Publications by authors named "Marcel E Dinger"

100Publications

Emerging role of non-coding RNAs in response of cancer cells to radiotherapy.

Pathol Res Pract 2020 Dec 28;218:153327. Epub 2020 Dec 28.

Urogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

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December 2020

LncRNAs and miRNAs participate in determination of response of cancer cells to cisplatin.

Exp Mol Pathol 2021 Jan 7:104602. Epub 2021 Jan 7.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:

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January 2021

The critical roles of lncRNAs in the pathogenesis of melanoma.

Exp Mol Pathol 2020 Dec 21;117:104558. Epub 2020 Oct 21.

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

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December 2020

Dysregulation of non-coding RNAs in autoimmune thyroid disease.

Exp Mol Pathol 2020 Dec 8;117:104527. Epub 2020 Sep 8.

Department of Medical genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

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December 2020

Identification of miRNA-mRNA Network in Autism Spectrum Disorder Using a Bioinformatics Method.

J Mol Neurosci 2020 Sep 2. Epub 2020 Sep 2.

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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September 2020

Dysregulation of non-coding RNAs in Rheumatoid arthritis.

Biomed Pharmacother 2020 Oct 8;130:110617. Epub 2020 Aug 8.

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

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October 2020

Emerging roles of non-coding RNAs in the pathogenesis of type 1 diabetes mellitus.

Biomed Pharmacother 2020 Sep 9;129:110509. Epub 2020 Jul 9.

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

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September 2020

Equitable Expanded Carrier Screening Needs Indigenous Clinical and Population Genomic Data.

Am J Hum Genet 2020 08;107(2):175-182

Genetic Services of Western Australia, Department of Health, Government of Western Australia, Perth, WA 6004, Australia; The Western Australian Register of Developmental Anomalies, Department of Health, Government of Western Australia, Perth, WA 6004, Australia; School of Medicine, Division of Paediatrics and Telethon Kids Institute, University of Western Australia, Perth, WA 6009, Australia. Electronic address:

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August 2020

Perspectives on the Role of Non-Coding RNAs in the Regulation of Expression and Function of the Estrogen Receptor.

Cancers (Basel) 2020 Aug 4;12(8). Epub 2020 Aug 4.

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran 19839-63113, Iran.

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August 2020

Exploring the Role of Non-Coding RNAs in the Pathophysiology of Systemic Lupus Erythematosus.

Biomolecules 2020 06 22;10(6). Epub 2020 Jun 22.

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran 1985717443, Iran.

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June 2020

Overcoming challenges and dogmas to understand the functions of pseudogenes.

Nat Rev Genet 2020 03 17;21(3):191-201. Epub 2019 Dec 17.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.

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March 2020

Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer.

Cell Mol Gastroenterol Hepatol 2019 2;7(4):819-839. Epub 2019 Mar 2.

Garvan Institute of Medical Research, Sydney, New South Wales, Australia; School of Medicine, Western Sydney University, Sydney, New South Wales, Australia; Microbiome Research Centre, St George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia. Electronic address:

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January 2020

Lipid Uptake Is an Androgen-Enhanced Lipid Supply Pathway Associated with Prostate Cancer Disease Progression and Bone Metastasis.

Mol Cancer Res 2019 05 26;17(5):1166-1179. Epub 2019 Feb 26.

Australian Prostate Cancer Research Centre, Queensland, Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland, Australia.

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May 2019

Role and practice evolution for genetic counseling in the genomic era: The experience of Australian and UK genetics practitioners.

J Genet Couns 2019 04 15;28(2):378-387. Epub 2018 Dec 15.

Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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April 2019

Seave: a comprehensive web platform for storing and interrogating human genomic variation.

Bioinformatics 2019 01;35(1):122-125

Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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January 2019

Index suffix-prefix overlaps by (w, k)-minimizer to generate long contigs for reads compression.

Bioinformatics 2019 06;35(12):2066-2074

Advanced Analytics Institute, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, Australia.

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June 2019

Response to Brodehl et al.

Genet Med 2019 05 28;21(5):1248-1249. Epub 2018 Sep 28.

Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.

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May 2019

Selection of Antibody Fragments Against Structured DNA by Phage Display.

Methods Mol Biol 2018 ;1827:197-209

Garvan Institute of Medical Research, Sydney, NSW, Australia.

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April 2019

Expanding the spectrum of mutations and novel insights into disease mechanisms.

Mol Genet Metab Rep 2018 Sep 20;16:46-51. Epub 2018 Jul 20.

Department of Neurogenetics, Kolling Institute, Royal North Shore Hospital, St. Leonards, NSW, Australia.

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September 2018

Realizing the significance of noncoding functionality in clinical genomics.

Exp Mol Med 2018 08 7;50(8):97. Epub 2018 Aug 7.

Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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August 2018

Whole Genome Sequencing Improves Outcomes of Genetic Testing in Patients With Hypertrophic Cardiomyopathy.

