Marco Colonna

Marco Colonna

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Marco Colonna

Publications by authors named "Marco Colonna"

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Leukemia Inhibitory Factor Inhibits Plasmacytoid Dendritic Cell Function and Development.

J Immunol 2020 Mar 13. Epub 2020 Mar 13.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110; and

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http://dx.doi.org/10.4049/jimmunol.1900604DOI Listing
March 2020

ILC2s are the predominant source of intestinal ILC-derived IL-10.

J Exp Med 2020 Feb;217(2)

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1084/jem.20191520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041711PMC
February 2020

Sense and immuno-sensibility: innate lymphoid cell niches and circuits.

Curr Opin Immunol 2020 Feb 9;62:9-14. Epub 2019 Dec 9.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2019.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067671PMC
February 2020

Neuroinflammation and neurodegeneration in human brain at single-cell resolution.

Nat Rev Immunol 2020 Feb;20(2):81-82

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1038/s41577-019-0262-0DOI Listing
February 2020

Brain Parenchymal and Extraparenchymal Macrophages in Development, Homeostasis, and Disease.

J Immunol 2020 Jan;204(2):294-305

Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110

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http://dx.doi.org/10.4049/jimmunol.1900821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034672PMC
January 2020

DC-SCRIPT deficiency delays mouse mammary gland development and branching morphogenesis.

Dev Biol 2019 Nov 29;455(1):42-50. Epub 2019 Jun 29.

Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2019.06.023DOI Listing
November 2019

ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands.

J Exp Med 2019 Oct 11;216(10):2231-2241. Epub 2019 Jul 11.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO

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http://dx.doi.org/10.1084/jem.20180549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781001PMC
October 2019

The Microglial Response to Neurodegenerative Disease.

Adv Immunol 2018 9;139:1-50. Epub 2018 May 9.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ai.2018.04.002DOI Listing
September 2019

TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.

Neuron 2019 09 10;103(5):820-835.e7. Epub 2019 Jul 10.

Genetics and Aging Research Unit, McCance Center for Brain Health, Mass General Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728215PMC
September 2019

TREM1 Blockade: Killing Two Birds with One Stone.

Authors:
Marco Colonna

Trends Immunol 2019 Sep 20;40(9):781-783. Epub 2019 Aug 20.

Washington University School of Medicine, St Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.07.008DOI Listing
September 2019

TREM2 function impedes tau seeding in neuritic plaques.

Nat Neurosci 2019 08 24;22(8):1217-1222. Epub 2019 Jun 24.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-019-0433-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660358PMC
August 2019

Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence.

Elife 2019 08 20;8. Epub 2019 Aug 20.

Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St Louis, United States.

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http://dx.doi.org/10.7554/eLife.46677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701943PMC
August 2019

Microglia in Alzheimer's disease: A target for immunotherapy.

J Leukoc Biol 2019 Jul 6;106(1):219-227. Epub 2019 Feb 6.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA.

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http://dx.doi.org/10.1002/JLB.MR0818-319RDOI Listing
July 2019

Fifty Shades of Microglia.

Trends Neurosci 2019 Jul 18;42(7):440-443. Epub 2019 Apr 18.

Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2019.03.010DOI Listing
July 2019

Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells.

Sci Rep 2019 05 17;9(1):7508. Epub 2019 May 17.

Department of Genome-based Drug Discovery, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, 852-8521, Japan.

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http://dx.doi.org/10.1038/s41598-019-43535-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525155PMC
May 2019

Innate Lymphoid Cells in Mucosal Immunity.

Front Immunol 2019 7;10:861. Epub 2019 May 7.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00861
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http://dx.doi.org/10.3389/fimmu.2019.00861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515929PMC
May 2019

The Natural Cytotoxicity Receptors in Health and Disease.

Front Immunol 2019 7;10:909. Epub 2019 May 7.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00909
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http://dx.doi.org/10.3389/fimmu.2019.00909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514059PMC
May 2019

Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors.

