Manolis Pasparakis

Cell Mol Gastroenterol Hepatol 2019 Oct 10. Epub 2019 Oct 10.

Rheumatology; Department of Medicine, Autonomous University of Barcelona, Plaça Cívica, 08193 Bellaterra, Barcelona, Spain. Electronic address:

Cell Death Dis 2019 Sep 18;10(10):692. Epub 2019 Sep 18.

Center for Inflammation Research, VIB, Ghent, Belgium.

Immunity 2019 Aug 23;51(2):367-380.e4. Epub 2019 Jul 23.

Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany. Electronic address:

Nat Cell Biol 2019 06 13;21(6):731-742. Epub 2019 May 13.

Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Center for Molecular Medicine, University of Cologne, Cologne, Germany.

Cell Death Differ 2019 Apr 15. Epub 2019 Apr 15.

Institute for Genetics, University of Cologne, D-50674, Cologne, Germany.

Mol Cell 2019 02 28;73(3):413-428.e7. Epub 2018 Dec 28.

The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Mary-Jean Mitchell Green Building, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK. Electronic address:

Nat Commun 2019 02 8;10(1):688. Epub 2019 Feb 8.

Department I of Internal Medicine, University of Cologne, 50937, Cologne, Germany.

Trends Mol Med 2019 01 16;25(1):47-63. Epub 2018 Nov 16.

Institute for Genetics, University of Cologne, D-50674 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, D-50931 Cologne, Germany; Center for Molecular Medicine (CMMC), University of Cologne, D-50931, Cologne, Germany. Electronic address:

Cell Rep 2019 01;26(3):536-545.e4

Biomedical Sciences Research Centre (BSRC) "Alexander Fleming," Vari 16672, Greece; Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece. Electronic address:

J Exp Med 2018 11 25;215(11):2868-2886. Epub 2018 Sep 25.

Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany

Cell Rep 2018 10;25(4):1027-1039.e6

Department I of Internal Medicine, University Hospital Cologne, Weyertal 115b, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), University of Cologne, Joseph Stelzmann Straße 26, 50931 Cologne, Germany; Center for Molecular Medicine, University Hospital Cologne, Robert Koch Straße 21, 50931 Cologne. Electronic address:

Sci Signal 2018 09 4;11(546). Epub 2018 Sep 4.

Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA.

Nat Commun 2018 09 25;9(1):3910. Epub 2018 Sep 25.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK.

Science 2018 08;361(6404):756-757

Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

PLoS One 2018 9;13(3):e0194048. Epub 2018 Mar 9.

Institute for Genetics, University of Cologne, Cologne, Germany.

Cancer Res 2018 06 27;78(11):2939-2951. Epub 2018 Mar 27.

Laboratory for Molecular Respiratory Carcinogenesis, Department of Physiology, Faculty of Medicine, University of Patras, Rio, Greece.

J Clin Invest 2018 05 16;128(5):2064-2075. Epub 2018 Apr 16.

Department of Molecular, Cell and Cancer Biology, and.

J Immunol 2018 04 12;200(8):3020-3021. Epub 2018 Mar 12.

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

Nat Commun 2018 02 12;9(1):618. Epub 2018 Feb 12.

Biomedical Sciences Research Center "Alexander Fleming", 16672, Vari, Greece.

J Immunol 2018 01 6;200(2):737-748. Epub 2017 Dec 6.

Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605;

J Pathol 2017 11 21;243(3):320-330. Epub 2017 Sep 21.

Louvain Centre for Toxicology and Applied Pharmacology (LTAP), Institut de Recherche Experimentale et Clinique (IREC), Université catholique de Louvain, Brussels, Belgium.

Curr Top Microbiol Immunol 2017;403:77-93

Institute for Genetics, University of Cologne, 50674, Cologne, Germany.

J Immunol 2017 06 1;198(11):4435-4447. Epub 2017 May 1.

Medical Scientist Training Program, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111;

Mol Cell 2017 Jun 11;66(5):698-710.e5. Epub 2017 May 11.

Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Mary-Jean Mitchell Green Building, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK. Electronic address:

J Clin Invest 2017 Jun 19;127(7):2662-2677. Epub 2017 Jun 19.

Institute for Genetics.

Immunol Rev 2017 05;277(1):113-127

Institute for Genetics, University of Cologne, Cologne, Germany.

