Marco Herling

Marco Herling

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Marco Herling

Marco Herling

Publications by authors named "Marco Herling"

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Migration Properties Distinguish Tumor Cells of Classical Hodgkin Lymphoma from Anaplastic Large Cell Lymphoma Cells.

Cancers (Basel) 2019 Oct 2;11(10). Epub 2019 Oct 2.

Dr. Senckenberg Institute of Pathology, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/cancers11101484DOI Listing
October 2019

Severely Itching Dermatitis and Palmoplantar Keratoderma as First Manifestation of T-cell Prolympho-cytic Leukaemia.

Acta Derm Venereol 2019 Aug 13. Epub 2019 Aug 13.

Department of Dermatology, Allergology, and Dermatosurgery, HELIOS University Hospital Wuppertal, University of Witten/Herdecke, DE-42283 Wuppertal, Germany.

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http://dx.doi.org/10.2340/00015555-3288DOI Listing
August 2019

The dawn of a new era in treating T-PLL.

Oncotarget 2019 Jan 18;10(6):626-628. Epub 2019 Jan 18.

Laboratory of Lymphocyte Signaling and Oncoproteome, Department of Internal Medicine I, Center for Integrated Oncology Köln-Bonn, University of Cologne, Cologne, Germany; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.18632/oncotarget.26595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363017PMC
January 2019

Nucleotide excision repair as a targetable vulnerability in leukemia.

Oncotarget 2017 Dec 6;8(70):114420-114421. Epub 2017 Dec 6.

Laboratory of Lymphocyte Signaling and Oncoproteome, Department of Internal Medicine I, Center for Integrated Oncology Köln-Bonn, University of Cologne, Cologne, Germany; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.18632/oncotarget.22998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777699PMC
December 2017

Semi-automated cancer genome analysis using high-performance computing.

Hum Mutat 2017 10 17;38(10):1325-1335. Epub 2017 Jul 17.

Bioinformatics Core Facility, Cluster of Excellence on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/humu.23275DOI Listing
October 2017

Restoration of DAP Kinase Tumor Suppressor Function: A Therapeutic Strategy to Selectively Induce Apoptosis in Cancer Cells Using Immunokinase Fusion Proteins.

Biomedicines 2017 Oct 4;5(4). Epub 2017 Oct 4.

South African Research Chair in Cancer Biotechnology, Institute of Infectious Disease and Molecular Medicine, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7700, South Africa.

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http://dx.doi.org/10.3390/biomedicines5040059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744083PMC
October 2017

Activity of the CD40 antagonistic antibody lucatumumab - insights from CLL-niche mimicking xenografts and fludarabine combinations.

Leuk Lymphoma 2016 09 12;57(9):2235-8. Epub 2016 Jan 12.

a Department of Medicine I, Laboratory of Lymphocyte Signaling and Oncoproteome, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD) , University of Cologne , Germany ;

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http://dx.doi.org/10.3109/10428194.2015.1135433DOI Listing
September 2016

A Novel Recombinant Anti-CD22 Immunokinase Delivers Proapoptotic Activity of Death-Associated Protein Kinase (DAPK) and Mediates Cytotoxicity in Neoplastic B Cells.

Mol Cancer Ther 2016 05 29;15(5):971-84. Epub 2016 Jan 29.

Laboratory of Lymphocyte Signaling and Oncoproteome, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), University of Cologne, Köln, Germany. Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, and CECAD, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0685DOI Listing
May 2016

CD1d-restricted peripheral T cell lymphoma in mice and humans.

J Exp Med 2016 05 11;213(5):841-57. Epub 2016 Apr 11.

CIRI, International Center for Infectiology Research, Université de Lyon, 69007 Lyon, France Institut National de la Santé et de la Recherche Médicale (INSERM), U1111, 69007 Lyon, France Ecole Normale Supérieure de Lyon, 69007 Lyon, France Université Lyon 1, Centre International de Recherche en Infectiologie, 69007 Lyon, France Centre National de la Recherche Scientifique (CNRS), UMR 5308, 69365 Lyon, France

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http://dx.doi.org/10.1084/jem.20150794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854725PMC
May 2016

Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL: updated results of the CLL8 trial.

