Publications by authors named "Manfred Dietel"

100Publications

[Quality assurance in diagnostic in situ hybridization-experience of QuIP].

Pathologe 2020 Nov;41(6):614-620

Qualitätssicherungs-Initiative Pathologie QuIP GmbH, Berlin, Deutschland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00292-020-00832-6DOI Listing
November 2020

Next generation sequencing of lung adenocarcinoma subtypes with intestinal differentiation reveals distinct molecular signatures associated with histomorphology and therapeutic options.

Lung Cancer 2019 12 11;138:43-51. Epub 2019 Oct 11.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Pathology, Berlin, Germany; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2019.10.005DOI Listing
December 2019

RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance.

BMC Cancer 2018 Nov 22;18(1):1158. Epub 2018 Nov 22.

Charité-Universitätsmedizin Berlin corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, 10117, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-5070-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251223PMC
November 2018

Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.

Int J Cancer 2019 02 7;144(3):569-581. Epub 2018 Nov 7.

Charité Universitätsmedizin Berlin, Institute of Pathology, Laboratory of Molecular Tumor Pathology and Systems Biology, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.31892DOI Listing
February 2019

Treatment decisions, clinical outcomes, and pharmacoeconomics in the treatment of patients with EGFR mutated stage III/IV NSCLC in Germany: an observational study.

BMC Cancer 2018 Feb 5;18(1):135. Epub 2018 Feb 5.

Internistische Onkologie der Thoraxtumoren, Thoraxklinik im Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-4032-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799904PMC
February 2018

Programmed Death-Ligand 1 Immunohistochemistry Testing: A Review of Analytical Assays and Clinical Implementation in Non-Small-Cell Lung Cancer.

J Clin Oncol 2017 Dec 20;35(34):3867-3876. Epub 2017 Oct 20.

Reinhard Büttner, University Hospital Cologne, Cologne; Manfred Dietel, Charité Universitätsmedizin Berlin, Berlin, Germany; John R. Gosney, Royal Liverpool University Hospital, Liverpool; Andrew C. Wotherspoon, Royal Marsden Hospital, London; Keith M. Kerr, Aberdeen University Medical School and Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom; Birgit Guldhammer Skov, Copenhagen University Hospital, Copenhagen, Denmark; Julien Adam, Gustave Roussy Cancer Center, Villejuif; Frédérique Penault-Llorca, Jean Perrin Comprehensive Cancer Center, Clermont-Ferrand, France; Noriko Motoi, National Cancer Center Hospital, Tokyo, Japan; Kenneth J. Bloom, Human Longevity, San Diego, CA; John W. Longshore, Carolinas Pathology Group, Charlotte, NC; Fernando López-Ríos, Hospital Universitario HM Sanchinarro, Madrid, Spain; Giuseppe Viale, University of Milan, Milan, Italy; and Ming-Sound Tsao, University Health Network, Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.74.7642DOI Listing
December 2017

Influence of mucinous and necrotic tissue in colorectal cancer samples on KRAS mutation analysis.

Pathol Res Pract 2017 Jun 6;213(6):606-611. Epub 2017 May 6.

Institute of Pathology, Charité, University Medicine Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prp.2017.04.028DOI Listing
June 2017

Cytokeratin 5/6 expression, prognosis, and association with estrogen receptor α in high-grade serous ovarian carcinoma.

Hum Pathol 2017 09 13;67:30-36. Epub 2017 Apr 13.

Institute of Pathology, Charité University Hospital, Berlin 10117, Germany; Tumor Bank Ovarian Cancer Network (TOC) Berlin 10117, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2017.03.020DOI Listing
September 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine. Part 3: Technical Validation of Immunohistochemistry (IHC) Assays in Clinical IHC Laboratories.

Appl Immunohistochem Mol Morphol 2017 03;25(3):151-159

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Laboratory Hematology §Pathology, University Health Network, Toronto, ON ∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC ¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine University of Calgary, and Calgary Laboratory Services, Calgary, AB, Canada ‡Canadian Immunohistochemistry Quality Control (CIQC), Vancouver, BC, Canada/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry ∥Poundbury Cancer Institute ¶Dorset County Hospital NHS Foundation Trust, Dorchester, UK #Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK **School of Medicine, Institute of Pathology, Charité-University Hospital, Berlin, Berlin, Germany ††Griffith University, Gold Coast ‡‡RCPA Quality Assurance Program, Sydney §§Genomics For Life, Brisbane, Australia ¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA †††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy ‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands §§§Institute of Pathology, and Department of Clinical Medicine, Aalborg University, Aalborg University Hospital ∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China ††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAI.0000000000000470DOI Listing
March 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine - Part 2: Immunohistochemistry Test Performance Characteristics.

