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Severity: Notice

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Filename: controllers/Author.php

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Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 31106365

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30962103

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30800043

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30685352

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30451567

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30419504

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 29887288

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 29355479

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 29318700

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 29282813

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 28984064

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 28222523

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 28167839

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 27867340

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 27844057

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 27799900

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 27534266

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 27302362

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 27030752

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26696850

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26635555

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26546125

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26468184

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26302801

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26269195

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26089807

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25818748

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25803843

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25781069

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25740605

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25461715

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25384568

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25027326

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25009316

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24879992

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24801365

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24752061

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24366545

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24291518

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24050403

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24048855

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24039182

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24030951

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23973755

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23969234

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23825664

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23604404

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23570900

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23542787

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23342120

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23220201

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23216354

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23165261

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23054839

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22563308

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22541297

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22541285

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22539351

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22459873

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22310387

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22101982

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22024278

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21814183

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21552537

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21364922

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21262400

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21068296

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20600907

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20596738

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20522013

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20494326

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20204153

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20025970

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19783846

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19740365

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19698958

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19660545

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19584316

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 18940310

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 18812457

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 18648535

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 18593877

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 18203754

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 17998315

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 17785520

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 17329422

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 16963267

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 16520905

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 16242644

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 15353219

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 12931788

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1306
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 336
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 12576186

Filename: controllers/Author.php

Line Number: 1528

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1528
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
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Publications Authored by Mara Dierssen | PubFacts
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Publications by authors named "Mara Dierssen"

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Pergola-web: a web server for the visualization and analysis of longitudinal behavioral data using repurposed genomics tools and standards.

Nucleic Acids Res 2019 Jul;47(W1):W600-W604

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1093/nar/gkz414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602478PMC
July 2019

Effect of epigallocatechin gallate on the body composition and lipid profile of down syndrome individuals: Implications for clinical management.

Clin Nutr 2019 Jun 8. Epub 2019 Jun 8.

Integrative Pharmacology and Systems Neuroscience Research Group, Neurosciences Research Program, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain; CIBER Fisiopatología Obesidad y Nutrición, Instituto Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.05.028DOI Listing
June 2019

Metabolomics predicts the pharmacological profile of new psychoactive substances.

J Psychopharmacol 2019 Mar 19;33(3):347-354. Epub 2018 Nov 19.

1 Integrative Pharmacology and Systems Neuroscience Research Group, Neurosciences Research Program, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.

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http://journals.sagepub.com/doi/10.1177/0269881118812103
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http://dx.doi.org/10.1177/0269881118812103DOI Listing
March 2019

A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome.

Clin Nutr 2019 Mar 25. Epub 2019 Mar 25.

IMIM-Hospital del Mar Medical Research Institute, E-08003 Barcelona, Spain; University Pompeu Fabra (CEXS-UPF), E-08003 Barcelona, Spain; Center for Genomic Regulation (CRG), E-08003 Barcelona, Spain; CIBER of Rare Diseases (CIBERER), E-08003 Barcelona, Spain; The Barcelona Institute of Science and Technology, E-08003 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.02.028DOI Listing
March 2019

Pergola: Boosting Visualization and Analysis of Longitudinal Data by Unlocking Genomic Analysis Tools.

iScience 2018 Nov 26;9:244-257. Epub 2018 Oct 26.

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231116PMC
November 2018

Translating molecular advances in Down syndrome and Fragile X syndrome into therapies.

Eur Neuropsychopharmacol 2018 06 7;28(6):675-690. Epub 2018 Jun 7.

Institut du Cerveau et de la Moelle épinière, CNRS UMR7225, INSERM U1127, UPMC, Hôpital de la Pitié-Salpêtrière, 47 Bd de l'Hôpital, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2018.03.006DOI Listing
June 2018

Extinction and reinstatement of an operant responding maintained by food in different models of obesity.

Addict Biol 2018 03 28;23(2):544-555. Epub 2017 Dec 28.

