Manel Esteller

Manel Esteller

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Manel Esteller

Publications by authors named "Manel Esteller"

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DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load.

Nat Commun 2019 Sep 19;10(1):4278. Epub 2019 Sep 19.

Department of Bio and Brain Engineering, KAIST, Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1038/s41467-019-12159-9DOI Listing
September 2019

Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects.

Neuroimage Clin 2019 Aug 16;24:101983. Epub 2019 Aug 16.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742967PMC
August 2019

Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer.

Breast Cancer Res 2019 07 5;21(1):79. Epub 2019 Jul 5.

New Therapeutics Targets Lab (TargetsLab), Department of Medical Sciences, University of Girona, E-17071, Girona, Catalonia, Spain.

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http://dx.doi.org/10.1186/s13058-019-1160-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612099PMC
July 2019

Disruption of Long Noncoding RNAs Targets Cancer Hallmark Pathways in Lung Tumorigenesis.

Cancer Res 2019 Jun;79(12):3028-3030

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0910DOI Listing
June 2019

CpG Islands in Cancer: Heads, Tails, and Sides.

Methods Mol Biol 2018 ;1766:49-80

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/978-1-4939-7768-0_4DOI Listing
May 2019

Infinium DNA Methylation Microarrays on Formalin-Fixed, Paraffin-Embedded Samples.

Methods Mol Biol 2018 ;1766:83-107

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/978-1-4939-7768-0_5DOI Listing
May 2019

Germline variation in O-methylguanine-DNA methyltransferase (MGMT) as cause of hereditary colorectal cancer.

Cancer Lett 2019 Apr 21;447:86-92. Epub 2019 Jan 21.

Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain; Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell), IDIBELL, Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.01.019DOI Listing
April 2019

APOE-ε4 risk variant for Alzheimer's disease modifies the association between cognitive performance and cerebral morphology in healthy middle-aged individuals.

Neuroimage Clin 2019 8;23:101818. Epub 2019 Apr 8.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain; Universitat Pompeu Fabra, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463204PMC
April 2019

A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting .

Clin Epigenetics 2018 27;10:40. Epub 2018 Mar 27.

1Cancer Biology & Epigenetics Group - Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), F Bdg, 1st floor, Rua Dr António Bernardino de Almeida, 4200-072 Porto, Portugal.

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http://dx.doi.org/10.1186/s13148-018-0475-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870254PMC
February 2019

Clinical epigenetics: seizing opportunities for translation.

Nat Rev Genet 2019 02;20(2):109-127

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/s41576-018-0074-2DOI Listing
February 2019

Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction.

Clin Epigenetics 2019 02 26;11(1):35. Epub 2019 Feb 26.

Imprinting and Cancer Group, Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute - IDIBELL, Av. Gran Via de L'Hospotalet 199-203, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1186/s13148-019-0630-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390544PMC
February 2019

Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.

Epigenetics 2018 5;13(2):182-191. Epub 2018 Mar 5.

a Imprinting and Cancer group, Cancer Epigenetics and Biology Program (PEBC) , Institut d'Investigació Biomedica de Bellvitge (IDIBELL) , Avinguda Granvia, L'Hospitalet de Llobregat , Barcelona , Spain.

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http://dx.doi.org/10.1080/15592294.2017.1344803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873360PMC
December 2018

Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation.

Brain Pathol 2018 11 10;28(6):902-919. Epub 2018 Apr 10.

Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), 08908 L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1111/bpa.12595DOI Listing
November 2018

Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins.

Biosens Bioelectron 2018 Nov 15;120:47-54. Epub 2018 Aug 15.

Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193 Barcelona, Spain; CIBER-BBN Networking Center on Bioengineering, Biomaterials and Nanomedicine, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2018.08.027DOI Listing
November 2018

Lung cancer epigenetics: From knowledge to applications.

Semin Cancer Biol 2018 08 14;51:116-128. Epub 2017 Sep 14.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908 L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain and Centro de Investigación Biomédica en Red de Cáncer (CIBERONC); Instituciò Catalana de Recerca i Estudis Avançats (ICREA), 08010, Barcelona, Catalonia, Spain; Department of Physiological Sciences II, School of Medicine, University of Barcelona, 08036, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2017.09.005DOI Listing
August 2018

Introduction: Epigenetics in cancer.

Semin Cancer Biol 2018 08 7;51:iv-v. Epub 2018 Jul 7.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X183008
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http://dx.doi.org/10.1016/j.semcancer.2018.07.002DOI Listing
August 2018

Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease.