J Exp Med 2019 Apr 21;216(4):884-899. Epub 2019 Mar 21.

Oklahoma Medical Research Foundation, Program in Arthritis and Clinical Immunology, Oklahoma City, OK

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http://dx.doi.org/10.1084/jem.20182100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446881PMC
April 2019

TREM2 triggers microglial density and age-related neuronal loss.

Glia 2019 03 11;67(3):539-550. Epub 2018 Dec 11.

Neural Regeneration, Institute of Reconstructive Neurobiology, University Hospital of Bonn, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1002/glia.23563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266PMC
March 2019

Innate lymphoid cell sensing of tissue vitality.

Curr Opin Immunol 2019 02 5;56:82-93. Epub 2018 Dec 5.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469350PMC
February 2019

IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation.

Proc Natl Acad Sci U S A 2019 02 29;116(7):2646-2651. Epub 2019 Jan 29.

Center for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology, Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;

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http://dx.doi.org/10.1073/pnas.1815016116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377481PMC
February 2019

Innate lymphoid cells: A potential link between microbiota and immune responses against cancer.

Semin Immunol 2019 02 20;41:101271. Epub 2019 Mar 20.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10445323183011
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http://dx.doi.org/10.1016/j.smim.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731134PMC
February 2019

The CNS Immune-Privilege Goes Down the Drain(age).

Trends Pharmacol Sci 2019 01 5;40(1):1-3. Epub 2018 Dec 5.

Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2018.11.006DOI Listing
January 2019

Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells.

Cell 2019 01 27;176(1-2):348-360.e12. Epub 2018 Dec 27.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.11.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329660PMC
January 2019

Exploiting NK Cell Surveillance Pathways for Cancer Therapy.

Cancers (Basel) 2019 Jan 8;11(1). Epub 2019 Jan 8.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.3390/cancers11010055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356551PMC
January 2019

TREM2 - a key player in microglial biology and Alzheimer disease.

Nat Rev Neurol 2018 11;14(11):667-675

Washington University School of Medicine, St Louis, MO, USA.

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http://www.nature.com/articles/s41582-018-0072-1
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http://dx.doi.org/10.1038/s41582-018-0072-1DOI Listing
November 2018

Introduction: Basic and emerging concepts in ILC biology.

Authors:
Marco Colonna

Immunol Rev 2018 11;286(1):4-5

Washington University School of Medicine, St Louis, Missouri.

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http://doi.wiley.com/10.1111/imr.12711
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http://dx.doi.org/10.1111/imr.12711DOI Listing
November 2018

High-affinity interactions and signal transduction between Aβ oligomers and TREM2.

EMBO Mol Med 2018 11;10(11)

Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience, University of Florida, Gainesville, FL, USA

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http://dx.doi.org/10.15252/emmm.201809027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220267PMC
November 2018

Is There Natural Killer Cell Memory and Can It Be Harnessed by Vaccination? Vaccination Strategies Based on NK Cell and ILC Memory.

Cold Spring Harb Perspect Biol 2018 10 1;10(10). Epub 2018 Oct 1.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110.

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http://dx.doi.org/10.1101/cshperspect.a029512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169813PMC
October 2018

The identity and function of microglia in neurodegeneration.

Nat Immunol 2018 10 24;19(10):1048-1058. Epub 2018 Sep 24.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.

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http://www.nature.com/articles/s41590-018-0212-1
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http://dx.doi.org/10.1038/s41590-018-0212-1DOI Listing
October 2018

LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection.

Cell Host Microbe 2018 08;24(2):249-260.e4

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA; Division of Biology, University of California San Diego, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132068PMC
August 2018

Innate Lymphoid Cells: 10 Years On.

Cell 2018 08;174(5):1054-1066

Department of Experimental Immunology Academic Medical Center of the University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2018.07.017DOI Listing
August 2018

AHR signaling in the development and function of intestinal immune cells and beyond.

