Publications by authors named "Manish R Sharma"

36Publications

The Resurgence of Antibody Drug Conjugates in Cancer Therapeutics: Novel Targets and Payloads.

Am Soc Clin Oncol Educ Book 2020 Mar;40:1-17

START (South Texas Accelerated Research Therapeutics), San Antonio, TX.

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http://dx.doi.org/10.1200/EDBK_281107DOI Listing
March 2020

Prolonged Pharmacokinetic Interaction Between Capecitabine and a CYP2C9 Substrate, Celecoxib.

J Clin Pharmacol 2019 12 5;59(12):1632-1640. Epub 2019 Jul 5.

Department of Medicine, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1002/jcph.1476DOI Listing
December 2019

A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2018 08 9;82(2):309-317. Epub 2018 Jun 9.

Section of Hematology Oncology, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, MC 2115, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1007/s00280-018-3619-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739841PMC
August 2018

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

J Clin Oncol 2018 06 13;36(16):1611-1618. Epub 2018 Feb 13.

Jason J. Luke, Jeffrey M. Lemons, Theodore G. Karrison, Sean P. Pitroda, James M. Melotek, Yuanyuan Zha, Hania A. Al-Hallaq, Ainhoa Arina, Nikolai N. Khodarev, Linda Janisch, Paul Chang, Jyoti D. Patel, Gini F. Fleming, John Moroney, Manish R. Sharma, Mark J. Ratain, Thomas F. Gajewski, Ralph R. Weichselbaum, and Steven J. Chmura, The University of Chicago, Chicago, IL; Julia R. White, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2017.76.2229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978468PMC
June 2018

Strategies to manage chemotherapy-induced peripheral neuropathy.

Authors:
Manish R Sharma

Clin Adv Hematol Oncol 2017 Dec;15(12):938-940

University of Chicago, Chicago, Illinois.

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December 2017

PharmGKB summary: pazopanib pathway, pharmacokinetics.

Pharmacogenet Genomics 2017 08;27(8):307-312

Departments of aBiomedical Data Sciences bBiomedical Engineering cGenetics, Stanford University, Stanford, California dDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862561PMC
August 2017

Taking a Measured Approach to Toxicity Data in Phase I Oncology Clinical Trials.

Clin Cancer Res 2016 Feb 14;22(3):527-9. Epub 2015 Oct 14.

Department of Medicine and Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738103PMC
February 2016

Resampling the N9741 trial to compare tumor dynamic versus conventional end points in randomized phase II trials.

J Clin Oncol 2015 Jan 27;33(1):36-41. Epub 2014 Oct 27.

Manish R. Sharma, Elizabeth Gray, and Theodore G. Karrison, University of Chicago, Chicago, IL; Richard M. Goldberg, Ohio State University, Columbus, OH; and Daniel J. Sargent, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2014.57.2826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268251PMC
January 2015

Early and Severe Radiation Esophagitis Associated With Concurrent Sirolimus.

J Clin Oncol 2016 Mar 14;34(9):e73-5. Epub 2014 Jul 14.

Pritzker School of Medicine, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2013.50.1643DOI Listing
March 2016

Severe irinotecan-induced toxicity in a patient with UGT1A1 28 and UGT1A1 6 polymorphisms.

World J Gastroenterol 2013 Jun;19(24):3899-903

Affiliated Hospital Cancer Center, Academy of Military Medical Science, Beijing 100071, China.

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http://dx.doi.org/10.3748/wjg.v19.i24.3899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699040PMC
June 2013

Why RECIST works and why it should stay--reply to counterpoint.

Cancer Res 2012 Oct 4;72(20):5158. Epub 2012 Sep 4.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1988DOI Listing
October 2012

RECIST: no longer the sharpest tool in the oncology clinical trials toolbox---point.

Cancer Res 2012 Oct 4;72(20):5145-9; discussion 5150. Epub 2012 Sep 4.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0058DOI Listing
October 2012

Resampling phase III data to assess phase II trial designs and endpoints.

Clin Cancer Res 2012 Apr 27;18(8):2309-15. Epub 2012 Jan 27.

Departments of Medicine and Health Studies, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328614PMC
April 2012

Role of randomized phase III trials in an era of effective targeted therapies.

Nat Rev Clin Oncol 2011 Dec 6;9(4):208-14. Epub 2011 Dec 6.

Section of Hematology/Oncology, Department of Medicine, and Comprehensive Cancer Center, University of Chicago, 5841 South Maryland Avenue, MC 2115, Chicago, IL 60637-1470, USA.

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http://dx.doi.org/10.1038/nrclinonc.2011.190DOI Listing
December 2011

Randomized phase II trials: a long-term investment with promising returns.

J Natl Cancer Inst 2011 Jul 27;103(14):1093-100. Epub 2011 Jun 27.

Department of Medicine, University of Chicago, Chicago, IL 60637-1470, USA.

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http://dx.doi.org/10.1093/jnci/djr218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139588PMC
July 2011

GI cancers in 2010: New standards and a predictive biomarker for adjuvant therapy.

Nat Rev Clin Oncol 2011 Feb;8(2):70-2

Section of Hematology-Oncology, Department of Medicine, Comprehensive Cancer Center, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637-1470, USA.

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http://dx.doi.org/10.1038/nrclinonc.2010.219DOI Listing
February 2011

Other paradigms: better treatments are identified by better trials: the value of randomized phase II studies.

Cancer J 2009 Sep-Oct;15(5):426-30

Section of Hematology, University of Chicago Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1097/PPO.0b013e3181b9c5d5DOI Listing
April 2010

Airway obstruction caused by PTEN hamartoma (Bannayan-Riley-Ruvalcaba) syndrome.

Arch Otolaryngol Head Neck Surg 2007 Nov;133(11):1157-60

Department of Internal Medicine, Division of Medical Genetics and Molecular Medicine, University of Michigan Health System, 1500 E Medical Center Drive, Ann Arbor, MI 48109-0241, USA.

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http://dx.doi.org/10.1001/archotol.133.11.1157DOI Listing
November 2007