Marc P Bonaca

Marc P Bonaca

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Marc P Bonaca

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Efficacy and safety of more potent antiplatelet therapy with vorapaxar in patients with impaired renal function.

J Thromb Thrombolysis 2019 Apr;47(3):353-360

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Rd., Suite 7022, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s11239-018-1779-yDOI Listing
April 2019

Vorapaxar for secondary prevention in the elderly with peripheral artery disease: Insights from the TRA 2°P-TIMI 50 trial.

Vasc Med 2019 04 14;24(2):159-161. Epub 2019 Mar 14.

2 TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/1358863X19826681DOI Listing
April 2019

Prognostic role of GDF-15 across the spectrum of clinical risk in patients with NSTE-ACS.

Clin Chem Lab Med 2019 Feb 2. Epub 2019 Feb 2.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1515/cclm-2018-1081DOI Listing
February 2019

Prevalence and Outcomes of Polyvascular (Coronary, Peripheral, or Cerebrovascular) Disease in Patients With Diabetes Mellitus (From the SAVOR-TIMI 53 Trial).

Am J Cardiol 2019 Jan 26;123(1):145-152. Epub 2018 Sep 26.

TIMI Study Group, Boston, Massachusetts; Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2018.09.014DOI Listing
January 2019

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.

N Engl J Med 2019 01 10;380(4):347-357. Epub 2018 Nov 10.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital (S.D.W., M.P.B., T.A.Z., J.F.K., S.A.M., D.L.B., C.T.R., M.S.S.), and the Cardiology Division, Massachusetts General Hospital (M.G.S.) - both in Boston; the Diabetes Unit, Hadassah Hebrew University Hospital, Jerusalem (I.R., O.M., A.C.); the Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (E.T.K.); Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.); the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (D.K.M.); Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom (J.P.H.W.); and AstraZeneca Gothenburg, Mölndal, Sweden (I.A.M.G.-N., M.F., P.A.J., A.-M.L.).

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http://dx.doi.org/10.1056/NEJMoa1812389DOI Listing
January 2019

Lorcaserin and Renal Outcomes in Obese and Overweight Patients in the CAMELLIA-TIMI 61 Trial.

Circulation 2019 Jan;139(3):366-375

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (B.M.S., E.A.B., A.Q., S.A.M., K.I., M.P.B., C.T.R., M.S.S., S.D.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038341DOI Listing
January 2019

Polyvascular disease, type 2 diabetes, and long-term vascular risk: a secondary analysis of the IMPROVE-IT trial.

Lancet Diabetes Endocrinol 2018 12 2;6(12):934-943. Epub 2018 Nov 2.

Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587183029
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http://dx.doi.org/10.1016/S2213-8587(18)30290-0DOI Listing
December 2018

Pathology of Arterial Disease in Limb Loss: The Clot Thickens.

J Am Coll Cardiol 2018 Oct;72(18):2164-2165

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/MarcBonaca.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183823
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http://dx.doi.org/10.1016/j.jacc.2018.08.2145DOI Listing
October 2018

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients.

N Engl J Med 2018 09 26;379(12):1107-1117. Epub 2018 Aug 26.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston (E.A.B., S.D.W., J.K., K.I., A.Q., M.P.B., C.T.R., M.S.S., B.M.S.); the Cardiovascular Division, University of Texas Southwestern Medical Center, Dallas (D.K.M.); the Section of Endocrinology, Yale School of Medicine, New Haven, CT (S.E.I.); the Department of Medicine, University of Minnesota, Minneapolis (C.L.F.); the Partners Clinical Research Centre, Nassau, Bahamas (C.B.); the Department of Cardiology, Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland (A.B.); Cardiolink Clinical Trials, Monterrey, Mexico (A.G.-C.); McMaster University, Brampton, ON (M.G.), and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.) - both in Canada; MedStar Health Research Institute, Hyattsville, MD (N.J.W.); the Cardiology Department, Auckland City Hospital, Auckland, New Zealand (H.D.W.); Eisai, Woodcliff Lake, NJ (T.P., B.F., W.M., C.P., S.D.); National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (A.C.K.); and the Translational Research Institute for Metabolism and Diabetes, Florida Hospital and the Sanford-Burnham Institute, Winter Park (S.R.S.).