Nature 2016 12 7;540(7631):124-128. Epub 2016 Nov 7.

Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.

Hepatology 2016 08 18;64(2):508-21. Epub 2016 Apr 18.

I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Nature 2016 08 3;536(7615):215-8. Epub 2016 Aug 3.

Science 2016 Aug;353(6299):603-8

Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA. Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 QiuYue Road, PuDong District, Shanghai, 201210, China.

Nat Commun 2016 08 26;7:12508. Epub 2016 Aug 26.

Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Centre for Molecular Medicine (CMMC), University of Cologne, Joseph-Stelzmann-Straβe 26, Cologne 50931, Germany.

Immunity 2016 07 5;45(1):46-59. Epub 2016 Jul 5.

Program in Pharmacology and Experimental Therapeutics, Sackler Graduate School, Tufts University, Boston, MA 02111, USA.

Gut 2016 06 11;65(6):935-43. Epub 2015 Mar 11.

Institute for Genetics, University of Cologne, Cologne, Germany Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany Department of Medical Protein Research, VIB, Ghent, Belgium Department of Biochemistry, Ghent University, Ghent, Belgium.

Blood 2016 06 5;127(22):2732-41. Epub 2016 Apr 5.

Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Center of Integrated Oncology, University Hospital of Cologne, Cologne, Germany; and Center of Molecular Medicine, University of Cologne, Cologne, Germany.

EMBO Mol Med 2016 06 1;8(6):609-25. Epub 2016 Jun 1.

Hubertus Wald Cancer Center, Department of Oncology and Hematology University Medical Center Hamburg-Eppendorf, Hamburg, Germany Department of Hematology and Oncology, Augsburg Medical Center, Augsburg, Germany

J Biol Chem 2016 Mar 19;291(11):5765-73. Epub 2016 Jan 19.

the Dipartimento di Scienze e Tecnologie, Università del Sannio, Via Port'Arsa 11, 82100 Benevento, Italy, the Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli, 80131 Napoli, Italy.

Clin Immunol 2016 Mar 23;164:52-6. Epub 2016 Jan 23.

Center of Chronic Immunodeficiency, University Medical Center Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Germany. Electronic address:

Immunity 2016 Mar;44(3):553-567

Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; Center for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany. Electronic address:

J Hepatol 2016 Jan 5;64(1):94-102. Epub 2015 Sep 5.

Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland. Electronic address:

J Exp Med 2015 Dec 30;212(13):2235-51. Epub 2015 Nov 30.

Biomedical Sciences Research Center "Alexander Fleming", 16672 Vari, Greece Department of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece

Cancer Cell 2015 Dec 14;28(6):830. Epub 2015 Dec 14.

Cancer Cell 2015 11;28(5):582-598

Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; Center for Molecular Medicine (CMMC), University of Cologne, 50931, Cologne, Germany. Electronic address:

J Exp Med 2015 Sep 7;212(10):1529-49. Epub 2015 Sep 7.

Institute of Experimental and Clinical Pharmacology and Toxicology and Department of Radiation Oncology, University of Lübeck, 23562 Lübeck, Germany German Research Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany

J Exp Med 2015 Sep;212(10):1483

Institute for Genetics and CECAD Research Center, University of Cologne

J Exp Med 2015 Apr 30;212(4):525-38. Epub 2015 Mar 30.

Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany The German Cancer Consortium (DKTK), 69120 Heidelberg, Germany

Nature 2015 Jan;517(7534):311-20

1] VIB Inflammation Research Center, Ghent University, UGhent-VIB Research Building FSVM, 9052 Ghent, Belgium [2] Department of Biomedical Molecular Biology, Ghent University, 9000 Ghent, Belgium. [3] Methusalem program, Ghent University, Technologiepark 927, B-9052 Ghent, Belgium.

Elife 2014 Dec 2;3. Epub 2014 Dec 2.

Institute of Molecular Biotechnology, Vienna, Austria.

Cancer Cell 2014 Dec;26(6):880-895

Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), 69121 Heidelberg, Germany; Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany; German Cancer Consortium, 69120 Heidelberg, Germany. Electronic address:

PLoS One 2014 28;9(1):e87530. Epub 2014 Jan 28.

Departments of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, Kentucky, United States of America ; James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky, United States of America.

Proc Natl Acad Sci U S A 2014 Nov 10;111(47):16836-41. Epub 2014 Nov 10.

