Manuel Vazquez-Carrera

Manuel Vazquez-Carrera

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Manuel Vazquez-Carrera

Manuel Vazquez-Carrera

Publications by authors named "Manuel Vazquez-Carrera"

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Correction to: Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.

Mol Neurobiol 2020 Jun;57(6):2887-2888

Departament de Farmacología, Toxicologia i Quimica Terapéutica, Unitat de Farmacologia i Farmacognosia, Facultat de Farmacia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII s/n, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12035-020-01918-1DOI Listing
June 2020

Targeting FGF21 for the Treatment of Nonalcoholic Steatohepatitis.

Trends Pharmacol Sci 2020 Mar 21;41(3):199-208. Epub 2020 Jan 21.

Department of Pharmacology, Toxicology, and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain; Institute of Biomedicine of the University of Barcelona (IBUB), 08028 Barcelona, Spain; Pediatric Research Institute, Hospital Sant Joan de Déu, 08950 Esplugues de Llobregat, Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, 08028 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2019.12.005DOI Listing
March 2020

SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation.

Signal Transduct Target Ther 2020 28;5:14. Epub 2020 Feb 28.

1Department of Pharmacology, Toxicology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona), Research Institute - Pediatric Research Institute, Hospital Sant Joan de Déu, and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41392-020-0114-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046732PMC
February 2020

SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation.

Signal Transduct Target Ther 2020 Feb 28;5(1):14. Epub 2020 Feb 28.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona), Research Institute - Pediatric Research Institute, Hospital Sant Joan de Déu, and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41392-020-0114-1DOI Listing
February 2020

Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes.

Clin Investig Arterioscler 2019 May - Jun;31(3):111-118. Epub 2019 Apr 13.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III, Spain; Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.arteri.2019.01.004DOI Listing
January 2020

Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.

Br J Pharmacol 2019 07 23;176(13):2292-2305. Epub 2019 May 23.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/bph.14678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555855PMC
July 2019

Fatty acid binding protein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage in type 2 diabetes.

Metabolism 2019 07 15;96:12-21. Epub 2019 Apr 15.

Vascular Medicine and Metabolism Unit, Research Unit on Lipids and Atherosclerosis, "Sant Joan" University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Reus, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Institute of Health Carlos III, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00260495193007
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http://dx.doi.org/10.1016/j.metabol.2019.04.007DOI Listing
July 2019

Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75].

Metabolism 2019 Jul 18;96:101-102. Epub 2019 Apr 18.

Pharmacology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Spain; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Barcelona, Spain; Institut de Recerca Sant Joan de Déu (IR-SJD), Esplugues de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.04.009DOI Listing
July 2019

Role of brain c-Jun N-terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high-fat diet pre-clinical model.

J Neurochem 2019 04 27;149(2):255-268. Epub 2019 Mar 27.

Departament de Farmacologia, Toxicologia i Química Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Barcelona, Spain.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jnc.14682
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http://dx.doi.org/10.1111/jnc.14682DOI Listing
April 2019

HSP90 inhibitors as a future therapeutic strategy in diabetes-driven atherosclerosis.

Clin Investig Arterioscler 2017 Mar - Apr;29(2):67-68

Departamento de Farmacología, Toxicología y Química Terapéutica, Facultad de Farmacia y Ciencias de la Alimentación, Universidad de Barcelona, Instituto de Biomedicina de la Universidad de Barcelona (IBUB), Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)-Instituto de Salud Carlos III, Instituto de Investigación-Hospital Sant Joan de Déu.

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https://linkinghub.elsevier.com/retrieve/pii/S02149168173002
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http://dx.doi.org/10.1016/j.arteri.2017.02.001DOI Listing
September 2018

Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.

Mol Neurobiol 2018 Sep 5;55(9):7327-7339. Epub 2018 Feb 5.

Departament de Farmacología, Toxicologia i Quimica Terapéutica, Unitat de Farmacologia i Farmacognosia, Facultat de Farmacia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII s/n, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12035-018-0868-4DOI Listing
September 2018

In search of the "metabolic footprint" in cardiovascular disease.

Clin Investig Arterioscler 2018 Jan - Feb;30(1):28-29

Departamento de Farmacología, Toxicología y Química Terapéutica, Instituto de Biomedicina de la Universidad de Barcelona (IBUB), Facultad de Farmacia y Ciencias de la Alimentación, Universidad de Barcelona, Barcelona, España; Instituto de Investigación Pediátrica, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, España; CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Salud Carlos III, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.arteri.2018.01.001DOI Listing
September 2018

The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling.

