Publications by authors named "Marco Daniele Parenti"

17Publications

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.

Mol Divers 2020 Aug 25;24(3):655-671. Epub 2019 Jun 25.

Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, V.le Benedetto XV 1, 16132, Genoa, Italy.

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August 2020

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

Bioorg Med Chem 2017 10 19;25(20):5849-5858. Epub 2017 Sep 19.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy. Electronic address:

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October 2017

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.

Eur J Med Chem 2015 Sep 14;102:530-9. Epub 2015 Aug 14.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy; Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129 Bologna, Italy. Electronic address:

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September 2015

Selectivity hot-spots of sirtuin catalytic cores.

Mol Biosyst 2015 Aug;11(8):2263-72

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Alma Mater Studiorum, Via S.Giacomo 14, 40126 Bologna, Italy.

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August 2015

Discovery of novel and selective SIRT6 inhibitors.

J Med Chem 2014 Jun 19;57(11):4796-804. Epub 2014 May 19.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna , Via S. Giacomo 14, 40126 Bologna, Italy.

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June 2014

Rejuvenating sirtuins: the rise of a new family of cancer drug targets.

Curr Pharm Des 2013 ;19(4):614-23

Room 221, Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.

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July 2013

Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives.

Curr Pharm Des 2013 ;19(4):578-613

Department of Experimental Pathology, Alma Mater Studiorum - University of Bologna, Via S.Giacomo 14, 40126 Bologna, Italy.

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July 2013

Advances and applications of binding affinity prediction methods in drug discovery.

Biotechnol Adv 2012 Jan-Feb;30(1):244-50. Epub 2011 Aug 12.

Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Modena, Italy.

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July 2012

BEAR, a novel virtual screening methodology for drug discovery.

J Biomol Screen 2011 Jan 17;16(1):129-33. Epub 2010 Nov 17.

Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Modena, Italy.

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January 2011

A computational workflow for the design of irreversible inhibitors of protein kinases.

J Comput Aided Mol Des 2010 Mar 21;24(3):183-94. Epub 2010 Mar 21.

Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Via Campi 183, 41100, Modena, Italy.

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March 2010

Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement.

Bioorg Med Chem Lett 2003 Oct;13(19):3257-60

Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy.

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October 2003

Docking and database screening reveal new classes of Plasmodium falciparum dihydrofolate reductase inhibitors.

J Med Chem 2003 Jul;46(14):2834-45

Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy.

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July 2003