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http://dx.doi.org/10.1056/NEJMoa1808721DOI Listing
September 2018

Polyvascular disease and risk: When two is not better than one.

Authors:
Marc P Bonaca

Vasc Med 2018 Sep 20:1358863X18796936. Epub 2018 Sep 20.

TIMI Study Group, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA.

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http://journals.sagepub.com/doi/10.1177/1358863X18796936
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http://dx.doi.org/10.1177/1358863X18796936DOI Listing
September 2018

DECLARE-TIMI 58: Participants' baseline characteristics.

Diabetes Obes Metab 2018 05 14;20(5):1102-1110. Epub 2018 Feb 14.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1111/dom.13217DOI Listing
May 2018

Rationale and design for the Vascular Outcomes study of ASA along with rivaroxaban in endovascular or surgical limb revascularization for peripheral artery disease (VOYAGER PAD).

Am Heart J 2018 05 3;199:83-91. Epub 2018 Feb 3.

CPC Clinical Research, Aurora, CO; University of Colorado School of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2018.01.011DOI Listing
May 2018

Antithrombotic Therapy and Major Adverse Limb Events in Peripheral Artery Disease: A Step Forward.

J Am Coll Cardiol 2018 May;71(20):2316-2318

Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

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http://dx.doi.org/10.1016/j.jacc.2018.04.001DOI Listing
May 2018

Sodium Glucose Cotransporter 2 Inhibitors and Amputation Risk: Achilles' Heel or Opportunity for Discovery?

Circulation 2018 04;137(14):1460-1462

Cardiovascular Division, Vanderbilt University, Nashville, TN (J.A.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.032745DOI Listing
April 2018

Frequency, Predictors, and Impact of Combined Antiplatelet Therapy on Venous Thromboembolism in Patients With Symptomatic Atherosclerosis.

Circulation 2018 02 30;137(7):684-692. Epub 2017 Oct 30.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (I.C., D.A.M., D.L.B., B.S.S., E.L.G., E.B., M.S.S., M.P.B.)

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.031062DOI Listing
February 2018

Ticagrelor for Secondary Prevention of Atherothrombotic Events in Patients With Multivessel Coronary Disease.

J Am Coll Cardiol 2018 Feb;71(5):489-496

Department of Cardiology, Noordwest Ziekenhuisgroep, Alkmaar and Dutch Network for Cardiovascular Research (WCN), the Netherlands; Department of Cardiology, CWZ Hospital, Nijmegen, the Netherland.

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http://dx.doi.org/10.1016/j.jacc.2017.11.050DOI Listing
February 2018

Time for a New Strategy for High-Sensitivity Troponin in the Emergency Department.

Authors:
Marc P Bonaca

J Am Coll Cardiol 2017 Oct;70(18):2237-2239

TIMI Study Group, Brigham and Women's Hospital, Cardiovascular Division, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.09.021DOI Listing
October 2017

Baseline adiponectin concentration and clinical outcomes among patients with diabetes and recent acute coronary syndrome in the EXAMINE trial.

Diabetes Obes Metab 2017 07 17;19(7):962-969. Epub 2017 Mar 17.

TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1111/dom.12905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765757PMC
July 2017

Utility of multimodality imaging in myopericarditis with aortitis.

J Nucl Cardiol 2017 06 12;24(3):1103-1106. Epub 2016 May 12.

Noninvasive Cardiovascular Imaging, Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s12350-016-0530-3DOI Listing
June 2017

Consistent platelet inhibition with ticagrelor 60 mg twice-daily following myocardial infarction regardless of diabetes status.

Thromb Haemost 2017 05 16;117(5):940-947. Epub 2017 Mar 16.

Prof. Robert F. Storey, MD DM FESC, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK, E-mail:

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http://dx.doi.org/10.1160/TH16-09-0703DOI Listing
May 2017

Vorapaxar in patients with coronary artery bypass grafting: Findings from the TRA 2°P-TIMI 50 trial.

Eur Heart J Acute Cardiovasc Care 2017 Mar 20;6(2):164-172. Epub 2016 Sep 20.

