Publications by authors named "Marco Tripodi"

94 Publications

Design and Functional Validation of a Mutant Variant of the LncRNA to Counteract Snail Function in Epithelial-to-Mesenchymal Transition.

Authors:
Cecilia Battistelli Sabrina Garbo Veronica Riccioni Claudia Montaldo Laura Santangelo Andrea Vandelli Raffaele Strippoli Gian Gaetano Tartaglia Marco Tripodi Carla Cicchini

Cancer Res 2021 Jan 6;81(1):103-113. Epub 2020 Nov 6.

Department of Molecular Medicine, Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.

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January 2021

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis.

Authors:
Raffaele Strippoli Pilar Sandoval Roberto Moreno-Vicente Lucia Rossi Cecilia Battistelli Michela Terri Lucía Pascual-Antón Marta Loureiro Francesca Matteini Enrique Calvo José Antonio Jiménez-Heffernan Manuel José Gómez Victor Jiménez-Jiménez Fátima Sánchez-Cabo Jesús Vázquez Marco Tripodi Manuel López-Cabrera Miguel Ángel Del Pozo

Cell Death Dis 2020 08 3;11(8):647. Epub 2020 Aug 3.

Mechanoadaptation & Caveolae Biology Lab, Cell and Developmental Biology Area, Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029, Madrid, Spain.

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August 2020

Hypoxia-Induced miR-675-5p Supports β-Catenin Nuclear Localization by Regulating GSK3-β  Activity in Colorectal Cancer Cell Lines.

Authors:
Laura Saieva Maria Magdalena Barreca Chiara Zichittella Maria Giulia Prado Marco Tripodi Riccardo Alessandro Alice Conigliaro

Int J Mol Sci 2020 May 28;21(11). Epub 2020 May 28.

Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, 90133 Palermo, Italy.

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May 2020

Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.

Authors:
Annalisa Romanelli Giulia Stazi Rossella Fioravanti Clemens Zwergel Elisabetta Di Bello Silvia Pomella Clara Perrone Cecilia Battistelli Raffaele Strippoli Marco Tripodi Donatella Del Bufalo Rossella Rota Daniela Trisciuoglio Antonello Mai Sergio Valente

ACS Med Chem Lett 2020 May 19;11(5):977-983. Epub 2020 Mar 19.

Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185 Rome, Italy.

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May 2020

Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation.

Authors:
Clemens Zwergel Rossella Fioravanti Giulia Stazi Federica Sarno Cecilia Battistelli Annalisa Romanelli Angela Nebbioso Eduarda Mendes Alexandra Paulo Raffaele Strippoli Marco Tripodi Dany Pechalrieu Paola B Arimondo Teresa De Luca Donatella Del Bufalo Daniela Trisciuoglio Lucia Altucci Sergio Valente Antonello Mai

Cancers (Basel) 2020 Feb 14;12(2). Epub 2020 Feb 14.

Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185 Rome, Italy.

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February 2020

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation.

Authors:
Valeria Noce Cecilia Battistelli Angela Maria Cozzolino Veronica Consalvi Carla Cicchini Raffaele Strippoli Marco Tripodi Alessandra Marchetti Laura Amicone

Cell Death Dis 2019 10 10;10(10):768. Epub 2019 Oct 10.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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October 2019

Goal-Oriented Behaviour: The Ventral Tegmental Area in Motivated Movements.

Authors:
Laura Masullo Marco Tripodi

Curr Biol 2019 10;29(19):R922-R925

Neurobiology Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. Electronic address:

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October 2019

TGFβ Impairs HNF1α Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases.

Authors:
Francesca Bisceglia Cecilia Battistelli Valeria Noce Claudia Montaldo Agatino Zammataro Raffaele Strippoli Marco Tripodi Laura Amicone Alessandra Marchetti

Front Pharmacol 2019 30;10:942. Epub 2019 Aug 30.

Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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August 2019

Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus.

Authors:
Laura Masullo Letizia Mariotti Nicolas Alexandre Paula Freire-Pritchett Jerome Boulanger Marco Tripodi

Curr Biol 2019 09 29;29(17):2892-2904.e8. Epub 2019 Aug 29.

MRC Laboratory of Molecular Biology, Neurobiology Division, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address:

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September 2019

Éloge de la Fuite: Neural Circuits for Avoiding Dangerous Situations.

Authors:
Ana González-Rueda Marco Tripodi

Trends Neurosci 2019 10 6;42(10):657-659. Epub 2019 Aug 6.

Neurobiology Division, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK. Electronic address:

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October 2019

Looking at Synaptic Specificity from a Different Angle.

Authors:
Letizia Mariotti Marco Tripodi

Neuron 2019 06;102(6):1091-1093

MRC Laboratory of Molecular Biology, Cambridge, UK. Electronic address:

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June 2019

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.