Appl Immunohistochem Mol Morphol 2017 02;25(2):79-85

*Department of Laboratory Medicine and Pathobiology, University of Toronto, Vancouver, BC, CanadaDepartment of †Laboratory Hematology§Pathology, University Health Network, Toronto, ON, Canada‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexit Testing/Immunohistochemistry∥Poundbury Cancer Institute¶Dorset County Hospital NHS Foundation Trust#Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester, UK***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK**"Rudolf-Virchow-Haus", Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany††School of Medicine, Griffith University, Gold Coast‡‡Genomics For Life, Brisbane, QLD§§RCPA Quality Assurance Program, Sydney, NSW, Australia∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg, and Division of Cancer, Department of Surgery & Cancer, Imperial College London, UK##Brigham and Women's Hospital, Harvard Medical School, Boston, MA†††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands§§§Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University, Denmark∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, AB###Department of Pathology, Beijing Friendship Hospital, Capital Medical University****CCP-IHCQC, Chinese Committee for Pathologists-Immunohistochemistry Quality Control, Beijing, China††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAI.0000000000000444DOI Listing
February 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 4: Tissue Tools for Quality Assurance in Immunohistochemistry.

Appl Immunohistochem Mol Morphol 2017 04;25(4):227-230

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Pathology §§§§Laboratory Hematology, University Health Network, Toronto, ON §§Vancouver General Hospital, University of British Columbia, Vancouver, BC ###Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB ∥∥∥∥Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ¶¶Department of Surgery & Cancer, Division of Cancer, Imperial College London ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ∥∥International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast ††Genomics For Life, Brisbane, Qld **RCPA Quality Assurance Program, Sydney, NSW, Australia ‡‡Phenopath, Seattle, WA ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA ****Keck School of Medicine, University of Southern California, Los Angeles, CA †††Center of Predictive Molecular Medicine ‡‡‡Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy §§§Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ∥∥∥Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University ¶¶¶Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ††††Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ‡‡‡‡Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAI.0000000000000469DOI Listing
April 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 1: Fit-for-Purpose Approach to Classification of Clinical Immunohistochemistry Biomarkers.

Appl Immunohistochem Mol Morphol 2017 01;25(1):4-11

*Department of Laboratory Medicine and Pathobiology, University of Toronto †Department of Pathology, University Health Network ††††Department of Laboratory Hematology, University Health Network, Toronto, ON ‡‡Vancouver General Hospital, University of British Columbia, Vancouver, BC ∥∥∥Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ∥∥Division of Cancer, Department of Surgery & Cancer, Imperial College, London, UK ##UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast **RCPA Quality Assurance Program, Sydney ††Genomics For Life, Brisbane, Australia §§International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶¶Brigham and Women's Hospital, Harvard Medical School, Boston, MA ***Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy †††Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ‡‡‡Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University §§§Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ¶¶¶Keck School of Medicine, University of Southern California, Los Angeles, CA ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing, China ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control ‡‡‡‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Vancouver, BC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAI.0000000000000451DOI Listing
January 2017

Prognostic impact of HER3 based on protein and mRNA expression in high-grade serous ovarian carcinoma.

Virchows Arch 2017 Feb 2;470(2):143-151. Epub 2016 Dec 2.

Institute of Pathology, Charité Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-016-2050-6DOI Listing
February 2017

Molecular Pathology: A Requirement for Precision Medicine in Cancer.

Authors:
Manfred Dietel

Oncol Res Treat 2016 25;39(12):804-810. Epub 2016 Nov 25.

Institute of Pathology, Charité, University Medicine Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000453085DOI Listing
March 2017

Classical pathology and mutational load of breast cancer - integration of two worlds.

J Pathol Clin Res 2015 Oct 20;1(4):225-38. Epub 2015 Jul 20.

Institute of Pathology, University Hospital HeidelbergHeidelbergGermany; Fellow of the NCT Heidelberg School of Oncology (NCT-HSO)HeidelbergGermany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cjp2.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939893PMC
October 2015

Molecular driver alterations and their clinical relevance in cancer of unknown primary site.

Oncotarget 2016 Jul;7(28):44322-44329

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Medicine V, University of Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.10035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190099PMC
July 2016

Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patients.

