Marco Medici

Marco Medici

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Marco Medici

Marco Medici

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The importance of high-quality mendelian randomisation studies for clinical thyroidology.

Lancet Diabetes Endocrinol 2019 Sep 7;7(9):665-667. Epub 2019 May 7.

Thyroid Research Group, Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK.

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http://dx.doi.org/10.1016/S2213-8587(19)30145-7DOI Listing
September 2019

Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment.

Thyroid 2019 Jun 13;29(6):760-777. Epub 2019 May 13.

8 Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1089/thy.2018.0416DOI Listing
June 2019

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-018-06356-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203810PMC
October 2018

Effects of Thyrotropin on Peripheral Thyroid Hormone Metabolism and Serum Lipids.

Thyroid 2018 02 1;28(2):168-174. Epub 2018 Feb 1.

1 Department of Internal Medicine, Academic Center for Thyroid Diseases, University Medical Center , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2017.0330DOI Listing
February 2018

Thyroid disease in pregnancy: new insights in diagnosis and clinical management.

Nat Rev Endocrinol 2017 Oct 4;13(10):610-622. Epub 2017 Aug 4.

Department of Internal Medicine, Erasmus Medical Center, Postbus 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/nrendo.2017.93DOI Listing
October 2017

Thyroid Function and Premature Delivery in TPO Antibody-Negative Women: The Added Value of hCG.

J Clin Endocrinol Metab 2017 09;102(9):3360-3367

Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00846DOI Listing
September 2017

A Step Forward in Understanding the Relevance of Genetic Variation in Type 2 Deiodinase.

J Clin Endocrinol Metab 2017 05;102(5):1775-1778

Department of Internal Medicine, Academic Center for Thyroid Disease, Erasmus Medical Center, Rotterdam 3015 GE, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00585DOI Listing
May 2017

Genetics of thyroid function.

Best Pract Res Clin Endocrinol Metab 2017 03 18;31(2):129-142. Epub 2017 Apr 18.

Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1521690X173003
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http://dx.doi.org/10.1016/j.beem.2017.04.002DOI Listing
March 2017

MANAGEMENT OF ENDOCRINE DISEASE: Isolated maternal hypothyroxinemia during pregnancy: knowns and unknowns.

Eur J Endocrinol 2017 Jan 15;176(1):R21-R38. Epub 2016 Aug 15.

Department of Endocrinology and Rotterdam Thyroid CenterErasmus Medical Center, Rotterdam, The Netherlands

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http://dx.doi.org/10.1530/EJE-16-0354DOI Listing
January 2017

The Risk of Preeclampsia According to High Thyroid Function in Pregnancy Differs by hCG Concentration.

J Clin Endocrinol Metab 2016 12 20;101(12):5037-5043. Epub 2016 Sep 20.

The Generation R Study Group (T.I.M.K., E.A.P.S., M.M., V.W.V.J.) and Departments of Internal Medicine (T.I.M.K., L.C., M.M., T.J.V., R.B.P.), Obstetrics and Gynecology (E.A.P.S.), Pediatrics (V.W.V.J.), Epidemiology (V.W.V.J.), and Clinical Chemistry (Y.B.d.R.), Erasmus Medical Center and/or Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands; and Rotterdam Thyroid Center (T.I.M.K., L.C., M.M., T.J.V., R.B.P.), Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2016-2397DOI Listing
December 2016

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.

J Clin Endocrinol Metab 2016 11 7;101(11):4270-4282. Epub 2016 Sep 7.