Semin Immunopathol 2018 07 27;40(4):371-377. Epub 2018 Jun 27.

Department of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s00281-018-0694-9DOI Listing
July 2018

TREM2-Dependent Effects on Microglia in Alzheimer's Disease.

Front Aging Neurosci 2018 9;10:202. Epub 2018 Jul 9.

Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, United States.

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http://dx.doi.org/10.3389/fnagi.2018.00202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046445PMC
July 2018

Innate Lymphoid Cells: Diversity, Plasticity, and Unique Functions in Immunity.

Authors:
Marco Colonna

Immunity 2018 06;48(6):1104-1117

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344351PMC
June 2018

Mechanisms of Action and Clinical Development of Elotuzumab.

Clin Transl Sci 2018 05 22;11(3):261-266. Epub 2017 Dec 22.

Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1111/cts.12532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944582PMC
May 2018

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.

Cell 2018 05;173(5):1073-1081

Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183057
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http://dx.doi.org/10.1016/j.cell.2018.05.003DOI Listing
May 2018

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.

J Exp Med 2018 03 10;215(3):745-760. Epub 2018 Jan 10.

Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO

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http://dx.doi.org/10.1084/jem.20171529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839761PMC
March 2018

Chemical sensing in development and function of intestinal lymphocytes.

Curr Opin Immunol 2018 02 14;50:112-116. Epub 2018 Feb 14.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.01.004DOI Listing
February 2018

Immune Training Unlocks Innate Potential.

Cell 2018 01;172(1-2):3-5

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674173151
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http://dx.doi.org/10.1016/j.cell.2017.12.034DOI Listing
January 2018

Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection.

Cell Rep 2017 Nov;21(9):2528-2540

Department of Molecular Medicine II, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173160
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http://dx.doi.org/10.1016/j.celrep.2017.11.001DOI Listing
November 2017

Two Distinct Myeloid Subsets at the Term Human Fetal-Maternal Interface.

Front Immunol 2017 25;8:1357. Epub 2017 Oct 25.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, United States.

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http://dx.doi.org/10.3389/fimmu.2017.01357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662895PMC
October 2017

SMAD4 impedes the conversion of NK cells into ILC1-like cells by curtailing non-canonical TGF-β signaling.

Nat Immunol 2017 Sep 31;18(9):995-1003. Epub 2017 Jul 31.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ni.3809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712491PMC
September 2017

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.

Cell 2017 Jun 8;169(7):1276-1290.e17. Epub 2017 Jun 8.

Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.05.018DOI Listing
June 2017

Tailoring Natural Killer cell immunotherapy to the tumour microenvironment.

Semin Immunol 2017 06 19;31:30-36. Epub 2017 Sep 19.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659759PMC
June 2017

Expression of CD226 is associated to but not required for NK cell education.

Nat Commun 2017 05 31;8:15627. Epub 2017 May 31.

Department of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, F59, 14186 Stockholm, Sweden.

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http://dx.doi.org/10.1038/ncomms15627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460037PMC
May 2017

Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.

Alzheimers Dement 2017 Apr 9;13(4):381-387. Epub 2016 Aug 9.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299056PMC
April 2017

Microglia Function in the Central Nervous System During Health and Neurodegeneration.

Annu Rev Immunol 2017 04 9;35:441-468. Epub 2017 Feb 9.

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; email:

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http://dx.doi.org/10.1146/annurev-immunol-051116-052358DOI Listing
April 2017

Elucidating the Role of TREM2 in Alzheimer's Disease.

Neuron 2017 Apr;94(2):237-248

Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.02.042DOI Listing
April 2017

The ILC World Revisited.

Immunity 2017 03;46(3):327-332

German Rheumatism Research Center, A Leibniz Institute, Charitéplatz 1, D-10117 Berlin, Germany; Medical Department I, Charité-University Medical Center Berlin, Hindenburgdamm 30, D-12203 Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613173008
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http://dx.doi.org/10.1016/j.immuni.2017.03.008DOI Listing
March 2017

IL-15 sustains IL-7R-independent ILC2 and ILC3 development.

