Manisha H Shah

Manisha H Shah

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Manisha H Shah

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Nivolumab in metastatic adrenocortical carcinoma: results of a phase II trial.

J Clin Endocrinol Metab 2019 Jul 5. Epub 2019 Jul 5.

Developmental Therapeutics Program, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL.

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http://dx.doi.org/10.1210/jc.2019-00600DOI Listing
July 2019

The emerging role of targeted therapies for advanced well-differentiated gastroenteropancreatic neuroendocrine tumors.

Expert Rev Clin Pharmacol 2019 Feb 16;12(2):101-108. Epub 2019 Jan 16.

d Department of Surgery The Urban Meyer III and Shelley Meyer Chair for Cancer Research Professor of Surgery, Oncology, and Health Services Management and Policy , The Ohio State University, Wexner Medical Center , Columbus , OH , USA.

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http://dx.doi.org/10.1080/17512433.2019.1561273DOI Listing
February 2019

Pioglitazone Therapy of PAX8-PPARγ Fusion Protein Thyroid Carcinoma.

J Clin Endocrinol Metab 2018 04;103(4):1277-1281

Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1210/jc.2017-02533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456920PMC
April 2018

Favorable and Durable Response to Pazopanib in Metastatic Refractory Paraganglioma.

J Oncol Pract 2017 12 29;13(12):840-842. Epub 2017 Aug 29.

The Ohio State University Comprehensive Cancer Center and The Ohio State University Wexner Medical Center, Columbus, OH.

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http://dx.doi.org/10.1200/JOP.2017.024984DOI Listing
December 2017

Endocrine dysfunction following immune checkpoint inhibitor therapy.

Curr Opin Endocrinol Diabetes Obes 2017 Oct;24(5):337-347

aDivision of Medical Oncology, Department of Internal Medicine bDivision of Endocrinology, Diabetes, and Metabolism, The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio, USA.

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http://dx.doi.org/10.1097/MED.0000000000000357DOI Listing
October 2017

Cabozantinib As Salvage Therapy for Patients With Tyrosine Kinase Inhibitor-Refractory Differentiated Thyroid Cancer: Results of a Multicenter Phase II International Thyroid Oncology Group Trial.

J Clin Oncol 2017 Oct 17;35(29):3315-3321. Epub 2017 Aug 17.

Maria E. Cabanillas and Komal Shah, The University of Texas MD Anderson Cancer Center, Houston, TX; Jonas A. de Souza, University of Chicago Medical Center, Chicago, IL; Susan Geyer, University of South Florida, Tampa; Michael E. Menefee, Mayo Clinic Jacksonville, Jacksonville, FL; Lori J. Wirth, Massachusetts General Hospital, Boston, MA; Stephen V. Liu, MedStar Georgetown University Hospital; John Wright, National Cancer Institute, Washington, DC; and Manisha H. Shah, Ohio State University, Columbus, OH.

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http://ascopubs.org/doi/10.1200/JCO.2017.73.0226
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http://dx.doi.org/10.1200/JCO.2017.73.0226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652872PMC
October 2017

Transforming Growth Factor β1-Induced NADPH Oxidase-4 Expression and Fibrotic Response in Conjunctival Fibroblasts.

Invest Ophthalmol Vis Sci 2017 06;58(7):3011-3017

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Victoria, Australia 2Ophthalmology, University of Melbourne, Department of Surgery, Melbourne, Australia.

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http://dx.doi.org/10.1167/iovs.16-20633DOI Listing
June 2017

Incidence and timing of common adverse events in Lenvatinib-treated patients from the SELECT trial and their association with survival outcomes.

Endocrine 2017 Apr 3;56(1):121-128. Epub 2017 Feb 3.

Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s12020-017-1233-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368192PMC
April 2017

Transarterial Chemoembolization for Metastatic Neuroendocrine Tumors With Massive Hepatic Tumor Burden: Is the Benefit Worth the Risk?

Ann Surg Oncol 2016 11 8;23(12):4008-4015. Epub 2016 Jul 8.

Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1245/s10434-016-5333-xDOI Listing
November 2016

Phase I study of IMGN901, a CD56-targeting antibody-drug conjugate, in patients with CD56-positive solid tumors.

Invest New Drugs 2016 06 9;34(3):290-9. Epub 2016 Mar 9.

Academic Unit of Clinical Oncology, Weston Park Hospital, University of Sheffield, Whitham Road, Sheffield, S10 2SJ, UK.

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http://dx.doi.org/10.1007/s10637-016-0336-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859861PMC
June 2016

Radiation Recall Dermatitis With Concomitant Dabrafenib and Pazopanib Therapy.

JAMA Dermatol 2016 05;152(5):587-9

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus.