Laboratori de Neurofarmacologia. Departament de Ciencies Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1111/adb.12597DOI Listing
March 2018

Time-course and dynamics of obesity-related behavioral changes induced by energy-dense foods in mice.

Addict Biol 2018 03 10;23(2):531-543. Epub 2018 Jan 10.

Cellular and Systems Neurobiology, Systems Biology Program, The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Spain.

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http://dx.doi.org/10.1111/adb.12595DOI Listing
March 2018

Anomalous White Matter Structure and the Effect of Age in Down Syndrome Patients.

J Alzheimers Dis 2017 ;57(1):61-70

Integrative Pharmacology and Neuroscience Systems Research Group, Hospital del Mar Medical Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-161112DOI Listing
February 2018

Combined Treatment With Environmental Enrichment and (-)-Epigallocatechin-3-Gallate Ameliorates Learning Deficits and Hippocampal Alterations in a Mouse Model of Down Syndrome.

eNeuro 2016 Sep-Oct;3(5). Epub 2016 Nov 8.

Cellular and Systems Neurobiology, Systems Biology Program, the Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), 08003, Barcelona, Spain; Human Pharmacology and Clinical Neurosciences Research Group, Neurosciences Research Program, Hospital Del Mar Medical Research Institute (IMIM), Barcelona, 08003, Spain; Centro De Investigación Biomédica En Red De Enfermedades Raras, Madrid, 28029, Spain.

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http://dx.doi.org/10.1523/ENEURO.0103-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099603PMC
October 2017

Potential Role of (-)-Epigallocatechin-3-Gallate (EGCG) in the Secondary Prevention of Alzheimer Disease.

Curr Drug Targets 2017 ;18(2):174-195

Human Pharmacology and Clinical Neurosciences Research Group, Neurosciences Research Program, IMIM (Hospital del Mar Medical Research Institute), Doctor Aiguader, 88, 08003, Barcelona, Spain.

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http://dx.doi.org/10.2174/1389450116666150825113655DOI Listing
September 2017

Infralimbic Neurotrophin-3 Infusion Rescues Fear Extinction Impairment in a Mouse Model of Pathological Fear.

Neuropsychopharmacology 2017 01 18;42(2):462-472. Epub 2016 Aug 18.

Systems Biology Programme, Centre for Genomic Regulation (CRG)/Barcelona Biomedical Research Park, Barcelona, Spain.

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http://dx.doi.org/10.1038/npp.2016.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399232PMC
January 2017

VNTR-DAT1 and COMTVal158Met Genotypes Modulate Mental Flexibility and Adaptive Behavior Skills in Down Syndrome.

Front Behav Neurosci 2016 17;10:193. Epub 2016 Oct 17.

Integrative Pharmacology and Systems Neuroscience Group, Neurosciences Research Program, IMIM-Hospital del Mar Medical Research InstituteBarcelona, Spain; Department of Experimental and Health Sciences, Universidad Pompeu FabraBarcelona, Spain; CIBER Fisiopatología Obesidad y Nutrición, Instituto Salud Carlos IIIMadrid, Spain.

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http://dx.doi.org/10.3389/fnbeh.2016.00193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065956PMC
October 2016

Overexpression of Dyrk1A, a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex.

J Neurosci 2016 Mar;36(13):3648-59

Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, 08003 Barcelona, Spain, Pompeu Fabra University (UPF), 08003 Barcelona, Spain, Centre for Biomedical Research on Rare Diseases (CIBERER) 08003 Barcelona, Spain,

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http://dx.doi.org/10.1523/JNEUROSCI.2517-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601739PMC
March 2016

Reduced cortical neurotransmitter receptor complex levels in fetal Down syndrome brain.

Amino Acids 2016 Jan 13;48(1):103-16. Epub 2015 Aug 13.

Department of Pediatrics, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00726-015-2062-6DOI Listing
January 2016

Semantic Verbal Fluency Pattern, Dementia Rating Scores and Adaptive Behavior Correlate With Plasma Aβ42 Concentrations in Down Syndrome Young Adults.