Departments of Internal Medicine (R.P.P., L.C., M.M.) and Epidemiology (R.P.P., O.H.F., A.D., A.H., A.I., L.C., M.L.P.P.), Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands; Rotterdam Thyroid Center (R.P.P., L.C., M.M.) and Department of Radiology and Neurology (M.A.I.), Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands; Department of General Internal Medicine (N.R., C.B., M.R.B.), Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; Service of Endocrinology, Diabetes, and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; Departments of Clinical Chemistry and Laboratory Medicine (W.P.J.d.E.), Public Health and Primary Care (J.G.), and Cardiology (W.J.), Leiden University Medical Center, 2300 RC Leiden, The Netherlands; Departments of Medicine and Epidemiology and Biostatistics (D.C.B.), University of California, San Francisco, San Francisco, California 94143; Division of Endocrinology, Diabetes, and Metabolism (A.R.C.), Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Epidemiology (A.H.), Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115; Department of Endocrinology (S.R.), Gateshead Health Foundation National Health Service Trust, Gateshead, SE18 4QH, United Kingdom; Department of Endocrinology and Diabetes (J.P.W.), Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia; Schools of Medicine and Pharmacology (J.P.W.) and Population Health (A.B.), University of Western Australia, Crawley, Western Australia 6009, Australia; National Council Research Institute of Clinical Physiology (G.I.), 56124 Pisa, Italy; Robertson Centre for Biostatistics (I.F.) and Institute of Cardiovascular and Medical Sciences (D.J.S.), Faculty of Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom; Department of Epidemiology (A.B.N.), University of Pittsburgh, Pittsburgh, Pennsylvania 15260; Department of Internal Medicine (S.J.L.B., R.P.D.), University Medical Center, University of Groningen, 9700 AB Groningen, The Netherlands; Department of Medicine (C.W., C.D.), Division of Nephrology, University Hospital of Würzburg, and Comprehensive Heart Failure Centre (C.W., C.D.), 97070 Würzburg, Germany; Department of Clinical Studies (M.I.), Radiation Effects Research Foundation, Nagasaki 850-8555, Japan; Department of Clinical and Experimental Medicine (G.C.), University of Parma, 143100 Parma, Italy; National Institute on Aging (L.F.), Baltimore, Maryland 21225; Institute for Community Medicine (H.V.), Clinical-Epidemiological Research/Study of Health in Pomerania, University Medicine, German Centre of Cardiovascular Research, Partner Site, Department of Internal Medicine (M.D.), and University Medicine (M.D.), German Centre of Cardiovascular Research, Partner Site, 17487 Greifswald, Germany; Departments of Neurology and Epidemiology (W.T.L.), and Cardiovascular Health Research Unit (W.T.L.), Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington 98108; Group Health Research Institute (B.M.P.), Group Health Cooperative, Seattle, Washington 98101; Division of Endocrinology (R.M.B.M., J.A.S.), Department of Medicine, Federal University of Sao Paulo, 05508-900 São Paulo, Brazil; Division of Endocrinology (J.A.S.), Faculdade de Medicina de Marília, Marília, Brazil; Department of Public Health and Primary Care (R.N.L., K.-T.K.), University of Cambridge, Cambridge CB2 1TN, United Kingdom; Interuniversity Cardiology Institute of The Netherlands (W.J.), 3508 GA Utrecht, The Netherlands; School of Clinical and Experimental Medicine (J.A.F.), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; and Department of Public Health and Center for Healthy Ageing (R.G.W.), Faculty of Health and Medical Sciences, University of Copenhagen, DK-2400 Copenhagen, Denmark.

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http://dx.doi.org/10.1210/jc.2016-2255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095234PMC
November 2016

Thyroid Function Characteristics and Determinants: The Rotterdam Study.

Thyroid 2016 09;26(9):1195-204

1 Rotterdam Thyroid Center, Erasmus University Medical Center , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2016.0133DOI Listing
September 2016

Association of antiepileptic drug usage, trace elements and thyroid hormone status.

Eur J Endocrinol 2016 Apr 23;174(4):425-32. Epub 2015 Dec 23.

Department of Internal MedicineRotterdam Thyroid CenterErasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The NetherlandsInstitut für Experimentelle EndokrinologieCharité-Universitätsmedizin Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany Department of Internal MedicineRotterdam Thyroid CenterErasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The NetherlandsInstitut für Experimentelle EndokrinologieCharité-Universitätsmedizin Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany

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http://www.eje-online.org/content/early/2015/12/23/EJE-15-10
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http://www.eje-online.org/lookup/doi/10.1530/EJE-15-1081
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http://dx.doi.org/10.1530/EJE-15-1081DOI Listing
April 2016

Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study.

