M De Marzo Leroi V DeSouza Eric W Deutsch Eric Dransfield Gerard Drewes Arnaud Droit Michael J Dunn Kojo Elenitoba-Johnson Rob M Ewing Jennifer Van Eyk Vitor Faca Jayson Falkner Xiangming Fang Catherine Fenselau Daniel Figeys Pierre Gagné Cecilia Gelfi Kris Gevaert Jeffrey M Gimble Florian Gnad Renu Goel Pavel Gromov Samir M Hanash William S Hancock H C Harsha Gerald Hart Faith Hays Fuchu He Prashantha Hebbar Kenny Helsens Heiko Hermeking Winston Hide Karin Hjernø Denis F Hochstrasser Oliver Hofmann David M Horn Ralph H Hruban Nieves Ibarrola Peter James Ole N Jensen Pia Hønnerup Jensen Peter Jung Kumaran Kandasamy Indu Kheterpal Reiko F Kikuno Ulrike Korf Roman Körner Bernhard Kuster Min-Seok Kwon Hyoung-Joo Lee Young-Jin Lee Michael Lefevre Minna Lehvaslaiho Pierre Lescuyer Fredrik Levander Megan S Lim Christian Löbke Joseph A Loo Matthias Mann Lennart Martens Juan Martinez-Heredia Mark McComb James McRedmond Alexander Mehrle Rajasree Menon Christine A Miller Harald Mischak S Sujatha Mohan Riaz Mohmood Henrik Molina Michael F Moran James D Morgan Robert Moritz Martine Morzel David C Muddiman Anuradha Nalli J Daniel Navarro Thomas A Neubert Osamu Ohara Rafael Oliva Gilbert S Omenn Masaaki Oyama Young-Ki Paik Kyla Pennington Rainer Pepperkok Balamurugan Periaswamy Emanuel F Petricoin Guy G Poirier T S Keshava Prasad Samuel O Purvine B Abdul Rahiman Prasanna Ramachandran Y L Ramachandra Robert H Rice Jens Rick Ragna H Ronnholm Johanna Salonen Jean-Charles Sanchez Thierry Sayd Beerelli Seshi Kripa Shankari Shi Jun Sheng Vivekananda Shetty K Shivakumar Richard J Simpson Ravi Sirdeshmukh K W Michael Siu Jeffrey C Smith Richard D Smith David J States Sumio Sugano Matthew Sullivan Giulio Superti-Furga Maarit Takatalo Visith Thongboonkerd Jonathan C Trinidad Mathias Uhlen Joël Vandekerckhove Julian Vasilescu Timothy D Veenstra José-Manuel Vidal-Taboada Mauno Vihinen Robin Wait Xiaoyue Wang Stefan Wiemann Billy Wu Tao Xu John R Yates Jun Zhong Ming Zhou Yunping Zhu Petra Zurbig Akhilesh Pandey

Nat Biotechnol 2008 Feb;26(2):164-7

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http://dx.doi.org/10.1038/nbt0208-164DOI Listing
February 2008

Pathway proteomics and chemical proteomics team up in drug discovery.

Neurodegener Dis 2007 ;4(2-3):270-80

Cellzome AG, Department of Discovery Research, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000101851DOI Listing
October 2007

Quantitative mass spectrometry in proteomics: a critical review.

Anal Bioanal Chem 2007 Oct 1;389(4):1017-31. Epub 2007 Aug 1.

Cellzome AG, Meyerhofstrasse 1, 69254, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00216-007-1486-6DOI Listing
October 2007

Femtomol sensitivity post-digest (18)O labeling for relative quantification of differential protein complex composition.

Rapid Commun Mass Spectrom 2004 ;18(8):869-76

Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1002/rcm.1418DOI Listing
May 2004

Proteome analysis of diseased joints from mice suffering from collagen-induced arthritis.

Clin Chem Lab Med 2003 Dec;41(12):1622-32

Institute of Immunology, Medical Faculty, University of Rostock, Rostock, Germany.

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http://dx.doi.org/10.1515/CCLM.2003.246DOI Listing
December 2003