Marcelo O Dietrich

Marcelo O Dietrich

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Marcelo O Dietrich

Marcelo O Dietrich

Publications by authors named "Marcelo O Dietrich"

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Activation of Agrp neurons modulates memory-related cognitive processes in mice.

Pharmacol Res 2019 Jan 2. Epub 2019 Jan 2.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06520, USA; Graduate Program in Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90035, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10436618183193
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http://dx.doi.org/10.1016/j.phrs.2018.12.024DOI Listing
January 2019

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.

Elife 2017 08 1;6. Epub 2017 Aug 1.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, United States.

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http://dx.doi.org/10.7554/eLife.25755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538821PMC
August 2017

AgRP Neurons Regulate Bone Mass.

Cell Rep 2015 Oct 24;13(1):8-14. Epub 2015 Sep 24.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868421PMC
October 2015

Hypothalamic POMC neurons promote cannabinoid-induced feeding.

Nature 2015 Mar 18;519(7541):45-50. Epub 2015 Feb 18.

1] Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520, USA [3] Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA [4] Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1038/nature14260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496586PMC
March 2015

Hypothalamic Agrp neurons drive stereotypic behaviors beyond feeding.

Cell 2015 Mar 5;160(6):1222-32. Epub 2015 Mar 5.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Kavli Institute for Neuroscience at Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.cell.2015.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484787PMC
March 2015

O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat.

Cell 2014 Oct;159(2):306-17

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Section of Comparative Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509746PMC
October 2014

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.

Nat Neurosci 2014 Jul 1;17(7):908-10. Epub 2014 Jun 1.

1] Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA. [2] Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA. [3] Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113214PMC
July 2014

Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center.

Mol Metab 2012 18;1(1-2):79-85. Epub 2012 Aug 18.

Program in Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA ; Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.molmet.2012.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757645PMC
September 2013

Visualizing browning in vivo.

Mol Metab 2013 17;2(3):126-7. Epub 2013 Jul 17.

Section of Comparative Medicine, Yale University, New Haven, CT 06520, USA ; Department of Biochemistry, UFRGS, Porto Alegre, RS 90035, Brazil.

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http://dx.doi.org/10.1016/j.molmet.2013.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773728PMC
September 2013

Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.

Cell 2013 Sep;155(1):172-87

Diabetes and Obesity Research Laboratory, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain; Department of Endocrinology and Nutrition, Hospital Clínic. School of Medicine, University of Barcelona, 08036 Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), 08036 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cell.2013.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839088PMC
September 2013

Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity.

Cell 2013 Sep;155(1):188-99

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90035, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674130109
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http://dx.doi.org/10.1016/j.cell.2013.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142434PMC
September 2013

Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses.

Proc Natl Acad Sci U S A 2013 Apr 25;110(15):6193-8. Epub 2013 Mar 25.

Dipartimento di Medicina e Chirurgia, Università degli Studi di Salerno, 84081 Salerno, Italy.

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http://dx.doi.org/10.1073/pnas.1210644110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625304PMC
April 2013

Hypothalamic control of energy balance: insights into the role of synaptic plasticity.

Trends Neurosci 2013 Feb 12;36(2):65-73. Epub 2013 Jan 12.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01662236120022
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http://dx.doi.org/10.1016/j.tins.2012.12.005DOI Listing
February 2013

A marriage made to last in drug design.

Nat Med 2012 Dec;18(12):1737-8

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http://dx.doi.org/10.1038/nm.3018DOI Listing
December 2012

Phosphoribosomes for fingerprinting neurons.

Cell 2012 Nov;151(5):934-6

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674120134
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http://dx.doi.org/10.1016/j.cell.2012.11.006DOI Listing
November 2012

Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons.

Nat Rev Drug Discov 2012 Sep 3;11(9):675-91. Epub 2012 Aug 3.

Program in Integrative Cell Signalling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1038/nrd3739DOI Listing
September 2012

Sirtuin 1 and sirtuin 3: physiological modulators of metabolism.

Physiol Rev 2012 Jul;92(3):1479-514

Department of Physiology, School of Medicine-Instituto de Investigaciones Sanitarias, University of Santiago de Compostela, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1152/physrev.00022.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746174PMC
July 2012

AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors.

Nat Neurosci 2012 Jun 24;15(8):1108-10. Epub 2012 Jun 24.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.3147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411867PMC
June 2012

Fat incites tanycytes to neurogenesis.

Nat Neurosci 2012 Apr 25;15(5):651-3. Epub 2012 Apr 25.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.3091DOI Listing
April 2012

Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation.

Cell Metab 2012 Feb 26;15(2):247-55. Epub 2012 Jan 26.

The Saban Research Institute, Neuroscience Program, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131120000
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http://dx.doi.org/10.1016/j.cmet.2011.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278575PMC
February 2012

AgRP neurons: the foes of reproduction in leptin-deficient obese subjects.

