Manfred Nairz

Manfred Nairz

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Manfred Nairz

Manfred Nairz

Publications by authors named "Manfred Nairz"

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Dopamine Is a Siderophore-Like Iron Chelator That Promotes Serovar Typhimurium Virulence in Mice.

MBio 2019 02 5;10(1). Epub 2019 Feb 5.

Department of Internal Medicine II (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria

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http://dx.doi.org/10.1128/mBio.02624-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428752PMC
February 2019

Infections Associated with Iron Administration.

Met Ions Life Sci 2019 Jan;19

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http://dx.doi.org/10.1515/9783110527872-011DOI Listing
January 2019

Iron in the Tumor Microenvironment-Connecting the Dots.

Front Oncol 2018 26;8:549. Epub 2018 Nov 26.

Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Innsbruck, Austria.

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https://www.frontiersin.org/article/10.3389/fonc.2018.00549/
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http://dx.doi.org/10.3389/fonc.2018.00549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275298PMC
November 2018

Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases.

Int J Mol Sci 2018 Oct 23;19(11). Epub 2018 Oct 23.

Department of Internal Medicine II, Medical University Innsbruck, Innsbruck 6020, Austria.

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http://www.mdpi.com/1422-0067/19/11/3285
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http://dx.doi.org/10.3390/ijms19113285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274989PMC
October 2018

Iron and innate antimicrobial immunity-Depriving the pathogen, defending the host.

J Trace Elem Med Biol 2018 Jul 10;48:118-133. Epub 2018 Mar 10.

Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.jtemb.2018.03.007DOI Listing
July 2018

Dopamine promotes cellular iron accumulation and oxidative stress responses in macrophages.

Biochem Pharmacol 2018 02 5;148:193-201. Epub 2017 Dec 5.

Department of Internal Medicine II (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, A-6020 Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.12.001DOI Listing
February 2018

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis.

Sci Rep 2017 10 12;7(1):13012. Epub 2017 Oct 12.

Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1038/s41598-017-13046-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638901PMC
October 2017

Genetic and Dietary Iron Overload Differentially Affect the Course of Typhimurium Infection.

Front Cell Infect Microbiol 2017 11;7:110. Epub 2017 Apr 11.

Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of InnsbruckInnsbruck, Austria.

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http://dx.doi.org/10.3389/fcimb.2017.00110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387078PMC
September 2017

"Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels.

Pflugers Arch 2017 04 1;469(3-4):397-418. Epub 2017 Mar 1.

Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00424-017-1944-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362662PMC
April 2017

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.

Blood 2017 01 18;129(4):405-414. Epub 2016 Nov 18.

Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, and.

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http://dx.doi.org/10.1182/blood-2016-06-721571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270389PMC
January 2017

Heme oxygenase 1 controls early innate immune response of macrophages to Salmonella Typhimurium infection.

Cell Microbiol 2016 10 18;18(10):1374-89. Epub 2016 Mar 18.

Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1111/cmi.12578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557132PMC
October 2016

Iron deficiency or anemia of inflammation? : Differential diagnosis and mechanisms of anemia of inflammation.

Wien Med Wochenschr 2016 Oct 24;166(13-14):411-423. Epub 2016 Aug 24.

Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s10354-016-0505-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065583PMC
October 2016

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.

Cell Rep 2015 Dec 25;13(10):2048-55. Epub 2015 Nov 25.

Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, 93053 Regensburg, Germany. Electronic address:

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http://www.cell.com/cms/attachment/2041386719/2055161577/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S221112471501292
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http://dx.doi.org/10.1016/j.celrep.2015.11.005DOI Listing
December 2015

Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.

Circ Heart Fail 2015 Sep 31;8(5):980-7. Epub 2015 Jul 31.

From the Center for Systems Biology, Massachusetts General Hospital, Boston (S.H., B.G.C., A.F., A.A., M.N., I.H., Y.S., Y.-X.Y., Y.I., B.T., R.W., M.N., F.K.S.); Biological Sciences, GlaxoSmithKline, Collegeville, PA (M.B.); Department of Systems Biology, Harvard Medical School, Boston, MA (R.W.); GlaxoSmithKline, King of Prussia, PA (C.M.); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA (P.L.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568849PMC
September 2015

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria.

Metallomics 2015 Jun;7(6):1036-45

Department of Internal Medicine VI, Medical University of Innsbruck, Anichstraße 35, A - 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1039/c4mt00328dDOI Listing
June 2015

'Ride on the ferrous wheel'--the cycle of iron in macrophages in health and disease.

