Manfred Fliegauf

Manfred Fliegauf

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Manfred Fliegauf

Manfred Fliegauf

Publications by authors named "Manfred Fliegauf"

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Assessing the Functional Relevance of Variants in the () in a Cohort of Patients With Primary Immunodeficiency.

Front Immunol 2019 16;10:568. Epub 2019 Apr 16.

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.00568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477086PMC
April 2019

Nuclear factor κB mutations in human subjects: The devil is in the details.

J Allergy Clin Immunol 2018 Oct 28;142(4):1062-1065. Epub 2018 Aug 28.

Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183119
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http://dx.doi.org/10.1016/j.jaci.2018.06.050DOI Listing
October 2018

NFKB1 regulates human NK cell maturation and effector functions.

Clin Immunol 2017 02 3;175:99-108. Epub 2016 Dec 3.

Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili di Brescia, Italy.

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http://dx.doi.org/10.1016/j.clim.2016.11.012DOI Listing
February 2017

Disturbed canonical nuclear factor of κ light chain signaling in B cells of patients with common variable immunodeficiency.

J Allergy Clin Immunol 2017 01 14;139(1):220-231.e8. Epub 2016 Jun 14.

Center for Chronic Immunodeficiency, University Medical Center and University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.04.043DOI Listing
January 2017

Early and late B-cell developmental impairment in nuclear factor kappa B, subunit 1-mutated common variable immunodeficiency disease.

J Allergy Clin Immunol 2017 01 16;139(1):349-352.e1. Epub 2016 Jul 16.

Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Italy.

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http://dx.doi.org/10.1016/j.jaci.2016.05.045DOI Listing
January 2017

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

Cell 2016 11 27;167(5):1264-1280.e18. Epub 2016 Oct 27.

Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.09.054DOI Listing
November 2016

The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia.

Biochem Biophys Res Commun 2016 05 10;473(4):1177-1184. Epub 2016 Apr 10.

Division of Nephrology and Immunology, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2016.04.036DOI Listing
May 2016

Haploinsufficiency of the NF-κB1 Subunit p50 in Common Variable Immunodeficiency.

Am J Hum Genet 2015 Sep 13;97(3):389-403. Epub 2015 Aug 13.

Center for Chronic Immunodeficiency, University Medical Center Freiburg and University of Freiburg, Freiburg 79108, Germany; Institute of Immunity and Transplantation, University College London, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564940PMC
September 2015

Hyper-IgE syndromes: reviewing PGM3 deficiency.

Curr Opin Pediatr 2014 Dec;26(6):697-703

Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.

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http://pdfs.journals.lww.com/co-pediatrics/2014/12000/Hyper_
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http://dx.doi.org/10.1097/MOP.0000000000000158DOI Listing
December 2014

Mucociliary clearance defects in a murine in vitro model of pneumococcal airway infection.

PLoS One 2013 19;8(3):e59925. Epub 2013 Mar 19.

Centre of Chronic Immunodeficiency, University Medical Centre Freiburg and University of Freiburg, Freiburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059925PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602288PMC
September 2013

RPGR mutations might cause reduced orientation of respiratory cilia.

Pediatr Pulmonol 2013 Apr 6;48(4):352-63. Epub 2012 Aug 6.

Department of Molecular and Clinical Genetics, Institute of Human Genetics Polish Academy of Sciences, Poznań, Poland.

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http://dx.doi.org/10.1002/ppul.22632DOI Listing
April 2013

HDAC6 as a target for antileukemic drugs in acute myeloid leukemia.

Leuk Res 2012 Aug 29;36(8):1055-62. Epub 2012 Mar 29.

Department of Hematology/Oncology, University of Freiburg Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.02.026DOI Listing
August 2012

U1 snRNA-mediated gene therapeutic correction of splice defects caused by an exceptionally mild BBS mutation.