Virchows Arch 2016 May 25;468(5):511-25. Epub 2016 Feb 25.

Laboratory of Clinical and Experimental Pathology, Pasteur Hospital, University of Nice Sophia Antipolis, 30 avenue de la voie romaine, 06002, Nice, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-016-1910-4DOI Listing
May 2016

Wilms tumor protein 1 (WT1)-- not only a diagnostic but also a prognostic marker in high-grade serous ovarian carcinoma.

Gynecol Oncol 2016 Mar 22;140(3):494-502. Epub 2015 Dec 22.

Institute of Pathology, Charité University Hospital, Berlin, Germany; Tumor Bank Ovarian Cancer Network (TOC), Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2015.12.018DOI Listing
March 2016

ALK-FISH borderline cases in non-small cell lung cancer: Implications for diagnostics and clinical decision making.

Lung Cancer 2015 Dec 23;90(3):465-71. Epub 2015 Oct 23.

Institute of Pathology, Charité Universitätsmedizin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2015.09.022DOI Listing
December 2015

Prognostic relevance of proliferation markers (Ki-67, PHH3) within the cross-relation of ERG translocation and androgen receptor expression in prostate cancer.

Pathology 2015 Dec;47(7):629-36

1Institute of Pathology, University of Bonn, Germany 2Institute of Pathology, University of Bern, Switzerland 3Institute of Pathology, Section for Prostate Cancer Research, University of Bonn 4Department of Urology, Charité - Universitätsmedizin Berlin, Berlin 5Berlin Institute for Urologic Research, Berlin 6Institute of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAT.0000000000000320DOI Listing
December 2015

PDK1 is Expressed in Ovarian Serous Carcinoma and Correlates with Improved Survival in High-grade Tumors.

Anticancer Res 2015 Nov;35(11):6329-34

Institute of Pathology, Charité, University Hospital Berlin, Berlin, Germany

View Article

Download full-text PDF

Source
November 2015

EGFR mutation status and first-line treatment in patients with stage III/IV non-small cell lung cancer in Germany: an observational study.

Cancer Epidemiol Biomarkers Prev 2015 Aug 12;24(8):1254-61. Epub 2015 Jun 12.

Department of Thoracic Oncology, Thoraxklinik at the University of Heidelberg, Heidelberg, Germany. Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-14-1149DOI Listing
August 2015

Status of estrogen receptor 1 (ESR1) gene in mastopathy predicts subsequent development of breast cancer.

Breast Cancer Res Treat 2015 Jun 16;151(3):709-15. Epub 2015 May 16.

Department of Surgery, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-015-3427-yDOI Listing
June 2015

Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in Klatskin tumor patients.

Hepatology 2015 Sep 26;62(3):841-50. Epub 2015 Jun 26.

Experimental and Clinical Research Center, Charité Universitätsmedizin Berlin, and Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hep.27885
Publisher Site
http://dx.doi.org/10.1002/hep.27885DOI Listing
September 2015

Glutathione S-transferase-pi protein expression in prostate cancer--not always a useful diagnostic tool.

Histopathology 2015 Oct 9;67(4):577-9. Epub 2015 Apr 9.

Institute of Pathology, University of Bonn, Bonn, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.12671DOI Listing
October 2015

Bone Marrow work-up: report of a pilot study.

Recent Results Cancer Res 2015 ;199:95-105

Institute for Pathology, Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-13957-9_10DOI Listing
June 2015

The combinatorial complexity of cancer precision medicine.

Oncoscience 2014 23;1(7):504-9. Epub 2014 Jul 23.

Institute of Pathology, University of Heidelberg Medical School, Heidelberg.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278319PMC
http://dx.doi.org/10.18632/oncoscience.66DOI Listing
January 2015

Human papilloma virus status of penile squamous cell carcinoma is associated with differences in tumour-infiltrating T lymphocytes.

Virchows Arch 2015 Mar 28;466(3):323-31. Epub 2014 Dec 28.

Institute of Pathology, Charité Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-014-1713-4DOI Listing
March 2015

Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers.

J Clin Oncol 2015 Mar 22;33(9):983-91. Epub 2014 Dec 22.