Lancet Diabetes Endocrinol 2016 Jan 20;4(1):35-43. Epub 2015 Oct 20.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587150032
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http://dx.doi.org/10.1016/S2213-8587(15)00327-7DOI Listing
January 2016

Maternal and Birth Characteristics Are Determinants of Offspring Thyroid Function.

J Clin Endocrinol Metab 2016 Jan 19;101(1):206-13. Epub 2015 Nov 19.

The Generation R Study Group (T.I.M.K., V.W.V.J., M.M.) and Departments of Internal Medicine (T.I.M.K., L.C., T.J.V., M.M., R.P.P.), Pediatrics (V.W.V.J.), and Epidemiology (V.W.V.J.), Erasmus Medical Center-Sophia Children's Hospital, 3000 CA, Rotterdam, The Netherlands; and Rotterdam Thyroid Center (T.I.M.K., L.C., T.J.V., M.M., R.P.P.), Erasmus Medical Center, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-3559DOI Listing
January 2016

Long- versus short-interval follow-up of cytologically benign thyroid nodules: a prospective cohort study.

BMC Med 2016 Jan 27;14:11. Epub 2016 Jan 27.

The Thyroid Section, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, PBB-B4. Room 417, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12916-016-0554-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730757PMC
January 2016

The Influence of Patient Age on Thyroid Nodule Formation, Multinodularity, and Thyroid Cancer Risk.

J Clin Endocrinol Metab 2015 Dec 14;100(12):4434-40. Epub 2015 Oct 14.

Thyroid Section, Division of Endocrinology, Hypertension, and Diabetes (N.K., M.M., T.E.A., X.L., E.M., P.R.L., M.I.K., E.K.A.), and Department of Pathology (E.S.C., J.F.K., J.A.B.), The Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2015-3100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667162PMC
December 2015

Afirma Benign Thyroid Nodules Show Similar Growth to Cytologically Benign Nodules During Follow-Up.

J Clin Endocrinol Metab 2015 Nov 9;100(11):E1477-83. Epub 2015 Sep 9.

Thyroid Section (T.E.A., M.M., X.L., N.K., M.I.K., E.M.), Division of Endocrinology, Hypertension, and Diabetes, and Departments of Radiology (M.C.F.) and Pathology (E.S.C.), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115; Rotterdam Thyroid Center and Department of Internal Medicine (M.M.), Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands; and Department of Endocrinology (X.L.), First Affiliated Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu Province, China.

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http://dx.doi.org/10.1210/jc.2015-2658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702458PMC
November 2015

Subclinical Hypothyroidism Overdiagnosis in Pregnant Women.

JAMA Intern Med 2015 Nov;175(11):1872-3

Rotterdam Thyroid Center, Erasmus University Medical Center, the Netherlands.

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http://dx.doi.org/10.1001/jamainternmed.2015.5550DOI Listing
November 2015

The association of thyroid peroxidase antibody risk loci with susceptibility to and phenotype of Graves' disease.

Clin Endocrinol (Oxf) 2015 Oct 22;83(4):556-62. Epub 2014 Dec 22.

Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland.

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http://dx.doi.org/10.1111/cen.12640DOI Listing
October 2015

Placental Angiogenic Factors Are Associated With Maternal Thyroid Function and Modify hCG-Mediated FT4 Stimulation.

J Clin Endocrinol Metab 2015 Oct 23;100(10):E1328-34. Epub 2015 Jul 23.

The Generation R Study Group (T.I.M.K., V.W.V.J.); and Departments of Internal Medicine (T.I.M.K., Y.B.d.R., W.E.V., T.J.V., M.M., R.P.P.), Rotterdam Thyroid Center (T.I.M.K., W.E.V., T.J.V., M.M., R.P.P.), and Epidemiology (V.W.V.J.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; Departments of Obstetrics and Gynecology (E.A.P.S.), Clinical Chemistry (Y.B.d.R.), and Pediatrics (V.W.V.J.), Erasmus Medical Center-Sophia Children's Hospital, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-2553DOI Listing
October 2015

Normal Thyroid Function and the Risk of Atrial Fibrillation: the Rotterdam Study.

