Publications by authors named "Marc-Henri Stern"

97Publications

Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers.

Oncogene 2020 Oct 14. Epub 2020 Oct 14.

Institut Curie, INSERM U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Equipe labellisée par la Ligue Nationale Contre le Cancer, PSL Research University, Paris, France.

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http://dx.doi.org/10.1038/s41388-020-01507-5DOI Listing
October 2020

Uveal melanoma.

Nat Rev Dis Primers 2020 04 9;6(1):24. Epub 2020 Apr 9.

Nuffield Department of Clinical Neurosciences, University of Oxford, West Wing, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1038/s41572-020-0158-0DOI Listing
April 2020

Clinical Interest of Combining Transcriptomic and Genomic Signatures in High-Grade Serous Ovarian Cancer.

Front Genet 2020 17;11:219. Epub 2020 Mar 17.

Institut Curie, Stress and Cancer Laboratory, Equipe labelisée Ligue Nationale Contre le Cancer, PSL University, Paris, France.

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http://dx.doi.org/10.3389/fgene.2020.00219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089941PMC
March 2020

Germline MBD4 mutations and predisposition to uveal melanoma.

J Natl Cancer Inst 2020 Apr 1. Epub 2020 Apr 1.

Inserm U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Equipe labellisée par la Ligue Nationale Contre le Cancer, Paris, France.

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http://dx.doi.org/10.1093/jnci/djaa047DOI Listing
April 2020

High-Accuracy Determination of Microsatellite Instability Compatible with Liquid Biopsies.

Clin Chem 2020 04;66(4):606-613

Inserm U830, DNA Repair and Uveal Melanoma (D.R.U.M.) team, Equipe labellisée par la Ligue Nationale Contre le Cancer, Institut Curie, Paris, France.

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http://dx.doi.org/10.1093/clinchem/hvaa013DOI Listing
April 2020

Lack of evidence for CDK12 as an ovarian cancer predisposing gene.

Fam Cancer 2020 Jul;19(3):203-209

Inserm U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Equipe Labellisee par la Ligue Nationale Contre le Cancer, Institut Curie, 26 Rue d'Ulm, 75248, Paris, France.

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http://dx.doi.org/10.1007/s10689-020-00169-2DOI Listing
July 2020

[Current advances in immunotherapy in ovarian cancer].

Bull Cancer 2020 Apr 20;107(4):465-473. Epub 2020 Feb 20.

Centre Léon-Bérard, 28, rue Laennec, 69008 Lyon, France.

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http://dx.doi.org/10.1016/j.bulcan.2019.11.015DOI Listing
April 2020

JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL.

Cancers (Basel) 2019 Nov 21;11(12). Epub 2019 Nov 21.

Department I of Internal Medicine, Center for Integrated Oncology (CIO), Aachen-Bonn-Cologne-Duesseldorf, University of Cologne (UoC), 50937 Cologne, Germany.

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http://dx.doi.org/10.3390/cancers11121833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966610PMC
November 2019

[Role of MBD4 in hypermutator phenotype and malignant transformation].

Med Sci (Paris) 2018 Nov 10;34(11):925-927. Epub 2018 Dec 10.

Institut Curie, Université de recherche PSL, Inserm U830, DNA repair and uveal melanoma (D.R.U.M.), Équipe labellisée par la Ligue nationale contre le cancer, Paris, 75248, France - Département de génétique, Institut Curie, Université de recherche PSL, Paris, 75248, France.

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https://www.medecinesciences.org/10.1051/medsci/2018226
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http://dx.doi.org/10.1051/medsci/2018226DOI Listing
November 2018

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide.

J Natl Cancer Inst 2018 12;110(12):1328-1341

QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1093/jnci/djy171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292796PMC
December 2018

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers.

Cell Metab 2019 01 20;29(1):156-173.e10. Epub 2018 Sep 20.

Institut Curie, Stress and Cancer Laboratory, Equipe Labelisée par la Ligue Nationale contre le Cancer, PSL Research University, 26, rue d'Ulm, 75005 Paris, France; Inserm, U830, 26, rue d'Ulm, Paris 75005, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183056
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http://dx.doi.org/10.1016/j.cmet.2018.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331342PMC
January 2019

Clinical potential of circulating tumour DNA in patients receiving anticancer immunotherapy.

Nat Rev Clin Oncol 2018 10;15(10):639-650

Department of Medical Oncology, Institut Curie, PSL Research University, Paris, France.

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http://dx.doi.org/10.1038/s41571-018-0074-3DOI Listing
October 2018

[MBD4 inactivation induces a new mutator phenotype in cancers].

Bull Cancer 2018 Sep 19;105(9):736-737. Epub 2018 Jul 19.

