Publications by authors named "Marcin Wlodarski"

79Publications

DNA Repair Syndromes and Cancer: Insights Into Genetics and Phenotype Patterns.

Front Pediatr 2020 23;8:570084. Epub 2020 Oct 23.

Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fped.2020.570084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644847PMC
October 2020

Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.

Best Pract Res Clin Haematol 2020 Sep 29;33(3):101197. Epub 2020 Jul 29.

Department of Hematology, St. Jude Children's Research Hospital, Memphis, USA; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.beha.2020.101197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388796PMC
September 2020

Androgen derivatives improve blood counts and elongate telomere length in adult cryptic dyskeratosis congenita.

Br J Haematol 2020 Aug 3. Epub 2020 Aug 3.

Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.16997DOI Listing
August 2020

A Novel Deletion in the RPL5 Gene in a Lebanese Child With Diamond Blackfan Anemia Unresponsive to Steroid Treatment.

J Pediatr Hematol Oncol 2020 05;42(4):e235-e237

Department of Pediatrics, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0000000000001435DOI Listing
May 2020

Impaired human hematopoiesis due to a cryptic intronic splicing mutation.

J Exp Med 2019 05 26;216(5):1050-1060. Epub 2019 Mar 26.

Division of Hematology/Oncology, The Manton Center for Orphan Disease Research, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

View Article

Download full-text PDF

Source
http://www.jem.org/lookup/doi/10.1084/jem.20181625
Publisher Site
http://dx.doi.org/10.1084/jem.20181625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504223PMC
May 2019

A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia.

SLAS Discov 2019 03;24(3):304-313

1 Department of Molecular Medicine and Gene Therapy, Lund Strategic Center for Stem Cell Biology, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2472555218823531DOI Listing
March 2019

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia.

Leukemia 2019 07 24;33(7):1805-1810. Epub 2019 Jan 24.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41375-018-0343-2DOI Listing
July 2019

Complexities of genetic diagnosis illustrated by an atypical case of congenital hypoplastic anemia.

Cold Spring Harb Mol Case Stud 2018 12 17;4(6). Epub 2018 Dec 17.

Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/mcs.a003384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318771PMC
December 2018

Monosomy 7 in Pediatric Myelodysplastic Syndromes.

Hematol Oncol Clin North Am 2018 Aug;32(4):729-743

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Faculty of Medicine, Medical Center, University of Freiburg, Mathildenstr.1, Freiburg 79106, Germany; German Cancer Consortium (DKTK), Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hoc.2018.04.007DOI Listing
August 2018

Clonal PIGA mosaicism and dynamics in paroxysmal nocturnal hemoglobinuria.

Leukemia 2018 11 25;32(11):2507-2511. Epub 2018 Apr 25.

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41375-018-0138-5DOI Listing
November 2018

Mutational Spectrum of Fanconi Anemia Associated Myeloid Neoplasms.

Klin Padiatr 2017 Nov 13;229(6):329-334. Epub 2017 Nov 13.

Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0043-117046DOI Listing
November 2017

Molecular approaches to diagnose Diamond-Blackfan anemia: The EuroDBA experience.

Eur J Med Genet 2018 Nov 26;61(11):664-673. Epub 2017 Oct 26.

Laboratory Genetic Metabolic Diseases, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmg.2017.10.017DOI Listing
November 2018

Heterogeneity of GATA2-related myeloid neoplasms.

Int J Hematol 2017 Aug 22;106(2):175-182. Epub 2017 Jun 22.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12185-017-2285-2DOI Listing
August 2017

GATA2 deficiency and related myeloid neoplasms.

Semin Hematol 2017 04 10;54(2):81-86. Epub 2017 May 10.

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.seminhematol.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650112PMC
April 2017

Introduction: Genetic syndromes predisposing to myeloid neoplasia.

Semin Hematol 2017 04 4;54(2):57-59. Epub 2017 May 4.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology; Medical Center; Faculty of Medicine, University of Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, Germany, and German Cancer Research Center (DKFZ), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.seminhematol.2017.05.001DOI Listing
April 2017

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.38142DOI Listing
April 2017

Transient myeloproliferative disorder in an infant with PTPN11 mutation.

Br J Haematol 2017 04 20;177(1):11. Epub 2017 Jan 20.

Department of Haematology, Our Lady's Children's Hospital, Dublin, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.14517DOI Listing
April 2017

Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome.

