Mandy L Ballinger

Mandy L Ballinger

UNVERIFIED PROFILE

Are you Mandy L Ballinger?   Register this Author

Register author
Mandy L Ballinger

Mandy L Ballinger

Publications by authors named "Mandy L Ballinger"

Are you Mandy L Ballinger?   Register this Author

50Publications

951Reads

12Profile Views

Who should access germline genome sequencing? A mixed methods study of patient views.

Clin Genet 2019 Nov 1. Epub 2019 Nov 1.

Faculty of Medicine and Health, Sydney School of Public Health, Sydney Health Ethics, University of Sydney, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cge.13664DOI Listing
November 2019

Therapeutic implications of germline genetic findings in cancer.

Nat Rev Clin Oncol 2019 06;16(6):386-396

Cancer Division, Garvan Institute of Medical Research, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41571-019-0179-3DOI Listing
June 2019

A quantitative model to predict pathogenicity of missense variants in the TP53 gene.

Hum Mutat 2019 06 18;40(6):788-800. Epub 2019 Mar 18.

Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.23739DOI Listing
June 2019

Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts.

BMC Med Genet 2019 05 3;20(1):69. Epub 2019 May 3.

The Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health Sciences, Curtin University and Faculty of Health and Medical Sciences, M409 The University of Western Australia, 35 Stirling Hwy, Crawley, 6009, Western Australia.

View Article

Download full-text PDF

Source
https://bmcmedgenet.biomedcentral.com/articles/10.1186/s1288
Publisher Site
http://dx.doi.org/10.1186/s12881-019-0808-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499942PMC
May 2019

Diagnosis of fusion genes using targeted RNA sequencing.

Nat Commun 2019 03 27;10(1):1388. Epub 2019 Mar 27.

Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09374-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437215PMC
March 2019

Translating genomic risk into an early detection strategy for sarcoma.

Genes Chromosomes Cancer 2019 02 29;58(2):130-136. Epub 2018 Nov 29.

Cancer Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22697DOI Listing
February 2019

Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk.

J Genet Couns 2018 09 17;27(5):1055-1066. Epub 2018 Feb 17.

The Kinghorn Cancer Centre and Cancer Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10897-018-0223-yDOI Listing
September 2018

Surveillance in Germline TP53 Mutation Carriers Utilizing Whole-Body Magnetic Resonance Imaging.

JAMA Oncol 2017 12;3(12):1735-1736

Cancer Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoncol.2017.1355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824268PMC
December 2017

Estimating Mutation Carrier Probability in Families with Li-Fraumeni Syndrome Using LFSPRO.

Cancer Epidemiol Biomarkers Prev 2017 06 30;26(6):837-844. Epub 2017 Jan 30.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://cebp.aacrjournals.org/lookup/doi/10.1158/1055-9965.EP
Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-16-0695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457344PMC
June 2017

Sarcoma and germ-line DICER1 mutations - Authors' reply.

Lancet Oncol 2016 11;17(11):e471

Garvan Institute of Medical Research, The Kinghorn Cancer Centre and Cancer Division, Darlinghurst, NSW 2010, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(16)30527-7DOI Listing
November 2016

Diagnosis and Management of Hereditary Sarcoma.

Recent Results Cancer Res 2016 ;205:169-89

The Kinghorn Cancer Centre & Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-29998-3_10DOI Listing
July 2016

International survey of awareness of genetic risk in the clinical sarcoma community.

Asia Pac J Clin Oncol 2016 Jun 29;12(2):133-42. Epub 2016 Feb 29.

Department of Cancer Medicine, The Chris O'Brien Lifehouse, Sydney Medical School, University of Sydney, Camperdown, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajco.12457DOI Listing
June 2016

Timing and context: important considerations in the return of genetic results to research participants.

J Community Genet 2016 Jan 26;7(1):11-20. Epub 2015 May 26.

Familial Cancer Centre, Peter MacCallum Cancer Centre, East Melbourne, VIC, 3002, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12687-015-0231-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715816PMC
January 2016

Surveillance recommendations for patients with germline TP53 mutations.

Curr Opin Oncol 2015 Jul;27(4):332-7

aSir Peter MacCallum Department of Oncology, University of Melbourne bResearch Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia cHereditary Cancer Program, BC Cancer Agency, Vancouver, British Columbia, Canada dThe Kinghorn Cancer Centre and Cancer Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/CCO.0000000000000200DOI Listing
July 2015

Clinical implications of genomics for cancer risk genetics.

Lancet Oncol 2015 Jun 27;16(6):e303-8. Epub 2015 May 27.

Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia; Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(15)70026-4DOI Listing
June 2015

Etiologic, environmental and inherited risk factors in sarcomas.

J Surg Oncol 2015 Apr 21;111(5):490-5. Epub 2014 Oct 21.

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia; Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jso.23809
Publisher Site
http://dx.doi.org/10.1002/jso.23809DOI Listing
April 2015

Li-Fraumeni syndrome: cancer risk assessment and clinical management.

Nat Rev Clin Oncol 2014 May 18;11(5):260-71. Epub 2014 Mar 18.

