Manuel Baca

Manuel Baca

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Manuel Baca

Manuel Baca

Publications by authors named "Manuel Baca"

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33Publications

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Characterizing the Overall Derivatization of Conjugated Oligomeric Proteins.

PDA J Pharm Sci Technol 2017 Mar-Apr;71(2):115-126. Epub 2017 Mar 13.

Department of Nonclinical Biostatistics,

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http://dx.doi.org/10.5731/pdajpst.2016.006510DOI Listing
June 2018

Crystal structure of the human 4-1BB/4-1BBL complex.

J Biol Chem 2018 06 2;293(25):9880-9891. Epub 2018 May 2.

From the Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland 20878

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http://www.jbc.org/lookup/doi/10.1074/jbc.RA118.002803
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http://dx.doi.org/10.1074/jbc.RA118.002803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016478PMC
June 2018

A hingeless Fc fusion system for site-specific cleavage by IdeS.

MAbs 2016 Aug-Sep;8(6):1118-25. Epub 2016 May 21.

a Department of Antibody Discovery and Protein Engineering , MedImmune LLC , Gaithersburg , MD , USA.

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http://www.tandfonline.com/doi/full/10.1080/19420862.2016.11
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http://dx.doi.org/10.1080/19420862.2016.1186321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968090PMC
December 2017

Impact of Mutations on the Higher Order Structure and Activity of a Recombinant Uricase.

J Pharm Sci 2017 04 4;106(4):1018-1024. Epub 2017 Jan 4.

Analytical Sciences, MedImmune, Gaithersburg, Maryland 20878.

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http://dx.doi.org/10.1016/j.xphs.2016.12.028DOI Listing
April 2017

Combining phage display with de novo protein sequencing for reverse engineering of monoclonal antibodies.

MAbs 2016 ;8(3):501-12

a Department of Antibody Discovery and Protein Engineering , MedImmune, LLC , Gaithersburg , MD , USA.

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http://dx.doi.org/10.1080/19420862.2016.1145865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966834PMC
December 2016

Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors.

J Control Release 2016 07 17;234:104-14. Epub 2016 May 17.

Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1016/j.jconrel.2016.05.041DOI Listing
July 2016

Enhanced catalysis of oxime-based bioconjugations by substituted anilines.

Bioconjug Chem 2014 Jan 17;25(1):93-101. Epub 2013 Dec 17.

Department of Purification Process Sciences and ‡Department of Antibody Discovery and Protein Engineering, MedImmune, LLC , Gaithersburg, Maryland 20878, United States.

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http://dx.doi.org/10.1021/bc400380fDOI Listing
January 2014

O-xylosylation in a recombinant protein is directed at a common motif on glycine-serine linkers.

J Pharm Sci 2013 Nov 19;102(11):3920-4. Epub 2013 Sep 19.

Analytical Biochemistry, MedImmune LLC, Gaithersburg, Maryland.

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https://linkinghub.elsevier.com/retrieve/pii/S00223549153082
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http://dx.doi.org/10.1002/jps.23733DOI Listing
November 2013

Fibronectin type III domains engineered to bind CD40L: cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of two complexes.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Sep 21;69(Pt 9):1045-8. Epub 2013 Aug 21.

Department of Antibody Discovery and Protein Engineering, MedImmune, One MedImmune Way, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1107/S1744309113022847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758160PMC
September 2013

Multivalent scaffold proteins as superagonists of TRAIL receptor 2-induced apoptosis.

Mol Cancer Ther 2013 Jul 3;12(7):1235-44. Epub 2013 May 3.

Department of Antibody Discovery and Protein Engineering, MedImmune, LLC, One MedImmune Way, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-1107DOI Listing
July 2013

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production.

Am J Respir Cell Mol Biol 2008 Dec 10;39(6):739-46. Epub 2008 Jul 10.

Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8057, USA.

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http://dx.doi.org/10.1165/rcmb.2008-0053OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586049PMC
December 2008

Confinement in nanopores at the oxide/water interface: modification of alumina adsorption properties.

Chemistry 2008 ;14(20):6142-8

UPMC Univ Paris 06, UMR 7609, Laboratoire de Réactivité de Surface, 75005, Paris, France.

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http://dx.doi.org/10.1002/chem.200800032DOI Listing
September 2008

Affinity purification of interacting proteins from cell lysates.

CSH Protoc 2007 Feb 1;2007:pdb.prot4593. Epub 2007 Feb 1.

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http://dx.doi.org/10.1101/pdb.prot4593DOI Listing
February 2007

The biology of vascular endothelial growth factor-B (VEGF-B).

Pulm Pharmacol Ther 2006 25;19(1):61-9. Epub 2005 Apr 25.

Amrad Corporation Ltd, Biologicals Research Group, 576 Swan St, Richmond, Vic. 3121, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S109455390500039
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http://dx.doi.org/10.1016/j.pupt.2005.02.007DOI Listing
May 2006

Identification of the key LMO2-binding determinants on Ldb1.

J Mol Biol 2006 May 20;359(1):66-75. Epub 2006 Mar 20.

School of Molecular and Microbial Biosciences, University of Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.jmb.2006.02.074DOI Listing
May 2006

What coaching methods work best with employees?

MGMA Connex 2005 Nov-Dec;5(10):12

Los Alamos NM Medical Care Clinic, USA.

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February 2006

Direct production of proteins with N-terminal cysteine for site-specific conjugation.

Bioconjug Chem 2004 May-Jun;15(3):658-63

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1021/bc049965oDOI Listing
December 2004

Analysis of SH2 ligands and identification of sites of interaction.

Authors:
Manuel Baca

Methods Mol Biol 2004 ;249:111-20

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1385/1-59259-667-3:111DOI Listing
February 2004

Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.

J Biol Chem 2004 Jan 29;279(3):2125-34. Epub 2003 Oct 29.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1074/jbc.M310103200DOI Listing
January 2004

A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol).

Biochemistry 2003 Nov;42(45):13193-201

The Walter and Eliza Hall Institute of Medical Research, The Cooperative Research Centre for Cellular Growth Factors, Parkville, Victoria 3050, Australia.

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http://pubs.acs.org/doi/abs/10.1021/bi035303v
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http://dx.doi.org/10.1021/bi035303vDOI Listing
November 2003

Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.

Biochem J 2003 Jun;372(Pt 2):495-502

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1042/BJ20030104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223392PMC
June 2003

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

J Biol Chem 2002 Oct 2;277(43):40181-4. Epub 2002 Sep 2.

Walter and Eliza Hall Institute of Medical Research and the Cooperative Research for Cellular Growth Factors, PO Royal Melbourne Hospital, VIC 3050, Australia.

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http://dx.doi.org/10.1074/jbc.C200450200DOI Listing
October 2002

A fusion protein system for the recombinant production of short disulfide-containing peptides.

Protein Expr Purif 2002 Oct;26(1):171-8

The Walter and Eliza Hall Institute of Medical Research, and The Cooperative Research Centre for Cellular Growth Factors, Post Office, Royal Melbourne Hospital, 3050, Parkville, Vic., Australia.

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http://dx.doi.org/10.1016/s1046-5928(02)00521-1DOI Listing
October 2002

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities.

Biochemistry 2002 Jul;41(29):9229-36

The Walter and Eliza Hall Institute of Medical Research, and The Cooperative Research Centre for Cellular Growth Factors, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1021/bi0259507DOI Listing
July 2002