Publications by authors named "Manfred Wuhrer"

100Publications

Dissecting Total Plasma and Protein-Specific Glycosylation Profiles in Congenital Disorders of Glycosylation.

Int J Mol Sci 2020 Oct 15;21(20). Epub 2020 Oct 15.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.3390/ijms21207635DOI Listing
October 2020

Intact and subunit-specific analysis of bispecific antibodies by sheathless CE-MS.

Anal Chim Acta 2020 Oct 21;1134:18-27. Epub 2020 Aug 21.

Leiden University Medical Center, Center for Proteomics and Metabolomics, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2020.07.069DOI Listing
October 2020

MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc -Glycosylation.

Front Immunol 2020 21;11:2049. Epub 2020 Aug 21.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2020.02049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472933PMC
August 2020

Immunoglobulin G Glycoprofiles are Unaffected by Common Bottom-Up Sample Processing.

J Proteome Res 2020 Oct 18;19(10):4158-4162. Epub 2020 Sep 18.

Center of Proteomics and Metabolomics, Leiden University Medical Center, P.O. Box 9600, Postzone, P1-Q, Leiden 2300 RC, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.0c00656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539295PMC
October 2020

Sheathless CE-MS as a tool for monitoring exchange efficiency and stability of bispecific antibodies.

Electrophoresis 2020 Sep 9. Epub 2020 Sep 9.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/elps.202000166DOI Listing
September 2020

Site-Specific Glycosylation Mapping of Fc Gamma Receptor IIIb from Neutrophils of Individual Healthy Donors.

Anal Chem 2020 Oct 22;92(19):13172-13181. Epub 2020 Sep 22.

Center for Proteomics and Metabolomics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.0c02342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547861PMC
October 2020

Improved N- and C-Terminal Sequencing of Proteins by Combining Positive and Negative Ion MALDI In-Source Decay Mass Spectrometry.

Anal Chem 2020 Sep 1;92(18):12429-12436. Epub 2020 Sep 1.

Center for Proteomics & Metabolomics, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.0c02198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498143PMC
September 2020

Author Correction: Human DC-SIGN and CD23 do not interact with human IgG.

Sci Rep 2020 Jul 23;10(1):12560. Epub 2020 Jul 23.

Department Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-020-68760-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378241PMC
July 2020

Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer.

Protein Cell 2020 Jun 25. Epub 2020 Jun 25.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s13238-020-00741-7DOI Listing
June 2020

Differential - and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior.

Front Oncol 2020 2;10:732. Epub 2020 Jun 2.

Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fonc.2020.00732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280451PMC
June 2020

Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin.

Anal Chem 2020 07 9;92(14):9476-9481. Epub 2020 Jul 9.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.0c01794DOI Listing
July 2020

IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants.

J Allergy Clin Immunol 2020 Sep 21;146(3):652-666.e11. Epub 2020 May 21.

Laboratories of Immunology and Antibody Glycan Analysis, Institute for Nutritional Medicine, University of Lübeck and University Medical Center Schleswig-Holstein, Lübeck, Germany; Laboratory of Tolerance and Autoimmunity at the German Rheumatism Research Center, a Leibniz Institute, Berlin, Germany; Airway Research Center North, University of Lübeck, German Center for Lung Research, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.04.059DOI Listing
September 2020

FcγR Binding and ADCC Activity of Human IgG Allotypes.

Front Immunol 2020 6;11:740. Epub 2020 May 6.

Sanquin Research and Landsteiner Laboratory, Department of Experimental Immunohematology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2020.00740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218058PMC
May 2020

Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype.

Cell Mol Life Sci 2020 Mar 31. Epub 2020 Mar 31.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Postbus 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00018-020-03504-zDOI Listing
March 2020

IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia.

Sci Rep 2020 02 20;10(1):3051. Epub 2020 Feb 20.

Sanquin Research, Department of Experimental Immunohematology, Amsterdam, The Netherlands and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-020-59651-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033207PMC
February 2020

Characterization of Macrophage Galactose-type Lectin (MGL) ligands in colorectal cancer cell lines.

Biochim Biophys Acta Gen Subj 2020 04 3;1864(4):129513. Epub 2020 Jan 3.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2020.129513DOI Listing
April 2020

Functional Attributes of Antibodies, Effector Cells, and Target Cells Affecting NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity.

J Immunol 2019 12 20;203(12):3126-3135. Epub 2019 Nov 20.

Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands;

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http://dx.doi.org/10.4049/jimmunol.1900985DOI Listing
December 2019

IgG Fc glycosylation as an axis of humoral immunity in childhood.

J Allergy Clin Immunol 2020 02 24;145(2):710-713.e9. Epub 2019 Oct 24.

Division of Immunology, Boston Children's Hospital, Boston, Mass; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010538PMC
February 2020

Expanding the Reaction Space of Linkage-Specific Sialic Acid Derivatization.

Molecules 2019 Oct 8;24(19). Epub 2019 Oct 8.

Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.

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http://dx.doi.org/10.3390/molecules24193617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803949PMC
October 2019

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.

Authors:
Maria Lorna A De Leoz David L Duewer Adam Fung Lily Liu Hoi Kei Yau Oscar Potter Gregory O Staples Kenichiro Furuki Ruth Frenkel Yunli Hu Zoran Sosic Peiqing Zhang Friedrich Altmann Clemens Gru Nwald-Grube Chun Shao Joseph Zaia Waltraud Evers Stuart Pengelley Detlev Suckau Anja Wiechmann Anja Resemann Wolfgang Jabs Alain Beck John W Froehlich Chuncui Huang Yan Li Yaming Liu Shiwei Sun Yaojun Wang Youngsuk Seo Hyun Joo An Niels-Christian Reichardt Juan Echevarria Ruiz Stephanie Archer-Hartmann Parastoo Azadi Len Bell Zsuzsanna Lakos Yanming An John F Cipollo Maja Pucic-Bakovic Jerko Štambuk Gordan Lauc Xu Li Peng George Wang Andreas Bock René Hennig Erdmann Rapp Marybeth Creskey Terry D Cyr Miyako Nakano Taiki Sugiyama Pui-King Amy Leung Paweł Link-Lenczowski Jolanta Jaworek Shuang Yang Hui Zhang Tim Kelly Song Klapoetke Rui Cao Jin Young Kim Hyun Kyoung Lee Ju Yeon Lee Jong Shin Yoo Sa-Rang Kim Soo-Kyung Suh Noortje de Haan David Falck Guinevere S M Lageveen-Kammeijer Manfred Wuhrer Robert J Emery Radoslaw P Kozak Li Phing Liew Louise Royle Paulina A Urbanowicz Nicolle H Packer Xiaomin Song Arun Everest-Dass Erika Lattová Samanta Cajic Kathirvel Alagesan Daniel Kolarich Toyin Kasali Viv Lindo Yuetian Chen Kudrat Goswami Brian Gau Ravi Amunugama Richard Jones Corné J M Stroop Koichi Kato Hirokazu Yagi Sachiko Kondo C T Yuen Akira Harazono Xiaofeng Shi Paula E Magnelli Brian T Kasper Lara Mahal David J Harvey Roisin O'Flaherty Pauline M Rudd Radka Saldova Elizabeth S Hecht David C Muddiman Jichao Kang Prachi Bhoskar Daniele Menard Andrew Saati Christine Merle Steven Mast Sam Tep Jennie Truong Takashi Nishikaze Sadanori Sekiya Aaron Shafer Sohei Funaoka Masaaki Toyoda Peter de Vreugd Cassie Caron Pralima Pradhan Niclas Chiang Tan Yehia Mechref Sachin Patil Jeffrey S Rohrer Ranjan Chakrabarti Disha Dadke Mohammedazam Lahori Chunxia Zou Christopher Cairo Béla Reiz Randy M Whittal Carlito B Lebrilla Lauren Wu Andras Guttman Marton Szigeti Benjamin G Kremkow Kelvin H Lee Carina Sihlbom Barbara Adamczyk Chunsheng Jin Niclas G Karlsson Jessica Örnros Göran Larson Jonas Nilsson Bernd Meyer Alena Wiegandt Emy Komatsu Helene Perreault Edward D Bodnar Nassur Said Yannis-Nicolas Francois Emmanuelle Leize-Wagner Sandra Maier Anne Zeck Albert J R Heck Yang Yang Rob Haselberg Ying Qing Yu William Alley Joseph W Leone Hua Yuan Stephen E Stein

Mol Cell Proteomics 2020 01 7;19(1):11-30. Epub 2019 Oct 7.

Mass Spectrometry Data Center, Biomolecular Measurement Division, Material Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Drive Gaithersburg, Maryland 20899.

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http://dx.doi.org/10.1074/mcp.RA119.001677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944243PMC
January 2020

Paucity of Paucimannosylation Revoked.

