Marc Vidal

Marc Vidal

UNVERIFIED PROFILE

Are you Marc Vidal?   Register this Author

Register author
Marc Vidal

Marc Vidal

Publications by authors named "Marc Vidal"

Are you Marc Vidal?   Register this Author

100Publications

3588Reads

40Profile Views

A genome-wide positioning systems network algorithm for in silico drug repurposing.

Nat Commun 2019 Aug 2;10(1):3476. Epub 2019 Aug 2.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-10744-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677722PMC
August 2019

Global Analysis of Intercellular Homeodomain Protein Transfer.

Cell Rep 2019 Jul;28(3):712-722.e3

Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea; KAIST Institute of BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.06.056DOI Listing
July 2019

Protein Interactomics by Two-Hybrid Methods.

Methods Mol Biol 2018 ;1794:1-14

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-7871-7_1DOI Listing
February 2019

APID database: redefining protein-protein interaction experimental evidences and binary interactomes.

Database (Oxford) 2019 01 1;2019. Epub 2019 Jan 1.

Cancer Research Center (CiC-IBMCC, CSIC/USAL/IBSAL), Consejo Superior de Investigaciones Científicas and University of Salamanca, Salamanca, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/database/baz005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354026PMC
January 2019

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target.

Genome Res 2017 09 8;27(9):1487-1500. Epub 2017 Jun 8.

Department of Pharmacology, Brain Science and Engineering Institute, and Department of Biomedical Sciences, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University School of Medicine, Daegu, 41944, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.211649.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580709PMC
September 2017

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing.

PLoS Comput Biol 2017 Aug 28;13(8):e1005717. Epub 2017 Aug 28.

Department of Bioengineering, McGill University, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1005717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591010PMC
August 2017

Proteome-Scale Human Interactomics.

Trends Biochem Sci 2017 05 8;42(5):342-354. Epub 2017 Mar 8.

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tibs.2017.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409865PMC
May 2017

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits.

Am J Hum Genet 2017 Apr 9;100(4):571-580. Epub 2017 Mar 9.

The Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2017.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384035PMC
April 2017

In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.

Cell Syst 2017 02 25;4(2):242-250.e4. Epub 2017 Jan 25.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cels.2017.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578869PMC
February 2017

HSP90 Shapes the Consequences of Human Genetic Variation.

Cell 2017 Feb 16;168(5):856-866.e12. Epub 2017 Feb 16.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Howard Hughes Medical Institute, Cambridge, MA 02139, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325763PMC
February 2017

Playing Hide-and-Seek with Yeast.

Authors:
Marc Vidal

Cell 2016 Aug;166(5):1069-1073

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2016.08.018DOI Listing
August 2016

Mapping transcription factor interactome networks using HaloTag protein arrays.

Proc Natl Acad Sci U S A 2016 07 29;113(29):E4238-47. Epub 2016 Jun 29.

Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037; Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1603229113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961138PMC
July 2016

An extended set of yeast-based functional assays accurately identifies human disease mutations.

Genome Res 2016 05 14;26(5):670-80. Epub 2016 Mar 14.

Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada; Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3E1, Canada; Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario M5G 1X5, Canada; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA; Canadian Institute for Advanced Research, Toronto, Ontario, M5G 1Z8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.192526.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864455PMC
May 2016

How much of the human protein interactome remains to be mapped?

Authors:
Marc Vidal

Sci Signal 2016 05 10;9(427):eg7. Epub 2016 May 10.

Marc Vidal, Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA, and Department of Genetics, Harvard Medical School, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aaf6030DOI Listing
May 2016

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

Mol Syst Biol 2016 Apr 22;12(4):863. Epub 2016 Apr 22.

Donnelly Centre, University of Toronto, Toronto, ON, Canada Lunenfeld-Tanenbaum Research Institute Mt. Sinai Hospital, Toronto, ON, Canada Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA Canadian Institute for Advanced Research, Toronto, ON, Canada Department of Computer Science, University of Toronto, Toronto, Ontario, Canada

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848762PMC
http://dx.doi.org/10.15252/msb.20156660DOI Listing
April 2016

Network-based in silico drug efficacy screening.

Nat Commun 2016 Feb 1;7:10331. Epub 2016 Feb 1.

