Marco Donia

Marco Donia

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Marco Donia

Marco Donia

Publications by authors named "Marco Donia"

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The real-world impact of modern treatments on the survival of patients with metastatic melanoma.

Eur J Cancer 2019 Feb 31;108:25-32. Epub 2018 Dec 31.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, Herlev, Denmark; Department of Oncology, Herlev Hospital, Herlev, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183153
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http://dx.doi.org/10.1016/j.ejca.2018.12.002DOI Listing
February 2019

Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.

Br J Cancer 2019 Feb 5;120(4):424-434. Epub 2019 Feb 5.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://www.nature.com/articles/s41416-019-0384-y
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http://dx.doi.org/10.1038/s41416-019-0384-yDOI Listing
February 2019

Acquired resistance to cancer immunotherapy.

Semin Immunopathol 2019 01 2;41(1):31-40. Epub 2018 Jul 2.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00281-018-0692-yDOI Listing
January 2019

Principles of adoptive T cell therapy in cancer.

Semin Immunopathol 2019 01 5;41(1):49-58. Epub 2018 Sep 5.

Center for Cancer Immune Therapy, Department of Hematology, Copenhagen University Hospital, Entrance 81, Floor 05, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00281-018-0703-zDOI Listing
January 2019

Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses: implications for the management of irAEs.

Int J Cancer 2018 Dec 21. Epub 2018 Dec 21.

Department of Hematology, Center for Cancer Immune Therapy, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1002/ijc.32080DOI Listing
December 2018

Correction: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Oncotarget 2018 Nov 9;9(88):35870. Epub 2018 Nov 9.

Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.18632/oncotarget.26359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254673PMC
November 2018

Cancer immunotherapy in patients with brain metastases.

Cancer Immunol Immunother 2018 May 8;67(5):703-711. Epub 2018 Mar 8.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-018-2146-8DOI Listing
May 2018

[Cancer immunotherapy].

Ugeskr Laeger 2018 May;180(21)

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May 2018

T-cell Responses in the Microenvironment of Primary Renal Cell Carcinoma-Implications for Adoptive Cell Therapy.

Cancer Immunol Res 2018 02 4;6(2):222-235. Epub 2018 Jan 4.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0467DOI Listing
February 2018

Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab.

Oncoimmunology 2018 1;7(5):e1424674. Epub 2018 Feb 1.

Institute for Inflammation Research, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2018.1424674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927482PMC
February 2018

Frequent adaptive immune responses against arginase-1.

Oncoimmunology 2018 26;7(3):e1404215. Epub 2017 Dec 26.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1080/2162402X.2017.1404215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790367PMC
December 2017

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.

Nat Commun 2017 11 23;8(1):1738. Epub 2017 Nov 23.

Division of Oncology and Pathology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Scheelegatan 2, Medicon Village, 22185, Lund, Sweden.

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http://dx.doi.org/10.1038/s41467-017-01460-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701046PMC
November 2017

PD-1 Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer.

Clin Cancer Res 2017 Oct 5;23(19):5779-5788. Epub 2017 Jul 5.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1692DOI Listing
October 2017

Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model.

Nat Commun 2017 09 27;8(1):707. Epub 2017 Sep 27.

From the Sahlgrenska Translational Melanoma Group, Institute of Clinical Science, Departments of Surgery and Oncology, Sahlgrenska Cancer Center at University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, 405 30, Sweden.

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http://dx.doi.org/10.1038/s41467-017-00786-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617838PMC
September 2017

Cancer immunotherapy in patients with preexisting autoimmune disorders.

Semin Immunopathol 2017 04 11;39(3):333-337. Epub 2016 Oct 11.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00281-016-0595-8DOI Listing
April 2017

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Oncotarget 2017 Apr;8(16):27062-27074

Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.18632/oncotarget.16003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432318PMC
April 2017

The majority of patients with metastatic melanoma are not represented in pivotal phase III immunotherapy trials.

Eur J Cancer 2017 03 12;74:89-95. Epub 2017 Feb 12.

Center for Cancer Immune Therapy, Department of Hematology, Herlev, Denmark; Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S09598049173002
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http://dx.doi.org/10.1016/j.ejca.2016.12.017DOI Listing
March 2017

Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma.