Metabolism 2018 08 9;85:59-75. Epub 2018 Mar 9.

Pharmacology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Spain; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Barcelona, Spain; Institut de Recerca Sant Joan de Déu (IR-SJD), Esplugues de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2018.03.005DOI Listing
August 2018

GNIP1 E3 ubiquitin ligase is a novel player in regulating glycogen metabolism in skeletal muscle.

Metabolism 2018 06 18;83:177-187. Epub 2018 Feb 18.

Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Spain; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)-Instituto de Salud Carlos III, Spain.

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http://dx.doi.org/10.1016/j.metabol.2018.02.005DOI Listing
June 2018

Emerging Actors in Diabetic Cardiomyopathy: Heartbreaker Biomarkers or Therapeutic Targets?

Trends Pharmacol Sci 2018 05 28;39(5):452-467. Epub 2018 Mar 28.

Department of Pharmacology, Toxicology, and Therapeutic Chemistry, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain; Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain; Centro de Investigación Biomédica en Red (CIBER) de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2018.02.010DOI Listing
May 2018

Palmitic and Oleic Acid: The Yin and Yang of Fatty Acids in Type 2 Diabetes Mellitus.

Trends Endocrinol Metab 2018 03 28;29(3):178-190. Epub 2017 Dec 28.

Department of Pharmacology, Toxicology, and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Pediatric Research Institute-Hospital Sant Joan de Déu, and Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Avinguda Joan XXIII 27-31, E-08028 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2017.11.009DOI Listing
March 2018

PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders.

Int J Mol Sci 2018 Mar 20;19(3). Epub 2018 Mar 20.

Pharmacology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Institute of Biomedicine of the University of Barcelona (IBUB), Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.3390/ijms19030913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877774PMC
March 2018

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.

Mol Metab 2018 02 19;8:117-131. Epub 2017 Dec 19.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Barcelona, Spain; Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985050PMC
February 2018

VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells.

Diabetologia 2017 11 23;60(11):2262-2273. Epub 2017 Aug 23.

Pharmacology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institut de Biomedicina de la Universidad de Barcelona (IBUB), University of Barcelona, Diagonal 643, E-08028, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00125-017-4401-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078195PMC
November 2017

Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 May 16;1862(5):541-551. Epub 2017 Feb 16.

Department of Molecular Genetics, CARIM School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200 MD Maastricht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2017.02.006DOI Listing
May 2017

The NR4A subfamily of nuclear receptors: potential new therapeutic targets for the treatment of inflammatory diseases.

Expert Opin Ther Targets 2017 Mar 12;21(3):291-304. Epub 2017 Jan 12.

c Department of Pharmacology, Toxicology and Therapeutic Chemistry, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Institut de Recerca Pediàtrica-Hospital Sant Joan de Déu, and Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM)-Instituto de Salud Carlos III, Faculty of Pharmacy, Diagonal 643 , University of Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/14728222.2017.1279146DOI Listing
March 2017

PPARβ/δ and lipid metabolism in the heart.

Biochim Biophys Acta 2016 10 26;1861(10):1569-78. Epub 2016 Jan 26.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Institut de Biomedicina de la UB (IBUB), Faculty of Pharmacy, University of Barcelona, Barcelona, Spain; Institut de Recerca Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2016.01.019DOI Listing
October 2016

Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency.

Diabetes 2016 10 2;65(10):3185-99. Epub 2016 Aug 2.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Institute of Biomedicine of the University of Barcelona, Barcelona, Spain CIBERDEM, Instituto de Salud Carlos III, Madrid, Spain Pediatric Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain

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http://diabetes.diabetesjournals.org/content/diabetes/early/
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https://dr.ntu.edu.sg/bitstream/handle/10220/41419/Heme-Regu
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http://diabetes.diabetesjournals.org/content/diabetes/65/10/
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http://dx.doi.org/10.2337/db16-0155DOI Listing
October 2016

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ.

Prog Lipid Res 2016 10 22;64:98-122. Epub 2016 Sep 22.

Lee Kong Chian School of Medicine, Nanyang Technological University, Academia, 20 College Road, 169856, Singapore; INRA ToxAlim, UMR1331, Chemin de Tournefeuille, Toulouse Cedex 3, France; Center for Integrative Genomics, University of Lausanne, Le Génopode, CH 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2016.09.001DOI Listing
October 2016

Unraveling the Effects of PPARβ/δ on Insulin Resistance and Cardiovascular Disease.

