Marcel Wolbers

Marcel Wolbers

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Marcel Wolbers

Marcel Wolbers

Publications by authors named "Marcel Wolbers"

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Immunochemotherapy With Obinutuzumab or Rituximab for Previously Untreated Follicular Lymphoma in the GALLIUM Study: Influence of Chemotherapy on Efficacy and Safety.

J Clin Oncol 2018 08 1;36(23):2395-2404. Epub 2018 Jun 1.

Wolfgang Hiddemann and Roswitha Forstpointner, University Hospital, Ludwig Maximilian University Munich, Munich; Jan Dürig, University Hospital Essen, Essen; Michael Herold, HELIOS-Klinikum Erfurt, Erfurt, Germany; Anna Maria Barbui, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy; Miguel A. Canales, Hospital Universitario la Paz, Madrid, Spain; Paul K. Cannell, Fiona Stanley Hospital, Murdoch, Western Australia; Mark Hertzberg, Prince of Wales Hospital; Judith Trotman, Concord Repatriation General Hospital, University of Sydney, Sydney, New South Wales; John F. Seymour, Royal Melbourne Hospital, and University of Melbourne, Melbourne, Victoria, Australia; Graham P. Collins, Churchill Hospital, Oxford; John Radford, University of Manchester and the Christie National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester; Robert E. Marcus, Kings College Hospital, London, United Kingdom; Magdalena Klanova, Charles University General Hospital, Prague, Czech Republic; Magdalena Klanova, Alis Burciu, Günter Fingerle-Rowson, Marcel Wolbers, and Tina Nielsen, F. Hoffmann-La Roche, Basel, Switzerland; and Kensei Tobinai, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1200/JCO.2017.76.8960DOI Listing
August 2018

Itraconazole or Amphotericin B for Talaromycosis.

N Engl J Med 2017 10;377(14):1403

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam

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http://dx.doi.org/10.1056/NEJMc1709123DOI Listing
October 2017

Smooth semi-nonparametric (SNP) estimation of the cumulative incidence function.

Stat Med 2017 Aug 23;36(18):2921-2934. Epub 2017 May 23.

Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1002/sim.7331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518232PMC
August 2017

A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis.

N Engl J Med 2017 06;376(24):2329-2340

From Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit (T.L., N.T.T., T.P.T., N.T.H., H.B.L., H.T.N., H.F.L.W., J.N.D., J.F., G.T., M.W.), and the Hospital for Tropical Diseases (N.T.K.C., N.L.N.T., N.V.V.C.), Ho Chi Minh City, the National Hospital for Tropical Diseases (N.V.K., N.T.L.) and Bach Mai Hospital (P.T.T.T., D.D.C.), Hanoi, Viet Tiep Hospital, Hai Phong (P.T.H.P., V.H.V.), and Vietnam-Sweden Uong Bi Hospital, Quang Ninh (D.T.H.H., V.V.T.) - all in Vietnam; the Centre for Tropical Medicine and Global Health (T.L., J.N.D., G.T., M.W.), and the Worldwide Antimalarial Resistance Network (L.M.), University of Oxford, Oxford, United Kingdom; the Department of Medical Microbiology, Radboudumc, Nijmegen, the Netherlands (H.F.L.W.); and the Hawaii Center for AIDS, University of Hawaii at Manoa, Honolulu (T.L., C.S.).

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http://dx.doi.org/10.1056/NEJMoa1613306DOI Listing
June 2017

Weighted analysis of composite endpoints with simultaneous inference for flexible weight constraints.

Stat Med 2017 02 26;36(3):442-454. Epub 2016 Oct 26.

Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1002/sim.7147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217097PMC
February 2017

Rapid decline in the susceptibility of Plasmodium falciparum to dihydroartemisinin-piperaquine in the south of Vietnam.

Malar J 2017 01 13;16(1):27. Epub 2017 Jan 13.

Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, 764 Vo Van Kiet Street, Ward 1, District 5, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1186/s12936-017-1680-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237149PMC
January 2017

Association of Microvascular Function and Endothelial Biomarkers With Clinical Outcome in Dengue: An Observational Study.

J Infect Dis 2016 Sep 26;214(5):697-706. Epub 2016 May 26.

Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Hanoi Nuffield Department of Medicine, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/infdis/jiw220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978369PMC
September 2016

Point-of-care C-reactive protein testing to reduce inappropriate use of antibiotics for non-severe acute respiratory infections in Vietnamese primary health care: a randomised controlled trial.

Lancet Glob Health 2016 09 3;4(9):e633-41. Epub 2016 Aug 3.

Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Hanoi, Vietnam; Nuffield Department of Medicine, Centre for Tropical Medicine, University of Oxford, Oxford, UK; Department of Medical Microbiology, Radboudumc, Nijmegen, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(16)30142-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985565PMC
September 2016

Dexamethasone in Cryptococcal Meningitis.