Proc Natl Acad Sci U S A 2012 Feb 9;109(8):2699-700. Epub 2012 Feb 9.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1121355109
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http://dx.doi.org/10.1073/pnas.1121355109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286927PMC
February 2012

Obesity is associated with hypothalamic injury in rodents and humans.

J Clin Invest 2012 Jan 27;122(1):153-62. Epub 2011 Dec 27.

Division of Metabolism, Endocrinology and Nutrition, Diabetes and Obesity Center of Excellence, University of Washington, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1172/JCI59660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248304PMC
January 2012

Synaptic plasticity of feeding circuits: hormones and hysteresis.

Cell 2011 Sep;146(6):863-5

Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286741101000
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http://dx.doi.org/10.1016/j.cell.2011.08.031DOI Listing
September 2011

Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.

J Neurosci 2010 Sep;30(35):11815-25

Program on Cell and Neurobiology of Energy Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2234-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965459PMC
September 2010

The role of mitochondrial uncoupling proteins in lifespan.

Pflugers Arch 2010 Jan 17;459(2):269-75. Epub 2009 Sep 17.

Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1007/s00424-009-0729-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809791PMC
January 2010

Feeding signals and brain circuitry.

Eur J Neurosci 2009 Nov 28;30(9):1688-96. Epub 2009 Oct 28.

Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2009.06963.xDOI Listing
November 2009

GABA keeps up an appetite for life.

Cell 2009 Jun;137(7):1177-9

Program on Cell and Neurobiology of Energy Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.cell.2009.06.002DOI Listing
June 2009

Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation.

J Neurosci 2008 Oct;28(42):10766-71

Section of Comparative Medicine and Department of Obstetrics, Gynecology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2744-08.2
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http://dx.doi.org/10.1523/JNEUROSCI.2744-08.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865437PMC
October 2008

Megalin mediates the transport of leptin across the blood-CSF barrier.

Neurobiol Aging 2008 Jun 26;29(6):902-12. Epub 2007 Feb 26.

Department of Biochemistry, ICBS, University Federal do Rio Grande de Sul, Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.01.008DOI Listing
June 2008

Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode.

Biol Psychiatry 2007 Jan 7;61(2):142-4. Epub 2006 Aug 7.

Mood Disorders Program, Fundação Faculdade Federal Ciências Medicas de Porto Alegre, Bipolar Disorder Research Program, Espírita Hospital of Porto Alegre, Porto Alegre, Brazil.

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http://dx.doi.org/10.1016/j.biopsych.2006.03.070DOI Listing
January 2007

Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain.

Brain Res 2005 Dec 18;1065(1-2):20-5. Epub 2005 Nov 18.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, 90035-003, Porto Alegre/RS, Brazil.

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http://dx.doi.org/10.1016/j.brainres.2005.09.038DOI Listing
December 2005

Motor impairment induced by oral exposure to methylmercury in adult mice.

Environ Toxicol Pharmacol 2005 Jan;19(1):169-75

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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http://linkinghub.elsevier.com/retrieve/pii/S138266890400133
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http://dx.doi.org/10.1016/j.etap.2004.07.004DOI Listing
January 2005

Guanosine selectively inhibits locomotor stimulation induced by the NMDA antagonist dizocilpine.

Behav Brain Res 2004 Oct;154(2):417-22

Departamento de Bioquímica, ICBS, Universidade Federal do Grande do Sul (UFRGS), Rua Ramiro Barcellos 2600, anexo, 90035003 Porto Alegre, Brazil.

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http://dx.doi.org/10.1016/j.bbr.2004.03.008DOI Listing
October 2004

Increased locomotor response to amphetamine, but not other psychostimulants, in adult mice submitted to a low-protein diet.

Physiol Behav 2004 Oct;83(1):129-33

Departamento de Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

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http://dx.doi.org/10.1016/j.physbeh.2004.08.003DOI Listing
October 2004

Influence of anticoagulants on the measurement of S100B protein in blood.

Clin Biochem 2003 Nov;36(8):629-32

Departamento de Bioquímica, ICBS, UFRGS, Brazil.

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November 2003

Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

Toxicol Lett 2003 Oct;144(3):351-7

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600 Anexo CEP, 90035-003 Porto Alegre, RS, Brazil.

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October 2003

Influence of anticoagulants on the measurement of S100B protein in blood.

Clin Biochem 2003 Oct;36(7):519-22

Departamento de Bioquímica, ICBS, UFRGS, Brazil.

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October 2003

Increase in serum S100B protein level after a swimming race.

Can J Appl Physiol 2003 Oct;28(5):710-6

Dept. de Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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October 2003

Effect of riluzole on MK-801 and amphetamine-induced hyperlocomotion.

Neuropsychobiology 2003 ;48(1):27-30

Laboratório de Neurobiologia Experimental, Departamento de Bioquímica, ICBS, UFRGS, Porto Alegre, Brazil.

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http://dx.doi.org/10.1159/000071825DOI Listing
September 2003