Trends Endocrinol Metab 2016 05 20;27(5):319-334. Epub 2016 Mar 20.

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Pediatric Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Diagonal 643, 08028 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2016.02.008DOI Listing
May 2016

[Position of Interdisciplinary Spanish Committee for Cardiovascular Prevention about dyslipemia treatment guidelines].

Clin Investig Arterioscler 2015 Jan-Feb;27(1):34-5

Comité editorial de clínica e investigación en arterioesclerosis.

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http://dx.doi.org/10.1016/j.arteri.2014.12.002DOI Listing
February 2016

Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity.

Acta Diabetol 2016 Feb 5;53(1):109-18. Epub 2015 May 5.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00592-015-0759-3DOI Listing
February 2016

AICAR Protects against High Palmitate/High Insulin-Induced Intramyocellular Lipid Accumulation and Insulin Resistance in HL-1 Cardiac Cells by Inducing PPAR-Target Gene Expression.

PPAR Res 2015 16;2015:785783. Epub 2015 Nov 16.

Department of Molecular Genetics, CARIM School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200 MD Maastricht, Netherlands.

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http://dx.doi.org/10.1155/2015/785783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663352PMC
December 2015

[PPARα attenuates palmitate-induced endoplasmic reticulum stress in human cardiac cells by enhancing AMPK activity].

Clin Investig Arterioscler 2014 Nov-Dec;26(6):255-67. Epub 2014 Apr 5.

Departamento de Farmacología y Química Terapéutica, IBUB (Institut de Biomedicina de la Universitat de Barcelona) y CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Facultad de Farmacia, Universitat de Barcelona, Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/j.arteri.2014.02.003DOI Listing
November 2015

Short-term administration of GW501516 improves inflammatory state in white adipose tissue and liver damage in high-fructose-fed mice through modulation of the renin-angiotensin system.

Endocrine 2015 Nov 9;50(2):355-67. Epub 2015 Apr 9.

Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro 87 fds, Rio de Janeiro, 20551-030, Brazil.

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http://link.springer.com/10.1007/s12020-015-0590-1
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http://dx.doi.org/10.1007/s12020-015-0590-1DOI Listing
November 2015

Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.

Clin Sci (Lond) 2015 Nov;129(9):823-37

Department of Pharmacology, School of Pharmacy, University of Granada, 18071 Granada, Spain Instituto de Investigación Biosanitaria de Granada, Granada, Spain

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http://dx.doi.org/10.1042/CS20150111DOI Listing
November 2015

High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents.

Biochim Biophys Acta 2015 Sep 21;1852(9):1687-99. Epub 2015 May 21.

Unitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia, Institut de Biomedicina de la UB (IBUB), Universitat de Barcelona, Barcelona, Spain; Biomedical Research Networking Center in Neurodegenerative Diseases (CIBERNED), Madrid, Spain; Universidad Nacional de Loja, Department of Biotechnology, Ecuador. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439150014
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http://dx.doi.org/10.1016/j.bbadis.2015.05.004DOI Listing
September 2015

miR-146a targets Fos expression in human cardiac cells.

Dis Model Mech 2015 Sep 25;8(9):1081-91. Epub 2015 Jun 25.

Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona) and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy, University of Barcelona, Diagonal 643, Barcelona E-08028, Spain

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http://dx.doi.org/10.1242/dmm.020768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582106PMC
September 2015

Targeting endoplasmic reticulum stress in insulin resistance.

Trends Endocrinol Metab 2015 Aug 12;26(8):438-48. Epub 2015 Jun 12.

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2015.05.007DOI Listing
August 2015

Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.

Am J Physiol Endocrinol Metab 2015 May 24;308(9):E756-69. Epub 2015 Feb 24.

Department of Biochemistry and Molecular Biology, Institut de Biomedicina de la Universitat de Barcelona, Universitat de Barcelona, Barcelona, Spain; Institut de Biomedicina de la Universitat de Barcelona Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain;

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http://ajpendo.physiology.org/content/ajpendo/308/9/E756.ful
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http://ajpendo.physiology.org/content/ajpendo/early/2015/02/
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http://ajpendo.physiology.org/lookup/doi/10.1152/ajpendo.003
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http://dx.doi.org/10.1152/ajpendo.00362.2014DOI Listing
May 2015

PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation.