Front Behav Neurosci 2015 18;9:301. Epub 2015 Nov 18.

Neurosciences Research Program, Integrative Pharmacology and Systems Neuroscience Research Group, IMIM-Institut de Hospital del Mar d'Investigacions Mèdiques Barcelona, Spain ; Department of Experimental and Health Sciences, Universitat Pompeu Fabra Barcelona, Spain ; CIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III Madrid, Spain.

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http://dx.doi.org/10.3389/fnbeh.2015.00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649024PMC
December 2015

Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome.

Front Behav Neurosci 2015 11;9:330. Epub 2015 Dec 11.

Systems Biology Program, Cellular and Systems Neurobiology, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology Barcelona, Spain ; Centre for Genomic Regulation, Universitat Pompeu Fabra Barcelona, Spain ; Centro de Investigación Biomédica en Red de Enfermedades Raras Barcelona, Spain.

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http://dx.doi.org/10.3389/fnbeh.2015.00330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675859PMC
December 2015

Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges.

BMC Genomics 2015 Nov 6;16:907. Epub 2015 Nov 6.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Rosselló 149-153, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12864-015-2160-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636806PMC
November 2015

New Perspectives for the Rescue of Cognitive Disability in Down Syndrome.

J Neurosci 2015 Oct;35(41):13843-52

Mother Infant Research Institute, Floating Hospital for Children and Department of Pediatrics, Tufts University School of Medicine, Boston, Massachusetts 02111

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http://www.jneurosci.org/content/35/41/13843.full.pdf
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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2775-15.2
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http://dx.doi.org/10.1523/JNEUROSCI.2775-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608177PMC
October 2015

From neural to genetic substrates of panic disorder: Insights from human and mouse studies.

Eur J Pharmacol 2015 Jul 24;759:127-41. Epub 2015 Mar 24.

Cellular & Systems Neurobiology, Systems Biology Program, Center for Genomic Regulation (CRG), E-08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), E-08003 Barcelona, Spain; CIBER de Enfermedades Raras (CIBERER), E-08003 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.03.039DOI Listing
July 2015

A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain.

Amino Acids 2015 Jun 5;47(6):1127-34. Epub 2015 Mar 5.

Department of Pediatrics, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00726-015-1941-1DOI Listing
June 2015

Anomalous brain functional connectivity contributing to poor adaptive behavior in Down syndrome.

Cortex 2015 Mar 28;64:148-56. Epub 2014 Oct 28.

Human Pharmacology and Clinical Neurosciences, Hospital del Mar Medical Research Institute, Barcelona, Spain; CIBER-Fisiopatología de la Obesidad y Nutrición (CIBEROBN), S. de Compostela, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2014.10.012DOI Listing
March 2015

Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases.

Molecules 2015 Mar 13;20(3):4655-80. Epub 2015 Mar 13.

Human Pharmacology and Clinical Neurosciences Research Group, Neurosciences Research Program, IMIM-Institut Hospital del Mar d'Investigacions Mèdiques, Dr. Aiguader 88, Barcelona 08003, Spain.

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http://www.infoalimentario.com/web/wp-content/uploads/2013/0
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http://repositori.upf.edu/bitstream/handle/10230/23764/rodri
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http://www.mdpi.com/1420-3049/20/3/4655/
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http://dx.doi.org/10.3390/molecules20034655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272603PMC
March 2015

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

PLoS Genet 2015 Mar 24;11(3):e1005062. Epub 2015 Mar 24.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France; Institut Clinique de la Souris, PHENOMIN, GIE CERBM, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pgen.1005062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372517PMC
March 2015

Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder.

Hum Mol Genet 2014 Dec 15;23(24):6481-94. Epub 2014 Jul 15.

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII, Spain, Neurosciences Program, Institut Hospital del Mar D'Investigacions Mèdiques (IMIM), Barcelona 08003, Spain,

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http://dx.doi.org/10.1093/hmg/ddu368DOI Listing
December 2014

Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice.

Acta Neuropathol Commun 2014 Nov 11;2:147. Epub 2014 Nov 11.