Alzheimers Dement 2018 07 28;14(7):902-912. Epub 2018 Mar 28.

Barcelonabeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Catalonia, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.01.016DOI Listing
July 2018

SnapShot: Messenger RNA Modifications.

Cell 2018 07;174(2):498-498.e1

Bellvitge Biomedical Research Institute, Barcelona, Spain; Physiological Sciences Department, University of Barcelona, Spain; Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cell.2018.06.046DOI Listing
July 2018

MicroRNAs and Epigenetics.

Adv Cancer Res 2017 4;135:189-220. Epub 2017 Aug 4.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain; School of Medicine and Health Sciences, University of Barcelona (UB), Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/bs.acr.2017.06.003DOI Listing
June 2018

Interplay between long non-coding RNAs and epigenetic machinery: emerging targets in cancer?

Philos Trans R Soc Lond B Biol Sci 2018 06;373(1748)

Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908 Barcelona, Spain

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http://dx.doi.org/10.1098/rstb.2017.0074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915718PMC
June 2018

Circular RNA CpG island hypermethylation-associated silencing in human cancer.

Oncotarget 2018 Jun 26;9(49):29208-29219. Epub 2018 Jun 26.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.18632/oncotarget.25673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044373PMC
June 2018

PM20D1 is a quantitative trait locus associated with Alzheimer's disease.

Nat Med 2018 05 7;24(5):598-603. Epub 2018 May 7.

Laboratory of Neuroepigenetics, Brain Mind Institute, Faculty of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41591-018-0013-yDOI Listing
May 2018

Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice.

Cell Rep 2018 05;23(6):1665-1677

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908 L'Hospitalet, Barcelona, Catalonia, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain; Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), 08907 Catalonia, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183053
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http://dx.doi.org/10.1016/j.celrep.2018.04.010DOI Listing
May 2018

Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders.

Clin Epigenetics 2017 29;9:67. Epub 2017 Jun 29.

Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), 3rd Floor, Hospital Duran i Reynals, Av. Gran Via 199-203, 08908L'Hospitalet, Barcelona, Catalonia Spain.

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http://dx.doi.org/10.1186/s13148-017-0365-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493012PMC
April 2018

An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N-Methyltransferase Gene Expression.

Mol Nutr Food Res 2018 Apr 24:e1700933. Epub 2018 Apr 24.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona, Girona, 77190 Spain, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Madrid, 28029, Spain.

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http://dx.doi.org/10.1002/mnfr.201700933DOI Listing
April 2018

Non-coding RNAs, epigenetics, and cancer: tying it all together.

Cancer Metastasis Rev 2018 03;37(1):55-73

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, 08908, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/s10555-017-9715-8DOI Listing
March 2018

CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8 T Cell-Relevant Genes.

Cancer Immunol Res 2018 01 13;6(1):69-78. Epub 2017 Nov 13.

Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0159DOI Listing
January 2018

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.

Nat Commun 2018 01 9;9(1):101. Epub 2018 Jan 9.

Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Av. Gran Via de l'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat (Barcelona), Spain.

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http://dx.doi.org/10.1038/s41467-017-02586-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760577PMC
January 2018

TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes.

Stem Cell Reports 2017 12 30;9(6):2065-2080. Epub 2017 Nov 30.

Laboratory for Gene Therapy, Department of Cancer Immunology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785758PMC
December 2017

Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary.

Nat Rev Clin Oncol 2017 Nov 4;14(11):682-694. Epub 2017 Jul 4.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Avinguda Gran Via 199-203, 08908 L'Hospitalet del Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1038/nrclinonc.2017.97DOI Listing
November 2017

Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization.

Cell Rep 2017 Nov;21(8):2048-2057

Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Av. Gran Via de l'Hospitalet, 199-203, 08907- L'Hospitalet de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.092DOI Listing
November 2017

The Epigenomic Revolution in Breast Cancer: From Single-Gene to Genome-Wide Next-Generation Approaches.

Am J Pathol 2017 Oct 19;187(10):2163-2174. Epub 2017 Jul 19.

Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Spain; Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.07.002DOI Listing
October 2017

Stem Cell Technology for (Epi)genetic Brain Disorders.

Adv Exp Med Biol 2017 ;978:443-475

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Duran i Reynals Hospital, 3rd floor, Gran Via de L'Hospitalet 199-203, L'Hospitalet de Llobregat, Barcelona, Catalonia, 08908, Spain.

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http://dx.doi.org/10.1007/978-3-319-53889-1_23DOI Listing
September 2017

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features.