Carsten Denkert, Bruno V. Sinn, Berit M. Pfitzner, Wolfgang D. Schmitt, Silvia Darb-Esfahan, Stephan Wienert, Frederick Klauschen, and Manfred Dietel, Charité Universitätsmedizin Berlin; Carsten Denkert, German Cancer Consortium (DKTK); Peter Klare, Praxisklinik and Breast Center; Jens-Uwe Blohmer, St Gertrauden Krankenhaus and Charité Universitätsmedizin; Micheal Untch, Helios Klinikum Berlin-Buch, Berlin; Gunter von Minckwitz, Stephan Gade, Keyur Mehta, and Sibylle Loibl, German Breast Group, Neu-Isenburg; Gunter von Minckwitz, Women's Hospital, University of Frankfurt; Hans Tesch, Bethanien Hospital, Frankfurt; Jan C. Brase, Ralf Kronenwett, Karin Fisch, and Kristin Krappmann, Sividon Diagnostics, Cologne; Ralf Kronenwett, Heinrich-Heine University Düsseldorf, Düsseldorf; Christian Schem, Christian-Albrechts Universität zu Kiel, Kiel; Christoph Salat, Onkologische Schwerpunktpraxis, Munich; Marcus Schmidt, Johannes-Gutenberg Universität Mainz, Mainz; Sherko Kümmel, Kliniken Essen-Mitte, Essen; Peter Sinn, University of Heidelberg, Heidelberg; Christian Jakisch and Sibylle Loibl, Sana Klinikum Offenbach, Offenbach; Toralf Reimer, Klinikum Südstadt, Rostock, Germany; Sherene Loi, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia; Sherene Loi and Christos Sotiriou, Institute Jules Bordet, Brussels, Belgium; and Fabrice André, Institute Gustave Roussy, Villejuif, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2014.58.1967DOI Listing
March 2015

Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing.

Lung Cancer 2015 Feb 6;87(2):122-9. Epub 2014 Dec 6.

Institute of Pathology, Campus Charité Mitte, Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2014.11.018DOI Listing
February 2015

Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria.

J Thorac Oncol 2014 Nov;9(11):1685-92

*Institute of Pathology, Charité BERLIN, Berlin, Germany; †Institute of Pathology, University of Heidelberg, Heidelberg, Germany; ‡Department of Pathology, Aberdeen University Medical School, Aberdeen, United Kingdom; §Department of Pathology and Cytology, Karolinska University Hospital, Solna, Stockholm, Sweden; ‖Department of Pathology, University Hospital Cologne, Cologne, Germany; ¶Laboratorio de Dianas Terapeuticas, Hospital Universitario Sanchinarro, Madrid, Spain; #Institute of Pathology, Klinikum Großhadern Ludwig-Maximilians-Universität, Munich, Germany; **Institute of Pathology, UZ ANTWERPEN, Edegem, Belgium; ††Institute of Pathology, Klinikum rechts der Isar, TU, Munich, Germany; ‡‡Institute of Pathology, University Hospital Carl Gustav Carus, Dresden, Germany; §§Institute of Pathology, Universitätsspital Basel, Basel, Germany; ‖‖Institute of Pathology, HSK Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Germany; ¶¶Institute of Pathology, Universitäts Spital Zürich, Zurich, Switzerland; ##Institute of Pathology, Centre Jean Perrin, Clermont-Ferrand, France; ***Patologisk Institut, Århus Universitetshospital, Århus, Denmark; †††Pathology-Berlin, Bioptisches Institut Gemeinschaftspraxis für Pathologie, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000332DOI Listing
November 2014

Lymph node count and prognosis in colorectal cancer: the influence of examination quality.

Int J Cancer 2015 Apr 24;136(8):1957-66. Epub 2014 Sep 24.

Department of General Pathology, Institute of Pathology, Charite University Medicine Hospital, Charitéplatz 1, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.29221DOI Listing
April 2015

Multicenter ALK testing in non-small-cell lung cancer: results of a round robin test.

J Thorac Oncol 2014 Oct;9(10):1464-9

*Institute of Pathology, Humboldt University Berlin, Campus Charité Mitte, Charité Universitätsmedizin, Berlin, Germany; and †Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000307DOI Listing
October 2014

Glutamate enrichment as new diagnostic opportunity in breast cancer.

Int J Cancer 2015 Apr 4;136(7):1619-28. Epub 2014 Sep 4.

Institute of Pathology, Charité University Hospital, Berlin, Germany; German Cancer Consortium (DKTK), partner site Berlin, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.29152DOI Listing
April 2015

Boveri at 100: the life and times of Theodor Boveri.