Haematologica 2016 06 24;101(6):707-16. Epub 2016 Mar 24.

CLIP-Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2015.137711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013954PMC
June 2016

Discrimination of T-cell subsets and T-cell receptor repertoire distribution.

Immunol Res 2014 Jan;58(1):20-7

Institute of Medical Immunology, Charité-University Medicine, Campus Virchow-Klinikum, Institutsgebäude Süd, Föhrer Str. 15/Südstr. 2, 13353, Berlin, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12026-013-8473-0DOI Listing
January 2014

Hemangioblastomas and neurogenic polyglobulia.

Neurosurgery 2013 Jun;72(6):930-5; discussion 935

Department of Neurosurgery, Freiburg University Medical Center, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1227/NEU.0b013e31828ba793DOI Listing
June 2013

Tricky B-usiness: hematogones in aplastic anemia.

Authors:
Marcin Wlodarski

Leuk Lymphoma 2009 Dec;50(12):1905-6

Department of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10428190903406814DOI Listing
December 2009

Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia.

Haematologica 2009 Oct;94(10):1407-14

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2009.009191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754957PMC
October 2009

Clonotype analysis of cytomegalovirus-specific cytotoxic T lymphocytes.

J Am Soc Nephrol 2009 Feb 17;20(2):344-52. Epub 2008 Sep 17.

Experimental Haematology and Hematopoiesis Section, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1681/ASN.2007111225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637041PMC
February 2009

Clonal predominance of CD8(+) T cells in patients with unexplained neutropenia.

Exp Hematol 2008 Mar;36(3):293-300

Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center of the Cleveland Clinic, Cleveland, OH 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2007.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643087PMC
March 2008

Detection of cryptic chromosomal lesions including acquired segmental uniparental disomy in advanced and low-risk myelodysplastic syndromes.

Exp Hematol 2007 Nov 17;35(11):1728-38. Epub 2007 Oct 17.

Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2007.08.009DOI Listing
November 2007

CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS).

Blood 2007 Aug 5;110(3):847-50. Epub 2007 Apr 5.

Department of Hematological Medicine, King's College London, Rayne Institute, 123 Coldharbour Lane, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-01-067546DOI Listing
August 2007

T-large granular lymphocyte leukemia: current molecular concepts.

Hematology 2006 Aug;11(4):245-56

Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10245330600774793DOI Listing
August 2006

Pathophysiology defined by altered signal transduction pathways: the role of JAK-STAT and PI3K signaling in leukemic large granular lymphocytes.

Cell Cycle 2006 Nov 15;5(22):2571-4. Epub 2006 Nov 15.

Section of Experimental Hematology and Hematopoiesis, Taussig Cancer Center, Cleveland Clinic, Cleveland, Ohio 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.5.22.3449DOI Listing
November 2006

Immunogenetic factors determining the evolution of T-cell large granular lymphocyte leukaemia and associated cytopenias.

Br J Haematol 2007 Jan 30;136(2):237-48. Epub 2006 Nov 30.

Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center, Cleveland Clnic, Cleveland, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2141.2006.06429.xDOI Listing
January 2007

Killer immunoglobulin-like receptor genotype in immune-mediated bone marrow failure syndromes.

Exp Hematol 2005 Nov;33(11):1357-62

Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center, Cleveland, OH 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2005.07.005DOI Listing
November 2005

Efficient identification of T-cell clones associated with graft-versus-host disease in target tissue allows for subsequent detection in peripheral blood.

Br J Haematol 2005 May;129(3):411-9

The Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1365-2141.2005.05472.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2141.2005.05472.xDOI Listing
May 2005

Shared and individual specificities of immunodominant cytotoxic T-cell clones in paroxysmal nocturnal hemoglobinuria as determined by molecular analysis.

Exp Hematol 2004 Mar;32(3):261-9

Experimental Hematology and Hematopoiesis Section, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2003.11.011DOI Listing
March 2004

Molecular analysis of TCR clonotypes in LGL: a clonal model for polyclonal responses.

J Immunol 2004 Feb;172(3):1960-9

Experimental Hematology and Hematopoiesis Section, and Hematopathology Section, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.172.3.1960DOI Listing
February 2004

Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens.

Blood 2002 May;99(10):3668-75

Hematology Branch of the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood.v99.10.3668DOI Listing
May 2002