Authors:
Clemens Zwergel Michael Schnekenburger Federica Sarno Cecilia Battistelli Maria Cristina Manara Giulia Stazi Roberta Mazzone Rossella Fioravanti Christina Gros Frédéric Ausseil Cristina Florean Angela Nebbioso Raffaele Strippoli Toshikazu Ushijima Katia Scotlandi Marco Tripodi Paola B Arimondo Lucia Altucci Marc Diederich Antonello Mai Sergio Valente

Clin Epigenetics 2019 05 6;11(1):68. Epub 2019 May 6.

Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.

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May 2019

Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output.

Authors:
Stefano L Giandomenico Susanna B Mierau George M Gibbons Lea M D Wenger Laura Masullo Timothy Sit Magdalena Sutcliffe Jerome Boulanger Marco Tripodi Emmanuel Derivery Ole Paulsen András Lakatos Madeline A Lancaster

Nat Neurosci 2019 04 18;22(4):669-679. Epub 2019 Mar 18.

MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK.

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April 2019

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.

Authors:
Giulia Stazi Cecilia Battistelli Valentina Piano Roberta Mazzone Biagina Marrocco Sara Marchese Sharon M Louie Clemens Zwergel Lorenzo Antonini Alexandros Patsilinakos Rino Ragno Monica Viviano Gianluca Sbardella Alessia Ciogli Giancarlo Fabrizi Roberto Cirilli Raffaele Strippoli Alessandra Marchetti Marco Tripodi Daniel K Nomura Andrea Mattevi Antonello Mai Sergio Valente

Eur J Med Chem 2019 Feb 28;163:722-735. Epub 2018 Nov 28.

Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy. Electronic address:

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February 2019

The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation.

Authors:
Cecilia Battistelli Giovanna Sabarese Laura Santangelo Claudia Montaldo Frank J Gonzalez Marco Tripodi Carla Cicchini

Cell Death Differ 2019 05 28;26(5):890-901. Epub 2018 Aug 28.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Cellular Biotechnologies and Haematology, Sapienza University of Rome, Rome, Italy.

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May 2019

Negative Regulation of Mitochondrial Antiviral Signaling Protein-Mediated Antiviral Signaling by the Mitochondrial Protein LRPPRC During Hepatitis C Virus Infection.

Authors:
Giulia Refolo Fabiola Ciccosanti Martina Di Rienzo Ariel Basulto Perdomo Marta Romani Tonino Alonzi Marco Tripodi Giuseppe Ippolito Mauro Piacentini Gian Maria Fimia

Hepatology 2019 01 18;69(1):34-50. Epub 2018 Dec 18.

National Institute for Infectious Diseases IRCCS 'L. Spallanzani', Rome, Italy.

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January 2019

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal.

Authors:
Lucia Rossi Cecilia Battistelli Valeria de Turris Valeria Noce Clemens Zwergel Sergio Valente Alessandra Moioli Andrea Manzione Marco Palladino Veronica Bordoni Alessandro Domenici Paolo Menè Antonello Mai Marco Tripodi Raffaele Strippoli

Sci Rep 2018 05 31;8(1):8492. Epub 2018 May 31.

Department of Cellular Biotechnologies and Hematology, Section of Molecular Genetics, Sapienza University of Rome, Rome, Italy.

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May 2018

Three-Dimensional Representation of Motor Space in the Mouse Superior Colliculus.

Authors:
Jonathan J Wilson Nicolas Alexandre Caterina Trentin Marco Tripodi

Curr Biol 2018 06 17;28(11):1744-1755.e12. Epub 2018 May 17.

MRC Laboratory of Molecular Biology, Cambridge, UK. Electronic address:

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June 2018

A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.

Authors:
Fruzsina Hobor Andre Dallmann Neil J Ball Carla Cicchini Cecilia Battistelli Roksana W Ogrodowicz Evangelos Christodoulou Stephen R Martin Alfredo Castello Marco Tripodi Ian A Taylor Andres Ramos

Nat Commun 2018 02 26;9(1):831. Epub 2018 Feb 26.

Research Department of Structural and Molecular Biology, University College London, Darwin Building, Gower Street, London, WC1E 6XA, UK.

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February 2018

SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer.

Authors:
Paolo Magistri Cecilia Battistelli Raffaele Strippoli Niccolò Petrucciani Teijo Pellinen Lucia Rossi Livia Mangogna Paolo Aurello Francesco D'Angelo Marco Tripodi Giovanni Ramacciato Giuseppe Nigri

Front Pharmacol 2017 2;8:956. Epub 2018 Feb 2.

Department of Medical and Surgical Sciences and Translational Medicine, Sapienza-University of Rome, Rome, Italy.

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February 2018

Hepatitis C virus direct-acting antivirals therapy impacts on extracellular vesicles microRNAs content and on their immunomodulating properties.