Immunobiology 2015 Feb 16;220(2):280-94. Epub 2014 Sep 16.

Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2014.09.010DOI Listing
February 2015

Iron at the interface of immunity and infection.

Front Pharmacol 2014 16;5:152. Epub 2014 Jul 16.

Department of Internal Medicine VI-Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck Innsbruck, Austria.

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http://dx.doi.org/10.3389/fphar.2014.00152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100575PMC
July 2014

Lipocalin-2 ameliorates granulocyte functionality.

Eur J Immunol 2012 Dec 7;42(12):3346-57. Epub 2012 Nov 7.

Department of Internal Medicine, Clinical Immunology and Infectious Diseases, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1002/eji.201142351DOI Listing
December 2012

Slc11a1 (Nramp1) impairs growth of Salmonella enterica serovar typhimurium in macrophages via stimulation of lipocalin-2 expression.

J Leukoc Biol 2012 Aug 15;92(2):353-9. Epub 2012 Jun 15.

Department of Internal Medicine I, Clinical Immunology and Infectious Diseases, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1189/jlb.1111554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395419PMC
August 2012

The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection.

J Cell Sci 2012 Jun 16;125(Pt 11):2698-708. Epub 2012 Mar 16.

Biocenter, Division of Cell Biology, Innsbruck Medical University, Innsbruck 6020, Austria.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.100073
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http://dx.doi.org/10.1242/jcs.100073DOI Listing
June 2012

The pleiotropic effects of erythropoietin in infection and inflammation.

Microbes Infect 2012 Mar 4;14(3):238-46. Epub 2011 Nov 4.

Department of Internal Medicine I, Clinical Immunology and Infectious Diseases, Innsbruck Medical University, Anichstr. 35, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.micinf.2011.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278592PMC
March 2012

Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo.

Haematologica 2011 Dec 22;96(12):1761-9. Epub 2011 Aug 22.

Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.3324/haematol.2011.048926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232257PMC
December 2011

The struggle for iron - a metal at the host-pathogen interface.

Cell Microbiol 2010 Dec 21;12(12):1691-702. Epub 2010 Oct 21.

Department of Internal Medicine I, Clinical Immunology and Infectious Diseases, Medical University of Innsbruck, Austria.

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http://doi.wiley.com/10.1111/j.1462-5822.2010.01529.x
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http://dx.doi.org/10.1111/j.1462-5822.2010.01529.xDOI Listing
December 2010

Slc11a1 limits intracellular growth of Salmonella enterica sv. Typhimurium by promoting macrophage immune effector functions and impairing bacterial iron acquisition.

Cell Microbiol 2009 Sep 2;11(9):1365-81. Epub 2009 Jun 2.

Department of Internal Medicine I, Clinical Immunology and Infectious Diseases, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1462-5822.2009.01337.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467104PMC
September 2009

Nramp1-functionality increases iNOS expression via repression of IL-10 formation.

Eur J Immunol 2008 Nov;38(11):3060-7

Department of Internal Medicine, Innsbruck Medical University, Austria.

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http://dx.doi.org/10.1002/eji.200838449DOI Listing
November 2008

Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.

Eur J Immunol 2008 Jul;38(7):1923-36

Department of General Internal Medicine, Clinical Immunology and Infectious Diseases, Medical University Innsbruck, Anichstrasse 35, Innsbruck, Austria.

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http://dx.doi.org/10.1002/eji.200738056DOI Listing
July 2008

Modulation of macrophage iron transport by Nramp1 (Slc11a1).

Immunobiology 2007 14;212(9-10):751-7. Epub 2007 Nov 14.

Department of General Internal Medicine, Clinical Immunology and Infectious Diseases, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.imbio.2007.09.014DOI Listing
March 2008

Autocrine formation of hepcidin induces iron retention in human monocytes.

Blood 2008 Feb 11;111(4):2392-9. Epub 2007 Dec 11.

Department of General Internal Medicine, Medical University, Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1182/blood-2007-05-090019DOI Listing
February 2008

The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimurium.

Cell Microbiol 2007 Sep 25;9(9):2126-40. Epub 2007 Apr 25.

Department of General Internal Medicine, Clinical Immunology and Infectious Diseases, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1462-5822.2007.00942.xDOI Listing
September 2007

Molecular and clinical aspects of iron homeostasis: From anemia to hemochromatosis.

Wien Klin Wochenschr 2006 Aug;118(15-16):442-62

Klinische Abteilung für Allgemeine Innere Medizin, Klinische Infektiologie und Immunologie, Medizinische Universität Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00508-006-0653-7DOI Listing
August 2006