Mar Hernandez-Guillamon

Mar Hernandez-Guillamon

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Mar Hernandez-Guillamon

Mar Hernandez-Guillamon

Publications by authors named "Mar Hernandez-Guillamon"

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Matrix metalloproteinases and ADAMs in stroke.

Cell Mol Life Sci 2019 Aug 5;76(16):3117-3140. Epub 2019 Jun 5.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Passeig de la Vall d'Hebron, 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00018-019-03175-5DOI Listing
August 2019

Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice.

Alzheimers Res Ther 2019 May 10;11(1):42. Epub 2019 May 10.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1186/s13195-019-0498-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511153PMC
May 2019

Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy.

Front Neurol 2019 13;10:187. Epub 2019 Mar 13.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3389/fneur.2019.00187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424885PMC
March 2019

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome.

Circ Res 2019 Jan;124(1):114-120

From the Department of Neurology, Neurovascular Research Group, Hospital del Mar Medical Research Institute, Universitat Autònoma de Barcelona/DCEXS-Universitat Pompeu Fabra (M.M.-C., C.S.-T., E.G.-S., A.R.-C., A.O., E.C.-G., R.M.V.-H., J.R., J.J.-C.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31353
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http://dx.doi.org/10.1161/CIRCRESAHA.118.313533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501820PMC
January 2019

Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data.

Lancet Neurol 2018 10 14;17(10):885-894. Epub 2018 Aug 14.

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183025
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http://dx.doi.org/10.1016/S1474-4422(18)30253-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143589PMC
October 2018

Simvastatin blocks soluble SSAO/VAP-1 release in experimental models of cerebral ischemia: Possible benefits for stroke-induced inflammation control.

Biochim Biophys Acta Mol Basis Dis 2018 Feb 22;1864(2):542-553. Epub 2017 Nov 22.

Biochemistry and Molecular Biology Department, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.11.014DOI Listing
February 2018

Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease.

Neurobiol Aging 2017 12 5;60:116-128. Epub 2017 Sep 5.

Neurovascular Research Laboratory, Vall d'Hebron Research Insitute, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.08.028DOI Listing
December 2017

Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: A meta-analysis.

Neurology 2017 Aug 26;89(8):820-829. Epub 2017 Jul 26.

From the Stroke Research Centre (A.C., Y.Y., S.M.G., H.R.J., D.J.W.), Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Hemorrhagic Stroke Research Program, Department of Neurology (A.C., A.B., E.E.S., A.V., S.M.G.), Massachusetts General Hospital Stroke Research Center, Harvard Medical School, Boston; Department of Neurosurgery (T.I.), Kushiro City General Hospital, Hokkaido, Japan; Degenerative & Vascular Cognitive Disorders (S.M., B.C., C.C.), Univ Lille, Inserm, CHU Lille, France; Centre for Clinical Brain Sciences (N.S., R.A.-S.S.), University of Edinburgh, UK; Department of Neurology (A.P.), Cliniques Universitaires UCL Saint Luc; Department of Neurology (Y.V., P.L.), CHU Dinant Godinne, Université Catholique de Louvain; Institute of Neuroscience (Y.V., P.L.), Université Catholique de Louvain, Brussels, Belgium; Department of Clinical Neurosciences (J.-C.B.), University of Cambridge, Addenbrooke's Hospital, UK; UMR 894 INSERM-Université Paris 5 (J.-C.B.), Sorbonne Paris Cité, Paris, France; Department of Neurology (M.H.-G., J.M.), Hospital Vall d'Hebron, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Spain; Department of Neurology (D.-W.K., J.S.K.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology (H.N.), Hiroshima Prefectural Hospital, Japan; and Hotchkiss Brain Institute (E.E.S.), University of Calgary, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000004259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580863PMC
August 2017

Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats.

Int J Nanomedicine 2016 29;11:3035-48. Epub 2016 Jun 29.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona; Neurovascular Unit, Department of Neurology, Universitat Autònoma de Barcelona, Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.2147/IJN.S107292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935044PMC
February 2017

Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry.

J Proteomics 2017 01 22;152:243-253. Epub 2016 Nov 22.

Universitat Autònoma de Barcelona, Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.11.014DOI Listing
January 2017

Matrix Metalloproteinases in Alzheimer's Disease and Concurrent Cerebral Microbleeds.

J Alzheimers Dis 2015 ;48(3):711-20

Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.3233/JAD-143186DOI Listing
July 2016

Modulation of Amyloid-β1-40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier.

J Alzheimers Dis 2016 05;53(2):677-91

Neurovascular Research Laboratory, Vall d'Hebron Research Insitute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-150976DOI Listing
May 2016

ApoA1, ApoJ and ApoE Plasma Levels and Genotype Frequencies in Cerebral Amyloid Angiopathy.

Neuromolecular Med 2016 Mar 14;18(1):99-108. Epub 2015 Dec 14.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12017-015-8381-7DOI Listing
March 2016

Identification of Plasma Biomarkers of Human Intracerebral Hemorrhage Subtypes through Microarray Technology.