Authors:
Manfred Wuhrer

Proteomics 2019 11;19(21-22):e1900244

Center for Proteomics and Metabolomics, Leiden University Medical Center, Postbus 9600, 2300RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pmic.201900244DOI Listing
November 2019

N-glycome signatures in human plasma: associations with physiology and major diseases.

FEBS Lett 2019 11 9;593(21):2966-2976. Epub 2019 Oct 9.

Center for Proteomics and Metabolomics, Leiden University Medical Center, the Netherlands.

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http://dx.doi.org/10.1002/1873-3468.13598DOI Listing
November 2019

Dried blood spot N-glycome analysis by MALDI mass spectrometry.

Talanta 2019 Dec 29;205:120104. Epub 2019 Jun 29.

Center for Proteomics and Metabolomics, Leiden University Medical Center, 2300, RC, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.talanta.2019.06.104DOI Listing
December 2019

Site-specific N- and O-glycosylation analysis of atacicept.

MAbs 2019 Aug/Sep;11(6):1053-1063. Epub 2019 Jul 26.

a Division of BioAnalytical Chemistry, VU University Amsterdam , Amsterdam , The Netherlands.

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http://dx.doi.org/10.1080/19420862.2019.1630218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748583PMC
January 2020

Human DC-SIGN and CD23 do not interact with human IgG.

Sci Rep 2019 07 10;9(1):9995. Epub 2019 Jul 10.

Department Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-46484-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620288PMC
July 2019

Monitoring of immunoglobulin N- and O-glycosylation in health and disease.

Glycobiology 2020 03;30(4):226-240

Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1093/glycob/cwz048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225405PMC
March 2020

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples.

Nat Commun 2019 05 13;10(1):2137. Epub 2019 May 13.

Leiden University Medical Center, Center for Proteomics and Metabolomics, Postbus 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09910-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513864PMC
May 2019

N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines.

Cells 2019 03 22;8(3). Epub 2019 Mar 22.

Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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https://www.mdpi.com/2073-4409/8/3/273
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http://dx.doi.org/10.3390/cells8030273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468459PMC
March 2019

Serum protein N-glycosylation changes in multiple myeloma.

Biochim Biophys Acta Gen Subj 2019 05 5;1863(5):960-970. Epub 2019 Mar 5.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2019.03.001DOI Listing
May 2019

The Role of Glycosphingolipids in Immune Cell Functions.

Front Immunol 2019 29;10:90. Epub 2019 Jan 29.

Department of Immunopathology, Sanquin Research, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361815PMC
December 2019

Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells.

J Proteome Res 2019 03 9;18(3):1125-1132. Epub 2019 Jan 9.

Center for Proteomics and Metabolomics , Leiden University Medical Center , 2300 RC Leiden , The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.8b00796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399673PMC
March 2019

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry.

Anal Chem 2019 02 8;91(3):2079-2085. Epub 2019 Jan 8.

Center for Proteomics and Metabolomics , Leiden University Medical Center (LUMC) , PO Box 9600, 2300 RC , Leiden , The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b04515
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http://dx.doi.org/10.1021/acs.analchem.8b04515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365908PMC
February 2019

α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin-Sialyl LewisX Interaction.

Thromb Haemost 2018 Dec 19;118(12):2134-2144. Epub 2018 Nov 19.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675601
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http://dx.doi.org/10.1055/s-0038-1675601DOI Listing
December 2018

Comparative Glycomics of Immunoglobulin A and G From Saliva and Plasma Reveals Biomarker Potential.

Front Immunol 2018 23;9:2436. Epub 2018 Oct 23.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02436
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http://dx.doi.org/10.3389/fimmu.2018.02436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206042PMC
September 2019

Unique patterns of glycosylation in immunoglobulin subclass G4-related disease and primary sclerosing cholangitis.

J Gastroenterol Hepatol 2019 Oct 22;34(10):1878-1886. Epub 2018 Nov 22.

Sanquin Research, Department of Immunopathology, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1111/jgh.14512
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http://dx.doi.org/10.1111/jgh.14512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899843PMC
October 2019

Plasma protein N-glycan signatures of type 2 diabetes.

Biochim Biophys Acta Gen Subj 2018 12 6;1862(12):2613-2622. Epub 2018 Aug 6.

Department of Internal Medicine, ErasmusMC, University Medical Center, Rotterdam, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03044165183024
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http://dx.doi.org/10.1016/j.bbagen.2018.08.005DOI Listing
December 2018

Automated Plasma Glycomics with Linkage-Specific Sialic Acid Esterification and Ultrahigh Resolution MS.