J Clin Endocrinol Metab 2015 Oct 11;100(10):3718-24. Epub 2015 Aug 11.

Rotterdam Thyroid Center (L.C., M.M., W.E.V., R.P.P.), Department of Internal Medicine (L.C., M.M., W.E.V., R.P.P.), and Department of Epidemiology (L.C., J.H., A.D., A.H., O.H.F.), Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands; and Department of General Internal Medicine (C.B., N.R.), Inselspital, University Hospital of Bern, 3010 Bern, Switzerland.

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http://dx.doi.org/10.1210/jc.2015-2480DOI Listing
October 2015

Reference ranges and determinants of total hCG levels during pregnancy: the Generation R Study.

Eur J Epidemiol 2015 Sep 12;30(9):1057-66. Epub 2015 May 12.

Department of Internal Medicine, Erasmus Medical Centre, Room D 430, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-015-0039-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584104PMC
September 2015

The variable phenotype and low-risk nature of RAS-positive thyroid nodules.

BMC Med 2015 Aug 7;13:184. Epub 2015 Aug 7.

Thyroid Section, Division of Endocrinology, Hypertension and Diabetes, The Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, PBB-B4 Room 417, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12916-015-0419-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528713PMC
August 2015

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis.

J Clin Endocrinol Metab 2015 Jun 9;100(6):2181-91. Epub 2015 Apr 9.

Department of Internal Medicine (L.C., M.M., R.P.P.), and Rotterdam Thyroid Center, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands; Department of Epidemiology (L.C., M.A.I., A.D., A.H., M.L.P.P., O.H.F.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Department of General Internal Medicine (C.B., M.R.B., N.R.), Inselspital, Bern University Hospital, 3010 Bern, Switzerland; Departments of Epidemiology, Public Health, and Primary Care (W.P.J.d.E., J.G.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Department of Radiology (M.A.I.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Department of Neurology (M.A.I., M.L.P.P.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Service of Endocrinology, Diabetes, and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; Department of Internal Medicine (S.J.L.B., R.P.D.), University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands; Department of Medicine (C.D., C.W.), Division of Nephrology, University Hospital of Würzburg, Germany Comprehensive Heart Failure Centre, D-97080 Würzburg, Germany; Department of Public Health and Primary Care (R.N.L., K.-T.K.), University of Cambridge, Cambridge CB2 1TN, United Kingdom; National Council Research Institute of Clinical Physiology (G.I.), Pisa 56124, Italy; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine (D.J.S.), and Robertson Centre for Biostatistics (I.F.), University of Glasgow, Glasgow G12 8QQ, United Kingdom; School of Population Health (A.B.), University of Western Australia, Crawley, Perth 6009, Western Australia, Australia; National Institute on Aging (L.F.), Baltimore, Maryland 20892; Department of Epidemiology (A.B.N.), University of Pittsburgh, Pittsburgh, Pennsylvania 15260; Division of Endocrinology (J.A.S.), Faculdade de Medicina de Marília, Marília, Sao Paulo 17519, Brazil; Di

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2015-1438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454799PMC
June 2015

A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations.

J Clin Endocrinol Metab 2015 May 26;100(5):E799-807. Epub 2015 Feb 26.

Renal Division (U.T.S., Y.L., A.K.), Department of Medicine IV, Medical Center, University of Freiburg, 79106 Freiburg, Germany; Department of Internal Medicine and Rotterdam Thyroid Center (M.M., L.C., A.G.U., R.P.P.) and Department of Epidemiology (L.C., A.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; Institute for Community Medicine (A.T., H.V.), Interfaculty Institute for Genetics and Functional Genomics (G.H.), and Institute of Clinical Chemistry and Laboratory Medicine (M.N.), University Medicine Greifswald, 17475 Greifswald, Germany; and Department of Epidemiology (N.D., E.S., A.K.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205.

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http://dx.doi.org/10.1210/jc.2014-4352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422885PMC
May 2015

Thyroid function in pregnancy: what is normal?

Clin Chem 2015 May 31;61(5):704-13. Epub 2015 Mar 31.