Hum Vaccin Immunother 2015 ;11(12):2790-5

a Center for Cancer Immune Therapy ; Department of Hematology; Herlev Hospital; Copenhagen University ; Copenhagen , Denmark.

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http://dx.doi.org/10.1080/21645515.2015.1075106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054777PMC
September 2016

CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment.

Oncoimmunology 2016 30;5(11):e1238541. Epub 2016 Sep 30.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2016.1238541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139648PMC
September 2016

Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen.

Clin Cancer Res 2016 08 22;22(15):3734-45. Epub 2016 Mar 22.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark. Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1879DOI Listing
August 2016

PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine.

Oncoimmunology 2016 Aug 1;5(8):e1202391. Epub 2016 Jul 1.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2016.1202391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007957PMC
August 2016

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.

Science 2016 Jun 19;352(6291):1337-41. Epub 2016 May 19.

Division of Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.

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http://dx.doi.org/10.1126/science.aaf2288DOI Listing
June 2016

The controversial role of TNF in melanoma.

Oncoimmunology 2016 Apr 29;5(4):e1107699. Epub 2015 Oct 29.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1080/2162402X.2015.1107699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839341PMC
April 2016

Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity.

Cancer Res 2015 Sep 16;75(18):3747-59. Epub 2015 Jul 16.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark. Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://cancerres.aacrjournals.org/content/early/2015/07/16/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-2956DOI Listing
September 2015

Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies.

Drug Discov Today 2015 Sep 17;20(9):1127-34. Epub 2015 Jul 17.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2015.07.003DOI Listing
September 2015

New developments in the management of advanced melanoma - role of pembrolizumab.

Onco Targets Ther 2015 14;8:2535-43. Epub 2015 Sep 14.

Department of Pathology, Cannizzaro Hospital, Catania, Italy.

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http://dx.doi.org/10.2147/OTT.S72823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576895PMC
September 2015

Broadening the repertoire of melanoma-associated T-cell epitopes.

Cancer Immunol Immunother 2015 May 18;64(5):609-20. Epub 2015 Feb 18.

Center for Cancer Immune Therapy, Department of Hematology, University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-015-1664-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412285PMC
May 2015

"Immunotherapy of cancer: present status and future promise": Danish Cancer Society Symposium, Copenhagen, Denmark, 23rd-25th September 2013.

Cancer Immunol Immunother 2014 Sep 24;63(9):985-9. Epub 2014 Jul 24.

Department of Hematology 65Q9, Center for Cancer Immune Therapy, University Hospital Herlev, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-014-1585-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141144PMC
September 2014

Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor.

Cytotherapy 2014 Aug 13;16(8):1117-20. Epub 2014 May 13.

Center for Cancer Immune Therapy, Department of Hematology, Herlev, Denmark; Department of Oncology, Herlev Hospital, Herlev, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2014.02.004DOI Listing
August 2014

Effector CD4 and CD8 T cells and their role in the tumor microenvironment.

Cancer Microenviron 2013 Aug 16;6(2):123-33. Epub 2012 Dec 16.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Herlev University Hospital, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s12307-012-0127-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717059PMC
August 2013

Biological insights into BRAF mutations in melanoma patient: Not mere therapeutic targets.

Oncoimmunology 2013 Aug 3;2(8):e25594. Epub 2013 Jul 3.

Laboratory of Clinical Research and Molecular Diagnostics; IRCCS - CROB Centro di Riferimento Oncologico della Basilicata; Rionero in Vulture (Pz), Italy.

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http://dx.doi.org/10.4161/onci.25594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812198PMC
August 2013

HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients.

Cancer Res 2013 Mar 17;73(6):1764-76. Epub 2013 Jan 17.

Center for Cancer Immune Therapy, Department of Hematology and Oncology, Copenhagen University Hospital, Herlev, Herlev Ringvej, Herlev, Denmark.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3507DOI Listing
March 2013

Methods to improve adoptive T-cell therapy for melanoma: IFN-γ enhances anticancer responses of cell products for infusion.

J Invest Dermatol 2013 Feb 27;133(2):545-52. Epub 2012 Sep 27.