N Engl J Med 2016 07;375(2):189-90

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http://dx.doi.org/10.1056/NEJMc1605205DOI Listing
July 2016

Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial.

Lancet Infect Dis 2016 May 20;16(5):535-545. Epub 2016 Jan 20.

The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford, UK; Department of Zoology, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1016/S1473-3099(15)00530-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835582PMC
May 2016

A Prognostic Model for Development of Profound Shock among Children Presenting with Dengue Shock Syndrome.

PLoS One 2015 6;10(5):e0126134. Epub 2015 May 6.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126134PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422752PMC
April 2016

Clinical implications of reduced susceptibility to fluoroquinolones in paediatric Shigella sonnei and Shigella flexneri infections.

J Antimicrob Chemother 2016 Mar 17;71(3):807-15. Epub 2015 Dec 17.

Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam Centre for Tropical Medicine, Oxford University, Oxford, UK The London School of Hygiene and Tropical Medicine, London, UK

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http://jac.oxfordjournals.org/content/early/2015/12/17/jac.d
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http://www.jac.oxfordjournals.org/lookup/doi/10.1093/jac/dkv
Publisher Site
http://dx.doi.org/10.1093/jac/dkv400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743702PMC
March 2016

Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis.

N Engl J Med 2016 Feb;374(6):542-54

From the Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme Vietnam (J.B., M.W., J.F., L.M., G.T., J.N.D.), Hospital for Tropical Diseases (N.T.K.C., N.V.V.C.), Cho Ray Hospital (T.Q.B., L.P.), Ho Chi Minh City, and the National Hospital for Tropical Diseases (N.V.K.) and Bach Mai Hospital (P.T.T.), Hanoi - all in Vietnam; Nuffield Department of Clinical Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford (J.B., M.W., J.F., L.M., G.T., M.M., D.D., J.N.D.), University College London, London (R.H.), and Liverpool School of Tropical Medicine, Liverpool (D.G.L.) - all in the United Kingdom; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda (F.M.K., A.-B.M.G., A.K.); Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok (W.C.), Ubon Sappasithiprasong Hospital, Ubon (S.S., W.S.), and Udon Thani Hospital, Udon Thani (E.T., S.O.) - all in Thailand; Dignitas International, Zomba (A.K.C., E.M., J.J.O.), and Malawi-Liverpool-Wellcome Trust, Clinical Research Programme (R.H., D.G.L.), and University of Malawi College of Medicine (R.H., J.J.O.), Blantyre - all in Malawi; Sunnybrook Health Sciences Centre, University of Toronto, Toronto (A.K.C.); Cipto Mangunkusumo Hospital (D.I.) and Eijkman Oxford Clinical Research Unit (H.B.) - both in Jakarta, Indonesia; and Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital (M.M., D.D., P.P., S.R.), and University of Health Sciences (M.M.) - both in Vientiane, Laos.

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http://dx.doi.org/10.1056/NEJMoa1509024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778268PMC
February 2016

Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis.

N Engl J Med 2016 Jan;374(2):124-34

From the Oxford University Clinical Research Unit (A.D.H., N.D.B., N.T.H.M., T.T.H.C., N.H.P., T.T.H., N.T.B.Y., D.T.M.H., J.N.D., L.M., T.T.V.T., M.W., G.E.T., J.J.F.), Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease (N.D.B., N.H.D., N.T.N.L., N.H.L., N.N.L., L.T.P., N.N.V., N.Q.H., N.T.B.Y., D.T.M.H.), and Hospital for Tropical Diseases (N.H.P., P.P.L., N.V.V.C.) - all in Ho Chi Minh City, Vietnam; and the Nuffield Department of Medicine, University of Oxford, Oxford (A.D.H., J.N.D., L.M., M.W., G.E.T., J.J.F.), and Liverpool University, Liverpool (M.C.) - both in the United Kingdom.

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http://www.nejm.org/doi/10.1056/NEJMoa1507062
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http://dx.doi.org/10.1056/NEJMoa1507062DOI Listing
January 2016

Second-Line HIV Therapy Outcomes and Determinants of Mortality at the Largest HIV Referral Center in Southern Vietnam.

Medicine (Baltimore) 2015 Oct;94(43):e1715

From the Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit (VPT, MW, NDA, JF, JD, GT, TLE); Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam (VMQ, NVVC); Hawaii Centre for AIDS, University of Hawaii at Manoa, Honolulu, Hawaii (CS, TLE); and Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia (SD).

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http://dx.doi.org/10.1097/MD.0000000000001715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985375PMC
October 2015

Sensitivity and specificity of a novel classifier for the early diagnosis of dengue.

PLoS Negl Trop Dis 2015 Apr 2;9(4):e0003638. Epub 2015 Apr 2.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam; Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia; Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Nossal Institute of Global Health, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pntd.0003638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383489PMC
April 2015

Limitation of the Benefit of Amphotericin-Flucytosine Combination Therapy in Patients With Lower Conscious Level: An Ecological Fallacy?

