Manuel Irimia

Manuel Irimia

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Manuel Irimia

Publications by authors named "Manuel Irimia"

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Neuronal-specific microexon splicing of mRNA is directly regulated by SRRM4/nSR100.

RNA Biol 2020 Jan 27;17(1):62-74. Epub 2019 Sep 27.

German Cancer Consortium (DKTK) partner site Freiburg, German Cancer Research Center (DKFZ) and Department of Urology, Medical Center-University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1080/15476286.2019.1667214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948980PMC
January 2020

Srrm234, but not canonical SR and hnRNP proteins, drive inclusion of exon 9 variable exons.

RNA 2019 10 10;25(10):1353-1365. Epub 2019 Jul 10.

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

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http://dx.doi.org/10.1261/rna.071316.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800468PMC
October 2019

Retention of paternal DNA methylome in the developing zebrafish germline.

Nat Commun 2019 07 11;10(1):3054. Epub 2019 Jul 11.

Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, NSW, 2010, Australia.

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http://dx.doi.org/10.1038/s41467-019-10895-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624265PMC
July 2019

Origin and evolution of the chordate central nervous system: insights from amphioxus genoarchitecture.

Int J Dev Biol 2017 ;61(10-11-12):655-664

Dept. Genetics, Microbiology and Statistics and Institute of Biomedicine (IBUB), Faculty of Biology, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1387/ijdb.170258jgDOI Listing
January 2019

Matt: Unix tools for alternative splicing analysis.

Bioinformatics 2019 01;35(1):130-132

Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain.

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http://dx.doi.org/10.1093/bioinformatics/bty606DOI Listing
January 2019

Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing.

Mol Cell 2018 11;72(3):496-509.e9

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765183083
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http://dx.doi.org/10.1016/j.molcel.2018.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224609PMC
November 2018

Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture.

Genome Biol 2018 09 17;19(1):135. Epub 2018 Sep 17.

Centre de Regulació Genòmica, Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/s13059-018-1499-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142364PMC
September 2018

Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.

Nature 2018 08;560(7718):E30

Center for Autism Research and Treatment and Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, 90095, USA.

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http://dx.doi.org/10.1038/s41586-018-0295-8DOI Listing
August 2018

RES complex is associated with intron definition and required for zebrafish early embryogenesis.

PLoS Genet 2018 07 3;14(7):e1007473. Epub 2018 Jul 3.

Department of Genetics, Yale University School of Medicine, New Haven, CT, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047831PMC
July 2018

Absence of Tangentially Migrating Glutamatergic Neurons in the Developing Avian Brain.

Cell Rep 2018 01;22(1):96-109

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770341PMC
January 2018

Molecular basis of differential 3' splice site sensitivity to anti-tumor drugs targeting U2 snRNP.

Nat Commun 2017 12 13;8(1):2100. Epub 2017 Dec 13.

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr Aiguader 88, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41467-017-02007-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727392PMC
December 2017

Nodal/Activin Pathway is a Conserved Neural Induction Signal in Chordates.

Nat Ecol Evol 2017 Aug 3;1(8):1192-1200. Epub 2017 Jul 3.

Biologie Intégrative des Organismes Marins (BIOM), Observatoire Océanologique, Sorbonne Universités, UPMC University Paris 06, CNRS, Banyuls-sur-Mer, 66650, France.

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http://dx.doi.org/10.1038/s41559-017-0226-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540175PMC
August 2017

Pica, constipation and cardiorespiratory arrest.

BMJ Case Rep 2017 Jul 14;2017. Epub 2017 Jul 14.

Intensive Care Unit Director, Hospital de Cascais Dr. José de Almeida, Alcabideche, Cascais, Lisboa, Portugal.

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http://dx.doi.org/10.1136/bcr-2017-221066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535214PMC
July 2017

Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.

Cell Rep 2017 03;18(12):2868-2879

Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET) and Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.066DOI Listing
March 2017

Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.

Nature 2016 12 5;540(7633):423-427. Epub 2016 Dec 5.

Center for Autism Research and Treatment and Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature20612DOI Listing
December 2016

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.