Cellular and Systems Neurobiology, Systems Biology Program, Centre for Genomic Regulation (CRG), Barcelona Biomedical Research Park (PRBB) building, Room 522.04; C/ Dr. Aiguader 88, E-08003, Barcelona, Spain.

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http://dx.doi.org/10.1186/s40478-014-0147-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236452PMC
November 2014

The role of nicotinic receptors in shaping and functioning of the glutamatergic system: a window into cognitive pathology.

Neurosci Biobehav Rev 2014 Oct 29;46 Pt 2:315-25. Epub 2014 May 29.

Systems Biology Program, Centre for Genomic Regulation (CRG), Barcelona E-08003, Spain; University Pompeu Fabra (UPF), Spain; CIBER de Enfermedades Raras (CIBERER), Barcelona E-08003, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2014.05.012DOI Listing
October 2014

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

Neurobiol Dis 2014 Sep 4;69:65-75. Epub 2014 May 4.

Univ Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, UMR CNRS 8251, 75205 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.04.016DOI Listing
September 2014

Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndrome.

Genetics 2014 Jul 21;197(3):899-912. Epub 2014 Apr 21.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, 67404 Illkirch, France Centre National de la Recherche Scientifique, UMR7104, Illkirch, France Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France Université de Strasbourg, 67400 Illkirch, France Institut Clinique de la Souris, PHENOMIN, Groupement d'Intérêt Economique Centre Européen de Recherche en Biologie Moléculaire, 67404 Illkirch, France

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http://dx.doi.org/10.1534/genetics.114.165241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096369PMC
July 2014

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.

Mol Nutr Food Res 2014 Feb 14;58(2):278-88. Epub 2013 Sep 14.

Human Pharmacology and Clinical Neurosciences Research Group-Neurosciences Program, IMIM-Hospital del Mar Research Institute, Barcelona, Spain; Cardiovascular Risk and Nutrition Research Group-Inflammatory and Cardiovascular Disorders Program, IMIM-Hospital del Mar Research Institute, and CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Barcelona, Spain; University Pompeu Fabra, CEXS-UPF, Barcelona, Spain.

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http://dx.doi.org/10.1002/mnfr.201300325DOI Listing
February 2014

Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A.

Neurobiol Dis 2013 Dec 20;60:18-31. Epub 2013 Aug 20.

Systems Biology Program, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, E-08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Dr. Aiguader 88, E-08003 Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Dr. Aiguader 88, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.nbd.2013.08.008DOI Listing
December 2013

Carnitine palmitoyltransferase 1C deficiency causes motor impairment and hypoactivity.

Behav Brain Res 2013 Nov 21;256:291-7. Epub 2013 Aug 21.

Department of Basic Sciences, Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya (UIC), 08195 Sant Cugat del Vallés, Spain; Centro de Investigación Biomédica en Red (CIBER)-Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.

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http://dx.doi.org/10.1016/j.bbr.2013.08.004DOI Listing
November 2013

A commentary on: Overexpression of Dyrk1A inhibits choline acetyltransferase induction by oleic acid in cellular models of Down syndrome.

Authors:
Mara Dierssen

Exp Neurol 2013 Sep 6;247:110-2. Epub 2013 Apr 6.

Systems Biology Programme, Centre for Genomic Regulation, Dr. Aiguader 88, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.expneurol.2013.03.024DOI Listing
September 2013

Hippocampal hyperexcitability underlies enhanced fear memories in TgNTRK3, a panic disorder mouse model.

J Neurosci 2013 Sep;33(38):15259-71

Systems Biology Programme, Centre for Genomic Regulation, E-08003 Barcelona, Spain, Universitat Pompeu Fabra, E-08003 Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Raras, E-08003 Barcelona, Spain, Department of Stem Cells and Regeneration, Sanford-Burnham Medical Research Institute, La Jolla, California 92037, and Institute of Biology, Otto-von-Guericke University Magdeburg, and Center for Behavioral Brain Sciences, D39120 Magdeburg, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.2161-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618414PMC
September 2013

Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes.