Université de recherche PSL, institut Curie, Inserm U830, DNA repair and uveal melanoma (DRUM), équipe labellisée par la ligue nationale contre le cancer, 75248 Paris, France; Université de recherche PSL, institut Curie, département de génétique, 75248 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00074551183019
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http://dx.doi.org/10.1016/j.bulcan.2018.06.006DOI Listing
September 2018

[Uveal melanoma, a model disease for splicing alterations and oncogenesis].

Med Sci (Paris) 2018 Feb 16;34(2):155-160. Epub 2018 Feb 16.

Inserm U830, Institut Curie, université Paris Sciences et Lettres - PSL Research University, 26, rue d'Ulm, 75248 Cedex Paris, France.

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http://dx.doi.org/10.1051/medsci/20183402013DOI Listing
February 2018

Multiple Hotspot Mutations Scanning by Single Droplet Digital PCR.

Clin Chem 2018 02 9;64(2):317-328. Epub 2017 Nov 9.

Circulating Tumor Biomarkers Laboratory, SiRIC, Translational Research Department, Institut Curie, PSL Research University, Paris, France;

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http://dx.doi.org/10.1373/clinchem.2017.272518DOI Listing
February 2018

ATM Gene Mutation Detection Techniques and Functional Analysis.

Methods Mol Biol 2017 ;1599:25-42

Inserm U830, Institut Curie - Section de Recherche, 26 rue d'Ulm, cedex 5, Paris, 75248, France.

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http://dx.doi.org/10.1007/978-1-4939-6955-5_3DOI Listing
February 2018

Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status.

Nat Med 2016 06;22(6):577-8

Institut Curie, Paris Sciences et Lettres Research University, Paris, France.

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http://dx.doi.org/10.1038/nm.4098DOI Listing
June 2016

Clinical applications of circulating tumor DNA and circulating tumor cells in pancreatic cancer.

Mol Oncol 2016 Mar 22;10(3):481-93. Epub 2016 Jan 22.

Institut Curie, PSL Research University, SiRIC, Laboratory of Circulating Tumor Biomarkers, Paris, France; Institut Curie, PSL Research University, Department of Medical Oncology, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528974PMC
March 2016

Circulating tumor DNA for triple-negative breast cancer diagnosis and treatment decisions.

Expert Rev Mol Diagn 2016 9;16(1):39-50. Epub 2015 Dec 9.

a Institut Curie , PSL Research University , Paris , France.

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http://dx.doi.org/10.1586/14737159.2016.1121100DOI Listing
October 2016

Upcoming translational challenges for uveal melanoma.

Br J Cancer 2015 Nov 27;113(9):1249-53. Epub 2015 Oct 27.

Department of Translational Research, Institut Curie, 26 rue d'Ulm, Paris 75005, France.

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http://dx.doi.org/10.1038/bjc.2015.269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815787PMC
November 2015

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer.

Genome Res 2015 Apr 4;25(4):488-503. Epub 2015 Feb 4.

Centre de Recherche, Institut Curie, 75248 Paris Cedex 05, France; Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3215, Institut Curie, 75248 Paris Cedex 05, France; Institut National de la Santé et de la Recherche Médicale U934, Institut Curie, 75248 Paris Cedex 05, France; Equipe Labellisée Ligue Contre le Cancer, UMR3215, 75248 Paris Cedex 05, France;

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http://dx.doi.org/10.1101/gr.185926.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381521PMC
April 2015

Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types.

Mol Oncol 2015 Apr 26;9(4):783-90. Epub 2014 Dec 26.

Circulating Cancer Biomarkers Lab, SiRIC, Translational Research Department, Institut Curie, Paris, France; Department of Medical Oncology, Institut Curie, Paris and Saint-Cloud, France; University Paris Descartes, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528781PMC
April 2015

Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .

Mod Pathol 2015 Mar 21;28(3):340-51. Epub 2014 Nov 21.

1] Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA [2] Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/modpathol.2014.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523239PMC
March 2015

The pleiotropic movement disorders phenotype of adult ataxia-telangiectasia.

Neurology 2014 Sep 13;83(12):1087-95. Epub 2014 Aug 13.