Department of Haematology, Center for Cancer Immune Therapy, Copenhagen University Hospital at Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1038/jid.2012.336DOI Listing
February 2013

Comparative study of rapamycin and temsirolimus demonstrates superimposable anti-tumour potency on prostate cancer cells.

Basic Clin Pharmacol Toxicol 2013 Jan 26;112(1):63-9. Epub 2012 Jul 26.

Department of Bio-Medical Sciences, School of Medicine, University of Catania, 95124 Catania, Italy.

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http://dx.doi.org/10.1111/j.1742-7843.2012.00923.xDOI Listing
January 2013

Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy.

Vaccine 2013 Jan 29;31(4):639-46. Epub 2012 Nov 29.

Center for Cancer Immune Therapy, Department of Haematology, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1016/j.vaccine.2012.11.053DOI Listing
January 2013

BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer.

Oncoimmunology 2012 Dec;1(9):1476-1483

Center for Cancer Immune Therapy; Department of Haematology; Copenhagen University Hospital at Herlev; Herlev, Denmark ; Department of Biomedical Sciences; University of Catania; Catania, Italy.

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http://dx.doi.org/10.4161/onci.21940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525603PMC
December 2012

Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes.

Oncoimmunology 2012 Nov;1(8):1297-1304

Center for Cancer Immune Therapy; Department of Haematology; Copenhagen University Hospital at Herlev; Herlev, Denmark ; Department of Biomedical Sciences; University of Catania; Catania, Italy.

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http://dx.doi.org/10.4161/onci.21659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518502PMC
November 2012

Breast cancer: Molecular basis and therapeutic strategies (Review).

Mol Med Rep 2008 Jul-Aug;1(4):451-8

Department of Biomedical Sciences, University of Catania, I-95124 Catania, Italy.

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October 2012

Therapeutic potential of nitric oxide-modified drugs in colon cancer cells.

Mol Pharmacol 2012 Oct 13;82(4):700-10. Epub 2012 Jul 13.

Department of Immunology, Institute for Biological Research "Sinisa Stankovic", Belgrade University, Belgrade, Serbia.

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http://dx.doi.org/10.1124/mol.112.077842DOI Listing
October 2012

Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.

PLoS One 2012 23;7(4):e34568. Epub 2012 Apr 23.

Department of Hematology and Oncology, Center for Cancer Immune Therapy, Copenhagen University Hospital, Herlev, Herlev, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335144PMC
September 2012

Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion.

Cancer Immunol Immunother 2012 Aug 12;61(8):1221-31. Epub 2012 Jan 12.

Department of Hematology 54P4, Center for Cancer Immune Therapy, University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-011-1199-8DOI Listing
August 2012

Eleventh international conference on progress in vaccination against cancer (PIVAC-11), 10-13 October 2011, Copenhagen, Denmark.

Cancer Immunol Immunother 2012 Aug 5;61(8):1349-53. Epub 2012 Feb 5.

Department of Hematology, Center for Cancer Immune Therapy (CCIT), Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-012-1209-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401499PMC
August 2012

Dissection of T-cell antigen specificity in human melanoma.

Cancer Res 2012 Apr 6;72(7):1642-50. Epub 2012 Feb 6.

Department of Hematology, Center for Cancer Immune Therapy and Oncology, University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2614DOI Listing
April 2012

Potential use of rapamycin in HIV infection.

Br J Clin Pharmacol 2010 Dec;70(6):784-93

Department of Biomedical Sciences, University of Catania, Italy.

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http://dx.doi.org/10.1111/j.1365-2125.2010.03735.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014061PMC
December 2010

New perspectives in HCV therapy: entry inhibitors.

Recent Pat Antiinfect Drug Discov 2010 Nov;5(3):181-94

Department of Biomedical Sciences, School of Medicine, University of Catania, Italy.

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November 2010

In vitro inhibition of enterobacteria-reactive CD4+CD25- T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027.

Eur J Pharmacol 2008 May 17;586(1-3):313-21. Epub 2008 Feb 17.

Department of Biomedical Sciences, Section of Clinical Pathology and Molecular Oncology, University of Catania, Italy.

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http://dx.doi.org/10.1016/j.ejphar.2008.02.017DOI Listing
May 2008