Publications by authors named "Marco A Marra"

100Publications

Whole-slide laser microdissection for tumour enrichment.

J Pathol 2020 Nov 2. Epub 2020 Nov 2.

Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.5575DOI Listing
November 2020

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L.

BMC Biol 2020 Oct 28;18(1):154. Epub 2020 Oct 28.

Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1186/s12915-020-00895-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594423PMC
October 2020

Epigenomic programming in early fetal brain development.

Epigenomics 2020 Jun 17;12(12):1053-1070. Epub 2020 Jul 17.

Department of Microbiology & Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.

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http://dx.doi.org/10.2217/epi-2019-0319DOI Listing
June 2020

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Nature 2019 10 9;574(7780):707-711. Epub 2019 Oct 9.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-019-1650-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141958PMC
October 2019

The pivotal role of sampling recurrent tumors in the precision care of patients with tumors of the central nervous system.

Cold Spring Harb Mol Case Stud 2019 08 1;5(4). Epub 2019 Aug 1.

Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada.

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http://dx.doi.org/10.1101/mcs.a004143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672021PMC
August 2019

Temporal Dynamics of Genomic Alterations in a Germline-Mutated Pancreatic Cancer With Low Genomic Instability Burden but Exceptional Response to Fluorouracil, Oxaliplatin, Leucovorin, and Irinotecan.

JCO Precis Oncol 2018 19;2. Epub 2018 Oct 19.

, , , , , , , , , , , , and , British Columbia Cancer Agency; , , , , and , Pancreas Centre BC; and , Simon Fraser University; , , , , , and , University of British Columbia; and , Vancouver General Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1200/PO.18.00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446469PMC
October 2018

Magnetic-resonance-imaging-based three-dimensional muscle reconstruction of hip abductor muscle volume in a person with a transfemoral bone-anchored prosthesis: A feasibility study.

Physiother Theory Pract 2019 May 28;35(5):495-504. Epub 2018 Mar 28.

b Radboud Institute for Health Sciences, Orthopaedic Research Laboratory , Radboud University Medical Centre , Nijmegen , Netherlands.

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http://dx.doi.org/10.1080/09593985.2018.1453902DOI Listing
May 2019

In situ comparison of A-mode ultrasound tracking system and skin-mounted markers for measuring kinematics of the lower extremity.

J Biomech 2018 04 10;72:134-143. Epub 2018 Mar 10.

Orthopaedic Research Lab, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jbiomech.2018.03.007DOI Listing
April 2018

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.

Dev Cell 2018 03 15;44(6):709-724.e6. Epub 2018 Mar 15.

Center for Neuropathology, Ludwig-Maximilians-University, 81377 Munich, Germany; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, N63 (HPI), Hamburg 20251, Germany; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.02.012DOI Listing
March 2018

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Cell 2018 02;172(5):1050-1062.e14

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346737PMC
February 2018

Assessment of Capture and Amplicon-Based Approaches for the Development of a Targeted Next-Generation Sequencing Pipeline to Personalize Lymphoma Management.

J Mol Diagn 2018 03 8;20(2):203-214. Epub 2018 Feb 8.

Centre for Lymphoid Cancer, BC Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.11.010DOI Listing
March 2018

Specific muscle strength is reduced in facioscapulohumeral dystrophy: An MRI based musculoskeletal analysis.

Neuromuscul Disord 2018 03 12;28(3):238-245. Epub 2017 Dec 12.

Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud university medical center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Biomechanical Engineering, University of Twente, Postbus 217, 7500 AE Enschede, The Netherlands.

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http://dx.doi.org/10.1016/j.nmd.2017.11.017DOI Listing
March 2018

MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia.

J Clin Oncol 2017 Dec 25;35(35):3964-3977. Epub 2017 Oct 25.

Emilia L. Lim, Diane L. Trinh, Yussanne Ma, James Topham, Erin Pleasance, Andrew J. Mungall, Richard Moore, Yongjun Zhao, and Marco A. Marra, Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency; Marco A. Marra, University of British Columbia, Vancouver, British Columbia; Lillian Sung, The Hospital for Sick Children, Toronto, Ontario, Canada; Rhonda E. Ries, Maya Hughes, and Soheil Meshinchi, Fred Hutchinson Cancer Research Center; Rhonda E. Ries, Maya Hughes, and Soheil Meshinchi, University of Washington, Seattle, WA; Jim Wang, Robert B. Gerbing, E. Anders Kolb, Alan Gamis, and Todd A. Alonzo, Children's Oncology Group, Monrovia; Todd A. Alonzo, University of Southern California, Los Angeles, CA; Richard Aplenc, The Children's Hospital of Philadelphia, Philadelphia, PA; Malcolm Smith and Daniela S. Gerhard, Office of Cancer Genomics, National Cancer Institute, Bethesda, MD; and Robert J. Arceci, Phoenix Children's Hospital, Phoenix. AZ.

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http://dx.doi.org/10.1200/JCO.2017.74.7451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721230PMC
December 2017

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Cancer Cell 2017 09;32(3):295-309.e12

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600520PMC
September 2017

Characterization of the human thyroid epigenome.

J Endocrinol 2017 Nov 14;235(2):153-165. Epub 2017 Aug 14.

Canada's Michael Smith Genome Sciences CentreBC Cancer Agency, Vancouver, Canada

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http://dx.doi.org/10.1530/JOE-17-0145DOI Listing
November 2017

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

Whole-genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia.

Exp Hematol 2017 09 8;53:48-58. Epub 2017 Jun 8.

Institut National de la Santé et de la Recherche Médicale (INSERM) U935, Villejuif, France; Service d'Hématologie Biologique, Institut Federatif d'Hematologie Interpôle Paris Sud-IFHIPS (AP-HP) Kremlin Bicêtre, Paris, France; Université Paris-Sud, Faculté de Médecine Kremlin Bicêtre, and INSERM UMS 33, Villejuif, France; Human Pluripotent Stem Cell Core Facility, ESTeam Paris Sud-INGESTEM, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.05.007DOI Listing
September 2017

Anterior referencing of tibial slope in total knee arthroplasty considerably influences knee kinematics: a musculoskeletal simulation study.

Knee Surg Sports Traumatol Arthrosc 2018 May 12;26(5):1540-1548. Epub 2017 May 12.

Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00167-017-4561-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907627PMC
May 2018

Evaluation of a Surrogate Contact Model in Force-Dependent Kinematic Simulations of Total Knee Replacement.

J Biomech Eng 2017 Aug;139(8)

Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud University Medical Center, P. O. Box 9101, Nijmegen 6500 HB, The Netherlands;Department of Biomechanical Engineering, University of Twente, P. O. Box 217, Enschede 7500 AE, The Netherlands e-mail:

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http://dx.doi.org/10.1115/1.4036605DOI Listing
August 2017

Sequencing Strategies to Guide Decision Making in Cancer Treatment.

PLoS Med 2016 Dec 6;13(12):e1002189. Epub 2016 Dec 6.

Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, Canada.

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http://dx.doi.org/10.1371/journal.pmed.1002189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140043PMC
December 2016

Intragenic CNVs for epigenetic regulatory genes in intellectual disability: Survey identifies pathogenic and benign single exon changes.

Am J Med Genet A 2016 11;170(11):2916-2926

Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/ajmg.a.37669DOI Listing
November 2016