Gastroenterology 2017 09 15;153(3):812-826. Epub 2017 Jun 15.

Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology, Recanati Miller Transplantation Institute), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Liver Cancer Translational Research Laboratory, BCLC, Liver Unit, CIBEREHD, IDIBAPS, Hospital Clinic, University of Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.06.007DOI Listing
September 2017

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors.

Nat Commun 2017 09 7;8(1):467. Epub 2017 Sep 7.

Imprinting and Cancer group, Cancer Epigenetic and Biology Program (PEBC), Institut d'Investigació Biomedica de Bellvitge (IDIBELL), Avinguda Granvia, L'Hospitalet de Llobregat, 08907, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41467-017-00639-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589900PMC
September 2017

Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update.

Open Biol 2017 09;7(9)

Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain

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http://dx.doi.org/10.1098/rsob.170152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627056PMC
September 2017

Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer.

Oncotarget 2017 Aug 29;8(31):51621-51629. Epub 2017 May 29.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.18632/oncotarget.18255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584274PMC
August 2017

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells.

Mol Cancer Ther 2017 07 10;16(7):1366-1376. Epub 2017 Apr 10.

Genes and Cancer Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0104DOI Listing
July 2017

Obesity and menopause modify the epigenomic profile of breast cancer.

Endocr Relat Cancer 2017 07 25;24(7):351-363. Epub 2017 Apr 25.

Cancer Epigenetics and Biology Program (PEBC)Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain

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http://dx.doi.org/10.1530/ERC-16-0565DOI Listing
July 2017

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

Synapse 2017 06 6;71(6). Epub 2017 Feb 6.

School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Brain Mind Institute, Lausanne, CH-1015, Switzerland.

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http://dx.doi.org/10.1002/syn.21959DOI Listing
June 2017

Bromodomain inhibitors and cancer therapy: From structures to applications.

Epigenetics 2017 05 2;12(5):323-339. Epub 2016 Dec 2.

a Cancer Epigenetics and Biology Program (PEBC) , Bellvitge Biomedical Research Institute (IDIBELL) , Barcelona , Catalonia , Spain.

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http://dx.doi.org/10.1080/15592294.2016.1265710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453193PMC
May 2017

Epigenetic drugs: More than meets the eye.

Authors:
Manel Esteller

Epigenetics 2017 05;12(5):307

a Cancer Epigenetics and Biology Program (PEBC) , Bellvitge Biomedical Research Institute (IDIBELL) , Barcelona , Catalonia , Spain.

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http://dx.doi.org/10.1080/15592294.2017.1322881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453189PMC
May 2017

The Epitranscriptome of Noncoding RNAs in Cancer.

Cancer Discov 2017 04 20;7(4):359-368. Epub 2017 Mar 20.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-16-1292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997407PMC
April 2017

Journal club: epigenetic profiling to classify cancer of unknown primary - Authors' reply.

Lancet Oncol 2017 03 2;18(3):e131. Epub 2017 Mar 2.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona 08908, Spain; Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona 08036, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30105-5DOI Listing
March 2017

Downregulation of miR-130b~301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer.

J Hematol Oncol 2017 02 6;10(1):43. Epub 2017 Feb 6.

Cancer Biology & Epigenetics Group-Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), Rua Dr António Bernardino de Almeida, 4200-072, Porto, Portugal.

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http://dx.doi.org/10.1186/s13045-017-0415-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294724PMC
February 2017

The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site.

Sci Rep 2017 01 31;7:41635. Epub 2017 Jan 31.

Institute of Biocomputation and Physics of Complex Systems (BIFI), Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Universidad de Zaragoza, Zaragoza, 50018, Spain.

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http://dx.doi.org/10.1038/srep41635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282554PMC
January 2017

MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors.

Mol Cancer 2017 01 31;16(1):26. Epub 2017 Jan 31.

Cancer Biology and Epigenetics Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), Research Center-LAB 3, F Bdg., 1st floor, Rua Dr António Bernardino de Almeida, 4200-072, Porto, Portugal.

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http://dx.doi.org/10.1186/s12943-017-0604-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282784PMC
January 2017

Extraordinary Cancer Epigenomics: Thinking Outside the Classical Coding and Promoter Box.

Trends Cancer 2016 10 13;2(10):572-584. Epub 2016 Sep 13.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Avinguda Gran Via de L'Hospitalet 199-203, L'Hospitalet del Llobregat, Barcelona, Catalonia, Spain; Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain; Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2016.08.004DOI Listing
October 2016