Manuel A Friese

Manuel A Friese

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Manuel A Friese

Manuel A Friese

Publications by authors named "Manuel A Friese"

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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 Aug 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

Pregnancy Enables Expansion of Disease-Specific Regulatory T Cells in an Animal Model of Multiple Sclerosis.

J Immunol 2019 Aug 23. Epub 2019 Aug 23.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, 20251 Hamburg, Germany;

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http://dx.doi.org/10.4049/jimmunol.1900611DOI Listing
August 2019

Bassoon proteinopathy drives neurodegeneration in multiple sclerosis.

Nat Neurosci 2019 06 22;22(6):887-896. Epub 2019 Apr 22.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41593-019-0385-4DOI Listing
June 2019

Arc/Arg3.1 defines dendritic cells and Langerhans cells with superior migratory ability independent of phenotype and ontogeny in mice.

Eur J Immunol 2019 May 6;49(5):724-736. Epub 2019 Mar 6.

Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/eji.201847797DOI Listing
May 2019

Sex differences in autoimmune disorders of the central nervous system.

Semin Immunopathol 2019 Mar 25;41(2):177-188. Epub 2018 Oct 25.

Institute of Neuroimmunology and Multiple Sclerosis (INIMS), Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00281-018-0723-8DOI Listing
March 2019

Progesterone modulates the T-cell response via glucocorticoid receptor-dependent pathways.

Am J Reprod Immunol 2019 Feb 28;81(2):e13084. Epub 2019 Jan 28.

Department of Obstetrics and Fetal Medicine, Laboratory for Experimental, Feto-Maternal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/aji.13084DOI Listing
February 2019

Human Fetal TNF-α-Cytokine-Producing CD4 Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life.

Immunity 2019 02 12;50(2):462-476.e8. Epub 2019 Feb 12.

Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam University Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands; Department of Pediatrics, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20251, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183053
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http://dx.doi.org/10.1016/j.immuni.2018.12.010DOI Listing
February 2019

Production of IL-17 by MAIT Cells Is Increased in Multiple Sclerosis and Is Associated with IL-7 Receptor Expression.

J Immunol 2018 02 3;200(3):974-982. Epub 2018 Jan 3.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, 20251 Hamburg, Germany

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1701213
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http://dx.doi.org/10.4049/jimmunol.1701213DOI Listing
February 2018

Ruxolitinib treatment in a patient with neuromyelitis optica: A case report.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 3;4(2):e328. Epub 2017 Feb 3.

Institute for Neuroimmunology and Multiple Sclerosis (S.C.H., J.-P.S., S.C.R., K.Y., M.A.F., C.H.), Department of Neurology (S.C.H., J.-P.S., S.C.R., K.Y., C.H.), and Department of Diagnostic and Interventional Neuroradiology (B.H.), University Medical Center Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292926PMC
March 2017

Maraviroc as possible treatment for PML-IRIS in natalizumab-treated patients with MS.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 8;4(2):e325. Epub 2017 Feb 8.

Institute of Neuroimmunology and Multiple Sclerosis (S.C.H., K.H.S., M.A.F., C.H.), Department of Neurology (S.C.H., K.H.S., C.H.), and Department of Diagnostic and Interventional Neuroradiology (B.H.), University Medical Center Hamburg-Eppendorf; and Neurological Private Practice (V.B., B.E.), Hamburg, Germany.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299629PMC
March 2017

Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy.

Proc Natl Acad Sci U S A 2017 01 3;114(2):E181-E190. Epub 2017 Jan 3.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, 20251 Hamburg, Germany;

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http://dx.doi.org/10.1073/pnas.1617115114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240705PMC
January 2017

Activity of Na1.2 promotes neurodegeneration in an animal model of multiple sclerosis.

JCI Insight 2016 11 17;1(19):e89810. Epub 2016 Nov 17.

Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1172/jci.insight.89810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111507PMC
November 2016

Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation.

Sci Immunol 2016 Sep;1(3):eaaf8665

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, 20251 Hamburg, Germany.

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http://dx.doi.org/10.1126/sciimmunol.aaf8665DOI Listing
September 2016

Sex effects on inflammatory and neurodegenerative processes in multiple sclerosis.

Neurosci Biobehav Rev 2016 Aug 8;67:137-46. Epub 2016 Jan 8.

Institute of Neuroimmunology and Multiple Sclerosis (INIMS), Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg Eppendorf, Hamburg, Germany; Center for Neurology, Neurosurgery and Psychiatry, Department of Psychiatry, Campus Benjamin Franklin, Charité Universitätsmedizin Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2015.12.015DOI Listing
August 2016

Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor.

Neurol Neuroimmunol Neuroinflamm 2016 Aug 17;3(4):e241. Epub 2016 May 17.

Institute of Clinical Neuroimmunology (G.R., A.G.N., K.S., R.H., K.D.) and Munich Cluster for Systems Neurology (SyNergy) (R.H., K.D.), Ludwig-Maximilian-University, Munich; Department of Life Sciences (A.P., M.K., I.A.), Technical University Munich, Freising; Max Planck Institute of Biochemistry (S.P.), Martinsried; Institute of Neuroimmunology and Multiple Sclerosis (M.A.F.), University Medical Centre, Hamburg-Eppendorf, Hamburg, Germany; MRC Human Immunology Unit (K.E.A.), Radcliffe Department of Medicine, Weatherall, Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, UK; and Center for Integrated Protein Science Munich (CIPSM) (I.A.), Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871805PMC
August 2016

Plasticity of Th17 Cells in Autoimmune Kidney Diseases.

J Immunol 2016 07 6;197(2):449-57. Epub 2016 Jun 6.

III. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany;

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http://dx.doi.org/10.4049/jimmunol.1501831DOI Listing
July 2016

Widespread synaptic loss in multiple sclerosis.

Authors:
Manuel A Friese

Brain 2016 Jan;139(Pt 1):2-4

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

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http://dx.doi.org/10.1093/brain/awv349DOI Listing
January 2016

Multiple sclerosis associated genetic variants of CD226 impair regulatory T cell function.

Brain 2015 Nov 10;138(Pt 11):3263-74. Epub 2015 Sep 10.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1093/brain/awv256DOI Listing
November 2015

Immunopathology of multiple sclerosis.

Nat Rev Immunol 2015 Sep 7;15(9):545-58. Epub 2015 Aug 7.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1038/nri3871DOI Listing
September 2015

Acquired channelopathies as contributors to development and progression of multiple sclerosis.

Exp Neurol 2014 Dec 20;262 Pt A:28-36. Epub 2014 Mar 20.

Zentrum für Molekulare Neurobiologie, Universitätsklinikum Hamburg-Eppendorf, Falkenried 94, D-20251 Hamburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144886130037
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http://dx.doi.org/10.1016/j.expneurol.2013.12.006DOI Listing
December 2014

Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke.

Stroke 2014 Nov 18;45(11):3395-402. Epub 2014 Sep 18.

From the Department of Neurology (M. Gelderblom, P.A., C.G., T.M.), Institute of Neuroimmunology and Multiple Sclerosis (B.S., F.U., M.A.F.), and Institute of Neuropathology (C.B., M. Glatzel), University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Neurology, University of Muenster, Muenster, Germany (N.M., G.H., S.B., A.M.H., S.G.M.); and Department of Neurology, University Clinics Wuerzburg, Wuerzburg, Germany (E.G., C.K.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005836DOI Listing
November 2014

CD8⁺ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis.

Eur J Immunol 2014 Oct 19;44(10):3119-28. Epub 2014 Aug 19.

Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/eji.201344160DOI Listing
October 2014

A vaccine targeting mutant IDH1 induces antitumour immunity.

Nature 2014 Aug 25;512(7514):324-7. Epub 2014 Jun 25.

1] Department of Neurooncology, University Hospital Heidelberg and National Center for Tumor Diseases, 69120 Heidelberg, Germany [2] German Cancer Consortium (DKTK) Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature13387DOI Listing
August 2014

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis.

Nat Rev Neurol 2014 Apr 18;10(4):225-38. Epub 2014 Mar 18.

Nuffield Department of Clinical Neurosciences and Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

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http://www.nature.com/articles/nrneurol.2014.37
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http://dx.doi.org/10.1038/nrneurol.2014.37DOI Listing
April 2014

Neutrophils amplify autoimmune central nervous system infiltrates by maturing local APCs.

J Immunol 2013 Nov 23;191(9):4531-9. Epub 2013 Sep 23.

Zentrum für Molekulare Neurobiologie, Universitätsklinikum Hamburg-Eppendorf, D-20251 Hamburg, Germany.

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http://dx.doi.org/10.4049/jimmunol.1202613DOI Listing
November 2013

A clinical and neurobiological case of IgM NMDA receptor antibody associated encephalitis mimicking bipolar disorder.

Psychiatry Res 2013 Jul 13;208(2):194-6. Epub 2012 Dec 13.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20253 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.psychres.2012.09.035DOI Listing
July 2013

Pregnancy and multiple sclerosis: feto-maternal immune cross talk and its implications for disease activity.

J Reprod Immunol 2013 Mar;97(1):140-6

Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jri.2012.10.005DOI Listing
March 2013

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

Nat Med 2012 Dec 18;18(12):1805-11. Epub 2012 Nov 18.

Forschergruppe Neuroimmunologie, Zentrum für Molekulare Neurobiologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://www.nature.com/articles/nm.3015
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http://dx.doi.org/10.1038/nm.3015DOI Listing
December 2012

CD8-mediated inflammatory central nervous system disorders.

Curr Opin Neurol 2012 Jun;25(3):316-21

Institut für Neuroimmunologie und Klinische MS-Forschung, Zentrum für Molekulare Neurobiologie, Universitätsklinikum Hamburg-Eppendorf, Falkenried, Hamburg, Germany.

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https://insights.ovid.com/crossref?an=00019052-201206000-000
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http://dx.doi.org/10.1097/WCO.0b013e328352ea8bDOI Listing
June 2012

Multiple enlarged nerves on neurosonography: an unusual paraneoplastic case.

Muscle Nerve 2011 May;43(5):756-8

Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1002/mus.22010DOI Listing
May 2011

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.

Acta Crystallogr D Biol Crystallogr 2011 May 13;67(Pt 5):447-54. Epub 2011 Apr 13.

Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX39DS, England.

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http://dx.doi.org/10.1107/S0907444911007888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087623PMC
May 2011

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.

Brain 2011 Feb 13;134(Pt 2):571-84. Epub 2011 Jan 13.

Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/brain/awq337DOI Listing
February 2011

IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain.

Am J Pathol 2011 Feb;178(2):794-802

Department of Neuropathology, Weatherall Institute of Molecular Medicine, Oxford Radcliffe NHS Trust, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.ajpath.2010.10.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032888PMC
February 2011

Pathogenic CD8(+) T cells in multiple sclerosis.

Ann Neurol 2009 Aug;66(2):132-41

Institut für Neuroimmunologie und Klinische Multiple Sklerose-Forschung, Zentrum für Molekulare Neurobiologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/ana.21744DOI Listing
August 2009

From genes to function: the next challenge to understanding multiple sclerosis.

Nat Rev Immunol 2009 Jun;9(6):408-17

Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1038/nri2554DOI Listing
June 2009

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

Nat Med 2008 Nov 26;14(11):1227-35. Epub 2008 Oct 26.

Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Headley Way, Oxford, UK.

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http://dx.doi.org/10.1038/nm.1881DOI Listing
November 2008

Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.

Nat Med 2007 Dec 11;13(12):1483-9. Epub 2007 Nov 11.

Medical Research Council Human Immunology Unit and Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

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http://www.nature.com/articles/nm1668
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http://dx.doi.org/10.1038/nm1668DOI Listing
December 2007

T cells and microglia as drivers of multiple sclerosis pathology.

Brain 2007 Nov;130(Pt 11):2755-7

Department of Clinical Neurology and MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1093/brain/awm246DOI Listing
November 2007

Humanized mouse models for organ-specific autoimmune diseases.

Curr Opin Immunol 2006 Dec 27;18(6):704-9. Epub 2006 Sep 27.

MRC Human Immunology Unit and Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1016/j.coi.2006.09.003DOI Listing
December 2006

TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells.

Brain 2006 Sep 3;129(Pt 9):2416-25. Epub 2006 Aug 3.

Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1093/brain/awl205DOI Listing
September 2006

The value of animal models for drug development in multiple sclerosis.

Brain 2006 Aug 24;129(Pt 8):1940-52. Epub 2006 Apr 24.

MRC Human Immunology Unit and Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1093/brain/awl083DOI Listing
August 2006

MHC II molecules in inflammatory diseases: interplay of qualities and quantities.

Trends Immunol 2005 Nov 31;26(11):559-61. Epub 2005 Aug 31.

MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1016/j.it.2005.08.011DOI Listing
November 2005

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

Brain 2005 Aug 23;128(Pt 8):1747-63. Epub 2005 Jun 23.

MRC Human Immunology Unit and Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1093/brain/awh578DOI Listing
August 2005

HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: implications for immune escape in vivo.

J Neuropathol Exp Neurol 2005 Jun;64(6):523-8

Laboratory of Molecular Neuro-Oncology, Department of General Neurology, Hertie Institute for ClinicaI Brain Research, University of Tübingen Medical School, Tübingen, Germany.

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http://dx.doi.org/10.1093/jnen/64.6.523DOI Listing
June 2005

Multiple sclerosis: MHC associations and therapeutic implications.

Expert Rev Mol Med 2005 Feb 14;7(3):1-17. Epub 2005 Feb 14.

Division of Structural Biology, The Henry Wellcome Building for Genomic Medicine, The University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1017/S1462399405008914DOI Listing
February 2005

RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.

Cancer Res 2004 Oct;64(20):7596-603

Department of General Neurology, Hertie Institute for Clinical Brain Research and Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1627DOI Listing
October 2004

MICA/NKG2D-mediated immunogene therapy of experimental gliomas.

Cancer Res 2003 Dec;63(24):8996-9006

Department of Neurology, University of Tübingen, Tübingen, Germany.

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December 2003

Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H.

J Immunol 2002 Dec;169(12):6935-44

Department of Bacteriology and Immunology, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.4049/jimmunol.169.12.6935DOI Listing
December 2002