Authors:
Manfred Dietel

J Pathol 2014 Oct;234(2):135-7

Institute of Pathology, Charité Universitätsmedizin Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/path.4410DOI Listing
October 2014

An international interpretation study using the ALK IHC antibody D5F3 and a sensitive detection kit demonstrates high concordance between ALK IHC and ALK FISH and between evaluators.

J Thorac Oncol 2014 May;9(5):631-8

*Department of Medicine, Division of Medical Oncology, University of Colorado, Aurora, Colorado; †Department of Pathology Brigham and Women's Hospital, Boston, Massachusetts; ‡Institute of Pathology, Charité University Hospital Berlin, Germany; §Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, The Netherlands; ‖Princess Margaret Hospital, University Health Network, University of Toronto, Ontario, Canada; ¶Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Kanokoden, Chikusa-ku, Nagoya, Japan; #Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio; ** Department of Pathology, University of Colorado, Aurora, Colorado; and ††University of Colorado Comprehensive Cancer Center, Aurora, Colorado.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15560864153027
Publisher Site
http://dx.doi.org/10.1097/JTO.0000000000000115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186652PMC
May 2014

KRAS mutations in codon 12 or 13 are associated with worse prognosis in pancreatic ductal adenocarcinoma.

Pancreas 2014 May;43(4):578-83

From the Departments of *Pathology, †Hematology, Oncology and Tumor Immunology, and ‡General, Visceral, and Transplantation Surgery, Charité - Universitätsmedizin Berlin, Berlin; and §Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPA.0000000000000077DOI Listing
May 2014

Interferon-stimulated gene, 15 kDa (ISG15) in ovarian high-grade serous carcinoma: prognostic impact and link to NF-κB pathway.

Int J Gynecol Pathol 2014 Jan;33(1):16-22

Institute of Pathology (S.D.-E., B.V.S., M.R., M.D., C.D.) Department of Gynecology (J.S., I.B.), Charité Campus Virchow Klinikum, Charité Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PGP.0b013e31827b25a2DOI Listing
January 2014

Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: alterations in glutamine and beta-alanine metabolism.

J Proteomics 2013 Dec 11;94:279-88. Epub 2013 Oct 11.

Institute of Pathology, Charité University Hospital, 10117 Berlin, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S187439191300511
Publisher Site
http://dx.doi.org/10.1016/j.jprot.2013.10.002DOI Listing
December 2013

Association of small foci of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) with adenocarcinoma of the lung.

Pathol Res Pract 2013 Sep 12;209(9):578-84. Epub 2013 Jul 12.

Institute of Pathology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prp.2013.06.019DOI Listing
September 2013

Mutation analysis in malignant melanoma.

J Dtsch Dermatol Ges 2013 May;11 Suppl 4:2-10

Department of Dermatology, University of Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ddg.12070_suppDOI Listing
May 2013

Histopathological regression grading matches excellently with local and regional spread after neoadjuvant therapy of rectal cancer.

Pathol Res Pract 2013 Jul 30;209(7):424-8. Epub 2013 Apr 30.

Institut für Pathologie, Charité - Universitätsmedizin Berlin, Campus Berlin Mitte, Charitéplatz 1, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prp.2013.04.009DOI Listing
July 2013

Comparison of p40 (ΔNp63) and p63 expression in prostate tissues--which one is the superior diagnostic marker for basal cells?

Histopathology 2013 Jul 13;63(1):50-6. Epub 2013 May 13.

Institute of Pathology, University Hospital of Bonn, Bonn, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.12116DOI Listing
July 2013

CognitionMaster: an object-based image analysis framework.

Diagn Pathol 2013 Feb 27;8:34. Epub 2013 Feb 27.

Institute of Pathology, Charité University Hospital Berlin, Charitéplatz 1, Berlin, 10117, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1746-1596-8-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626931PMC
February 2013

Higher cytoplasmic and nuclear poly(ADP-ribose) polymerase expression in familial than in sporadic breast cancer.

Virchows Arch 2012 Oct 12;461(4):425-31. Epub 2012 Sep 12.

Radboud University Nijmegen Medical Centre, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-012-1311-2DOI Listing
October 2012

Down-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancer.

Histopathology 2012 Oct;61(4):552-61

Institute of Pathology, Charité University Hospital, Berlin, GermanyDepartment of Molecular Biology, National Cancer Institute, University of Gezira, Wad Medani, SudanInstitute of Pathology, University Hospital and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2559.2011.04110.xDOI Listing
October 2012