2 TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, USA.

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http://dx.doi.org/10.1177/2048872616644910DOI Listing
March 2017

Antiplatelet Therapy for Secondary Prevention After Acute Myocardial Infarction.

Interv Cardiol Clin 2017 01;6(1):119-129

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.iccl.2016.08.008DOI Listing
January 2017

Prasugrel Versus Ticagrelor: Uncertainty Remains.

Circulation 2016 11;134(21):1613-1616

From TIMI Study Group, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025113DOI Listing
November 2016

Recurrent Aortic Dissection: Observations From the International Registry of Aortic Dissection.

Circulation 2016 Oct 1;134(14):1013-1024. Epub 2016 Sep 1.

From Thoracic Aortic Center (E.M.I., M.A., M.E.L.), Cardiology Division, Department of Medicine (E.M.I., M.E.L.), Cardiovascular Research Center (M.A., M.E.L.), and Pediatric Cardiology Division, Department of Pediatrics (M.E.L.), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Brigham and Women's Hospital, Cardiology Division, Boston, MA (M.P.B.); Cardiac Surgery Department, University Hospital S. Orsola, Bologna, Italy (M.D.E.); Cardiovascular Center (J.F., D.M., K.E.) and Cardiac Surgery (H.P.), University of Michigan, Ann Arbor; Cardiology Division, University of Salerno, Salerno, Italy (E.B.); Department of Cardiology, Robert Bosch Hospital, Stuttgart, Germany (U.S.); Departments of Medicine and Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.P.); Division of Cardiothoracic Surgery, Cedars-Sinai Med Center, Los Angeles, CA (A.K.); Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany (H.-H.E.); Hopital Bichat, Université Paris, Paris, France (G.J.); Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia (F.R.); and Royal Brompton & Harefield NHS Trust, Cardiology and Aortic Centre, London, UK (C.A.N.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019359DOI Listing
October 2016

Antithrombotic Therapy in Patients With Peripheral Artery Disease.

Authors:
Marc P Bonaca

JAMA Cardiol 2016 10;1(7):803-804

TIMI Study Group, Brigham and Women's Hospital Heart & Vascular Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamacardio.2016.2797DOI Listing
October 2016

Peripheral Revascularization in Patients With Peripheral Artery Disease With Vorapaxar: Insights From the TRA 2°P-TIMI 50 Trial.

JACC Cardiovasc Interv 2016 10;9(20):2157-2164

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcin.2016.07.034DOI Listing
October 2016

Antiplatelet Therapy for Long-term Secondary Prevention After Myocardial Infarction.

JAMA Cardiol 2016 09;1(6):627-8

Thrombolysis in Myocardial Infarction Study Group, Brigham and Women's Hospital Heart and Vascular Center, Boston, Massachusetts2Deputy Editor, JAMA Cardiology.

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http://dx.doi.org/10.1001/jamacardio.2016.2110DOI Listing
September 2016

Prevention of Stroke with Ticagrelor in Patients with Prior Myocardial Infarction: Insights from PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54).

Circulation 2016 Sep 30;134(12):861-71. Epub 2016 Aug 30.

From TIMI Study Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (M.P.B., D.L.B., E.G., D.A.M., E.B., M.S.); Tokai University School of Medicine; Institute of Medical Science, Isehara, Japan (S.G.); FACT, DHU-FIRE INSERM Unité 1148, Assistance Publique-Hôpitaux de Paris and Université Paris Diderot, Paris, France, and NHLI Imperial College, Royal Brompton Hospital, London, UK (P.G.S.); University of Sheffield, United Kingdom (R.F.S.); Division of Cardiology, Newark Beth Israel Medical Center, Rutgers-New Jersey Medical School, Newark (M.C.); Brigham and Women's Hospital and Harvard Clinical Research Institute, Harvard Medical School, Boston, MA (L.M.); CWZ Hospital, Nijmegen, The Netherlands (T.O.O.); Cardiology Research and Production complex MH RF, Moscow, Russia (M.R.); Internal Cardiology Department, University Hospital and Medical faculty, Brno, Czech Republic (J.S.); Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea (K.-B.S.); Heart Institute, Intervention Center, People Hospital of Peking University, China (D.H.); Life Fourways Hospital, Randburg, South Africa (A.J.D.); and AstraZeneca, Mölndal, Sweden (E.J., P.H.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024637DOI Listing
September 2016

Universal Classification System Type of Incident Myocardial Infarction in Patients With Stable Atherosclerosis: Observations From Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)-TIMI 50.