Neuron 2013 Sep;79(6):1152-68

Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas and Universidad Miguel Hernández, Sant Joan d'Alacant 03550, Spain.

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http://dx.doi.org/10.1016/j.neuron.2013.07.010DOI Listing
September 2013

Dyrk1A is dynamically expressed on subsets of motor neurons and in the neuromuscular junction: possible role in Down syndrome.

PLoS One 2013 16;8(1):e54285. Epub 2013 Jan 16.

Genes and Disease Program, Center for Genomic Regulation-CRG, Pompeu Fabra University, Barcelona Biomedical Research Park-PRBB and CIBER de Enfermedades Raras-CIBERER, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054285PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546979PMC
August 2013

Functional implications of hippocampal adult neurogenesis in intellectual disabilities.

Amino Acids 2013 Jul 20;45(1):113-31. Epub 2013 Apr 20.

Systems Biology Program, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1007/s00726-013-1489-xDOI Listing
July 2013

Targeting the endocannabinoid system in the treatment of fragile X syndrome.

Nat Med 2013 May 31;19(5):603-7. Epub 2013 Mar 31.

Departament de Ciències Experimentals i de la Salut (DCEXS), Universitat Pompeu Fabra (UPF), Barcelona, Spain.

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http://dx.doi.org/10.1038/nm.3127DOI Listing
May 2013

AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway.

J Neurochem 2013 Feb;124(3):347-62

Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa UAM-CSIC, and CIBER de Enfermedades Raras (CIBERER), Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1111/jnc.12096DOI Listing
February 2013

Down syndrome: the brain in trisomic mode.

Authors:
Mara Dierssen

Nat Rev Neurosci 2012 12;13(12):844-58

Genes and Disease Programme, Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Centro de Investigación Biomédica en Red de Enfermedades Raras, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1038/nrn3314DOI Listing
December 2012

Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice.

Proc Natl Acad Sci U S A 2012 Nov 10;109(45):E3136-45. Epub 2012 Oct 10.

EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1073/pnas.1206506109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494930PMC
November 2012

Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice.

Front Mol Neurosci 2012 3;5:58. Epub 2012 May 3.

Genomic Regulation Center, Parc de Recerca Biomèdica de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras Barcelona, Spain.

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http://dx.doi.org/10.3389/fnmol.2012.00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342529PMC
October 2012

Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present, and future.

Prog Brain Res 2012 ;197:1-14

Neurosciences Research Programme, IMIM-Hospital del Mar Research Institute and CIBEROBN, Barcelona, Spain.

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http://dx.doi.org/10.1016/B978-0-444-54299-1.00001-7DOI Listing
September 2012

Preface.

Prog Brain Res 2012 ;197:vii

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http://dx.doi.org/10.1016/B978-0-444-54299-1.00019-4DOI Listing
September 2012

Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.

J Biol Chem 2012 Jun 26;287(25):21224-32. Epub 2012 Apr 26.

From the Department of Basic Sciences, Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya, E-08195 Sant Cugat del Vallès, Spain.

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http://dx.doi.org/10.1074/jbc.M111.337493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375544PMC
June 2012

Overexpression of α3/α5/β4 nicotinic receptor subunits modifies impulsive-like behavior.

Drug Alcohol Depend 2012 May 22;122(3):247-52. Epub 2011 Oct 22.

Laboratory of Neuropharmacology, Pompeu Fabra University, PRBB, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.drugalcdep.2011.09.027DOI Listing
May 2012

Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.

Neuropsychopharmacology 2011 Nov 3;36(12):2395-405. Epub 2011 Aug 3.

Developmental Neurobiology and Regeneration Unit, Institute for Research in Biomedicine, Parc Cientific de Barcelona, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/npp.2011.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194085PMC
November 2011

Increased opioid dependence in a mouse model of panic disorder.

Front Behav Neurosci 2010 22;3:60. Epub 2010 Feb 22.