J Stroke Cerebrovasc Dis 2016 Mar 29;25(3):665-71. Epub 2015 Dec 29.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.11.032DOI Listing
March 2016

Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC).

J Proteomics 2016 Feb 21;133:100-112. Epub 2015 Dec 21.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2015.12.011DOI Listing
February 2016

Plasmatic retinol-binding protein 4 and glial fibrillary acidic protein as biomarkers to differentiate ischemic stroke and intracerebral hemorrhage.

J Neurochem 2016 Jan 17;136(2):416-24. Epub 2015 Dec 17.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/jnc.13419DOI Listing
January 2016

Rat middle cerebral artery occlusion is not a suitable model for the study of stroke-induced spontaneous infections.

PLoS One 2014 12;9(6):e99169. Epub 2014 Jun 12.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain; Neurovascular Unit, Department of Neurology, Universitat Autònoma de Barcelona, Hospital Vall d' Hebron, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099169PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055651PMC
October 2015

Cerebral amyloid angiopathy-related atraumatic convexal subarachnoid hemorrhage: an ARIA before the tsunami.

J Cereb Blood Flow Metab 2015 May 4;35(5):710-7. Epub 2015 Mar 4.

1] Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain [2] Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain.

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http://dx.doi.org/10.1038/jcbfm.2015.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420868PMC
May 2015

NURR1 involvement in recombinant tissue-type plasminogen activator treatment complications after ischemic stroke.

Stroke 2015 Feb 11;46(2):477-84. Epub 2014 Dec 11.

From the Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain (C.M.-Z., M.H.-G., M.P., I.F.-C., D.G., C.C., A.R., J.M.); INSERM UMR-S U919, GIP Cyceron, University of Caen, Caen, France (A.J., A.L.B., I.B., D.V., C.A.); and Neurovascular Unit, Department of Neurology, Vall d'Hebron Hospital, Barcelona, Spain (M.R., J.M.).

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http://dx.doi.org/10.1161/STROKEAHA.114.006826DOI Listing
February 2015

Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model.

J Neurochem 2014 Jul 30;130(2):301-12. Epub 2014 Apr 30.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/jnc.12719DOI Listing
July 2014

Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice.

PLoS One 2013 4;8(9):e73244. Epub 2013 Sep 4.

Neurovascular Research Laboratory, Department of Neurology and Department of Internal Medicine, Universitat Autònoma de Barcelona, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073244PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762828PMC
April 2014

Mild hypothermia protects against oxygen glucose deprivation (OGD)-induced cell death in brain slices from adult mice.

J Neural Transm (Vienna) 2014 Feb 14;121(2):113-7. Epub 2013 Sep 14.

Neurovascular Research Laboratory, Institut de Recerca, Vall d'Hebron Hospital, Universitat Autònoma de Barcelona, Pg Vall d'Hebron 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00702-013-1090-1DOI Listing
February 2014

Fluorescent molecular peroxidation products: a prognostic biomarker of early neurologic deterioration after thrombolysis.

Stroke 2014 Feb 12;45(2):432-7. Epub 2013 Dec 12.

From Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Neurovascular Unit, Department of Neurology, Universitat Autònoma de Barcelona, Barcelona, Spain (V.L., A.B., T.G.-B., A.P., M.H.-G., D.G., A.R., J.M.); Biochemistry and Molecular Biology Research Centre for Nanomedicine, Hospital Universitari Vall d'Hebron, Instituto de Salud Carlos III, Centre for Biomedical Research on Rare Diseases, Barcelona, Spain (C.D., V.R.-S., P.M.-G., A.V.); Neurovascular Unit, Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain (M. Rubiera, M. Ribó, C.A.M., J.A.-S.); Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany (C.E.); and Department of Neurology, University Hospital of Schleswig-Holstein, Kiel, Germany (C.E.).

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http://dx.doi.org/10.1161/STROKEAHA.113.003431DOI Listing
February 2014

Cerebral ischaemia and matrix metalloproteinase-9 modulate the angiogenic function of early and late outgrowth endothelial progenitor cells.

J Cell Mol Med 2013 Dec 15;17(12):1543-53. Epub 2013 Aug 15.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/jcmm.12116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914647PMC
December 2013

Combining statins with tissue plasminogen activator treatment after experimental and human stroke: a safety study on hemorrhagic transformation.

CNS Neurosci Ther 2013 Nov 14;19(11):863-70. Epub 2013 Oct 14.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/cns.12181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493385PMC
November 2013

Genes involved in hemorrhagic transformations that follow recombinant t-PA treatment in stroke patients.

Pharmacogenomics 2013 Apr;14(5):495-504

Neurovascular Research Laboratory & Neurovascular Unit, Department of Neurology, Vall d'Hebron University Hospital, Departamento de Medicina, Universitat Autonoma de Barcelona, Vall d'Hebron Research Institute, 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.2217/pgs.13.19DOI Listing
April 2013

The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients.

Vasc Cell 2013 Feb 6;5(1). Epub 2013 Feb 6.