J Am Heart Assoc 2016 07 18;5(7). Epub 2016 Jul 18.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1161/JAHA.116.003237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015369PMC
July 2016

Atherothrombotic Risk Stratification and the Efficacy and Safety of Vorapaxar in Patients With Stable Ischemic Heart Disease and Previous Myocardial Infarction.

Circulation 2016 Jul;134(4):304-13

From the TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., M.P.B., E.B., P.H., S.A.M., M.S.S., B.M.S., D.A.M.); South Australian Health and Research Institute, Flinders University and Medical Centre, Adelaide (P.E.A.); Division of Cardiovascular Diseases, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago (R.C.); Department of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy (G.M.D.F.); Lady Davis Carmel Medical Center and the Ruth and Bruce Rappaport School of Medicine, Technion, Haifa, Israel (B.S.L.); and IV Divisione Cardiologia, Azienda Ospedaliera Niguarda Ca' Granda, Milan, Italy (P.A.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019861DOI Listing
July 2016

Reduction in Ischemic Events With Ticagrelor in Diabetic Patients With Prior Myocardial Infarction in PEGASUS-TIMI 54.

J Am Coll Cardiol 2016 Jun 1;67(23):2732-2740. Epub 2016 Apr 1.

Département Hospitalo-Universitaire-Fibrosis, Inflammation, REmodelling, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Université Paris-Diderot, Sorbonne-Paris Cité, and the French Alliance for Cardiovascular Clinical Trials, an F-CRIN network, INSERM U-1148, Paris, France.

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http://dx.doi.org/10.1016/j.jacc.2016.03.529DOI Listing
June 2016

Outcomes in Stable Patients With Previous Atherothrombotic Events Receiving Vorapaxar Who Experience a New Acute Coronary Event (from TRA2°P-TIMI 50).

Am J Cardiol 2016 Apr 14;117(7):1055-8. Epub 2016 Jan 14.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029149163000
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http://dx.doi.org/10.1016/j.amjcard.2015.12.052DOI Listing
April 2016

Acute Limb Ischemia and Outcomes With Vorapaxar in Patients With Peripheral Artery Disease: Results From the Trial to Assess the Effects of Vorapaxar in Preventing Heart Attack and Stroke in Patients With Atherosclerosis-Thrombolysis in Myocardial Infarction 50 (TRA2°P-TIMI 50).

Circulation 2016 Mar 29;133(10):997-1005. Epub 2016 Jan 29.

From TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA(M.P.B., J.A.G., B.M.S., S.A.H., E.B., D.A.M.); Dartmouth-Hitchcock Heart and Vascular Center, Geisel School of Medicine at Dartmouth, Lebanon, NH(M.A.C.); and Wiener Cardiovascular Institute and Marie-Jose and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, NY (J.O.).

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http://circ.ahajournals.org/content/early/2016/01/29/CIRCULA
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http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019355DOI Listing
March 2016

Efficacy and Safety of Vorapaxar With and Without a Thienopyridine for Secondary Prevention in Patients With Previous Myocardial Infarction and No History of Stroke or Transient Ischemic Attack: Results from TRA 2°P-TIMI 50.

Circulation 2015 Nov 3;132(20):1871-9. Epub 2015 Sep 3.

From TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., M.P.B., S.A.M., B.M.S., E.B., D.A.M.); Department of Cardiovascular Medicine, Flinders Cardiovascular Center, Adelaide, Australia (P.E.A.); Cardiovascular Division, Pontificia Universidad Catolica de Chile, Santiago, Chile (R.L.C.); Department of Cardiology, Military Hospital, Budapest, Hungary (R.G.K.); and Green Lane Cardiovascular Research Unit, Auckland City Hospital, Auckland, New Zealand (H.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.015042DOI Listing
November 2015

Prognostic performance of a high-sensitivity assay for cardiac troponin I after non-ST elevation acute coronary syndrome: Analysis from MERLIN-TIMI 36.

