Marc-Emmanuel Dumas

A targeted ultra performance liquid chromatography - Tandem mass spectrometric assay for tyrosine and metabolites in urine and plasma: Application to the effects of antibiotics on mice.

Authors:

Marine P M Letertre Antonis Myridakis Luke Whiley Stéphane Camuzeaux Matthew R Lewis Katie E Chappell Annie Thaikkatil Marc-Emmanuel Dumas Jeremy K Nicholson Jonathan R Swann Ian D Wilson

J Chromatogr B Analyt Technol Biomed Life Sci 2020 Dec 22;1164:122511. Epub 2020 Dec 22.

Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, SW7 2AZ, UK. Electronic address:

View Article and Find Full Text PDF

December 2020

Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology.

Nat Commun 2020 Dec 21;11(1):6448. Epub 2020 Dec 21.

Wallenberg Laboratory, Department of Molecular and Clinical Medicine and Sahlgrenska Center for Cardiovascular and Metabolic Research, University of Gothenburg, 413 45, Gothenburg, Sweden.

View Article and Find Full Text PDF

December 2020

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology.

Nat Commun 2020 11 18;11(1):5881. Epub 2020 Nov 18.

Wallenberg Laboratory, Department of Molecular and Clinical Medicine and Sahlgrenska Center for Cardiovascular and Metabolic Research, University of Gothenburg, 413 45, Gothenburg, Sweden.

View Article and Find Full Text PDF

November 2020

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis.

Nature 2020 05 6;581(7808):310-315. Epub 2020 May 6.

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.

View Article and Find Full Text PDF

May 2020

The APOA1bp-SREBF-NOTCH axis is associated with reduced atherosclerosis risk in morbidly obese patients.

Authors:

Jordi Mayneris-Perxachs Josep Puig Rémy Burcelin Marc-Emmanuel Dumas Richard H Barton Lesley Hoyles Massimo Federici José-Manuel Fernández-Real

Clin Nutr 2020 Nov 8;39(11):3408-3418. Epub 2020 Mar 8.

Department of Endocrinology, Diabetes and Nutrition, Hospital of Girona "Dr Josep Trueta", Departament de Ciències Mèdiques, University of Girona, Girona Biomedical Research Institute (IdibGi), Girona, Spain; CIBERobn Pathophysiology of Obesity and Nutrition, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

View Article and Find Full Text PDF

November 2020

Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto-Kakizaki rats improves glucose homeostasis through enhanced FXR signalling.

Authors:

Noémie Péan Aurelie Le Lay Francois Brial Jessica Wasserscheid Claude Rouch Mylène Vincent Antonis Myridakis Lyamine Hedjazi Marc-Emmanuel Dumas Elin Grundberg Mark Lathrop Christophe Magnan Ken Dewar Dominique Gauguier

Diabetologia 2020 06 16;63(6):1223-1235. Epub 2020 Mar 16.

Inserm UMR 1124, Université de Paris, 45 rue des Saint-Pères, 75006, Paris, France.

View Article and Find Full Text PDF

June 2020

The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function.

Authors:

Francois Brial Fawaz Alzaid Kazuhiro Sonomura Yoichiro Kamatani Kelly Meneyrol Aurélie Le Lay Noémie Péan Lyamine Hedjazi Taka-Aki Sato Nicolas Venteclef Christophe Magnan Mark Lathrop Marc-Emmanuel Dumas Fumihiko Matsuda Pierre Zalloua Dominique Gauguier

Cell Rep 2020 02;30(7):2306-2320.e5

Université de Paris, INSERM UMR 1124, 75006 Paris, France; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC H3A 0G1, Canada. Electronic address:

View Article and Find Full Text PDF

February 2020

Diet-induced metabolic changes of the human gut microbiome: importance of short-chain fatty acids, methylamines and indoles.

Authors:

Mohd Badrin Hanizam Abdul Rahim Julien Chilloux Laura Martinez-Gili Ana L Neves Antonis Myridakis Nigel Gooderham Marc-Emmanuel Dumas

Acta Diabetol 2019 May 22;56(5):493-500. Epub 2019 Mar 22.

Division of Systems and Digestive Medicine, Department of Surgery and Cancer, Imperial College London, Exhibition Road, London, SW7 2AZ, UK.

View Article and Find Full Text PDF

May 2019

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment.

Authors:

Francois Brial Aurélie Le Lay Lyamine Hedjazi Tsz Tsang Jane F Fearnside Georg W Otto Fawaz Alzaid Steven P Wilder Nicolas Venteclef Jean-Baptiste Cazier Jeremy K Nicholson Chris Day Alastair D Burt Ivo G Gut Mark Lathrop Marc-Emmanuel Dumas Dominique Gauguier

Sci Rep 2019 03 6;9(1):3656. Epub 2019 Mar 6.

Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France.

View Article and Find Full Text PDF

March 2019

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity.

Front Physiol 2018 5;9:1958. Epub 2019 Feb 5.