Center for Complex Networks Research (CCNR) and Department of Physics, Northeastern University, 177 Huntington Avenue, 11th floor, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms10331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740350PMC
February 2016

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Cell 2016 Feb;164(4):805-17

Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science (CEGS), Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2016.01.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882190PMC
February 2016

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy.

Cancer Discov 2016 Jan 6;6(1):45-58. Epub 2015 Nov 6.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-15-0341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775099PMC
January 2016

Global Edgetic Rewiring in Cancer Networks.

Cell Syst 2015 Oct 28;1(4):251-3. Epub 2015 Oct 28.

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cels.2015.10.006DOI Listing
October 2015

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.

Hum Mol Genet 2015 Jun 12;24(11):3005-20. Epub 2015 Jan 12.

Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA Department of Theoretical Physics, Budapest University of Technology and Economics, H1111, Budapest, Hungary Center for Network Science, Central European University, Nador u. 9, 1051 Budapest, Hungary

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddv001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447811PMC
June 2015

Human gene-centered transcription factor networks for enhancers and disease variants.

Cell 2015 Apr;161(3):661-673

Program in Systems Biology and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Cancer Biology, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2015.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409666PMC
April 2015

Protein domain-level landscape of cancer-type-specific somatic mutations.

PLoS Comput Biol 2015 Mar 20;11(3):e1004147. Epub 2015 Mar 20.

Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America; Canadian Institute for Advanced Research, Toronto, Ontario, Canada; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1004147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368709PMC
March 2015

Selecting causal genes from genome-wide association studies via functionally coherent subnetworks.

Nat Methods 2015 Feb 22;12(2):154-9. Epub 2014 Dec 22.

1] Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. [2] Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. [3] Department of Computer Science, University of Toronto, Toronto, Ontario, Canada. [4] Center for Cancer Systems Biology (CCSB), Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [5] Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. [6] Canadian Institute for Advanced Research, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nmeth.3215
Publisher Site
http://dx.doi.org/10.1038/nmeth.3215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480866PMC
February 2015

Disease networks. Uncovering disease-disease relationships through the incomplete interactome.

Science 2015 Feb;347(6224):1257601

Center for Complex Networks Research and Department of Physics, Northeastern University, 110 Forsyth Street, 111 Dana Research Center, Boston, MA 02115, USA. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. Center for Network Science, Central European University, Nador u. 9, 1051 Budapest, Hungary. Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1257601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435741PMC
February 2015

The yeast two-hybrid assay: still finding connections after 25 years.

Nat Methods 2014 Dec;11(12):1203-6

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
December 2014

Multiplex single-molecule interaction profiling of DNA-barcoded proteins.

Nature 2014 Nov 21;515(7528):554-7. Epub 2014 Sep 21.

1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246050PMC
November 2014

A proteome-scale map of the human interactome network.

Cell 2014 Nov;159(5):1212-1226

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://llama.mshri.on.ca/publications/Rolland_Cell_2014.pdf
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S009286741401422
Publisher Site
http://dx.doi.org/10.1016/j.cell.2014.10.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266588PMC
November 2014

A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease.

Cell Rep 2014 Nov 23;9(3):1135-50. Epub 2014 Oct 23.

Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.09.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255334PMC
November 2014

Molecular parameters and transmembrane transport mechanism of imidazolium-functionalized binols.

Chemistry 2014 Aug 7;20(32):9998-10004. Epub 2014 Jul 7.

Departement de Chimie, Université de Montréal, C. P. 6128 Succursale Centre-Ville, Montréal, Québec, H3C 3J7 (Canada), Fax: (+1) 514-343-7586.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201402602DOI Listing
August 2014

Systematic identification of pathological lamin A interactors.

Mol Biol Cell 2014 May 12;25(9):1493-510. Epub 2014 Mar 12.

National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215 Department of Genetics, Harvard Medical School, Boston, MA 02215.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E14-02-0733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004598PMC
May 2014

Edgotype: a fundamental link between genotype and phenotype.

Curr Opin Genet Dev 2013 Dec 26;23(6):649-57. Epub 2013 Nov 26.

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2013.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902775PMC
December 2013

Mycobacterium tuberculosis type VII secreted effector EsxH targets host ESCRT to impair trafficking.