Anal Chem 2018 10 3;90(20):11955-11961. Epub 2018 Oct 3.

Center for Proteomics and Metabolomics , Leiden University Medical Center , 2300 RC Leiden , The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.8b02391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209171PMC
October 2018

Serum -glycome alterations in colorectal cancer associate with survival.

Oncotarget 2018 Jul 17;9(55):30610-30623. Epub 2018 Jul 17.

Center for Proteomics and Metabolomics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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http://www.oncotarget.com/fulltext/25753
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http://dx.doi.org/10.18632/oncotarget.25753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078140PMC
July 2018

Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG.

Nat Commun 2018 07 25;9(1):2916. Epub 2018 Jul 25.

Center for Proteomics and Metabolomics, Leiden University Medical Centre, Zone S3, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41467-018-05173-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060135PMC
July 2018

Biophysical analysis of sialic acid recognition by the complement regulator Factor H.

Glycobiology 2018 10;28(10):765-773

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1093/glycob/cwy061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142864PMC
October 2018

Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies.

Ann Rheum Dis 2018 10 26;77(10):1471-1479. Epub 2018 Jun 26.

Sanquin Research and Landsteiner Laboratory, Department of Immunopathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2018-213299DOI Listing
October 2018

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis.

mBio 2018 06 19;9(3). Epub 2018 Jun 19.

Division of Pediatric Infectious Diseases & Immunology, Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/mBio.00546-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016251PMC
June 2018

Immunoglobulin G Fragment Crystallizable Glycosylation After Hematopoietic Stem Cell Transplantation Is Dissimilar to Donor Profiles.

Front Immunol 2018 4;9:1238. Epub 2018 Jun 4.

Department of Pediatrics, Section Immunology, Hematology and Stem Cell Transplantation, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.01238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994695PMC
August 2019

Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG.

J Neuroimmunol 2018 07 16;320:19-24. Epub 2018 Apr 16.

Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2018.04.010DOI Listing
July 2018

Serum sialylation changes in cancer.

Glycoconj J 2018 04 21;35(2):139-160. Epub 2018 Apr 21.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Postzone S3, Postbus 9600, 2300 RC, Leiden, NL, The Netherlands.

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http://link.springer.com/10.1007/s10719-018-9820-0
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http://dx.doi.org/10.1007/s10719-018-9820-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916985PMC
April 2018

ACPA IgG galactosylation associates with disease activity in pregnant patients with rheumatoid arthritis.

Ann Rheum Dis 2018 08 3;77(8):1130-1136. Epub 2018 Apr 3.

Department of Rheumatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2018-212946DOI Listing
August 2018

An In-Depth Glycosylation Assay for Urinary Prostate-Specific Antigen.

Anal Chem 2018 04 14;90(7):4414-4421. Epub 2018 Mar 14.

Leiden University Medical Center , Center for Proteomics and Metabolomics , 2300 RC Leiden , The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.7b04281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885261PMC
April 2018

The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans.

Glycoconj J 2018 04 3;35(2):217-231. Epub 2018 Mar 3.

Department of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Jagiellonian University, Kraków, Poland.

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http://dx.doi.org/10.1007/s10719-018-9814-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916991PMC
April 2018

Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice.

Mol Immunol 2018 02 19;94:54-60. Epub 2017 Dec 19.

Department Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.12.006DOI Listing
February 2018

N- and -glycosylation Analysis of Human C1-inhibitor Reveals Extensive Mucin-type -Glycosylation.

Mol Cell Proteomics 2018 06 12;17(6):1225-1238. Epub 2017 Dec 12.

From the ‡Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1074/mcp.RA117.000240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986245PMC
June 2018

Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation.

Sci Rep 2017 11 30;7(1):16623. Epub 2017 Nov 30.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-16811-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709460PMC
November 2017

IgG glycosylation and DNA methylation are interconnected with smoking.

Biochim Biophys Acta Gen Subj 2018 Mar 18;1862(3):637-648. Epub 2017 Oct 18.

Research Unit Molecular Epidemiology, Institute of Epidemiology 2, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology 2, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.10.012DOI Listing
March 2018

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation.

Sci Rep 2017 08 15;7(1):8187. Epub 2017 Aug 15.

Department of Experimental Immunohematology, Sanquin Research, Amsterdam, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-08654-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557851PMC
August 2017