Blood 2016 Jan 20;127(2):208-15. Epub 2015 Oct 20.

Department I for Internal Medicine and Center of Integrated Oncology, University of Cologne, Cologne, Germany; Cluster of Excellence Cellular Stress Responses in Aging Associated Diseases, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1182/blood-2015-06-651125DOI Listing
January 2016

Vitamin D controls apoptosis and proliferation of cutaneous T-cell lymphoma cells.

Exp Dermatol 2015 Oct 22;24(10):798-800. Epub 2015 May 22.

Department of Dermatology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1111/exd.12746DOI Listing
October 2015

AKT-pathway inhibition in chronic lymphocytic leukemia reveals response relationships defined by TCL1.

Curr Cancer Drug Targets 2014 ;14(8):700-12

Laboratory of Lymphocyte Signaling and Oncoproteome, Center for Integrated Oncology (CIO) Köln- Bonn and Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Germany.

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July 2015

Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden.

Mol Cancer 2015 Jun 4;14:114. Epub 2015 Jun 4.

Laboratory of Lymphocyte Signaling and Oncoproteome, Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, and Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1186/s12943-015-0378-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453051PMC
June 2015

Interleukin-2-inducible T-cell kinase (ITK) targeting by BMS-509744 does not affect cell viability in T-cell prolymphocytic leukemia (T-PLL).

J Biol Chem 2015 Apr;290(16):10568-9

Laboratory of Lymphocyte Signaling and Oncoproteome, Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, and Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1074/jbc.L115.644641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400363PMC
April 2015

Are we improving the outcome for patients with T-cell prolymphocytic leukemia by allogeneic stem cell transplantation?

Authors:
Marco Herling

Eur J Haematol 2015 Mar;94(3):191-2

Laboratory of Lymphocyte Signaling and Oncoproteome, Center for Integrated Oncology (CIO) Köln-Bonn and Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1111/ejh.12462DOI Listing
March 2015

Multilevel BCR signals toward CLL.

Blood 2015 Mar;125(10):1510-2

UNIVERSITY OF COLOGNE.

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http://dx.doi.org/10.1182/blood-2015-01-621227DOI Listing
March 2015

Models for mature T-cell lymphomas--a critical appraisal of experimental systems and their contribution to current T-cell tumorigenic concepts.

Crit Rev Oncol Hematol 2013 Dec 21;88(3):680-95. Epub 2013 Aug 21.

Laboratory of lymphocyte signaling and oncoproteome, CECAD, Cologne University, Cologne, Germany; Senckenberg Institute of Pathology, Goethe-University, Frankfurt/M., Germany.

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http://dx.doi.org/10.1016/j.critrevonc.2013.07.014DOI Listing
December 2013

T-cell receptor signaling in peripheral T-cell lymphoma - a review of patterns of alterations in a central growth regulatory pathway.

Curr Hematol Malig Rep 2013 Sep;8(3):163-72

Laboratory for Lymphocyte Signaling and Oncoproteome, Department I of Internal Medicine, Center for Integrated Oncology Köln-Bonn, Cologne, Germany.

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http://dx.doi.org/10.1007/s11899-013-0165-2DOI Listing
September 2013

CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia.

Blood 2013 May 1;121(20):4126-36. Epub 2013 Apr 1.

Department I of Internal Medicine, Center for Integrated Oncology Cologne-Bonn, and Cluster of Excellence, Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1182/blood-2012-11-466250DOI Listing
May 2013

Targeting the disturbed redox equilibrium in chronic lymphocytic leukemia by novel reactive oxygen species-catalytic 'sensor/effector' compounds.

Leuk Lymphoma 2011 Jul 29;52(7):1407-11. Epub 2011 Mar 29.

Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln Bonn, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.3109/10428194.2011.568077DOI Listing
July 2011

Pharmacologic interception in T-cell leukemia 1A associated pathways as a treatment rationale for chronic lymphocytic leukemia.

