Manabu Ohyama

Manabu Ohyama

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Manabu Ohyama

Publications by authors named "Manabu Ohyama"

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Use of trichoscopy for the diagnosis of alopecia areata coexisting with primary scarring alopecia in a female hair loss patient.

J Dermatol 2019 May 7;46(5):418-421. Epub 2019 Mar 7.

Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan.

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http://doi.wiley.com/10.1111/1346-8138.14841
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http://dx.doi.org/10.1111/1346-8138.14841DOI Listing
May 2019

30 Years (and More) of Hair Research Societies.

J Am Acad Dermatol 2019 Apr 17. Epub 2019 Apr 17.

The Society for Hair Science Research (Japan), Okubo 2-4-12, Shinjuku-ku, Shunkosha, Co. 169-0072 Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jaad.2019.04.028DOI Listing
April 2019

Use of human intra-tissue stem/progenitor cells and induced pluripotent stem cells for hair follicle regeneration.

Authors:
Manabu Ohyama

Inflamm Regen 2019 25;39. Epub 2019 Feb 25.

Department of Dermatology, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611 Japan.

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http://dx.doi.org/10.1186/s41232-019-0093-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388497PMC
February 2019

Chronological observation of surgically-treated granuloma faciale implies the necessity of circumspect management for perinasal nodular subset.

J Dermatol 2018 Sep 15;45(9):1122-1125. Epub 2018 Jun 15.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.14507DOI Listing
September 2018

Color-transition sign: A useful trichoscopic finding for differentiating alopecia areata incognita from telogen effluvium.

J Dermatol 2018 Aug 6;45(8):e224-e225. Epub 2018 Mar 6.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

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http://doi.wiley.com/10.1111/1346-8138.14274
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http://dx.doi.org/10.1111/1346-8138.14274DOI Listing
August 2018

Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss.

J Dermatol Sci 2018 Jul 6;91(1):43-51. Epub 2018 Apr 6.

Department of Dermatology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2018.04.001DOI Listing
July 2018

Azathioprine monotherapy in autoimmune blistering diseases: A feasible option for mild to moderate cases.

J Dermatol 2018 Mar 18;45(3):334-339. Epub 2017 Dec 18.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.14173DOI Listing
March 2018

Case of phenylephrine hydrochloride-induced periorbital contact dermatitis with fulminant keratoconjunctivitis causing pseudomembrane formation.

J Dermatol 2018 Feb 6;45(2):e27-e28. Epub 2017 Oct 6.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.14077DOI Listing
February 2018

Immunohistochemical dissection of cystic panfolliculoma focusing on the expression of multiple hair follicle lineage markers with an insight into the pathogenesis.

J Cutan Pathol 2017 Oct 24;44(10):861-866. Epub 2017 Jul 24.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/cup.12992DOI Listing
October 2017

Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice.

Cell Rep 2017 08;20(7):1513-1524

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan; Japan Agency for Medical Research and Development, CREST, Chiyoda-ku, Tokyo 100-0004, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.07.057DOI Listing
August 2017

The ovariectomized mouse simulates the pathophysiology of postmenopausal female pattern hair loss.

J Dermatol Sci 2017 Jul 7;87(1):79-82. Epub 2017 Apr 7.

Department of Dermatology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2017.04.002DOI Listing
July 2017

Cutaneous Metaplastic Synovial Cyst: Case Report and Literature Review from the Dermatological Point of View.

Keio J Med 2017 Mar 17;66(1):9-13. Epub 2016 Jun 17.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.2302/kjm.2016-0002-CRDOI Listing
March 2017

Differential X Chromosome Inactivation Patterns during the Propagation of Human Induced Pluripotent Stem Cells.

Keio J Med 2017 Mar 20;66(1):1-8. Epub 2017 Jan 20.

Department of Physiology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.2302/kjm.2016-0015-OADOI Listing
March 2017

LNGFRTHY-1 human pluripotent stem cell-derived neural crest-like cells have the potential to develop into mesenchymal stem cells.

Differentiation 2016 12 10;92(5):270-280. Epub 2016 May 10.

Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.diff.2016.04.003DOI Listing
December 2016

Application of electron microscopic analysis and fluorescent in situ hybridization technique for the successful diagnosis of extraskeletal Ewing's sarcoma.

J Dermatol 2015 Sep 11;42(9):893-6. Epub 2015 May 11.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12930DOI Listing
September 2015

Exploring the biology of the nail: An intriguing but less-investigated skin appendage.

J Dermatol Sci 2015 Sep 5;79(3):187-93. Epub 2015 May 5.

Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2015.04.011DOI Listing
September 2015

Programming of induced pluripotent stem cells for hair follicle regeneration.

Authors:
Manabu Ohyama

Nihon Rinsho 2015 Jun;73 Suppl 5:193-8

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June 2015

Case of angiosarcoma on the abdominal wall, an extremely rare variant, putatively shared the pathogenesis with Stewart-Treves syndrome.

J Dermatol 2015 Apr 21;42(4):426-7. Epub 2015 Feb 21.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12809DOI Listing
April 2015

Chronology of confluent and reticulated papillomatosis: spontaneous regression in a case after long-term follow-up may imply transient nature of the condition.

J Dermatol 2015 Mar 23;42(3):335-6. Epub 2015 Jan 23.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12776DOI Listing
March 2015

Detailed clinicopathological characterization of progressive alopecia areata patients treated with i.v. corticosteroid pulse therapy toward optimization of inclusion criteria.

J Dermatol 2014 Nov 8;41(11):957-63. Epub 2014 Oct 8.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://doi.wiley.com/10.1111/1346-8138.12637
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http://dx.doi.org/10.1111/1346-8138.12637DOI Listing
November 2014

Histopathological investigation of clinically non-affected perilesional scalp in alopecias detected unexpected spread of disease activities.

J Dermatol 2014 Sep 25;41(9):802-7. Epub 2014 Aug 25.

Department of Dermatology, Keio University School of Medicine, Tokyo; Division of Dermatology, Kawasaki Municipal Hospital, Kawasaki, Japan.

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http://dx.doi.org/10.1111/1346-8138.12591DOI Listing
September 2014

Follicular microhemorrhage: a unique dermoscopic sign for the detection of coexisting trichotillomania in alopecia areata.

J Dermatol 2014 Jun 10;41(6):518-20. Epub 2014 May 10.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12500DOI Listing
June 2014

Histopathological insights into hair loss in Cronkhite-Canada syndrome: diffuse anagen-telogen conversion precedes clinical hair loss progression.

Australas J Dermatol 2014 May 29;55(2):145-8. Epub 2013 May 29.

Division of Dermatology, Federation of National Public Service Personal Mutual Aid Associations Tachikawa Hospital, Tokyo, Japan; Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/ajd.12068DOI Listing
May 2014

Use of cyclosporin A for successful management of steroid-resistant Sweet's syndrome patient with possible myelodysplastic syndrome.

J Dermatol 2014 May 19;41(5):465-6. Epub 2014 Apr 19.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12469DOI Listing
May 2014

Promise of human induced pluripotent stem cells in skin regeneration and investigation.

J Invest Dermatol 2014 Mar 17;134(3):605-609. Epub 2013 Oct 17.

Department of Physiology, Keio University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.376DOI Listing
March 2014

Rheumatoid neutrophilic dermatosis with tense blister formation: a case report and review of the literature.

Australas J Dermatol 2014 Feb 25;55(1):e12-4. Epub 2012 Oct 25.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1440-0960.2012.00963.xDOI Listing
February 2014

Unusually extensive disseminated herpes zoster with multiple ulcer formation in a methotrexate-treated rheumatoid arthritis patient.

J Dermatol 2014 Feb 16;41(2):181-2. Epub 2014 Jan 16.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12377DOI Listing
February 2014

Hapten-induced lymphadenosis benigna cutis secondary to squaric acid dibutylester sensitization for alopecia areata.

J Dermatol 2014 Feb;41(2):182-3

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12376DOI Listing
February 2014

Immune response involving the bulge region in addition to telogen conversion contributes to hair loss in a case of atypical drug-induced hypersensitivity syndrome.