Department of Internal Medicine, Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1373/clinchem.2014.236646DOI Listing
May 2015

Genetic determination of the hypothalamic-pituitary-thyroid axis: where do we stand?

Endocr Rev 2015 Apr 9;36(2):214-44. Epub 2015 Mar 9.

Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/er.2014-1081DOI Listing
April 2015

Maternal early-pregnancy thyroid function is associated with subsequent hypertensive disorders of pregnancy: the generation R study.

J Clin Endocrinol Metab 2014 Dec;99(12):E2591-8

The Generation R Study Group (M.M., T.I.M.K., S.S.-T., R.G., V.W.V.J.) and Departments of Internal Medicine (M.M., T.I.M.K., Y.B.d.R., W.E.V., T.J.V., R.P.P.), Epidemiology (R.G., A.H., V.W.V.J.), and Immunology (H.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; and Departments of Obstetrics and Gynecology (S.S.-T., W.V., E.A.P.S.), Pediatrics (R.G., S.M.P.F.d.M.K.-S., J.J.B.-S., H.T., V.W.V.J.), Clinical Chemistry (Y.B.d.R.), and Child and Adolescent Psychiatry (H.T.), Erasmus Medical Center, Sophia Children's Hospital, 3000 DR Rotterdam, The Netherlands.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-1505DOI Listing
December 2014

Functional analysis of novel genetic variation in the thyroid hormone activating type 2 deiodinase.

J Clin Endocrinol Metab 2014 Nov 20;99(11):E2429-36. Epub 2014 Aug 20.

Department of Internal Medicine (C.Z., W.K., R.P.P., M.M., Y.B.d.R., M.E.M., T.J.V., W.E.V.), Rotterdam Thyroid Center (C.Z., W.K., R.P.P., M.M., M.E.M., T.J.V., W.E.V.), Department of Clinical Chemistry (Y.B.d.R.), Erasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands; Prinsenstichting (S.A.H.), Kwadijkerpark 8, 1444 JE Purmerend, The Netherlands; Ipse De Bruggen (H.G., E.B.), Spoorlaan 19, 2471 PB Zwammerdam, The Netherlands; Vanboeijenoord (G.d.K.), Industrieweg 14-16, 9400 RA Assen, The Netherlands; 's Heeren Loo Groot Schuilenburg (K.H.d.W.), Laan Van Groot Schuylenburg 310-320, 7325 BG Apeldoorn, The Netherlands; and Department of Internal Medicine (R.L.), Brigham and Women's Hospital, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2014-2281DOI Listing
November 2014

Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis.

Eur J Epidemiol 2014 Nov 2;29(11):791-800. Epub 2014 Sep 2.

Department of Internal Medicine, Thyroid Center, Erasmus University Medical Center, Room Ee502, PO Box 2040, 3000 CA, Rotterdam, The Netherlands,

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http://link.springer.com/content/pdf/10.1007%2Fs10654-014-99
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http://link.springer.com/10.1007/s10654-014-9946-8
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http://dx.doi.org/10.1007/s10654-014-9946-8DOI Listing
November 2014

Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study.

J Clin Endocrinol Metab 2014 Sep 2;99(9):E1627-34. Epub 2014 Jun 2.

The Generation R Study Group (T.I.M.K., S.S.-T., V.W.V.J., M.M.) and Departments of Internal Medicine (T.I.M.K., Y.B.d.R., W.E.V., T.J.V., M.M., R.P.P.), Rotterdam Thyroid Center (T.I.M.K., W.E.V., T.J.V., M.M., R.P.P.), Epidemiology (S.L., A.H., H.T., V.W.V.J.), and Immunology (H.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; and Departments of Obstetrics and Gynecology (E.A.P.S., S.S.-T., W.V.), Clinical Chemistry (Y.B.d.R., H.R.), Endocrinology (S.M.P.F.d.M.K.-S., J.J.B.-S.), Pediatrics (V.W.V.J.), and Child and Adolescent Psychiatry (H.T.), Erasmus Medical Center, Sophia Children's Hospital, 3015 GJ Rotterdam, The Netherlands.

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September 2014

Thyroid function within the normal range and the risk of depression: a population-based cohort study.