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http://dx.doi.org/10.1001/jamadermatol.2015.5366DOI Listing
May 2016

Evaluation of patients with disseminated or locoregionally advanced thyroid cancer: a primer for medical oncologists.

Am Soc Clin Oncol Educ Book 2012 :384-8

From the Stanford Cancer Institute, Stanford University, Palo Alto, CA; The Ohio State University Comprehensive Cancer Center, Columbus, OH.

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http://dx.doi.org/10.14694/EdBook_AM.2012.32.384DOI Listing
April 2016

Elevated Alkaline Phosphatase Prior to Transarterial Chemoembolization for Neuroendocrine Tumors Predicts Worse Outcomes.

J Gastrointest Surg 2016 Mar 21;20(3):580-6. Epub 2015 Oct 21.

Division of Surgical Oncology, The Ohio State University Wexner Medical Center, 250 Cherry St, Grand Rapids, MI, 49503, USA.

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http://dx.doi.org/10.1007/s11605-015-2998-6DOI Listing
March 2016

The Raf Kinase Inhibitor Sorafenib Inhibits JAK-STAT Signal Transduction in Human Immune Cells.

J Immunol 2015 Sep 3;195(5):1995-2005. Epub 2015 Aug 3.

Department of Surgery, The Ohio State University, Columbus, OH 43210; Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210; Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH 43210

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http://www.jimmunol.org/content/early/2015/08/01/jimmunol.14
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1400084
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http://dx.doi.org/10.4049/jimmunol.1400084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546911PMC
September 2015

Differential effects of superoxide dismutase and superoxide dismutase/catalase mimetics on human breast cancer cells.

Breast Cancer Res Treat 2015 Apr 21;150(3):523-34. Epub 2015 Mar 21.

Victorian Breast Cancer Research, Invasion and Metastasis Unit, St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, VIC, 3065, Australia,

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http://link.springer.com/10.1007/s10549-015-3329-z
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http://dx.doi.org/10.1007/s10549-015-3329-zDOI Listing
April 2015

Bone metastases in well-to-moderately differentiated neuroendocrine tumors: a single institutional review from the Ohio State University Medical Center.

Pancreas 2015 Mar;44(2):198-203

From the *Department of Internal Medicine, †Center for Biostatistics, ‡College of Medicine, and §Comprehensive Cancer Center, Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1097/MPA.0000000000000267DOI Listing
March 2015

Smad-independent pathway involved in transforming growth factor β1-induced Nox4 expression and proliferation of endothelial cells.

Naunyn Schmiedebergs Arch Pharmacol 2015 Mar 27;388(3):319-26. Epub 2014 Nov 27.

Centre for Eye Research Australia, University of Melbourne, Level 1, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.

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http://dx.doi.org/10.1007/s00210-014-1070-5DOI Listing
March 2015

Bone metastases and skeletal-related events from neuroendocrine tumors.

Endocr Connect 2015 Mar 27;4(1):9-17. Epub 2014 Nov 27.

The UCSF Helen Diller Family Comprehensive Cancer CenterUniversity of California, San Francisco, 1600 Divisadero Street, UCSF Box 1770, San Francisco, California 94143, USAThe Ohio State University Comprehensive Cancer CenterColumbus, Ohio 43210, USANational Comprehensive Cancer NetworkFort Washington, Pennsylvania 19034, USA.

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http://dx.doi.org/10.1530/EC-14-0119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285767PMC
March 2015

Impact of prior chemotherapy use on the efficacy of everolimus in patients with advanced pancreatic neuroendocrine tumors: a subgroup analysis of the phase III RADIANT-3 trial.

Pancreas 2015 Mar;44(2):181-9

From the *Department of Medical Oncology, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France; †Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; ‡Department of Oncology, Mayo Clinic College of Medicine, Rochester, MN; §Digestive Oncology, University Hospitals Gasthuisberg/Leuven, Leuven, Belgium; ∥Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA; ¶Department of Oncology Biometrics and Data, and #Department of Oncology, Novartis Pharmaceuticals Corporation, East Hanover, NJ; **Department of Medical Oncology, The Ohio State University, Columbus, OH; ††Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona, Spain; and ‡‡Division of Surgical Oncology, Oregon Health & Science University, Portland, OR.

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http://dx.doi.org/10.1097/MPA.0000000000000262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327560PMC
March 2015

New era for treatment in differentiated thyroid cancer.

Lancet 2014 Jul 24;384(9940):286-8. Epub 2014 Apr 24.

Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(14)60663-2DOI Listing
July 2014

An update on clinical trials of targeted therapies in thyroid cancer.

Curr Opin Oncol 2014 Jan;26(1):36-44

The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.

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http://dx.doi.org/10.1097/CCO.0000000000000029DOI Listing
January 2014

Cabozantinib in progressive medullary thyroid cancer.

J Clin Oncol 2013 Oct 3;31(29):3639-46. Epub 2013 Sep 3.