Open Forum Infect Dis 2015 Apr 14;2(2):ofv069. Epub 2015 May 14.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases , Ho Chi Minh City , Vietnam ; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine , University of Oxford , United Kingdom.

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http://dx.doi.org/10.1093/ofid/ofv069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473111PMC
April 2015

Hemagglutination inhibiting antibodies and protection against seasonal and pandemic influenza infection.

J Infect 2015 Feb 16;70(2):187-96. Epub 2014 Sep 16.

Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Viet Nam; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.jinf.2014.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309889PMC
February 2015

Households as foci for dengue transmission in highly urban Vietnam.

PLoS Negl Trop Dis 2015 Feb 13;9(2):e0003528. Epub 2015 Feb 13.

Oxford University Clinical Research Unit-Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine, University of Oxford, Oxford, United Kingdom; Department of Microbiology and Immunology, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1371/journal.pntd.0003528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332484PMC
February 2015

Sustained use of biogas fuel and blood pressure among women in rural Nepal.

Environ Res 2015 Jan 25;136:343-51. Epub 2014 Nov 25.

Institute for Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universitaet, Munich, Germany.

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http://dx.doi.org/10.1016/j.envres.2014.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271778PMC
January 2015

Competing risks analyses: objectives and approaches.

Eur Heart J 2014 Nov 7;35(42):2936-41. Epub 2014 Apr 7.

Section for Clinical Biometrics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1093/eurheartj/ehu131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223609PMC
November 2014

Corticosteroids for dengue - why don't they work?

PLoS Negl Trop Dis 2013 12;7(12):e2592. Epub 2013 Dec 12.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam ; Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom ; Nossal Institute of Global Health, School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pntd.0002592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861232PMC
July 2014

Concordance for prognostic models with competing risks.

Biostatistics 2014 Jul 2;15(3):526-39. Epub 2014 Feb 2.

Department of Biostatistics, University of Copenhagen, 1014 Copenhagen K, Denmark.

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http://dx.doi.org/10.1093/biostatistics/kxt059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059461PMC
July 2014

Evaluation of GeneXpert MTB/RIF for diagnosis of tuberculous meningitis.

J Clin Microbiol 2014 Jan 6;52(1):226-33. Epub 2013 Nov 6.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1128/JCM.01834-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911435PMC
January 2014

Considerations in the design of clinical trials to test novel entomological approaches to dengue control.

PLoS Negl Trop Dis 2012 29;6(11):e1937. Epub 2012 Nov 29.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam.

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http://dx.doi.org/10.1371/journal.pntd.0001937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510076PMC
April 2013

Combination antifungal therapy for cryptococcal meningitis.

N Engl J Med 2013 Apr;368(14):1291-1302

Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme Vietnam (J.N.D., T.T.H.C., M.W., N.H.M., N.H.P., H.D.N., C.Q.T., L.H.T., V.A.D., T.N.H., P.T.D., S.G.B., T.T.H., J.J.F.), and the Hospital for Tropical Diseases (T.T.H.C., P.P.M., N.T.D., N.H.M., N.H.P., H.D.N., N.D.P., L.V.C., D.X.S., T.P.M.S., N.V.V.C.) - both in Ho Chi Minh City, Vietnam; and the Centre for Tropical Medicine, Oxford University, Oxford (J.N.D., M.W., J.I.C., S.G.B., T.T.H., J.J.F.), and the Liverpool School of Tropical Medicine, Liverpool (D.G.L.) - both in the United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa1110404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978204PMC
April 2013

Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials.

PLoS Negl Trop Dis 2012 27;6(9):e1752. Epub 2012 Sep 27.

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1371/journal.pntd.0001752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459884PMC
January 2013

Influence of antituberculosis drug resistance and Mycobacterium tuberculosis lineage on outcome in HIV-associated tuberculous meningitis.

Antimicrob Agents Chemother 2012 Jun 2;56(6):3074-9. Epub 2012 Apr 2.

Oxford University Clinical Research Unit Vietnam, Wellcome Trust Major Overseas Programme, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1128/AAC.00319-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370761PMC
June 2012

Competing risks and the clinical community: irrelevance or ignorance?

Stat Med 2012 May 23;31(11-12):1089-97. Epub 2011 Sep 23.

Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1002/sim.4384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575691PMC
May 2012

The epidemiology of interpandemic and pandemic influenza in Vietnam, 2007-2010: the Ha Nam household cohort study I.

Am J Epidemiol 2012 May 12;175(10):1062-74. Epub 2012 Mar 12.

Oxford University Clinical Research Unit, National Hospital of Tropical Diseases, 78 Giai Phong Street, Dong Da District, Hanoi, Vietnam.

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http://dx.doi.org/10.1093/aje/kws121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353138PMC
May 2012