J Clin Endocrinol Metab 2014 Apr 24;99(4):1213-9. Epub 2014 Feb 24.

Departments of Internal Medicine (M.M., W.E.V., T.I.M.K., T.J.V., R.P.P.) and Epidemiology (N.D., A.H., H.T.), Erasmus Medical Center, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2013-3589DOI Listing
April 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Ethnic differences in maternal thyroid parameters during pregnancy: the Generation R study.

J Clin Endocrinol Metab 2013 Sep 8;98(9):3678-86. Epub 2013 Jul 8.

The Generation R Study Group and Department of Internal Medicine, Erasmus Medical Center, 3015 GE, Rotterdam, The Netherlands.

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September 2013

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Authors:
Eleonora Porcu Marco Medici Giorgio Pistis Claudia B Volpato Scott G Wilson Anne R Cappola Steffan D Bos Joris Deelen Martin den Heijer Rachel M Freathy Jari Lahti Chunyu Liu Lorna M Lopez Ilja M Nolte Jeffrey R O'Connell Toshiko Tanaka Stella Trompet Alice Arnold Stefania Bandinelli Marian Beekman Stefan Böhringer Suzanne J Brown Brendan M Buckley Clara Camaschella Anton J M de Craen Gail Davies Marieke C H de Visser Ian Ford Tom Forsen Timothy M Frayling Laura Fugazzola Martin Gögele Andrew T Hattersley Ad R Hermus Albert Hofman Jeanine J Houwing-Duistermaat Richard A Jensen Eero Kajantie Margreet Kloppenburg Ee M Lim Corrado Masciullo Stefano Mariotti Cosetta Minelli Braxton D Mitchell Ramaiah Nagaraja Romana T Netea-Maier Aarno Palotie Luca Persani Maria G Piras Bruce M Psaty Katri Räikkönen J Brent Richards Fernando Rivadeneira Cinzia Sala Mona M Sabra Naveed Sattar Beverley M Shields Nicole Soranzo John M Starr David J Stott Fred C G J Sweep Gianluca Usala Melanie M van der Klauw Diana van Heemst Alies van Mullem Sita H Vermeulen W Edward Visser John P Walsh Rudi G J Westendorp Elisabeth Widen Guangju Zhai Francesco Cucca Ian J Deary Johan G Eriksson Luigi Ferrucci Caroline S Fox J Wouter Jukema Lambertus A Kiemeney Peter P Pramstaller David Schlessinger Alan R Shuldiner Eline P Slagboom André G Uitterlinden Bijay Vaidya Theo J Visser Bruce H R Wolffenbuttel Ingrid Meulenbelt Jerome I Rotter Tim D Spector Andrew A Hicks Daniela Toniolo Serena Sanna Robin P Peeters Silvia Naitza

PLoS Genet 2013 7;9(2):e1003266. Epub 2013 Feb 7.

Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567175PMC
June 2013

Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R Study.

J Clin Endocrinol Metab 2013 Jan 12;98(1):59-66. Epub 2012 Nov 12.

Department of Internal Medicine, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2012-2420DOI Listing
January 2013

Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism.

Eur J Endocrinol 2012 Dec 18;167(6):809-15. Epub 2012 Sep 18.

Department of Endocrinology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1530/EJE-12-0501DOI Listing
December 2012

Underestimation of effect of thyroid function parameters on morbidity and mortality due to intra-individual variation.

J Clin Endocrinol Metab 2011 Dec 14;96(12):E2014-7. Epub 2011 Sep 14.

Department of Endocrinology (471), Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1210/jc.2011-0680DOI Listing
December 2011

Preliminary evidence that a functional polymorphism in type 1 deiodinase is associated with enhanced potentiation of the antidepressant effect of sertraline by triiodothyronine.

J Affect Disord 2009 Jul 6;116(1-2):113-6. Epub 2008 Dec 6.

Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.jad.2008.10.019DOI Listing
July 2009

BMP-2 gene polymorphisms and osteoporosis: the Rotterdam Study.

J Bone Miner Res 2006 Jun;21(6):845-54

Department of Internal Medicine Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1359/jbmr.060306DOI Listing
June 2006