Mol Cell 2016 12;64(6):1023-1034

Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.11.033DOI Listing
December 2016

Conserved functional antagonism of CELF and MBNL proteins controls stem cell-specific alternative splicing in planarians.

Elife 2016 08 9;5. Epub 2016 Aug 9.

Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.7554/eLife.16797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978528PMC
August 2016

Complex transcriptional regulation and independent evolution of fungal-like traits in a relative of animals.

Elife 2015 Oct 14;4:e08904. Epub 2015 Oct 14.

Institut de Biologia Evolutiva, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.7554/eLife.08904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739763PMC
October 2015

[Acute respiratory distress syndrome: case series, two years at an intensive care unit].

Acta Med Port 2014 Mar-Apr;27(2):211-7. Epub 2014 Apr 30.

Unidade de Cuidados Intensivos. Hospital de Cascais Dr José de Almeida. Cascais. Portugal.

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August 2015

An alternative splicing event amplifies evolutionary differences between vertebrates.

Science 2015 Aug;349(6250):868-73

Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada. Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1126/science.aaa8381DOI Listing
August 2015

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.

Genes Dev 2015 Apr;29(7):746-59

Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada;

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http://dx.doi.org/10.1101/gad.256115.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387716PMC
April 2015

Widespread intron retention in mammals functionally tunes transcriptomes.

Genome Res 2014 Nov 25;24(11):1774-86. Epub 2014 Sep 25.

Donnelly Centre, University of Toronto, Ontario, M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Ontario, M5S 1A8, Canada;

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http://dx.doi.org/10.1101/gr.177790.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216919PMC
November 2014

Stability depends on positive autoregulation in Boolean gene regulatory networks.

PLoS Comput Biol 2014 Nov 6;10(11):e1003916. Epub 2014 Nov 6.

Department of Biology, Stanford University, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222607PMC
November 2014

Diversity and evolution of spliceosomal systems.

Methods Mol Biol 2014 ;1126:13-33

Department of Biology, San Francisco State University, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-62703-980-2_2DOI Listing
October 2014

A global regulatory mechanism for activating an exon network required for neurogenesis.

Mol Cell 2014 Oct 11;56(1):90-103. Epub 2014 Sep 11.

Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608043PMC
October 2014

Origin of spliceosomal introns and alternative splicing.

Cold Spring Harb Perspect Biol 2014 Jun 2;6(6). Epub 2014 Jun 2.

Department of Biology, San Francisco State University, San Francisco, California 94132.

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http://dx.doi.org/10.1101/cshperspect.a016071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031966PMC
June 2014

MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation.

Nat Commun 2013 ;4:2480

1] CNRS, Institut de Génétique Moléculaire de Montpellier, Montpellier F-34293, France [2] Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK [3] Université Montpellier 2, F-34293 Montpellier cedex 5, France [4] Université Montpellier 1, F-34094 Montpellier cedex 5, France [5].

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http://dx.doi.org/10.1038/ncomms3480DOI Listing
April 2014

Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.

Sci Rep 2014 Apr 11;4:4655. Epub 2014 Apr 11.

1] Donnelly Centre for Cellular & Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada [2] Bioinformatics Research Laboratory, Department of Biological Sciences, University of Cyprus, PO Box 20537, CY-1678 Nicosia, Cyprus [3] Institute of Applied Biosciences, Centre for Research & Technology, PO Box 361, GR-57001 Thessalonica, Greece [4].

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http://www.nature.com/articles/srep04655
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http://dx.doi.org/10.1038/srep04655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983603PMC
April 2014

Deep conservation of cis-regulatory elements in metazoans.

Philos Trans R Soc Lond B Biol Sci 2013 Dec 11;368(1632):20130020. Epub 2013 Nov 11.

Department of Zoology, University of Oxford, , Oxford, UK.

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http://dx.doi.org/10.1098/rstb.2013.0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826494PMC
December 2013

Regulated aggregative multicellularity in a close unicellular relative of metazoa.

Elife 2013 Dec 24;2:e01287. Epub 2013 Dec 24.

Department of Functional Genomics and Evolution, Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona, Spain.

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http://dx.doi.org/10.7554/eLife.01287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870316PMC
December 2013

Ancient cis-regulatory constraints and the evolution of genome architecture.