J Am Coll Cardiol 2018 07;72(4):419-429

Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Sydney, New South Wales, Australia; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia. Electronic address:

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July 2018

I-motif DNA structures are formed in the nuclei of human cells.

Nat Chem 2018 06 23;10(6):631-637. Epub 2018 Apr 23.

Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia.

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June 2018

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

Cell Metab 2018 May 19;27(5):1096-1110.e5. Epub 2018 Apr 19.

Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia; Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia; Faculty of Medicine, St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, NSW 2010, Australia. Electronic address:

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May 2018

A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures.

Cell 2018 02;172(5):924-936.e11

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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February 2018

Universal Alternative Splicing of Noncoding Exons.

Cell Syst 2018 Feb 24;6(2):245-255.e5. Epub 2018 Jan 24.

Garvan Institute of Medical Research, Sydney, NSW, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia; Altius Institute for Biomedical Sciences, Seattle, WA, USA. Electronic address:

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February 2018

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity.

Immunity 2017 12;47(6):1142-1153.e4

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St. Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW 2010, Australia. Electronic address:

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December 2017

NMNAT1 variants cause cone and cone-rod dystrophy.

Eur J Hum Genet 2018 03 28;26(3):428-433. Epub 2017 Nov 28.

Eye Genetics Research, The Children's Hospital at Westmead, Save Sight Institute, Children's Medical Research Institute, University of Sydney, Sydney, NSW, Australia.

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March 2018

Machine learning annotation of human branchpoints.

Bioinformatics 2018 03;34(6):920-927

Genomics and Epigenetics, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.

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March 2018

A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy.

Cell Rep 2017 Oct;21(4):926-933

Pharmacology and Toxicology, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA; Program for Neuroscience, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA. Electronic address:

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October 2017

RNA-seq reveals more consistent reference genes for gene expression studies in human non-melanoma skin cancers.

PeerJ 2017 21;5:e3631. Epub 2017 Aug 21.

Dermatology Research Centre, Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, The University of Queensland, Brisbane, Queensland, Australia.

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August 2017

Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.

BMC Genomics 2017 03 23;18(1):250. Epub 2017 Mar 23.

Division of Genomics and Epigenetics, Garvan Institute of Medical Research, Sydney, Australia.

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March 2017

The regulatory role of long noncoding RNAs in cancer.

Cancer Lett 2017 04 19;391:12-19. Epub 2017 Jan 19.

Children's Cancer Institute Australia for Medical Research, Randwick, Sydney, NSW 2031, Australia; UNSW Centre for Childhood Cancer Research, UNSW Australia, Kensington, Sydney, NSW 2052, Australia. Electronic address:

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April 2017

Computational Approaches for Functional Prediction and Characterisation of Long Noncoding RNAs.

Trends Genet 2016 10 1;32(10):620-637. Epub 2016 Sep 1.

Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, Australia. Electronic address:

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October 2016

Corrigendum: Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity.

Front Neurosci 2016 27;10:354. Epub 2016 Jul 27.

Department of Biomedicine and K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen Bergen, Norway.

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July 2016

Long noncoding RNAs in cancer: mechanisms of action and technological advancements.

Mol Cancer 2016 05 27;15(1):43. Epub 2016 May 27.

Genome Informatics, Genomics & Epigenetics Division, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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May 2016

Endogenous microRNA sponges: evidence and controversy.

Nat Rev Genet 2016 May 4;17(5):272-83. Epub 2016 Apr 4.

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia.

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May 2016

Comparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision making.

Pathology 2016 Apr 9;48(3):261-6. Epub 2016 Mar 9.

Melanoma Institute Australia, North Sydney, NSW, Australia; Discipline of Pathology, Sydney Medical School, The University of Sydney, NSW, Australia; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

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April 2016

Claudin-11 and occludin are major contributors to Sertoli cell tight junction function, in vitro.

Asian J Androl 2016 Jul-Aug;18(4):620-6

Male Fertility Regulation Laboratory, Hudson Institute of Medical Research, Monash Medical Centre, Clayton, Victoria 3168, Australia.

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March 2017

Identification of a novel fusion transcript between human relaxin-1 (RLN1) and human relaxin-2 (RLN2) in prostate cancer.

Mol Cell Endocrinol 2016 Jan 21;420:159-68. Epub 2015 Oct 21.

Institute of Health and Biomedical Innovation, Australian Prostate Cancer Research Centre-Queensland, Queensland University of Technology/Translational Research Institute, Brisbane, QLD, Australia; Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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January 2016

Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity.

Front Neurosci 2015 1;9:351. Epub 2015 Oct 1.

Department of Biomedicine and K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen Bergen, Norway.

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October 2015

Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.

Mol Genet Metab 2015 Nov 14;116(3):178-86. Epub 2015 Aug 14.