Hum Mutat 2011 Jul;32(7):815-24

University of Zurich, Institute of Medical Molecular Genetics, Schorenstrasse 16, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1002/humu.21509DOI Listing
July 2011

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

Haematologica 2008 Nov 11;93(11):1728-33. Epub 2008 Sep 11.

Department of Medicine, Division Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, D-79106 Freiburg, Germany.

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http://dx.doi.org/10.3324/haematol.13044DOI Listing
November 2008

When cilia go bad: cilia defects and ciliopathies.

Nat Rev Mol Cell Biol 2007 Nov;8(11):880-93

Department of Paediatrics and Adolescent Medicine, University Hospital Freiburg, 79106 Freiburg, Germany.

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http://m.mf.uni-lj.si/dokumenti/798914094ab057c9780d4fad722c
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http://search.proquest.com/openview/19ad37937984c72e3afc6366
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http://www.nature.com/doifinder/10.1038/nrm2278
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http://dx.doi.org/10.1038/nrm2278DOI Listing
November 2007

Nephrocystin and ciliary defects not only in the kidney?

Pediatr Nephrol 2007 Jun 20;22(6):765-9. Epub 2007 Feb 20.

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http://dx.doi.org/10.1007/s00467-007-0434-1DOI Listing
June 2007

Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines.

Leuk Res 2007 Apr 20;31(4):497-506. Epub 2006 Oct 20.

Department of Medicine, Division of Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, D-79106 Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2006.08.008DOI Listing
April 2007

Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression.

J Leukoc Biol 2006 Dec 25;80(6):1462-72. Epub 2006 Sep 25.

Division Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, Freiburg D-79106, Germany.

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http://doi.wiley.com/10.1189/jlb.0106005
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http://dx.doi.org/10.1189/jlb.0106005DOI Listing
December 2006

Novel tools to unravel molecular mechanisms in cilia-related disorders.

Trends Genet 2006 May 24;22(5):241-5. Epub 2006 Mar 24.

Department of Pediatrics and Adolescent Medicine, University Hospital Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1016/j.tig.2006.03.002DOI Listing
May 2006

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.

Am J Respir Cell Mol Biol 2005 Jul 21;33(1):41-7. Epub 2005 Apr 21.

Department of Pediatrics and Adolescent Medicine, Albert-Ludwigs-University, Freiburg, Germany.

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http://dx.doi.org/10.1165/rcmb.2004-0335OCDOI Listing
July 2005

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

Am J Respir Crit Care Med 2005 Jun 4;171(12):1343-9. Epub 2005 Mar 4.

Department of Pediatrics and Adolescent Medicine, Mathildenstrasse 1, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1164/rccm.200411-1583OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718478PMC
June 2005

Williams-Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO.

Oncogene 2004 Dec;23(56):9070-81

Division of Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, D-79106 Freiburg, Germany.

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http://www.nature.com/articles/1208042
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http://dx.doi.org/10.1038/sj.onc.1208042DOI Listing
December 2004

Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation.

Hum Mol Genet 2004 Sep 21;13(18):2133-41. Epub 2004 Jul 21.

Laboratory of Molecular Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddh219DOI Listing
September 2004

Identification of novel genes of the bone-specific transcription factor Runx2.

J Bone Miner Res 2004 Jun;19(6):959-72

Division of Hematology/Oncology, University of Freiburg Medical Center, Germany.

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http://doi.wiley.com/10.1359/jbmr.2004.19.6.959
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http://dx.doi.org/10.1359/jbmr.2004.19.6.959DOI Listing
June 2004

Identification of the human CYS1 gene and candidate gene analysis in Boichis disease.

Pediatr Nephrol 2003 Jun 6;18(6):498-505. Epub 2003 May 6.

Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1007/s00467-003-1141-1DOI Listing
June 2003

Genomic characterization of the RUNX2 gene of Fugu rubripes.

Gene 2002 May;291(1-2):159-67

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetterstrasse 55, D-79106 Freiburg, Germany.

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May 2002