Leuk Lymphoma 2010 Aug;51(8):1375-8

Department of Medicine I, Cologne University, Cologne, Germany.

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http://dx.doi.org/10.3109/10428194.2010.505064DOI Listing
August 2010

High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia.

Blood 2009 Nov 21;114(21):4675-86. Epub 2009 Sep 21.

Department of Hematopathology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2009-03-208256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780304PMC
November 2009

Skin involvement in T-cell prolymphocytic leukemia.

J Am Acad Dermatol 2007 Sep;57(3):533-4

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http://dx.doi.org/10.1016/j.jaad.2007.02.034DOI Listing
September 2007

TCL1 in B-cell tumors retains its normal b-cell pattern of regulation and is a marker of differentiation stage.

Am J Surg Pathol 2007 Jul;31(7):1123-9

Department of Hematopathology, The University of Texas, M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1097/PAS.0b013e31802e2201DOI Listing
July 2007

TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation.

Proc Natl Acad Sci U S A 2007 Jun 4;104(24):10175-80. Epub 2007 Jun 4.

Department of Human Genetics, and Jonsson Comprehensive Cancer Center, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0704170104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891214PMC
June 2007

CD4+/CD56+ hematodermic tumor: the features of an evolving entity and its relationship to dendritic cells.

Am J Clin Pathol 2007 May;127(5):687-700

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

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http://dx.doi.org/10.1309/FY6PK436NBK0RYD4DOI Listing
May 2007

Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms.

Mod Pathol 2006 Dec 22;19(12):1555-62. Epub 2006 Sep 22.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://www.nature.com/articles/3800679
Publisher Site
http://dx.doi.org/10.1038/modpathol.3800679DOI Listing
December 2006

T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation.

J Immunol 2005 Jul;175(2):864-73

Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.4049/jimmunol.175.2.864DOI Listing
July 2005

Primary Sézary syndrome commonly shows low-grade cytologic atypia and an absence of epidermotropism.

Am J Clin Pathol 2005 Apr;123(4):510-5

Department of Pathology, the University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

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http://dx.doi.org/10.1309/YB79-JG4T-MJER-Q7PVDOI Listing
April 2005

T-cell prolymphocytic leukemia involving extramedullary sites.

Am J Clin Pathol 2005 Mar;123(3):456-64

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

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http://dx.doi.org/10.1309/93P4-2RNG-5XBG-3KBEDOI Listing
March 2005

A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories.

Blood 2004 Jul 25;104(2):328-35. Epub 2004 Mar 25.

Department of Hematopathology, Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-01-00
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http://dx.doi.org/10.1182/blood-2004-01-0002DOI Listing
July 2004

Retinoblastoma protein is frequently absent or phosphorylated in anaplastic large-cell lymphoma.

Am J Pathol 2004 Jun;164(6):2259-67

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615788PMC
http://dx.doi.org/10.1016/S0002-9440(10)63782-0DOI Listing
June 2004

Absence of Epstein-Barr virus in anaplastic large cell lymphoma: a study of 64 cases classified according to World Health Organization criteria.

Hum Pathol 2004 Apr;35(4):455-9

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.humpath.2003.10.013DOI Listing
April 2004

Caspase-3 activation in systemic anaplastic large-cell lymphoma.

Mod Pathol 2004 Jan;17(1):109-16

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.modpathol.3800039DOI Listing
January 2004

Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma.

Clin Cancer Res 2003 Sep;9(10 Pt 1):3692-9

Department of Hematopathology, University of Texas, M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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September 2003

TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin.

Blood 2003 Jun 6;101(12):5007-9. Epub 2003 Feb 6.

Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston 77030, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2002-10-32
Publisher Site
http://dx.doi.org/10.1182/blood-2002-10-3297DOI Listing
June 2003

Combined radiofrequency thermal ablation and percutaneous cementoplasty treatment of a pathologic fracture.

J Vasc Interv Radiol 2002 Oct;13(10):1047-50

Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55, D 79106, Freiburg, Germany.

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http://dx.doi.org/10.1016/s1051-0443(07)61872-7DOI Listing
October 2002