Publications by authors named "Manuela Cominelli"

24Publications

Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt.

J Clin Invest 2018 04 12;128(4):1688-1706. Epub 2018 Mar 12.

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1172/JCI96342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873854PMC
April 2018

Cavin-2 is a specific marker for detection of well-differentiated liposarcoma.

Biochem Biophys Res Commun 2017 11 1;493(1):660-665. Epub 2017 Sep 1.

Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123, Brescia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.08.135DOI Listing
November 2017

Treatment with anti-FcεRIα antibody exacerbates EAE and T-cell immunity against myelin.

Neurol Neuroimmunol Neuroinflamm 2017 May 14;4(3):e342. Epub 2017 Apr 14.

Department of Clinical Neuroscience (S.M., M. Costanza, R.P.), Foundation Neurological Institute IRCCS C. Besta, Milan; Department of Molecular and Translational Medicine (P.L.P., E.F., M. Cominelli), Pathology Unit, University of Brescia; Department of Experimental Oncology and Molecular Medicine (G.A.), Fondazione IRCCS "Istituto Nazionale dei Tumori," Milan, Italy; and Department of Neurology and Neurological Sciences (L.S.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462602PMC
May 2017

EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide.

J Natl Cancer Inst 2015 May 3;107(5). Epub 2015 Mar 3.

Pathology (MC, BL, MFB, DM, VP, FF, PLP) and Pharmacology Units (CB, MP), Department of Molecular and Translational Medicine, University of Brescia and National Institute of Neuroscience, Italy; Medical Oncology (SG), Neurosurgery (LB), Radiation Oncology (MB), and Neuroradiology Departments (RL), Spedali Civili of Brescia, University of Brescia, Italy; Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells & Gene Therapy, San Raffaele Scientific Institute, Milan (SM, RG); Pathology Unit, Department of Surgical and Morphological Sciences, University of Insubria, Italy (DF); Neurological Institute Besta, Milan, Italy (SP, GF); Herbert Irving Comprehensive Cancer Center, Department of Pathology & Cell Biology and Department of Medicine, Division of Digestive and Liver Diseases, Columbia University, New York, NY (PD); IRCCS San Camillo Hospital, Venice, Italy (MP).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djv041DOI Listing
May 2015

miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression.

Stem Cells 2015 May;33(5):1377-89

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1002/stem.1958DOI Listing
May 2015

Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models.

Dis Model Mech 2013 Sep 5;6(5):1185-97. Epub 2013 Jun 5.

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Via Olgettina 58, Milan 20132, Italy.

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http://dx.doi.org/10.1242/dmm.012096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759338PMC
September 2013

Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.

Cell Stem Cell 2011 Nov;9(5):447-62

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1016/j.stem.2011.09.008DOI Listing
November 2011

Caveolin 1 is a marker of poor differentiation in Rhabdomyosarcoma.

Eur J Cancer 2011 Mar 22;47(5):761-72. Epub 2010 Nov 22.

Department of Biomedical Sciences and Biotechnologies and Interuniversity Institute of Myology, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.

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http://dx.doi.org/10.1016/j.ejca.2010.10.018DOI Listing
March 2011

Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.

Cancer Res 2010 Oct 21;70(19):7500-13. Epub 2010 Sep 21.

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2353DOI Listing
October 2010