Genes and Disease Program, Genomic Regulation Center-CRG, Barcelona Biomedical Research Park-PRBB and CIBER de Enfermedades Raras Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.3389/neuro.08.060.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831706PMC
July 2011

A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain.

J Proteomics 2011 Apr 22;74(4):547-57. Epub 2011 Jan 22.

Department of Pediatrics, Neuroproteomics Division, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.jprot.2011.01.009DOI Listing
April 2011

RhoE deficiency produces postnatal lethality, profound motor deficits and neurodevelopmental delay in mice.

PLoS One 2011 Apr 28;6(4):e19236. Epub 2011 Apr 28.

Department of Chemistry, Biochemistry and Molecular Biology, School of Health Sciences, Universidad CEU Cardenal Herrera, Moncada, Valencia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019236PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084285PMC
April 2011

Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.

PLoS One 2011 Feb 25;6(2):e17010. Epub 2011 Feb 25.

Centre for Genomic Regulation, Barcelona Biomedical Research Park, and CIBER de Enfermedades Raras, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017010PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045383PMC
February 2011

In vivo effects of APP are not exacerbated by BACE2 co-overexpression: behavioural characterization of a double transgenic mouse model.

Amino Acids 2010 Nov 2;39(5):1571-80. Epub 2010 Jul 2.

Neurobehavioural Phenotyping of Mouse Models of Disease, Genes and Disease Program, Center for Genomic Regulation (CRG), Barcelona Biomedical Research Park (PRBB), Dr. Aiguader, 88, 08003, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/s00726-010-0662-8DOI Listing
November 2010

Down syndrome: from understanding the neurobiology to therapy.

J Neurosci 2010 Nov;30(45):14943-5

Department of Pediatrics, Intellectual and Developmental Disabilities Research Center, University of Colorado Denver, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3728-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842485PMC
November 2010

Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.

Neurobiol Dis 2010 Oct 30;40(1):348-59. Epub 2010 Jun 30.

Department of Biological Chemistry and Interdisciplinary Center for Neuronal Computation (ICNC), The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1016/j.nbd.2010.06.011DOI Listing
October 2010

Insights from mouse models to understand neurodegeneration in Down syndrome.

CNS Neurol Disord Drug Targets 2010 Aug;9(4):429-38

Centre de Regulació Genòmica, UPF, Parc de Recerca Biomèdica de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras, Spain.

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August 2010

Cognitive deficits and associated neurological complications in individuals with Down's syndrome.

Lancet Neurol 2010 Jun;9(6):623-33

Department of Pediatrics, University of California Irvine School of Medicine, Orange, CA 92868, USA.

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http://dx.doi.org/10.1016/S1474-4422(10)70112-5DOI Listing
June 2010

Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease.

Neurobiol Dis 2010 Mar 16;37(3):682-91. Epub 2009 Dec 16.

Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, Sant Joan d'Alacant, E-03550, Spain.

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http://dx.doi.org/10.1016/j.nbd.2009.12.006DOI Listing
March 2010

Susceptibility to stress in transgenic mice overexpressing TrkC, a model of panic disorder.

J Psychiatr Res 2010 Feb 20;44(3):157-67. Epub 2009 Aug 20.

Genes and Disease Program, Centre for Genomic Regulation, Universidad Pompeu Fabra, Barcelona Biomedical Research Park (PRBB), Dr. Aiguader 88, Barcelona E-08003, Spain.

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http://dx.doi.org/10.1016/j.jpsychires.2009.07.008DOI Listing
February 2010

Age-associated motor and visuo-spatial learning phenotype in Dyrk1A heterozygous mutant mice.

Neurobiol Dis 2009 Nov 4;36(2):312-9. Epub 2009 Aug 4.

Genes and Disease Program, Center for Genomic Regulation (CRG), Pompeu Fabra University, Barcelona Biomedical Research Park (PRBB) and CIBER de Enfermedades Raras (CIBERER), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.nbd.2009.07.027DOI Listing
November 2009

An animal model of compulsive food-taking behaviour.

Addict Biol 2009 Sep;14(4):373-83

Medimod Pharmacology Services GmbH, Germany.