Trends Genet 2013 Sep 18;29(9):521-8. Epub 2013 Jun 18.

The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.tig.2013.05.008DOI Listing
September 2013

Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties.

Sci Rep 2012 31;2:433. Epub 2012 May 31.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/srep00433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364491PMC
February 2013

Impact of gene gains, losses and duplication modes on the origin and diversification of vertebrates.

Semin Cell Dev Biol 2013 Feb 3;24(2):83-94. Epub 2013 Jan 3.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Av. Diagonal 645, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.semcdb.2012.12.008DOI Listing
February 2013

Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression.

BMC Genomics 2012 Dec 19;13:713. Epub 2012 Dec 19.

Centro Andaluz de Biología del Desarrollo (CABD), CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Ctra. Utrera Km 1, Seville 41013, Spain.

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http://dx.doi.org/10.1186/1471-2164-13-713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541358PMC
December 2012

Widespread recurrent evolution of genomic features.

Genome Biol Evol 2012 13;4(4):486-500. Epub 2012 Mar 13.

Department of Zoology, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/gbe/evs022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342872PMC
July 2012

Genome evolution: where do new introns come from?

Curr Biol 2012 Jul;22(13):R529-31

Department of Biology, 1600 Holloway Avenue, San Francisco State University, San Francisco, CA 94132, USA.

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http://dx.doi.org/10.1016/j.cub.2012.05.017DOI Listing
July 2012

Alternative splicing: decoding an expansive regulatory layer.

Curr Opin Cell Biol 2012 Jun 30;24(3):323-32. Epub 2012 Mar 30.

Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.ceb.2012.03.005DOI Listing
June 2012

Tissue-specific alternative splicing remodels protein-protein interaction networks.

Mol Cell 2012 Jun;46(6):884-92

Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada.

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http://dx.doi.org/10.1016/j.molcel.2012.05.037DOI Listing
June 2012

Evolutionarily conserved A-to-I editing increases protein stability of the alternative splicing factor Nova1.

RNA Biol 2012 Jan 1;9(1):12-21. Epub 2012 Jan 1.

Departament de Genètica, Facultat de Biología, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.4161/rna.9.1.18387DOI Listing
January 2012

Transphyletic conservation of developmental regulatory state in animal evolution.

Proc Natl Acad Sci U S A 2011 Aug 15;108(34):14186-91. Epub 2011 Aug 15.

Centro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Cientificas - Universidad Pablo de Olavide, E-41013 Sevilla, Spain.

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http://dx.doi.org/10.1073/pnas.1109037108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161536PMC
August 2011

Internal and external paralogy in the evolution of tropomyosin genes in metazoans.

Mol Biol Evol 2010 Jul 10;27(7):1504-17. Epub 2010 Feb 10.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/molbev/msq018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912468PMC
July 2010

Complex selection on 5' splice sites in intron-rich organisms.

Genome Res 2009 Nov 10;19(11):2021-7. Epub 2009 Sep 10.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1101/gr.089276.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775602PMC
November 2009

Splicing in the eukaryotic ancestor: form, function and dysfunction.

Trends Ecol Evol 2009 Aug 1;24(8):447-55. Epub 2009 Jul 1.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Medicine, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016953470900174
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http://dx.doi.org/10.1016/j.tree.2009.04.005DOI Listing
August 2009

Mystery of intron gain: new data and new models.

Trends Genet 2009 Feb 11;25(2):67-73. Epub 2008 Dec 11.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016895250800313
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http://dx.doi.org/10.1016/j.tig.2008.11.004DOI Listing
February 2009

Quantitative regulation of alternative splicing in evolution and development.

Bioessays 2009 Jan;31(1):40-50

Departament de Genètica, and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/bies.080092DOI Listing
January 2009

Gene expansion and retention leads to a diverse tyrosine kinase superfamily in amphioxus.

Mol Biol Evol 2008 Sep 11;25(9):1841-54. Epub 2008 Jun 11.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/molbev/msn132DOI Listing
September 2008

Convergent evolution of clustering of Iroquois homeobox genes across metazoans.