PLoS Pathog 2013 Oct 31;9(10):e1003734. Epub 2013 Oct 31.

Division of Infectious Diseases, Department of Medicine, Department of Pathology and Department of Microbiology, New York University School of Medicine, New York, New York, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1003734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814348PMC
October 2013

Protein interactions of the transcription factor Hoxa1.

BMC Dev Biol 2012 Oct 22;12:29. Epub 2012 Oct 22.

Molecular and Cellular Animal Embryology group, Life Sciences Institute (ISV), Université Catholique de Louvain, Louvain-la-Neuve, 1348, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-213X-12-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514159PMC
October 2012

CKIP-1 regulates mammalian and zebrafish myoblast fusion.

J Cell Sci 2012 Aug 2;125(Pt 16):3790-800. Epub 2012 May 2.

Equipe Différenciation Neuromusculaire, Laboratoire de Biologie Moléculaire de la Cellule, CNRS UMR 5239/ENS Lyon, Université de Lyon, IFR128 Biosciences Lyon-Gerland, 46 Allée d'Italie, 69364 LYON cedex 07, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.101048DOI Listing
August 2012

Protein-protein interactions and networks: forward and reverse edgetics.

Methods Mol Biol 2011 ;759:197-213

Department of Cancer Biology, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-61779-173-4_12DOI Listing
December 2011

A molecular chalice with hydrophobic walls and a hydrophilic rim: self-assembly and complexation properties.

Chem Commun (Camb) 2011 Dec 2;47(48):12834-6. Epub 2011 Nov 2.

Department of Chemistry, Université de Montréal, 2900 Edouard Montpetit CP 6128 Succursalle Centre-ville, Montréal, Québec, Canada H3C3J7.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c1cc15125hDOI Listing
December 2011

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

Authors:
Christopher A Maxwell Javier Benítez Laia Gómez-Baldó Ana Osorio Núria Bonifaci Ricardo Fernández-Ramires Sylvain V Costes Elisabet Guinó Helen Chen Gareth J R Evans Pooja Mohan Isabel Català Anna Petit Helena Aguilar Alberto Villanueva Alvaro Aytes Jordi Serra-Musach Gad Rennert Flavio Lejbkowicz Paolo Peterlongo Siranoush Manoukian Bernard Peissel Carla B Ripamonti Bernardo Bonanni Alessandra Viel Anna Allavena Loris Bernard Paolo Radice Eitan Friedman Bella Kaufman Yael Laitman Maya Dubrovsky Roni Milgrom Anna Jakubowska Cezary Cybulski Bohdan Gorski Katarzyna Jaworska Katarzyna Durda Grzegorz Sukiennicki Jan Lubiński Yin Yao Shugart Susan M Domchek Richard Letrero Barbara L Weber Frans B L Hogervorst Matti A Rookus J Margriet Collee Peter Devilee Marjolijn J Ligtenberg Rob B van der Luijt Cora M Aalfs Quinten Waisfisz Juul Wijnen Cornelis E P van Roozendaal Douglas F Easton Susan Peock Margaret Cook Clare Oliver Debra Frost Patricia Harrington D Gareth Evans Fiona Lalloo Rosalind Eeles Louise Izatt Carol Chu Diana Eccles Fiona Douglas Carole Brewer Heli Nevanlinna Tuomas Heikkinen Fergus J Couch Noralane M Lindor Xianshu Wang Andrew K Godwin Maria A Caligo Grazia Lombardi Niklas Loman Per Karlsson Hans Ehrencrona Anna von Wachenfeldt Rosa Bjork Barkardottir Ute Hamann Muhammad U Rashid Adriana Lasa Trinidad Caldés Raquel Andrés Michael Schmitt Volker Assmann Kristen Stevens Kenneth Offit João Curado Hagen Tilgner Roderic Guigó Gemma Aiza Joan Brunet Joan Castellsagué Griselda Martrat Ander Urruticoechea Ignacio Blanco Laima Tihomirova David E Goldgar Saundra Buys Esther M John Alexander Miron Melissa Southey Mary B Daly Rita K Schmutzler Barbara Wappenschmidt Alfons Meindl Norbert Arnold Helmut Deissler Raymonda Varon-Mateeva Christian Sutter Dieter Niederacher Evgeny Imyamitov Olga M Sinilnikova Dominique Stoppa-Lyonne Sylvie Mazoyer Carole Verny-Pierre Laurent Castera Antoine de Pauw Yves-Jean Bignon Nancy Uhrhammer Jean-Philippe Peyrat Philippe Vennin Sandra Fert Ferrer Marie-Agnès Collonge-Rame Isabelle Mortemousque Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Sue Healey Mary Helen Barcellos-Hoff Marc Vidal Stephen B Gruber Conxi Lázaro Gabriel Capellá Lesley McGuffog Katherine L Nathanson Antonis C Antoniou Georgia Chenevix-Trench Markus C Fleisch Víctor Moreno Miguel Angel Pujana