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http://dx.doi.org/10.1111/j.1369-1600.2009.00175.xDOI Listing
September 2009

Aneuploidy: from a physiological mechanism of variance to Down syndrome.

Physiol Rev 2009 Jul;89(3):887-920

Genes and Disease Program, Genomic Regulation Center-CRG, Pompeu Fabra University, Barcelona Biomedical Research Park, Dr Aiguader 88, PRBB building E, Barcelona 08003, Catalonia, Spain.

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http://dx.doi.org/10.1152/physrev.00032.2007DOI Listing
July 2009

Hypothalamus transcriptome profile suggests an anorexia-cachexia syndrome in the anx/anx mouse model.

Physiol Genomics 2008 Nov 23;35(3):341-50. Epub 2008 Sep 23.

Genes and Disease Program, Center for Genomic Regulation CRG-UPF, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1152/physiolgenomics.90255.2008DOI Listing
November 2008

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

Am J Hum Genet 2008 Oct;83(4):479-88

Programa Gens i Malaltia. Centre de Regulació Genòmica-CRG, UPF, Parc de Recerca Biomèdica de Barcelona-PRBB, Barcelona 08003, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297080050
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http://dx.doi.org/10.1016/j.ajhg.2008.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561933PMC
October 2008

Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development.

Pediatrics 2007 Dec 12;120(6):e1465-71. Epub 2007 Nov 12.

Department of Pharmacology and Toxicology, Institute of Pharmacy and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1542/peds.2006-3448DOI Listing
December 2007

Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice.

J Neurosci 2007 Feb;27(9):2253-60

Genes and Disease Program, Genomic Regulation Center, Universidad Pompeu Fabra, Barcelona Biomedical Research Park, 08003 Barcelona, Spain.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4055-06.2
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http://dx.doi.org/10.1523/JNEUROSCI.4055-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673497PMC
February 2007

Pitfalls and hopes in Down syndrome therapeutic approaches: in the search for evidence-based treatments.

Behav Genet 2006 May 7;36(3):454-68. Epub 2006 Mar 7.

Genes and Disease Program, Genomic Regulation Center, (CRG-UPF), Barcelona Biomedical Research Park, Spain.

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http://dx.doi.org/10.1007/s10519-006-9050-2DOI Listing
May 2006

Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.

Neurobiol Dis 2005 Nov;20(2):392-400

Institut de Neuropatologia, Servei Anatomia Patològica, Hospital Universitari de Bellvitge, carrer Feixa Llarga sn, 08907 Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1016/j.nbd.2005.03.020DOI Listing
November 2005

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome.

Brain Res 2004 Oct;1022(1-2):101-9

Department of Anatomy, Uludag University Medical Faculty, Bursa, Turkey.

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http://dx.doi.org/10.1016/j.brainres.2004.06.075DOI Listing
October 2004

Special interest section--Down's syndrome: postgenomic approaches to neurobiological problems.

Authors:
Mara Dierssen

Genes Brain Behav 2003 Jun;2(3):152-5

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June 2003

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system.

Brain Res 2003 Feb;964(2):250-63

Program in Genes and Disease, Centre de Regulació Genòmica-CRG, Passeig Marítim 37-49, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1016/s0006-8993(02)04069-6DOI Listing
February 2003

Proteomic analysis of the fetal brain.

Proteomics 2002 Nov;2(11):1547-76

Center for Medical Genomics, F. Hoffmann-La Roche, Basel, Switzerland.

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http://dx.doi.org/10.1002/1615-9861(200211)2:11<1547::AID-PROT1547>3.0.CO;2-MDOI Listing
November 2002

Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome.

Behav Brain Res 2002 Aug;134(1-2):185-200

Department of Physiology and Pharmacology, Laboratory of Developmental Neurobiology, University of Cantabria, Avenida Herrera Oria, s/n 39011 Santander, Spain.

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http://dx.doi.org/10.1016/s0166-4328(02)00026-8DOI Listing
August 2002