Mol Biol Evol 2008 Aug 9;25(8):1521-5. Epub 2008 May 9.

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http://dx.doi.org/10.1093/molbev/msn109DOI Listing
August 2008

Origin of introns by 'intronization' of exonic sequences.

Trends Genet 2008 Aug 1;24(8):378-81. Epub 2008 Jul 1.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Barcelona 08028, Spain.

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http://dx.doi.org/10.1016/j.tig.2008.05.007DOI Listing
August 2008

Evolutionary convergence on highly-conserved 3' intron structures in intron-poor eukaryotes and insights into the ancestral eukaryotic genome.

PLoS Genet 2008 Aug 8;4(8):e1000148. Epub 2008 Aug 8.

Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1371/journal.pgen.1000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483917PMC
August 2008

Origins of human malaria: rare genomic changes and full mitochondrial genomes confirm the relationship of Plasmodium falciparum to other mammalian parasites but complicate the origins of Plasmodium vivax.

Mol Biol Evol 2008 Jun 21;25(6):1192-8. Epub 2008 Mar 21.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/molbev/msn069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386083PMC
June 2008

When good transcripts go bad: artifactual RT-PCR 'splicing' and genome analysis.

Bioessays 2008 Jun;30(6):601-5

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

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http://dx.doi.org/10.1002/bies.20749DOI Listing
June 2008

Intron mis-splicing: no alternative?

Genome Biol 2008 19;9(2):208. Epub 2008 Feb 19.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1186/gb-2008-9-2-208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374719PMC
May 2008

Rare genomic characters do not support Coelomata: intron loss/gain.

Mol Biol Evol 2008 Apr 14;25(4):620-3. Epub 2008 Feb 14.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msn035DOI Listing
April 2008

Spliceosomal introns as tools for genomic and evolutionary analysis.

Nucleic Acids Res 2008 Mar 7;36(5):1703-12. Epub 2008 Feb 7.

Departament de Genètica, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/nar/gkn012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275149PMC
March 2008

Rare genomic characters do not support Coelomata: RGC_CAMs.

J Mol Evol 2008 Mar 5;66(3):308-15. Epub 2008 Mar 5.

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http://link.springer.com/10.1007/s00239-008-9077-5
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http://dx.doi.org/10.1007/s00239-008-9077-5DOI Listing
March 2008

Widespread evolutionary conservation of alternatively spliced exons in Caenorhabditis.

Mol Biol Evol 2008 Feb 28;25(2):375-82. Epub 2007 Nov 28.

Departament de Genètica, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/molbev/msm262DOI Listing
February 2008

Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing.

BMC Evol Biol 2007 Oct 4;7:188. Epub 2007 Oct 4.

Allan Wilson Centre for Molecular Evolution and Ecology, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.1186/1471-2148-7-188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082043PMC
October 2007

Rare coding sequence changes are consistent with Ecdysozoa, not Coelomata.

Mol Biol Evol 2007 Aug 24;24(8):1604-7. Epub 2007 May 24.

Departament de Genètica, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/molbev/msm105DOI Listing
August 2007

Coevolution of genomic intron number and splice sites.

Trends Genet 2007 Jul 18;23(7):321-5. Epub 2007 Apr 18.

Allan Wilson Centre for Molecular Evolution and Ecology, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.tig.2007.04.001DOI Listing
July 2007

High qualitative and quantitative conservation of alternative splicing in Caenorhabditis elegans and Caenorhabditis briggsae.

Mol Biol Evol 2007 Apr 1;24(4):909-17. Epub 2007 Feb 1.

Molecular Evolution Group, Department of Molecular Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1093/molbev/msm023DOI Listing
April 2007

Very little intron gain in Entamoeba histolytica genes laterally transferred from prokaryotes.

Mol Biol Evol 2006 Oct 17;23(10):1824-7. Epub 2006 Jul 17.

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http://dx.doi.org/10.1093/molbev/msl061DOI Listing
October 2006

CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer.

Oncogene 2004 Nov;23(53):8695-9

Molecular Pathology Program, Cancer Epigenetics Laboratory, Spanish National Cancer Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain.

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http://dx.doi.org/10.1038/sj.onc.1207914DOI Listing
November 2004