Nat Commun 2017 03 31;8:14601. Epub 2017 Mar 31.

Department of Pathology &Immunology, Washington University School of Medicine, 509 S. Euclid Ave Box 8118, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/ncomms14601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380969PMC
March 2017

Editorial Overview: Sense and react: how the innate immune system detects threats and generates protective responses.

Authors:
Marco Colonna

Curr Opin Immunol 2017 02;44:v-vii

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, United States.

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http://dx.doi.org/10.1016/j.coi.2017.05.001DOI Listing
February 2017

Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.

Elife 2016 12 20;5. Epub 2016 Dec 20.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Washington University School of Medicine, St. Louis, United States.

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https://elifesciences.org/articles/20391
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http://dx.doi.org/10.7554/eLife.20391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173322PMC
December 2016

Diversity and function of group 1 innate lymphoid cells.

Immunol Lett 2016 11 6;179:19-24. Epub 2016 Jul 6.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658203PMC
November 2016

Immune modules shared by innate lymphoid cells and T cells.

J Allergy Clin Immunol 2016 11;138(5):1243-1251

Department of Pathology & Immunology, Washington University School of Medicine, St Louis, Mo. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111630PMC
November 2016

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.

Immunity 2016 10;45(4):817-830

Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535820PMC
October 2016

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease.

Nat Microbiol 2016 Oct 31;2:16196. Epub 2016 Oct 31.

Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/nmicrobiol.2016.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308540PMC
October 2016

MHC II+ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes.

J Exp Med 2016 09 22;213(10):1951-9. Epub 2016 Aug 22.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110

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http://dx.doi.org/10.1084/jem.20160486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030807PMC
September 2016

The Transcription Factor AP4 Mediates Resolution of Chronic Viral Infection through Amplification of Germinal Center B Cell Responses.

Immunity 2016 09 23;45(3):570-582. Epub 2016 Aug 23.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037962PMC
September 2016

Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection.

J Exp Med 2016 08 8;213(9):1835-50. Epub 2016 Aug 8.

Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia

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http://dx.doi.org/10.1084/jem.20151899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995080PMC
August 2016

Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease.

J Immunol 2016 07 25;197(1):42-50. Epub 2016 May 25.

Centers for Therapeutic Innovation, Pfizer, Inc., Boston, MA 02115.

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http://dx.doi.org/10.4049/jimmunol.1502190DOI Listing
July 2016

Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis.

PLoS Negl Trop Dis 2016 06 2;10(6):e0004747. Epub 2016 Jun 2.

Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1371/journal.pntd.0004747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890812PMC
June 2016

Innate lymphoid cell function in the context of adaptive immunity.

Nat Immunol 2016 06;17(7):783-9

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ni.3484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156404PMC
June 2016

IMMUNOLOGY. Converting to adapt.

Science 2016 Jun;352(6293):1515-6

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.aag1719
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http://dx.doi.org/10.1126/science.aag1719DOI Listing
June 2016

Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells.

Cell Metab 2016 05;23(5):852-66

Laboratory of Cellular Physiology and Immunology, Institut de Recherches Cliniques de Montréal, Montréal, QC H2W 1R7, Canada; Division of Experimental Medicine, Department of Medicine, McGill University, Montréal, QC H3A 1A3, Canada; Department of Microbiology, Infectiology, and Immunology, Université de Montréal, Montréal, QC H3C 3J7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.010DOI Listing
May 2016

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Neuron 2016 05;90(4):724-39

Department of Neurology, Yale University, New Haven, CT 06511, USA; Department of Neuroscience, Yale University, New Haven, CT 06511, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898967PMC
May 2016

Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2.

Nat Microbiol 2016 04 25;1(6):16054. Epub 2016 Apr 25.

Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1038/nmicrobiol.2016.54DOI Listing
April 2016