Rossella Elisei, University of Pisa, Pisa; Lisa Licitra, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico-Istituto Nazionale dei Tumori, Milan, Italy; Martin J. Schlumberger, Institut Gustave Roussy, University Paris-Sud, Villejuif, France; Stefan P. Müller, Universitatsklinikum Essen, Essen; Michael C. Kreissl, Universitätsklinikum Würzburg, Würzburg, Germany; Patrick Schöffski, University Hospitals Leuven, Leuven, Belgium; Marcia S. Brose, University of Pennsylvania Abramson Cancer Center, Philadelphia, PA; Manisha H. Shah, Ohio State University Medical Center, Columbus, OH; Barbara Jarzab, Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach, Gliwice, Poland; Viktor Medvedev, Medical Radiological Research Centre of the Russian Academy of Medical Sciences, Obninsk, Russia; Bruno Niederle, Medizinische Universität Wien, Wien, Austria; Ezra E.W. Cohen, University of Chicago, Chicago, IL; Lori J. Wirth, Massachusetts General Hospital, Boston, MA; Haythem Ali, Henry Ford Health System, Detroit, MI; Colin Hessel and Yifah Yaron, Exelixis, South San Francisco, CA; Douglas Ball and Barry Nelkin, Johns Hopkins University School of Medicine, Baltimore, MD; and Steven I. Sherman, University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2012.48.4659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164813PMC
October 2013

Liver-directed therapies in patients with advanced neuroendocrine tumors.

J Natl Compr Canc Netw 2012 Jun;10(6):765-74

Department of Surgery, The Ohio State University, Columbus, OH, USA.

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June 2012

Radiation pneumonitis following yttrium-90 radioembolization: case report and literature review.

J Vasc Interv Radiol 2012 May;23(5):669-74

Department of Radiology, Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1016/j.jvir.2012.01.059DOI Listing
May 2012

Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.

Endocr Relat Cancer 2012 Feb 9;19(1):29-38. Epub 2012 Jan 9.

Division of Endocrinology, Diabetes and Metabolism, The Ohio State University and The Arthur G. James Cancer Hospital, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1530/ERC-11-0155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717592PMC
February 2012

Role of BRAF in thyroid oncogenesis.

Clin Cancer Res 2011 Dec 7;17(24):7511-7. Epub 2011 Sep 7.

Ohio State University College of Medicine, Divisions of Surgical Oncology and Medical Oncology, James Cancer Center & Solove Research Institute, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1155DOI Listing
December 2011

Thyroid cancer: pathogenesis and targeted therapy.

Ther Adv Endocrinol Metab 2011 Oct;2(5):173-95

Division of Medical Oncology, Department of Internal Medicine, Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1177/2042018811419889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474640PMC
October 2011

Targeting RET receptor tyrosine kinase activation in cancer.

Clin Cancer Res 2010 Dec 7;16(24):5936-41. Epub 2010 Oct 7.

Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0786DOI Listing
December 2010

Thyroid cancer: emerging role for targeted therapies.

Ther Adv Med Oncol 2010 Jan;2(1):3-16

Division of Endocrinology, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1177/1758834009352667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126004PMC
January 2010

New therapeutic advances in the management of progressive thyroid cancer.

Endocr Relat Cancer 2009 Sep 13;16(3):715-31. Epub 2009 Feb 13.

Department of Internal Medicine, The Ohio State University, A438 Starling-Loving Hall, 320 West 10th Avenue, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1677/ERC-08-0335DOI Listing
September 2009

Phase II trial of sorafenib in metastatic thyroid cancer.

J Clin Oncol 2009 Apr 2;27(10):1675-84. Epub 2009 Mar 2.

Ohio State University, Department of Internal Medicine, Molecular Virology, Immunology, and Genetics, Pathology, Radiology, Center for Biostatistics, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1200/JCO.2008.18.2717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668972PMC
April 2009

G3139 (Genasense) in patients with advanced merkel cell carcinoma.

Am J Clin Oncol 2009 Apr;32(2):174-9

Division of Hematology and Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1097/COC.0b013e31817eebf8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311264PMC
April 2009

The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid.

World J Surg Oncol 2008 Nov 25;6:125. Epub 2008 Nov 25.

Department of Surgery, Ohio State University Medical Center, Columbus, Ohio, USA.

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http://wjso.biomedcentral.com/articles/10.1186/1477-7819-6-1
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http://dx.doi.org/10.1186/1477-7819-6-125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605455PMC
November 2008

Phase II study of thalidomide in patients with metastatic carcinoid and islet cell tumors.

Cancer Chemother Pharmacol 2008 Apr 23;61(4):661-8. Epub 2007 Jun 23.

Division of Hematology-Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, A438 Starling-Loving Hall, 320 West 10th Avenue, Columbus, OH 43210, USA.