Authors:
Laura Santangelo Veronica Bordoni Claudia Montaldo Eleonora Cimini Alessandra Zingoni Cecilia Battistelli Gianpiero D'Offizi Maria R Capobianchi Angela Santoni Marco Tripodi Chiara Agrati

Liver Int 2018 10 24;38(10):1741-1750. Epub 2018 Feb 24.

Laboratory of Cellular Immunology and Pharmacology, National Institute for Infectious Diseases "Lazzaro Spallanzani" I.R.C.C.S., Rome, Italy.

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October 2018

Labeling and identifying cell-specific proteomes in the mouse brain.

Authors:
Toke P Krogager Russell J Ernst Thomas S Elliott Laura Calo Václav Beránek Ernesto Ciabatti Maria Grazia Spillantini Marco Tripodi Michael H Hastings Jason W Chin

Nat Biotechnol 2018 02 18;36(2):156-159. Epub 2017 Dec 18.

Medical Research Council Laboratory of Molecular Biology, Cambridge, England, UK.

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February 2018

Targeting of polycombs to DNA in EMT.

Authors:
Cecilia Battistelli Marco Tripodi Carla Cicchini

Oncotarget 2017 Aug 12;8(35):57936-57937. Epub 2017 Aug 12.

Department of Cellular Biotechnologies and Haematology, Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.

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August 2017

Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes.

Authors:
Carmine Mancone Alessio Grimaldi Giulia Refolo Isabella Abbate Gabriella Rozera Dario Benelli Gian Maria Fimia Vincenzo Barnaba Marco Tripodi Mauro Piacentini Fabiola Ciccosanti

Proteome Sci 2017 4;15:18. Epub 2017 Aug 4.

Department of Epidemiology, Preclinical Research and Advanced Diagnostics, National Institute for Infectious Diseases L. Spallanzani, IRCCS, via Portuense 292, 00149 Rome, Italy.

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August 2017

Life-Long Genetic and Functional Access to Neural Circuits Using Self-Inactivating Rabies Virus.

Authors:
Ernesto Ciabatti Ana González-Rueda Letizia Mariotti Fabio Morgese Marco Tripodi

Cell 2017 Jul 6;170(2):382-392.e14. Epub 2017 Jul 6.

Division of Neurobiology, MRC Laboratory of Molecular Biology, Cambridge, UK. Electronic address:

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July 2017

Nonenzymatic Oligomerization of 3',5'-Cyclic CMP Induced by Proton and UV Irradiation Hints at a Nonfastidious Origin of RNA.

Authors:
Giovanna Costanzo Alessandra Giorgi Anita Scipioni Anna Maria Timperio Carmine Mancone Marco Tripodi Michail Kapralov Eugene Krasavin Holger Kruse Jiří Šponer Judit E Šponer Václav Ranc Michal Otyepka Samanta Pino Ernesto Di Mauro

Chembiochem 2017 08 30;18(15):1535-1543. Epub 2017 Jun 30.

Department of Biology and Biotechnology, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.

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August 2017

SENP1 activity sustains cancer stem cell in hypoxic HCC.

Authors:
Alice Conigliaro Marco Tripodi Maurizio Parola

Gut 2017 12 13;66(12):2051-2052. Epub 2017 Apr 13.

Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.

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December 2017

MiR-675-5p supports hypoxia induced epithelial to mesenchymal transition in colon cancer cells.

Authors:
Viviana Costa Alessia Lo Dico Aroldo Rizzo Francesca Rajata Marco Tripodi Riccardo Alessandro Alice Conigliaro

Oncotarget 2017 Apr;8(15):24292-24302

Dipartimento di Biotecnologie Cellulari ed Ematologia, Sapienza University of Rome, Rome, Italy.

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April 2017

TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure.

Authors:
Marco De Santis Puzzonia Angela Maria Cozzolino Germana Grassi Francesca Bisceglia Raffaele Strippoli Giulia Guarguaglini Franca Citarella Benedetto Sacchetti Marco Tripodi Alessandra Marchetti Laura Amicone

PLoS One 2016 28;11(11):e0167158. Epub 2016 Nov 28.

Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Cellular Biotechnologies and Haematology, Sapienza University of Rome, Rome, Italy.

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August 2017

The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation.

Authors:
Lucia Cicchillitti Isabella Manni Carmine Mancone Giulia Regazzo Manuela Spagnuolo Tonino Alonzi Fabrizio Carlomosti Maria Lucia Dell'Anna Giulia Dell'Omo Mauro Picardo Paolo Ciana Maurizio C Capogrossi Marco Tripodi Alessandra Magenta Maria Giulia Rizzo Aymone Gurtner Giulia Piaggio

Oncotarget 2017 Jan;8(2):2628-2646

Department of Research, Advanced Diagnostics and Technological Innovation, SAFU Unit, Translational Research Area, Regina Elena National Cancer Institute, 00144 Rome, Italy.

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January 2017