Biochim Biophys Acta 2015 May 26;1852(5):1049-58. Epub 2015 Feb 26.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry and Institut de Biomedicina de la UB (IBUB), Faculty of Pharmacy, University of Barcelona, Barcelona, Spain; Lee Kong Chian School of Medicine, Nanyang Technological University, The Academia, 20 College Road, 169856, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.02.010DOI Listing
May 2015

PPAR-β/δ activation promotes phospholipid transfer protein expression.

Biochem Pharmacol 2015 Mar 7;94(2):101-8. Epub 2015 Feb 7.

Institut d'Investigacions Biomèdiques (IIB) Sant Pau, Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain; Departament de Bioquímica i Biología Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.01.016DOI Listing
March 2015

Remarkable quantitative and qualitative differences in HDL after niacin or fenofibrate therapy in type 2 diabetic patients.

Atherosclerosis 2015 Feb 9;238(2):213-9. Epub 2014 Dec 9.

Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, Barcelona, Spain; Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), CIBERDEM, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.12.006DOI Listing
February 2015

Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes.

Mediators Inflamm 2013 26;2013:381815. Epub 2013 Dec 26.

Departamento de Farmacobiología, CUCEI, Universidad de Guadalajara, Boulevard Marcelino García Barragán, No. 1421, Esquina Calzada Olímpica, 44430 Guadalajara, JAL, Mexico.

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http://dx.doi.org/10.1155/2013/381815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888727PMC
October 2014

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.

Diabetologia 2014 Oct 26;57(10):2126-35. Epub 2014 Jul 26.

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Diagonal 643, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00125-014-3331-8DOI Listing
October 2014

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.

Biochim Biophys Acta 2014 Sep 2;1842(9):1556-66. Epub 2014 Jun 2.

Unitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia, Institut de Biomedicina de la UB (IBUB), Universitat de Barcelona, Barcelona, Spain; Centros de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Spain; Laboratorio de Regeneración y Desarrollo Neural, Instituto de Neurobiología, Departamento de Biología Celular y Molecular, CUCBA, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.05.025DOI Listing
September 2014

[PPARβ/δ Activation prevents hypertriglyceridemia caused by a high fat diet. Involvement of AMPK and PGC-1α-Lipin1-PPARα pathway].

Clin Investig Arterioscler 2013 Apr-Jun;25(2):63-73. Epub 2013 Feb 22.

Unidad de Farmacología, Departamento de Farmacología y Química Terapéutica e Institut de Biomedicina de la UB IBUB, Facultad de Farmacia, Universidad de Barcelona, Barcelona, España.

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http://dx.doi.org/10.1016/j.arteri.2013.01.001DOI Listing
July 2014

[The problem of familial hypercholesterolemia].

Clin Investig Arterioscler 2013 Sep-Oct;25(4):174

Equipo editorial de Clínica e Investigación en Arteriosclerosis.

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http://dx.doi.org/10.1016/j.arteri.2013.10.001DOI Listing
July 2014

PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells.

Int J Cardiol 2014 Jun 8;174(1):110-8. Epub 2014 Apr 8.

Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona), CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy, University of Barcelona, Diagonal 643, Barcelona E-08028, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2014.03.176DOI Listing
June 2014

An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy.

Int J Cardiol 2013 Oct 6;168(4):3160-72. Epub 2013 Aug 6.

Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona), Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy, University of Barcelona, Diagonal 643, Barcelona E-08028, Spain.

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http://dx.doi.org/10.1016/j.ijcard.2013.07.150DOI Listing
October 2013

Resveratrol induces nuclear factor-κB activity in human cardiac cells.

Int J Cardiol 2013 Sep 27;167(6):2507-16. Epub 2012 Jun 27.

Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona and IBUB, Institut de Biomedicina de la Universitat de Barcelona, 643 Diagonal, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ijcard.2012.06.006DOI Listing
September 2013

Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice.

Biochim Biophys Acta 2013 Aug 16;1832(8):1241-8. Epub 2013 Mar 16.

Unitat de Farmacologia, Department de Farmacologia i Química Terapèutica, Facultat de Farmàcia, Universitat de Barcelona, Institut de Biomedicina de la UB, IBUB, Spain.

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http://dx.doi.org/10.1016/j.bbadis.2013.03.006DOI Listing
August 2013

TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes.