From INSERM, UMRS 975, CNRS 7225-CRICM (A.M., E.A., S.R.-P., A.D., M.V., D.G.), AP-HP, Fédération de Neurophysiologie Clinique (B.G., T.M.), AP-HP, Département des Maladies du Système Nerveux (B.D., M.V., D.G.), Département de Génétique et Cytogénétique, Unité Fonctionnelle de Génétique Chromosomique (B.B.), and Département de Génétique et Cytogénétique (A.D., M.A.), Hôpital Pitié-Salpêtrière, Paris; Université Pierre et Marie Curie-Paris-6 (A.M., B.G., E.A., S.R.-P., B.D., A.D., M.V., D.G.); AP-HP, Service de Physiologie (Y.A.-B., E.A.), Hôpital Saint-Antoine; INSERM U830 (G.R., M.-H.S., D.S.-L.), Paris; Unité d'Immuno-Hématologie et Rhumatologie Pédiatriques (N.M., A.F.), CEREDIH (French Reference Center for Primary Immunodeficiencies) (N.M., F.S., A.F.), and Service d'Hématologie Adultes (F.S.), Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (APHP); Imagine Institute (N.M., F.S., A.F.), Sorbonne Paris Cité (D.S.-L.), Université Paris Descartes; Département de Neurologie (C.T., M.A.), Hôpital Civil de Strasbourg; Fédération de Médecine Translationnelle de Strasbourg (FMTS) (C.T., M.A.), Université de Strasbourg; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) (C.T., M.K., M.A.), INSERM-U964/CNRS-UMR7104/Université de Strasbourg, Illkirch; Laboratoire de Diagnostic Génétique (M.K.), Nouvel Hôpital Civil, Strasbourg; Laboratoire de Génétique des Maladies Rares (M.K.), INSERM UMR_S 827, Institut Universitaire de Recherche Clinique, Montpellier; and Department of Tumour Biology (M.-H.S., C.D.E., D.S.-L.), Institut Curie, Paris, France.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000079
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http://dx.doi.org/10.1212/WNL.0000000000000794DOI Listing
September 2014

Mutation in TTI2 reveals a role for triple T complex in human brain development.

Hum Mutat 2013 Nov 10;34(11):1472-6. Epub 2013 Sep 10.

INSERM U781, Université Paris Descartes, Sorbonne Paris Cité, Institut IMAGINE, Hôpital Necker-Enfants Malades, Paris, France.

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http://dx.doi.org/10.1002/humu.22399DOI Listing
November 2013

Streamlined ion torrent PGM-based diagnostics: BRCA1 and BRCA2 genes as a model.

Eur J Hum Genet 2014 Apr 14;22(4):535-41. Epub 2013 Aug 14.

1] Service de Génétique Oncologique, Institut Curie, Paris, France [2] INSERM U830, Centre de Recherche de l'Institut Curie, Paris, France [3] Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1038/ejhg.2013.181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953907PMC
April 2014

Detection rate and prognostic value of circulating tumor cells and circulating tumor DNA in metastatic uveal melanoma.

Int J Cancer 2014 Mar 3;134(5):1207-13. Epub 2013 Sep 3.

Department of Medical Oncology, Institut Curie, Paris, France; Laboratory of Circulating Tumor Biomarkers, Institut Curie, Paris, France.

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http://dx.doi.org/10.1002/ijc.28436DOI Listing
March 2014

Loss of heterozygosity at 13q13 and 14q32 predicts BRCA2 inactivation in luminal breast carcinomas.

Int J Cancer 2013 Dec 10;133(12):2834-42. Epub 2013 Jul 10.

Institut Curie, Centre de Recherche, Paris, France; INSERM U830, Paris, France; Department of Tumor Biology, Institut Curie, Paris, France.

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http://dx.doi.org/10.1002/ijc.28315DOI Listing
December 2013

The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCtheta and ERK pathways.

Blood 2007 Dec 10;110(13):4406-16. Epub 2007 Sep 10.

Institut Curie, Centre de Recherche, Paris, France.

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http://dx.doi.org/10.1182/blood-2006-11-059501DOI Listing
December 2007

JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas.

Cancer Cell 2007 Apr;11(4):361-74

Institut Curie, Genetics and Biology of Cancers, 26 rue d'Ulm, 75248 Paris cedex 05, France; INSERM U830, F-75005 Paris, France.

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http://dx.doi.org/10.1016/j.ccr.2007.02.007DOI Listing
April 2007

Structural basis for the co-activation of protein kinase B by T-cell leukemia-1 (TCL1) family proto-oncoproteins.

J Biol Chem 2004 Aug 28;279(34):35890-902. Epub 2004 May 28.

Centre de Biochimie Structurale, UMR 5048 CNRS/UM1-UMR 554 INSERM/UM1, Faculté de Pharmacie, BP14491, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1074/jbc.M400364200DOI Listing
August 2004

Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates.

J Biomol NMR 2004 Feb;28(2):137-55

Centre de Biochimie Structurale, UMR 5048 CNRS/UM1 - UMR 554 INSERM/UM1, Faculté de Pharmacie, BP14491, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1023/B:JNMR.0000013836.62154.c2DOI Listing
February 2004

Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1.

Mol Cell Biol 2002 Mar;22(5):1513-25

Division of Immunology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134690PMC
http://dx.doi.org/10.1128/mcb.22.5.1513-1525.2002DOI Listing
March 2002