Sydney Children's Hospital, High Street Randwick NSW 2031, Australia; University of New South Wales, High Street, Sydney, NSW 2052, Australia; Seals Molecular Genetics, POW Hospital Campus, Barker Street, Randwick, Sydney, NSW 2031, Australia. Electronic address:

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November 2015

The specificity of long noncoding RNA expression.

Biochim Biophys Acta 2016 Jan 19;1859(1):16-22. Epub 2015 Aug 19.

Division of Genomics and Epigenetics, Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Australia. Electronic address:

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January 2016

Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing.

Nat Methods 2015 Apr 9;12(4):339-42. Epub 2015 Mar 9.

1] Garvan Institute of Medical Research, Sydney, Australia. [2] St Vincents Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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April 2015

Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells.

Cell Div 2015 19;10. Epub 2015 Feb 19.

The Kinghorn Cancer Centre and Cancer Research Program, Garvan Institute of Medical Research, Sydney, NSW Australia ; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, Australia.

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March 2015

Genome-wide discovery of human splicing branchpoints.

Genome Res 2015 Feb 5;25(2):290-303. Epub 2015 Jan 5.

Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia; St. Vincent's Clinical School, Faculty of Medicine, UNSW Australia, Sydney, New South Wales 2052, Australia;

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February 2015

lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs.

Nucleic Acids Res 2015 Jan 20;43(Database issue):D168-73. Epub 2014 Oct 20.

Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW 2010, Australia St Vincent's Clinical School, University of New South Wales, Sydney, NSW 2052, Australia

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January 2015

Identification of a dinucleotide signature that discriminates coding from non-coding long RNAs.

Front Genet 2014 9;5:316. Epub 2014 Sep 9.

CNRS UMR7216, Epigenetics and Cell Fate, Université Paris Diderot, Sorbonne Paris Cité Paris, France.

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September 2014

The role of microRNAs and long non-coding RNAs in the pathology, diagnosis, and management of melanoma.

Arch Biochem Biophys 2014 Dec 24;563:60-70. Epub 2014 Jul 24.

Sanford-Burnham Medical Research Institute, Orlando, FL 32827, USA. Electronic address:

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December 2014

The impact of genomics on the future of medicine and health.

Med J Aust 2014 Jul;201(1):17-20

Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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July 2014

Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression.

J Natl Cancer Inst 2014 Jul 6;106(7). Epub 2014 Jun 6.

Affiliations of authors: Children's Cancer Institute Australia for Medical Research, Randwick NSW, Australia (PYL, GMM, AET, MW, BL, BBC, MK, TL); Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy (DE, GM, GP); Kids Cancer Centre, Sydney Children's Hospital, Randwick NSW, Australia (GMM); Department of Pathology and Inflammation and Infection Research Centre, University of New South Wales, Kensington 2052, Australia (PP); Institute of Molecular Medicine, Martin Luther University, ZAMED, Halle, Germany (JLB, SH); School of Medicine and Public Health, Priority Research Centre for Cancer Research, University of Newcastle, Callaghan NSW, Australia (XDZ); Harry Perkins Institute of Medical Research, Centre for Medical Research, University of Western Australia, Nedlands WA, Australia (AF); Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst NSW, Australia (AS); St Vincent's Clinical School, University of New South Wales, Darlinghurst NSW, Australia (AS, JSM, MED); Australian Centre for Nanomedicine, Randwick NSW, Australia (MK); Garvan Institute of Medical Research, Darlinghurst NSW, Australia (AS, JSM, MED); School of Women's & Children's Health, University of New South Wales, Randwick NSW, Australia (TL).

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July 2014

Genomics and personalised whole-of-life healthcare.

Trends Mol Med 2014 Sep 4;20(9):479-86. Epub 2014 May 4.

CSIRO Preventative Health National Research Flagship, Adelaide, SA 5000, Australia.

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September 2014

IL-21 contributes to fatal inflammatory disease in the absence of Foxp3+ T regulatory cells.

J Immunol 2014 Feb 20;192(4):1404-14. Epub 2014 Jan 20.

Department of Immunology, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia;

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February 2014

Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli.

PLoS One 2013 28;8(6):e68306. Epub 2013 Jun 28.

The University of Queensland, Institute for Molecular Bioscience, Brisbane, Australia.

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April 2014

Non-coding RNAs in homeostasis, disease and stress responses: an evolutionary perspective.

Brief Funct Genomics 2013 May;12(3):254-78

The Gurdon Institute, University of Cambridge.

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May 2013

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch.

BMC Genomics 2013 Jan 16;14:15. Epub 2013 Jan 16.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Qld 4072, Australia.

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January 2013

Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation.

PLoS Genet 2012 26;8(7):e1002840. Epub 2012 Jul 26.

Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America.

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November 2012

Identification of novel markers of mouse fetal ovary development.

PLoS One 2012 26;7(7):e41683. Epub 2012 Jul 26.

Division of Molecular Genetics and Development, Institute for Molecular Biosciences, The University of Queensland, Brisbane, Australia.

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November 2012