Biochim Biophys Acta 2012 Sep 7;1821(9):1177-85. Epub 2012 Jun 7.

Department of Pharmacology and Therapeutic Chemistry, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2012.05.006DOI Listing
September 2012

Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus.

Expert Opin Ther Targets 2012 Feb 27;16(2):209-23. Epub 2012 Jan 27.

University of Barcelona, Department of Pharmacology and Therapeutic Chemistry, Barcelona, Spain.

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http://www.tandfonline.com/doi/full/10.1517/14728222.2012.65
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http://dx.doi.org/10.1517/14728222.2012.658370DOI Listing
February 2012

The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells.

PLoS One 2011 23;6(5):e19724. Epub 2011 May 23.

Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona) and CIBERDEM, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019724PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100304PMC
November 2011

Liver AMP/ATP ratio and fructokinase expression are related to gender differences in AMPK activity and glucose intolerance in rats ingesting liquid fructose.

J Nutr Biochem 2011 Aug 5;22(8):741-51. Epub 2010 Nov 5.

Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona, IBUB (Institute of Biomedicine University of Barcelona),and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona 08028, Spain.

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http://dx.doi.org/10.1016/j.jnutbio.2010.06.005DOI Listing
August 2011

The Role of Peroxisome Proliferator-Activated Receptor beta/delta on the Inflammatory Basis of Metabolic Disease.

PPAR Res 2010 27;2010. Epub 2010 Jul 27.

Department of Pharmacology and Therapeutic Chemistry, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)-Instituto de Salud Carlos III and Institut de Biomedicina de la Universitat de Barcelona (IBUB), Faculty of Pharmacy, University of Barcelona, Diagonal 643, 08028 Barcelona, Spain.

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http://www.hindawi.com/journals/ppar/2010/368467/
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http://dx.doi.org/10.1155/2010/368467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913795PMC
July 2011

The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation.

Endocrinology 2011 May 1;152(5):1848-59. Epub 2011 Mar 1.

Department of Pharmacology and Therapeutic Chemistry, and Institut de Biomedicina de la University of Barcelona, Barcelona. Spain.

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http://dx.doi.org/10.1210/en.2010-1468DOI Listing
May 2011

PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.

Biochim Biophys Acta 2011 Feb 9;1811(2):59-67. Epub 2010 Nov 9.

Department of Pharmacology and Therapeutic Chemistry, Institut de Biomedicina de la Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2010.11.002DOI Listing
February 2011

The peroxisome proliferator-activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1.

Biochem Pharmacol 2011 Feb 10;81(4):534-43. Epub 2010 Dec 10.

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Institut de Biomedicina de la UB (IBUB), Spain.

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http://dx.doi.org/10.1016/j.bcp.2010.12.004DOI Listing
February 2011

The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells.

Cardiovasc Res 2010 Aug 7;87(3):449-58. Epub 2010 Mar 7.

Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de Universitat de Barcelona)-Instituto de Salud Carlos III, Faculty of Pharmacy, University of Barcelona, Diagonal 643, Barcelona E-08028, Spain.

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http://dx.doi.org/10.1093/cvr/cvq080DOI Listing
August 2010

Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells.

Endocrinology 2010 Feb 18;151(2):537-48. Epub 2009 Dec 18.

Department of Pharmacology and Therapeutic Chemistry and Institut de Biomedicina de la Universitat de Barcelona, Faculty of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1210/en.2009-0874DOI Listing
February 2010

TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model.

Cardiovasc Res 2009 Mar 27;81(4):703-12. Epub 2008 Nov 27.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, IBUB and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)-Instituto de Salud Carlos III, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvn327DOI Listing
March 2009

Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase A.

Hepatology 2009 Jan;49(1):106-15

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)-Instituto de Salud Carlos III, University of Barcelona, Spain.

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http://dx.doi.org/10.1002/hep.22570DOI Listing
January 2009

Peroxisome proliferator-activated receptor (PPAR) beta/delta: a new potential therapeutic target for the treatment of metabolic syndrome.

Curr Mol Pharmacol 2009 Jan;2(1):46-55

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Institut de Biomedicina de la UB University of Barcelona, Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.2174/1874467210902010046DOI Listing
January 2009

Ritonavir increases CD36, ABCA1 and CYP27 expression in THP-1 macrophages.

Exp Biol Med (Maywood) 2008 Dec 10;233(12):1572-82. Epub 2008 Oct 10.