PLoS Biol 2011 Nov 15;9(11):e1001199. Epub 2011 Nov 15.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute-IDIBELL, L'Hospitalet, Catalonia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.1001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217025PMC
November 2011

Interactome networks and human disease.

Cell 2011 Mar;144(6):986-98

Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2011.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102045PMC
March 2011

High-quality binary interactome mapping.

Methods Enzymol 2010 1;470:281-315. Epub 2010 Mar 1.

Center for Cancer Systems Biology (CCSB), Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0076-6879(10)70012-4DOI Listing
January 2011

A global protein-lipid interactome map.

Mol Syst Biol 2010 Nov;6:443

Center for Cancer Systems Biology, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/msb.2010.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010114PMC
November 2010

Ten years of genetics and genomics: what have we achieved and where are we heading?

Nat Rev Genet 2010 10 7;11(10):723-33. Epub 2010 Sep 7.

INSERM U/CNRS UMR, Institut Curie - Centre de Recherche, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrg2878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004366PMC
October 2010

An antibiotic selection marker for nematode transgenesis.

Nat Methods 2010 Sep 22;7(9):721-3. Epub 2010 Aug 22.

Genome Regulation and Evolution, INSERM U869, Institut Européen de Chimie et Biologie, Pessac, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.1494DOI Listing
September 2010

RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.

PLoS Genet 2010 Aug 5;6(8). Epub 2010 Aug 5.

Joslin Diabetes Center, Harvard Stem Cell Institute, and Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1001048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916858PMC
August 2010

A genome-wide gene function prediction resource for Drosophila melanogaster.

PLoS One 2010 Aug 12;5(8):e12139. Epub 2010 Aug 12.

Department of Cancer Biology, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012139PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920829PMC
August 2010

Systems biology of microorganisms.

Curr Opin Microbiol 2010 Jun 29;13(3):335-6. Epub 2010 Apr 29.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mib.2010.04.005DOI Listing
June 2010

[Systems biology: from yesterday's concepts to tomorrow's discoveries].

Med Sci (Paris) 2009 Jun-Jul;25(6-7):578-84

Center for cancer systems biology, Department of cancer biology, Dana-Farber Cancer Institute, 1, Jimmy Fund Way, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/2009256-7578DOI Listing
January 2010

Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome.

Genome Res 2009 Dec 2;19(12):2334-42. Epub 2009 Oct 2.

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.098640.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792173PMC
December 2009

A unifying view of 21st century systems biology.

Authors:
Marc Vidal

FEBS Lett 2009 Dec;583(24):3891-4

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2009.11.024DOI Listing
December 2009

'Edgetic' perturbation of a C. elegans BCL2 ortholog.

Nat Methods 2009 Nov 25;6(11):843-9. Epub 2009 Oct 25.

Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.1394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865203PMC
November 2009

Shifted Transversal Design smart-pooling for high coverage interactome mapping.

Genome Res 2009 Jul 15;19(7):1262-9. Epub 2009 May 15.

Banting and Best Department of Medical Research and Department of Molecular Genetics, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.090019.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704426PMC
July 2009

NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha.

Nat Cell Biol 2009 Mar 15;11(3):269-77. Epub 2009 Feb 15.

Developmental Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ncb1834
Publisher Site
http://dx.doi.org/10.1038/ncb1834DOI Listing
March 2009

Array MAPPIT: high-throughput interactome analysis in mammalian cells.

J Proteome Res 2009 Feb;8(2):877-86

Department of Medical Protein Research, VIB, A. Baertsoenkaai 3, 9000 Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr8005167DOI Listing
February 2009