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http://link.springer.com/10.1007/s00280-007-0521-9
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http://dx.doi.org/10.1007/s00280-007-0521-9DOI Listing
April 2008

Tissue and serum alpha 2-3- and alpha 2-6-linkage specific sialylation changes in oral carcinogenesis.

Glycoconj J 2008 Apr 25;25(3):279-90. Epub 2007 Dec 25.

Biochemistry Research Division, The Gujarat Cancer & Research Institute, NCH Campus, Asarwa, Ahmedabad 380 016, India.

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http://dx.doi.org/10.1007/s10719-007-9086-4DOI Listing
April 2008

Repeat transarterial chemoembolization (TACE) for progressive hepatic carcinoid metastases provides results similar to first TACE.

J Gastrointest Surg 2007 Dec 25;11(12):1680-5. Epub 2007 Sep 25.

Division of Surgical Oncology, Department of Surgery, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.

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http://dx.doi.org/10.1007/s11605-007-0235-7DOI Listing
December 2007

Gastrointestinal stromal tumors involving the prostate: presentation, course, and therapeutic approach.

Urology 2007 Jun;69(6):1209.e5-7

Department of Internal Medicine, Division of Hematology/Oncology, Ohio State University, Columbus, Ohio 43210-1280, USA.

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http://dx.doi.org/10.1016/j.urology.2007.03.029DOI Listing
June 2007

Type-2 dominant cytokine gene expression following hepatic surgery.

J Hepatobiliary Pancreat Surg 2006 ;13(5):442-9

Division of Surgical Oncology, University of California Davis Medical Center, 4501, X Street, Suite #3010, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1007/s00534-006-1103-7DOI Listing
March 2007

Hepatic artery chemoembolization in 122 patients with metastatic carcinoid tumor: lessons learned.

J Gastrointest Surg 2007 Mar;11(3):264-71

Department of Surgery, James Cancer Hospital and Solove Research Institute, Ohio State University Medical Center, Columbus, OH, 43210, USA.

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http://link.springer.com/10.1007/s11605-007-0089-z
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http://dx.doi.org/10.1007/s11605-007-0089-zDOI Listing
March 2007

A phase I study of ultra low dose interleukin-2 and stem cell factor in patients with HIV infection or HIV and cancer.

Clin Cancer Res 2006 Jul;12(13):3993-6

Division of Hematology/Oncology, Department of Internal Medicine, Ohio State University, Columbus, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0268DOI Listing
July 2006

Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors.

Clin Cancer Res 2006 Jul;12(13):3997-4003

Division of Hematology-Oncology, Department of Internal Medicine, Ohio State University, Columbus 43210, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-2689DOI Listing
July 2006

Phase II study of celecoxib in metastatic differentiated thyroid carcinoma.

J Clin Endocrinol Metab 2006 Jun 7;91(6):2201-4. Epub 2006 Mar 7.

Division of Hematology, Departments of Internal Medicine, The Ohio State University Thyroid Cancer Unit, The Ohio State University Medical Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1210/jc.2005-2498DOI Listing
June 2006

STAT-1-mediated repression of monocyte interleukin-10 gene expression in vivo.

Eur J Immunol 2006 Mar;36(3):623-30

Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1002/eji.200535241DOI Listing
March 2006

Neuroendocrine tumors.

J Natl Compr Canc Netw 2006 Feb;4(2):102-38

Comprehensive Cancer Center, University of California-San Francisco, San Francisco, CA, USA.

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February 2006

A review of proteomics in cancer research.

Asian Pac J Cancer Prev 2005 Apr-Jun;6(2):113-7

Biochemistry Research Division, The Gujarat Cancer and Research Institute, Ahmedabad 380016, India.

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September 2005

AIDS-associated malignancies.

Cancer Chemother Biol Response Modif 2003 ;21:717-46

The Ohio State University, Columbus 43210, USA.

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September 2004

Phase II study of the proteasome inhibitor bortezomib (PS-341) in patients with metastatic neuroendocrine tumors.

Clin Cancer Res 2004 Sep;10(18 Pt 1):6111-8

Division of Hematology-Oncology, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0422DOI Listing
September 2004

AIDS-associated malignancies.

Cancer Chemother Biol Response Modif 2002 ;20:633-64

Divisions of Hematology-Oncology and Human Cancer Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, A 438 Starling Loving Hall, 320 West 10th Avenue, Columbus, OH 43210, USA.

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May 2003

A Study of Various Sociodemographic Factors and Plasma Vitamin Levels in Oral and Pharyngeal Cancer in Gujarat, India.

Asian Pac J Cancer Prev 2001 Jul-Sep;2(3):215-224

Biochemistry Research Division, The Gujarat Cancer & Research Institute, Ahmedabad - 380 016, INDIA.

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April 2003