Pharmacology Department, Faculty of Pharmacy and Biomedicine Institute (IBUB), University of Barcelona, and Ciber Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Instituto de Salud Carlos III, Spain.

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http://dx.doi.org/10.3181/0805-RM-144DOI Listing
December 2008

Hepatic gene expression changes in an experimental model of accelerated senescence: the SAM-P8 mouse.

J Gerontol A Biol Sci Med Sci 2008 Oct;63(10):1043-52

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1093/gerona/63.10.1043DOI Listing
October 2008

Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.

Diabetes 2008 Aug 28;57(8):2149-57. Epub 2008 Apr 28.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, Institut de Biomedicina de la UB (IBUB) and CIBERDEM-Instituto de Salud Carlos III, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.2337/db08-0176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494695PMC
August 2008

Monocyte gene-expression profile in men with familial combined hyperlipidemia and its modification by atorvastatin treatment.

Pharmacogenomics 2008 Aug;9(8):1035-54

Pharmacology Department, Faculty of Pharmacy and Biomedicine Institute (IBUB), University of Barcelona and Ciber Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Instituto de Salud Carlos III, Diagonal 643. E-08028, Spain.

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http://dx.doi.org/10.2217/14622416.9.8.1035DOI Listing
August 2008

Atorvastatin inhibits GSK-3beta phosphorylation by cardiac hypertrophic stimuli.

Biochim Biophys Acta 2008 Jan-Feb;1781(1-2):26-35. Epub 2007 Nov 12.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, IBUB (Institut de Biomedicina de la UB) and CIBER Diabetes y Enfermedades Metabólicas, Instituto de Salud Carlos III, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2007.10.009DOI Listing
April 2008

Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells.

J Biol Chem 2008 Apr 14;283(17):11107-16. Epub 2008 Feb 14.

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1074/jbc.M708700200DOI Listing
April 2008

Peroxisome proliferator-activated receptor alpha down-regulation is associated with enhanced ceramide levels in age-associated cardiac hypertrophy.

J Gerontol A Biol Sci Med Sci 2007 Dec;62(12):1326-36

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, and IBUB, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1093/gerona/62.12.1326DOI Listing
December 2007

Hypertriglyceridemia and hepatic steatosis in senescence-accelerated mouse associate to changes in lipid-related gene expression.

J Gerontol A Biol Sci Med Sci 2007 Nov;62(11):1219-27

Department of Pharmacology and Therapeutic Chemistry, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/gerona/62.11.1219DOI Listing
November 2007

Impairment of hepatic Stat-3 activation and reduction of PPARalpha activity in fructose-fed rats.

Hepatology 2007 Mar;45(3):778-88

Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona and IBUB (Institute of Biomedicine University of Barcelona), Barcelona, Spain.

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http://dx.doi.org/10.1002/hep.21499DOI Listing
March 2007

Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite.

Mol Pharmacol 2006 Apr 18;69(4):1174-81. Epub 2006 Jan 18.

Unitat de Farmacologia, Facultat de Farmàcia, Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1124/mol.105.016345DOI Listing
April 2006

Ageing introduces a complex pattern of changes in several rat brain transcription factors depending on gender and anatomical localization.

Exp Gerontol 2006 Apr 4;41(4):372-9. Epub 2006 Apr 4.

Unidad de Farmacología y Farmacognosia, Facultad de Farmacia, Universidad de Barcelona, Avda Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.exger.2006.02.011DOI Listing
April 2006

Peroxisome proliferator-activated receptors and the control of fatty acid oxidation in cardiac hypertrophy.

Mini Rev Med Chem 2006 Mar;6(3):357-63

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.2174/138955706776073457DOI Listing
March 2006

Effects of rosiglitazone and atorvastatin on the expression of genes that control cholesterol homeostasis in differentiating monocytes.

Biochem Pharmacol 2006 Feb 18;71(5):605-14. Epub 2006 Jan 18.

Unitat de Farmacologia, Departament de Farmacologia i Química Terapèutica, Facultat de Farmàcia, Universitat de Barcelona, Av. Diagonal 643. 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2005.11.022DOI Listing
February 2006

Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation.

Endocrinology 2006 Jan 13;147(1):552-61. Epub 2005 Oct 13.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1210/en.2005-0440DOI Listing
January 2006

Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells.