Neurovascular Research Laboratory and Neurovascular Unit, Neurology and Medicine Department, Universitat Autònoma de Barcelona, Vall d'Hebron Research Institute of Vall d'Hebron Hospital, Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.

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http://dx.doi.org/10.1186/2045-824X-5-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583716PMC
February 2013

Plasma β-amyloid levels in cerebral amyloid angiopathy-associated hemorrhagic stroke.

Neurodegener Dis 2012 17;10(1-4):320-3. Epub 2012 Jan 17.

Neurovascular Research Laboratory, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1159/000333811DOI Listing
August 2012

Differentiating ischemic from hemorrhagic stroke using plasma biomarkers: the S100B/RAGE pathway.

J Proteomics 2012 Aug 11;75(15):4758-65. Epub 2012 Feb 11.

Neurovascular Research Laboratory, Vall d'Hebron University Hospital, Research Institut, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jprot.2012.01.033DOI Listing
August 2012

Evidence for the efficacy of statins in animal stroke models: a meta-analysis.

J Neurochem 2012 Jul 21;122(2):233-43. Epub 2012 May 21.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07773.xDOI Listing
July 2012

VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke.

Cerebrovasc Dis 2012 1;33(1):55-63. Epub 2011 Dec 1.

Neurovascular Research Laboratory, Institut de Recerca, Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1159/000333370DOI Listing
May 2012

A large screening of angiogenesis biomarkers and their association with neurological outcome after ischemic stroke.

Atherosclerosis 2011 May 26;216(1):205-11. Epub 2011 Jan 26.

Neurovascular Research Laboratory and Neurovascular Unit, Neurology and Medicine Department-Universitat Autònoma de Barcelona, Research Institute of the Vall d'Hebron Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.01.030DOI Listing
May 2011

Effects of acute post-treatment with dipyridamole in a rat model of focal cerebral ischemia.

Brain Res 2011 Feb 10;1373:211-20. Epub 2010 Dec 10.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.brainres.2010.12.005DOI Listing
February 2011

Mobilization, endothelial differentiation and functional capacity of endothelial progenitor cells after ischemic stroke.

Microvasc Res 2010 Dec 4;80(3):317-23. Epub 2010 Jun 4.

Neurovascular Research Laboratory, Neurovascular Unit and Neurology Department, Departament de Medicina, Universitat Autònoma de Barcelona,Vall d'Hebron Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.mvr.2010.05.008DOI Listing
December 2010

The proteome of human brain after ischemic stroke.

J Neuropathol Exp Neurol 2010 Nov;69(11):1105-15

Neurovascular Research Laboratory, Neurology Department, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1097/NEN.0b013e3181f8c539DOI Listing
November 2010

Matrix metalloproteinase-13 is activated and is found in the nucleus of neural cells after cerebral ischemia.

J Cereb Blood Flow Metab 2009 Feb 5;29(2):398-410. Epub 2008 Nov 5.

Department of Neurology, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/jcbfm.2008.130DOI Listing
February 2009

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release.

J Leukoc Biol 2008 Jul 7;84(1):207-14. Epub 2008 Apr 7.

Neurovascular Research Laboratory, Neurovascular Unit, Department of Neurology, Universitat Autònoma de Barcelona, Institut de Recerca, Hospital Vall d'Hebron, Pg Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1189/jlb.0907606DOI Listing
July 2008

p53 phosphorylation is involved in vascular cell death induced by the catalytic activity of membrane-bound SSAO/VAP-1.

Biochim Biophys Acta 2008 Jun 29;1783(6):1085-94. Epub 2008 Feb 29.

Departament de Bioquímica i Biologia Molecular, Institut de Neurociències, Facultat de Medicina, Universitat Autònoma de Barcelona, (08193) Bellaterra, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbamcr.2008.02.014DOI Listing
June 2008

Fas system activation in perihematomal areas after spontaneous intracerebral hemorrhage.

Stroke 2008 Jun 10;39(6):1730-4. Epub 2008 Apr 10.

Neurovascular Research Laboratory. Hospital Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1161/STROKEAHA.107.500876DOI Listing
June 2008

MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke.

Stroke 2008 Apr 6;39(4):1121-6. Epub 2008 Mar 6.

Neurovascular Research Laboratory, Neurovascular Unit, Department of Neurology, Universitat Autònoma de Barcelona, Institut de Recerca, Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1161/STROKEAHA.107.500868DOI Listing
April 2008

Sodium bicarbonate enhances membrane-bound and soluble human semicarbazide-sensitive amine oxidase activity in vitro.

J Biochem 2007 Nov 10;142(5):571-6. Epub 2007 Sep 10.

Dept. Bioquímica i Biologia Molecular, Facultat de Medicina, Institut de Neurociències, Universitat Autònoma de Barcelona, Spain.

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https://academic.oup.com/jb/article-lookup/doi/10.1093/jb/mv
Publisher Site
http://dx.doi.org/10.1093/jb/mvm165DOI Listing
November 2007