Clinic for Nephrology and Hypertension, Christian-Albrechts-University Kiel, 24105 Kiel, Germany;

Proc Natl Acad Sci U S A 2014 Oct 22;111(40):14436-41. Epub 2014 Sep 22.

Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605;

J Biol Chem 2014 Sep 2;289(36):25227-40. Epub 2014 Jul 2.

From the Lineberger Comprehensive Cancer Center University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599,

Nature 2014 Sep 17;513(7516):90-4. Epub 2014 Aug 17.

1] Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany [2].

Cell Rep 2014 Sep 21;8(5):1308-17. Epub 2014 Aug 21.

Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Drive, Oxford OX37FY, UK. Electronic address:

J Exp Med 2014 Sep 1;211(10):2103-18. Epub 2014 Sep 1.

Herbert Irving Comprehensive Cancer Center, Department of Pathology and Cell Biology, and Department of Microbiology and Immunology, Columbia University, New York, NY 10032 Herbert Irving Comprehensive Cancer Center, Department of Pathology and Cell Biology, and Department of Microbiology and Immunology, Columbia University, New York, NY 10032 Herbert Irving Comprehensive Cancer Center, Department of Pathology and Cell Biology, and Department of Microbiology and Immunology, Columbia University, New York, NY 10032

J Neurosci 2014 Sep;34(39):12982-99

Department of Neurology, German Institute for Dementia Prevention (DIDP), and.

J Immunol 2014 Aug 11;193(4):1539-1543. Epub 2014 Jul 11.

Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Nat Commun 2014 Aug 19;5:4585. Epub 2014 Aug 19.

1] Institut Curie/INSERM U759, Campus Universitaire, Bat 112, 91405 Orsay Cedex, France [2] CNRS, Centre de Génétique Moléculaire, UPR3404, Avenue de la Terrasse, F-91198 Gif-sur-Yvette, France.

EMBO Mol Med 2014 Jul;6(7):970-83

Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany

Nat Rev Immunol 2014 May 11;14(5):289-301. Epub 2014 Apr 11.

St John's Institute of Dermatology and Guy's and St Thomas' Hospital National Institute for Health Research Biomedical Research Centre, King's College London, SE1 9RT London, UK.

J Exp Med 2014 May 21;211(5):769-79. Epub 2014 Apr 21.

Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), D-69120 Heidelberg, Germany.

J Immunol 2013 Nov 27;191(9):4720-30. Epub 2013 Sep 27.

Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642;

Immunity 2013 Nov 7;39(5):899-911. Epub 2013 Nov 7.

Department of Dermatology, University of Cologne, Kerpener Strasse 62, 50931 Cologne, Germany; Institute for Genetics, Center for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.

PLoS One 2013 13;8(2):e55620. Epub 2013 Feb 13.

Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, Germany.

Mol Cell 2013 Aug 1;51(3):283-96. Epub 2013 Aug 1.

Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

PLoS One 2013 22;8(1):e54128. Epub 2013 Jan 22.

Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.

Am J Physiol Renal Physiol 2012 Nov 12;303(10):F1473-85. Epub 2012 Sep 12.

Univ. of Cologne, Dept. II of Internal Medicine, Cologne, Germany.

Circulation 2012 Oct 30;126(14):1739-51. Epub 2012 Aug 30.

Institute for Genetics, University of Cologne, Zülpicher Strasse 47a, D-50674 Cologne, Germany.

Cell Rep 2012 Sep 30;2(3):478-87. Epub 2012 Aug 30.

Institutes of Molecular Medicine and Experimental Immunology, Universität Bonn, 53105 Bonn, Germany.

PLoS Pathog 2012 1;8(3):e1002570. Epub 2012 Mar 1.

Unit of Molecular Signal Transduction in Inflammation, Department for Molecular Biomedical Research, VIB, Ghent, Belgium [corrected].

Blood 2012 Jul 10;120(3):613-25. Epub 2012 May 10.

Department of Dermatology, University of Cologne, Kerpenerstrasse 62, Cologne, Germany.

Cancer Cell 2012 Jul;22(1):91-105

Institute of Neuropathology, University Hospital Zurich, CH-8091 Zurich, Switzerland.

PLoS One 2011 17;6(11):e27435. Epub 2011 Nov 17.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

Nat Immunol 2012 May;13(5):481-90

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Cell Host Microbe 2012 Mar;11(3):223-5

Institute for Genetics, University of Cologne, Cologne, Germany.