Biochim Biophys Acta 2005 Sep;1736(2):120-7

Unidad de Farmacología, Departamento de Farmacología y Química Terapéutica, Facultad de Farmacia, Universidad de Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2005.08.001DOI Listing
September 2005

Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4.

Br J Pharmacol 2005 Aug;145(7):853-61

1Unidad de Farmacología y Farmacognosia, Facultad de Farmacia, Universidad de Barcelona, Avda. Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1038/sj.bjp.0706260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576214PMC
August 2005

Palmitate-induced interleukin 6 production is mediated by protein kinase C and nuclear-factor kappaB activation and leads to glucose transporter 4 down-regulation in skeletal muscle cells.

Endocrinology 2005 Jul 31;146(7):3087-95. Epub 2005 Mar 31.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1210/en.2004-1560DOI Listing
July 2005

Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration.

Exp Gerontol 2005 Jul;40(7):588-98

Unidad de Farmacología y Farmacognosia, Facultad de Farmacia, Universidad de Barcelona, Spain.

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http://dx.doi.org/10.1016/j.exger.2005.05.006DOI Listing
July 2005

Leptin down-regulates peroxisome proliferator-activated receptor gamma (PPAR-gamma) mRNA levels in primary human monocyte-derived macrophages.

Mol Cell Biochem 2005 Jul;275(1-2):173-9

Unitat de Farmacologia, Departament de Farmacologia i Química Terapèutica, Facultat de Farmàcia, University of Barcelona, Spain.

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http://dx.doi.org/10.1007/s11010-005-1353-8DOI Listing
July 2005

Agonist-induced activation releases peroxisome proliferator-activated receptor beta/delta from its inhibition by palmitate-induced nuclear factor-kappaB in skeletal muscle cells.

Biochim Biophys Acta 2005 May 17;1734(1):52-61. Epub 2005 Mar 17.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2005.02.002DOI Listing
May 2005

Cholesterol regulation of genes involved in sterol trafficking in human THP-1 macrophages.

Mol Cell Biochem 2005 May;273(1-2):185-91

Unitat de Farmacologia, Departament de Farmacologia i Química Terapéutica, Facultat de Farmàcia, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.1007/s11010-005-0624-8DOI Listing
May 2005

Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy.

J Biol Chem 2005 Apr 22;280(17):17464-71. Epub 2005 Feb 22.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1074/jbc.M414220200DOI Listing
April 2005

Aspirin increases CD36, SR-BI, and ABCA1 expression in human THP-1 macrophages.

Cardiovasc Res 2005 Apr 28;66(1):141-9. Epub 2005 Jan 28.

Unitat de Farmacologia, Facultat de Farmacia, Universitat de Barcelona, Nucli Universitari de Pedralbes, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cardiores.2004.12.024DOI Listing
April 2005

Increased Akt protein expression is associated with decreased ceramide content in skeletal muscle of troglitazone-treated mice.

Biochem Pharmacol 2005 Apr;69(8):1195-204

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2005.01.015DOI Listing
April 2005

Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes.

Cardiovasc Res 2005 Mar;65(4):832-41

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cardiores.2004.11.011DOI Listing
March 2005

Atorvastatin improves peroxisome proliferator-activated receptor signaling in cardiac hypertrophy by preventing nuclear factor-kappa B activation.

Biochim Biophys Acta 2005 Feb;1687(1-3):76-83

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2004.11.004DOI Listing
February 2005

Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism.

J Lipid Res 2004 Nov 16;45(11):2015-24. Epub 2004 Aug 16.

Unitat de Farmacologia, Facultat de Farmàcia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1194/jlr.M400049-JLR200DOI Listing
November 2004

Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs.

Biochem Pharmacol 2004 Oct;68(7):1411-21

Unidad de Farmacología y Farmacognosia, Facultad de Farmacia, Universidad de Barcelona Avda Diagonal 643, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2004.06.008DOI Listing
October 2004

Reduction of intracellular cholesterol accumulation in THP-1 macrophages by a combination of rosiglitazone and atorvastatin.

Biochem Pharmacol 2004 Jul;68(1):155-63

Unitat de Farmacologia, Departament de Farmacologia i Química Terapèutica, Facultat de Farmàcia, Universitat de Barcelona, Barcelona 08028, Spain.

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http://dx.doi.org/10.1016/j.bcp.2004.03.009DOI Listing
July 2004

Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages.

Biochem Biophys Res Commun 2004 May;318(1):265-74

Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.021DOI Listing
May 2004