Sorbonne University, French National Institute for Health and Medical Research, NutriOmics Unit, Institute of Cardiometabolism and Nutrition, Paris, France.

View Article and Find Full Text PDF

February 2019

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol.

Authors:

Pierre Zalloua Hanane Kadar Essa Hariri Layal Abi Farraj Francois Brial Lyamine Hedjazi Aurelie Le Lay Alexandre Colleu Justine Dubus David Touboul Fumihiko Matsuda Mark Lathrop Jeremy K Nicholson Marc-Emmanuel Dumas Dominique Gauguier

Lipids Health Dis 2019 Feb 2;18(1):38. Epub 2019 Feb 2.

University Paris Descartes, 15 rue de l'Ecole de Médecine, 75006, Paris, France.

View Article and Find Full Text PDF

February 2019

The translational regulator FMRP controls lipid and glucose metabolism in mice and humans.

Authors:

Antoine Leboucher Didier F Pisani Laura Martinez-Gili Julien Chilloux Patricia Bermudez-Martin Anke Van Dijck Tariq Ganief Boris Macek Jérôme A J Becker Julie Le Merrer R Frank Kooy Ez-Zoubir Amri Edouard W Khandjian Marc-Emmanuel Dumas Laetitia Davidovic

Mol Metab 2019 03 14;21:22-35. Epub 2019 Jan 14.

Université Côte d'Azur, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France. Electronic address:

View Article and Find Full Text PDF

March 2019

pJRES Binning Algorithm (JBA): a new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra.

Authors:

Andrea Rodriguez-Martinez Rafael Ayala Joram M Posma Nikita Harvey Beatriz Jiménez Kazuhiro Sonomura Taka-Aki Sato Fumihiko Matsuda Pierre Zalloua Dominique Gauguier Jeremy K Nicholson Marc-Emmanuel Dumas

Bioinformatics 2019 06;35(11):1916-1922

Division of Integrative Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Imperial College London, London, UK.

View Article and Find Full Text PDF

June 2019

Implication of gut microbiota metabolites in cardiovascular and metabolic diseases.

Authors:

Francois Brial Aurélie Le Lay Marc-Emmanuel Dumas Dominique Gauguier

Cell Mol Life Sci 2018 Nov 12;75(21):3977-3990. Epub 2018 Aug 12.

Sorbonne University, University Paris Descartes, INSERM UMR_S1138, Cordeliers Research Centre, 15 rue de l'Ecole de Médecine, 75006, Paris, France.

View Article and Find Full Text PDF

November 2018

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Nat Med 2018 Oct;24(10):1628

Division of Integrative Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Imperial College London, London, UK.

View Article and Find Full Text PDF

October 2018

Exploring the Genetic Landscape of Metabolic Phenotypes with MetaboSignal.

Authors:

Andrea Rodriguez-Martinez Rafael Ayala Joram M Posma Marc-Emmanuel Dumas

Curr Protoc Bioinformatics 2018 03;61(1):14.14.1-14.14.13

Section of Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, South Kensington Campus, Imperial College London, London, United Kingdom.

View Article and Find Full Text PDF

March 2018

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Nat Med 2018 07 25;24(7):1070-1080. Epub 2018 Jun 25.

Division of Integrative Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Imperial College London, London, UK.

View Article and Find Full Text PDF

July 2018

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota.

Authors:

Lesley Hoyles Maria L Jiménez-Pranteda Julien Chilloux Francois Brial Antonis Myridakis Thomas Aranias Christophe Magnan Glenn R Gibson Jeremy D Sanderson Jeremy K Nicholson Dominique Gauguier Anne L McCartney Marc-Emmanuel Dumas

Microbiome 2018 04 20;6(1):73. Epub 2018 Apr 20.

Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Exhibition Road, London, SW7 2AZ, UK.

View Article and Find Full Text PDF

April 2018

Gut Microbiota Interacts with Markers of Adipose Tissue Browning, Insulin Action and Plasma Acetate in Morbid Obesity.

Authors:

José María Moreno-Navarrete Matteo Serino Vincent Blasco-Baque Vincent Azalbert Richard H Barton Marina Cardellini Jèssica Latorre Francisco Ortega Mònica Sabater-Masdeu Rémy Burcelin Marc-Emmanuel Dumas Wifredo Ricart Massimo Federici José Manuel Fernández-Real

Mol Nutr Food Res 2018 02 29;62(3). Epub 2017 Dec 29.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

View Article and Find Full Text PDF

February 2018

MWASTools: an R/bioconductor package for metabolome-wide association studies.

Authors:

Andrea Rodriguez-Martinez Joram M Posma Rafael Ayala Ana L Neves Maryam Anwar Enrico Petretto Costanza Emanueli Dominique Gauguier Jeremy K Nicholson Marc-Emmanuel Dumas

Bioinformatics 2018 03;34(5):890-892

Department of Surgery and Cancer, Computational and Systems Medicine, Imperial College London, UK.

View Article and Find Full Text PDF

March 2018

Publications by authors named "Marc-Emmanuel Dumas"

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors: