Publications by authors named "Manu Vanaerschot"

40Publications

Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery.

Cell Chem Biol 2020 Feb 5;27(2):158-171.e3. Epub 2019 Dec 5.

Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031696PMC
February 2020

Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors.

J Am Chem Soc 2018 09 29;140(36):11424-11437. Epub 2018 Aug 29.

Department of Pathology and Microbiology , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.

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http://pubs.acs.org/doi/10.1021/jacs.8b06656
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http://dx.doi.org/10.1021/jacs.8b06656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407133PMC
September 2018

Alice in microbes' land: adaptations and counter-adaptations of vector-borne parasitic protozoa and their hosts.

FEMS Microbiol Rev 2016 09 10;40(5):664-85. Epub 2016 Jul 10.

Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, B-2000 Antwerp, Belgium University of Antwerp, Department of Biomedical Sciences, Laboratory of Microbiology, Parasitology and Health, Universiteitsplein 1, B-2610 Wilrijk, Belgium

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http://dx.doi.org/10.1093/femsre/fuw018DOI Listing
September 2016

Antileishmanial activity of a series of N²,N⁴-disubstituted quinazoline-2,4-diamines.

J Med Chem 2014 Jun 17;57(12):5141-56. Epub 2014 Jun 17.

Department of Chemistry, University of South Florida , 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States.

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http://dx.doi.org/10.1021/jm5000408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216219PMC
June 2014

Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype?

Expert Rev Anti Infect Ther 2014 Aug 6;12(8):937-46. Epub 2014 May 6.

Molecular Parasitology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerpen, Belgium.

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http://www.tandfonline.com/doi/full/10.1586/14787210.2014.91
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http://dx.doi.org/10.1586/14787210.2014.916614DOI Listing
August 2014

Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure.

Mol Microbiol 2013 Oct 11;90(2):428-42. Epub 2013 Sep 11.

Unit of Molecular Parasitology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1111/mmi.12374DOI Listing
October 2013

In vitro susceptibility of Leishmania donovani to miltefosine in Indian visceral leishmaniasis.

Am J Trop Med Hyg 2013 Oct 26;89(4):750-4. Epub 2013 Aug 26.

Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, UP, India; Unit of Epidemiology and Control of Tropical Diseases, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Pathology, Indian Council of Medical Research, Safdarjung Hospital Campus, New Delhi, India; Unit of Molecular Parasitology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium; Department of Biomedical Sciences, Antwerp University, Antwerp, Belgium.

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http://dx.doi.org/10.4269/ajtmh.13-0096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795107PMC
October 2013

Reply to Das.

Clin Infect Dis 2013 Nov 13;57(9):1365-6. Epub 2013 Aug 13.

Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1093/cid/cit510DOI Listing
November 2013

Drug resistance in vectorborne parasites: multiple actors and scenarios for an evolutionary arms race.

FEMS Microbiol Rev 2014 Jan 22;38(1):41-55. Epub 2013 Jul 22.

Unit of Molecular Parasitology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1111/1574-6976.12032DOI Listing
January 2014

(Post-) Genomic approaches to tackle drug resistance in Leishmania.

Parasitology 2013 Oct 12;140(12):1492-505. Epub 2013 Mar 12.

Molecular Parasitology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.

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http://dx.doi.org/10.1017/S0031182013000140DOI Listing
October 2013

LC-MS metabolomics from study design to data-analysis - using a versatile pathogen as a test case.

Comput Struct Biotechnol J 2013 6;4:e201301002. Epub 2013 Feb 6.

Unit of Molecular Parasitology, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium ; Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

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http://dx.doi.org/10.5936/csbj.201301002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962178PMC
June 2014

Drug-resistant microorganisms with a higher fitness--can medicines boost pathogens?

Crit Rev Microbiol 2013 Nov 6;39(4):384-94. Epub 2012 Sep 6.

Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp , Antwerpen , Belgium.

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http://dx.doi.org/10.3109/1040841X.2012.716818DOI Listing
November 2013

Antimonial resistance in Leishmania donovani is associated with increased in vivo parasite burden.

PLoS One 2011 1;6(8):e23120. Epub 2011 Aug 1.

Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023120PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148249PMC
December 2011

Detection of Leptomonas sp. parasites in clinical isolates of Kala-azar patients from India.

Infect Genet Evol 2010 Oct 13;10(7):1145-50. Epub 2010 Jul 13.

Infectious Disease Research Laboratory, Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, UP, India.

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http://dx.doi.org/10.1016/j.meegid.2010.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933273PMC
October 2010