Immunol Rev 2012 Mar;246(1):346-58

Institute for Genetics, University of Cologne, Cologne, Germany.

PLoS One 2011 14;6(10):e25942. Epub 2011 Oct 14.

Institute for Genetics, Centre for Molecular Medicine (CMMC), Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

J Biol Chem 2011 Dec 4;286(52):44776-87. Epub 2011 Nov 4.

Institut für Physiologie II, Westfälische Wilhelms-Universität Münster, 48149 Münster, Germany.

PLoS One 2011 9;6(6):e21055. Epub 2011 Jun 9.

Centre for Molecular Medicine, Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany.

Immunity 2011 Oct 13;35(4):572-82. Epub 2011 Oct 13.

Institute for Genetics, Center for Molecular Medicine, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.

Nat Genet 2011 Aug 14;43(9):908-12. Epub 2011 Aug 14.

Department for Molecular Biomedical Research, Unit of Molecular Signal Transduction in Inflammation, Vlaams Instituut voor Biotechnologie, Ghent, Belgium.

J Clin Invest 2011 Jul 23;121(7):2781-93. Epub 2011 Jun 23.

Institute for Genetics, Center for Molecular Medicine, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany.

Nature 2011 Jul 31;477(7364):330-4. Epub 2011 Jul 31.

Institute for Genetics, Centre for Molecular Medicine, University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.

Brain 2011 Apr 10;134(Pt 4):1184-98. Epub 2011 Feb 10.

Department of Neuropathology, University of Freiburg, Breisacher Str. 64, D-79106 Freiburg, Germany.

Nature 2011 Mar;471(7340):637-41

Frankfurt Institute for Molecular Life Sciences and Institute of Biochemistry II, Goethe University School of Medicine, Theodor-Stern-Kai 7, D-60590 Frankfurt, Main, Germany.

Cell Res 2011 Jan 14;21(1):146-58. Epub 2010 Dec 14.

Institute for Genetics, Centre for Molecular Medicine, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Zülpicher Strasse 47a, 50674 Cologne, Germany.

J Immunol 2010 Dec 10;185(12):7646-53. Epub 2010 Nov 10.

Unit of Molecular Signal Transduction in Inflammation, Department for Molecular Biomedical Research, Flanders Institute for Biotechnology (VIB), Ghent, Belgium.

Nature 2010 Nov 29;468(7320):98-102. Epub 2010 Sep 29.

IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, 1030 Vienna, Austria.

J Exp Med 2010 Jul 7;207(7):1513-23. Epub 2010 Jun 7.

Department for Molecular Biomedical Research, VIB, B-9052 Ghent, Belgium.

Curr Dir Autoimmun 2010 18;11:80-93. Epub 2010 Feb 18.

Centre for Molecular Medicine and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Institute of Genetics, University of Cologne, Zülpicher Strasse 47, Cologne, Germany.

J Biol 2009 ;8(10):93

Division of Immunoregulation, MRC National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK.

Mol Cell 2010 Feb;37(3):418-28

Department of Experimental Oncology, European Institute of Oncology, IFOM-IEO Campus, 20139 Milan, Italy.

Nat Rev Immunol 2009 Nov;9(11):778-88

Institute of Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Zülpicher Strasse 47, 50674 Cologne, Germany.

J Neurosci 2009 Oct;29(41):12919-29

pharmazentrum frankfurt, Zentrum für Arzneimittelforschung, Entwicklung und Sicherheit, Department of Clinical Pharmacology, Goethe University, 60590 Frankfurt, Germany.

PLoS One 2009 Sep 29;4(9):e7163. Epub 2009 Sep 29.

Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

Nat Immunol 2009 Jun 3;10(6):647-54. Epub 2009 May 3.

Immune Disease Institute, Boston, Massachusetts, USA.

Genesis 2009 May;47(5):323-9

Institute for Genetics, Centre for Molecular Medicine, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Germany.

Cell Metab 2008 Nov;8(5):372-83

Institute of Genetics, Centre for Molecular Medicine (CMMC), Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Zülpicher Str. 47, 50674 Cologne, Germany.

Proc Natl Acad Sci U S A 2008 Aug 19;105(34):12435-8. Epub 2008 Aug 19.

Immune Disease Institute, Harvard Medical School, Boston, MA 02115, USA.