The Familial Cancer Centre, Sir Peter MacCallum Department of Oncology, University of Melbourne, Peter MacCallum Cancer Centre, East Melbourne, VIC 3002, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2014.41DOI Listing
May 2014

Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans.

Cardiovasc Pathol 2013 Mar-Apr;22(2):146-55. Epub 2012 Sep 21.

Discipline of Pharmacy, School of Medical Sciences and Diabetes Complications Group, Health Innovations Research Institute, RMIT University, Melbourne, Victoria 3083, Australia.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10548807120009
Publisher Site
http://dx.doi.org/10.1016/j.carpath.2012.07.002DOI Listing
September 2013

Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells.

J Pharm Pharmacol 2013 Jul 24;65(7):1055-63. Epub 2013 Apr 24.

Discipline of Pharmacy, School of Medical Sciences, Diabetes Complications Group, Health Innovations Research Institute, Melbourne, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jphp.12064DOI Listing
July 2013

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation.

Arch Biochem Biophys 2012 Sep 7;525(1):25-31. Epub 2012 Jun 7.

Discipline of Pharmacy, School of Medical Sciences and Diabetes Complications Group, Health Innovations Research Institute, RMIT University, Bundoora, VIC 3083, Australia.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00039861120023
Publisher Site
http://dx.doi.org/10.1016/j.abb.2012.05.025DOI Listing
September 2012

An increased incidence of Hodgkin's lymphoma in patients with adult-onset sarcoma.

Clin Sarcoma Res 2012 Jan 9;2(1). Epub 2012 Jan 9.

Sarcoma Genomics and Genetics Laboratory, Research Division, The Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2045-3329-2-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351710PMC
January 2012

Biosynthesis of natural and hyperelongated chondroitin sulfate glycosaminoglycans: new insights into an elusive process.

Open Biochem J 2008 18;2:135-42. Epub 2008 Nov 18.

Diabetes and Cell Biology Laboratory, Vascular and Hypertension Division, BakerIDI Heart and Diabetes Institute, Melbourne, VIC, Australia 3004 and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1874091X00802010135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627520PMC
July 2011

PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL.

Endocrinology 2010 Sep 7;151(9):4356-67. Epub 2010 Jul 7.

Diabetes and Cell Biology Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St. Kilda Road Central, Melbourne, Victoria 8008, Australia.

View Article

Download full-text PDF

Source
https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
Publisher Site
http://dx.doi.org/10.1210/en.2010-0027DOI Listing
September 2010

TGF-beta stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2.

Cell Mol Life Sci 2010 Jun 7;67(12):2077-90. Epub 2010 Mar 7.

Diabetes and Cell Biology Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-010-0315-9DOI Listing
June 2010

Characterisation of Ki11502 as a potent inhibitor of PDGF beta receptor-mediated proteoglycan synthesis in vascular smooth muscle cells.

Eur J Pharmacol 2010 Jan 8;626(2-3):186-92. Epub 2009 Oct 8.

Diabetes and Cell Biology of Diabetes Laboratory, BakerIDI Heart and Diabetes Institute, Commercial Road, Melbourne, Victoria 3141, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejphar.2009.09.066DOI Listing
January 2010

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation.

Arch Physiol Biochem 2009 Jul;115(3):147-54

BakerIDI Heart and Diabetes Institute, Diabetes and Cell Biology Laboratory, Melbourne, VIC, 3004, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13813450903110754DOI Listing
July 2009

p38 MAP kinase mediated proteoglycan synthesis as a target for the prevention of atherosclerosis.

Cardiovasc Hematol Disord Drug Targets 2008 Dec;8(4):287-92

Diabetes and Cell Biology Laboratory, BakerIDI Heart and Diabetes Institute, Postal, St. Kilda Rd Central, PO Box 6492, Melbourne, VIC 8008, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/187152908786786205DOI Listing
December 2008

Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle.

J Biol Chem 2008 Mar 25;283(12):7844-52. Epub 2008 Jan 25.

Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, Victoria 3004, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M703125200DOI Listing
March 2008

Phosphorylated troglitazone activates PPARgamma and inhibits vascular smooth muscle cell proliferation and proteoglycan synthesis.

J Cardiovasc Pharmacol 2008 Mar;51(3):274-9

Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FJC.0b013e3181626ce7DOI Listing
March 2008

Vascular wall proteoglycan synthesis and structure as a target for the prevention of atherosclerosis.

Vasc Health Risk Manag 2007 ;3(1):117-24

Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, Australia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994044PMC
August 2007

Regulation of the atherogenic properties of vascular smooth muscle proteoglycans by oral anti-hyperglycemic agents.

J Diabetes Complications 2007 Mar-Apr;21(2):108-17

Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, PO Box 6492, Melbourne, Victoria 8008, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdiacomp.2006.03.003DOI Listing
July 2007

Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells.

Kidney Int 2005 Dec;68(6):2756-65

Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, The Alfred Hospital, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1523-1755.2005.00746.xDOI Listing
December 2005

New approaches to regulating the chondroitin/dermatan sulfate glycosaminoglycan component of the vascular extracellular matrix.

ScientificWorldJournal 2005 Jul;5:515-20

Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1100/tsw.2005.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936516PMC
July 2005