Eur Heart J Acute Cardiovasc Care 2015 Oct 23;4(5):431-40. Epub 2014 Dec 23.

Department of Medicine, Brigham and Women's Hospital, Boston, USA.

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http://dx.doi.org/10.1177/2048872614564081DOI Listing
October 2015

Editorial on PEGASUS-TIMI 54.

Eur Heart J Cardiovasc Pharmacother 2015 Oct 23;1(4):217-9. Epub 2015 Jun 23.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA

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http://dx.doi.org/10.1093/ehjcvp/pvv030DOI Listing
October 2015

Long-term use of ticagrelor in patients with prior myocardial infarction.

N Engl J Med 2015 May 14;372(19):1791-800. Epub 2015 Mar 14.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (M.P.B., D.L.B., G.M., M.P.F., K.I., S.A.M., S.D.W., E.B., M.S.S.); the Cardiovascular Division, Department of Medicine, Newark Beth Israel Medical Center, Rutgers-New Jersey Medical School, Newark (M.C.); French Alliance for Cardiovascular Trials, Département Hospitalo-Universitaire Fibrosis, Inflammation, Remodeling, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, INSERM Unité 1148, and Université Paris-Diderot, Sorbonne Paris Cité - all in Paris (P.G.S.); National Heart and Lung Institute, Royal Brompton Hospital, Imperial College, London (P.G.S.), and Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom (R.F.S.); AstraZeneca, Mölndal, Sweden (E.C.J., O.B., P.H.); Icahn School of Medicine at Mount Sinai, New York (S.B.); Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (T.O.O.); Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland (A.B.); Montreal Heart Institute, Université de Montréal, Montreal (P.T.); Cardiology Research Center, Moscow (M.R.); Kerckhoff Heart Center, Bad Nauheim, and University of Giessen, Giessen - both in Germany (C.H.); Department of Medicine (Cardiology), Tokai University School of Medicine, Isehara, Japan (S.G.); University Hospital, Jihlavska, Brno, Czech Republic (J.S.); Heart Institute (InCor)-University of São Paulo Medical School, São Paulo (J.C.N.); and the Department of Cardiology, Military Hospital, Budapest, Hungary (R.G.K.).

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http://dx.doi.org/10.1056/NEJMoa1500857DOI Listing
May 2015

Diagnosis and management of acute aortic syndromes: dissection, intramural hematoma, and penetrating aortic ulcer.

Curr Cardiol Rep 2014 ;16(10):536

Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s11886-014-0536-xDOI Listing
April 2015

Pharmacological treatment and current management of peripheral artery disease.

Circ Res 2015 Apr;116(9):1579-98

From the Vascular Medicine Section, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCRESAHA.114.303505DOI Listing
April 2015

Vorapaxar in patients with diabetes mellitus and previous myocardial infarction: findings from the thrombin receptor antagonist in secondary prevention of atherothrombotic ischemic events-TIMI 50 trial.

Circulation 2015 Mar 13;131(12):1047-53. Epub 2015 Feb 13.

From TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (M.A.C., B.M.S., M.P.B., S.A.M., E.B., D.A.M.); University of Florida College of Medicine, Jacksonville (D.J.A.); Milpark Hospital, Johannesburg, South Africa (A.J.D.); Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital/Östra, Gothenburg, Sweden (M.D.); Santo Andre's Hospital, Leiria, Portugal (J.M.); Department of Cardiology, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands (T.O.O.); and Third Division of Cardiology, Medical University of Silesia, Katowice, Poland (M.T.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365950PMC
March 2015

Efficacy and safety of vorapaxar as approved for clinical use in the United States.

J Am Heart Assoc 2015 Mar 19;4(3):e001505. Epub 2015 Mar 19.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (G.M., M.P.B., E.B., S.A.M., B.M.S., D.A.M.).

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http://dx.doi.org/10.1161/JAHA.114.001505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392433PMC
March 2015

Coronary stent thrombosis with vorapaxar versus placebo: results from the TRA 2° P-TIMI 50 trial.

J Am Coll Cardiol 2014 Dec 1;64(22):2309-17. Epub 2014 Dec 1.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2014.09.037DOI Listing
December 2014

New ischemic stroke and outcomes with vorapaxar versus placebo: results from the TRA 2 °P-TIMI 50 trial.

J Am Coll Cardiol 2014 Dec 1;64(22):2318-26. Epub 2014 Dec 1.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2014.07.997DOI Listing
December 2014

Diagnostic performance of copeptin in patients with acute nontraumatic chest pain: BWH-TIMI ED chest pain study.

Clin Cardiol 2014 Apr 22;37(4):227-32. Epub 2014 Jan 22.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/clc.22244DOI Listing
April 2014

Prognostic performance of multiple biomarkers in patients with non-ST-segment elevation acute coronary syndrome: analysis from the MERLIN-TIMI 36 trial (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndromes-Thrombolysis In Myocardial Infarction 36).

J Am Coll Cardiol 2014 Apr 13;63(16):1644-53. Epub 2014 Feb 13.

TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2013.12.034DOI Listing
April 2014

Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial.

Am Heart J 2014 Apr 6;167(4):437-444.e5. Epub 2014 Jan 6.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2013.12.020DOI Listing
April 2014

Primary Stroke Prevention: Medical Therapy Versus Revascularization.

Interv Cardiol Clin 2014 Jan 29;3(1):1-11. Epub 2013 Sep 29.

Vascular Medicine Section, Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.iccl.2013.08.003DOI Listing
January 2014

Evaluation of the diagnostic performance of heart-type fatty acid binding protein in the BWH-TIMI ED chest pain study.

J Thromb Thrombolysis 2013 Nov;36(4):361-7

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, 1st Floor Offices, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s11239-013-0870-7DOI Listing
November 2013

Ticagrelor for acute coronary syndromes.

Expert Rev Cardiovasc Ther 2013 Nov 23;11(11):1473-84. Epub 2013 Oct 23.

TIMI Study Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1586/14779072.2013.839205DOI Listing
November 2013

Real-world application of "delta" troponin: diagnostic and prognostic implications.

J Am Coll Cardiol 2013 Oct 7;62(14):1239-1241. Epub 2013 Aug 7.

Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2013.06.049DOI Listing
October 2013

Management of asymptomatic carotid artery stenosis.

Curr Treat Options Cardiovasc Med 2013 Apr;15(2):252-63

Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s11936-013-0237-6DOI Listing
April 2013

Elevated concentration of placental growth factor (PlGF) and long term risk in patients with acute coronary syndrome in the PROVE IT-TIMI 22 trial.

J Thromb Thrombolysis 2012 Aug;34(2):222-8

Thrombolysis in Myocardial Infarction (TIMI) Study Group, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 350 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s11239-012-0704-zDOI Listing
August 2012

Diagnostic evaluation of the MRP-8/14 for the emergency assessment of chest pain.

J Thromb Thrombolysis 2012 Aug;34(2):229-34

TIMI Study Group, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s11239-012-0705-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113032PMC
August 2012

Vorapaxar in the secondary prevention of atherothrombotic events.

N Engl J Med 2012 Apr 24;366(15):1404-13. Epub 2012 Mar 24.

Thrombolysis in Myocardial Infarction (TIMI) Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa1200933
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http://dx.doi.org/10.1056/NEJMoa1200933DOI Listing
April 2012

Role of ST2 in non-ST-elevation acute coronary syndrome in the MERLIN-TIMI 36 trial.

Clin Chem 2012 Jan 17;58(1):257-66. Epub 2011 Nov 17.

TIMI Study Group, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1373/clinchem.2011.173369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277435PMC
January 2012

Central obesity and cardiovascular outcomes in patients with acute coronary syndrome: observations from the MERLIN-TIMI 36 trial.

Heart 2011 Nov 23;97(21):1782-7. Epub 2011 Aug 23.

Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19103, USA.

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http://dx.doi.org/10.1136/heartjnl-2011-300231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769867PMC
November 2011

SCH 530348: a novel oral thrombin receptor antagonist.

Future Cardiol 2009 Sep;5(5):435-42

TIMI Study Group, Brigham & Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.2217/fca.09.27DOI Listing
September 2009

Antithrombotics in acute coronary syndromes.

J Am Coll Cardiol 2009 Sep;54(11):969-84

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.jacc.2009.03.083DOI Listing
September 2009