J Dermatol 2013 Nov 16;40(11):928-9. Epub 2013 Oct 16.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12271DOI Listing
November 2013

Improvement of mucocutaneous involvement of immunoglobulin light chain amyloidosis after chemotherapy and hematopoietic stem cell transplantation for multiple myeloma.

J Dermatol 2013 Sep 16;40(9):768-9. Epub 2013 Jul 16.

Department of Dermatology, Department of Medicine, School of Medicine, Keio University, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12233DOI Listing
September 2013

Ectopic expression of epidermal antigens renders the lung a target organ in paraneoplastic pemphigus.

J Immunol 2013 Jul 31;191(1):83-90. Epub 2013 May 31.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.4049/jimmunol.1203536DOI Listing
July 2013

Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo.

J Invest Dermatol 2013 Jun 15;133(6):1479-88. Epub 2013 Jan 15.

Department of Dermatology, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153628
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http://dx.doi.org/10.1038/jid.2013.7DOI Listing
June 2013

Strategies to enhance epithelial-mesenchymal interactions for human hair follicle bioengineering.

J Dermatol Sci 2013 May 28;70(2):78-87. Epub 2013 Feb 28.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2013.02.004DOI Listing
May 2013

CD200-expressing human basal cell carcinoma cells initiate tumor growth.

Proc Natl Acad Sci U S A 2013 Jan 4;110(4):1434-9. Epub 2013 Jan 4.

Department of Dermatology and Wound Healing, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1211655110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557049PMC
January 2013

A missense mutation within the helix initiation motif of the keratin K71 gene underlies autosomal dominant woolly hair/hypotrichosis.

J Invest Dermatol 2012 Oct 17;132(10):2342-2349. Epub 2012 May 17.

Laboratory of Genetic Skin Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1535494
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http://dx.doi.org/10.1038/jid.2012.154DOI Listing
October 2012

Isolation and characterization of stem cell-enriched human and canine hair follicle keratinocytes.

Methods Mol Biol 2012 ;879:389-401

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1007/978-1-61779-815-3_24DOI Listing
September 2012

Restoration of the intrinsic properties of human dermal papilla in vitro.

J Cell Sci 2012 Sep 23;125(Pt 17):4114-25. Epub 2012 May 23.

Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1242/jcs.105700DOI Listing
September 2012

Brief report: requirement of TACE/ADAM17 for hair follicle bulge niche establishment.

Stem Cells 2012 Aug;30(8):1781-5

Department of Dermatology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/stem.1153DOI Listing
August 2012

Primary cicatricial alopecia: recent advances in understanding and management.

Authors:
Manabu Ohyama

J Dermatol 2012 Jan 21;39(1):18-26. Epub 2011 Nov 21.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1346-8138.2011.01416.xDOI Listing
January 2012

Molecular biological and immunohistological characterization of canine dermal papilla cells and the evaluation of culture conditions.

Vet Dermatol 2011 Oct 17;22(5):414-22. Epub 2011 Mar 17.

Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1111/j.1365-3164.2011.00964.xDOI Listing
October 2011

A Japanese case of ichthyosis follicularis with atrichia and photophobia syndrome with an MBTPS2 mutation.

J Hum Genet 2011 Mar 23;56(3):250-2. Epub 2010 Dec 23.

Department of Pediatrics, Ibaraki Prefectural University of Health Sciences, Ibaraki, Japan.

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http://www.nature.com/articles/jhg2010163
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http://dx.doi.org/10.1038/jhg.2010.163DOI Listing
March 2011

Generation of human melanocytes from induced pluripotent stem cells.

PLoS One 2011 Jan 13;6(1):e16182. Epub 2011 Jan 13.

Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016182PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020956PMC
January 2011

Canine follicle stem cell candidates reside in the bulge and share characteristic features with human bulge cells.

J Invest Dermatol 2010 Aug 1;130(8):1988-95. Epub 2010 Apr 1.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1038/jid.2010.68DOI Listing
August 2010

The 1st JSID Kisaragi Juku: The junior tutors' perspective.

J Dermatol Sci 2010 Jun 24;58(3):167-70. Epub 2010 Apr 24.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawara, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2010.04.002DOI Listing
June 2010

The mesenchymal component of hair follicle neogenesis: background, methods and molecular characterization.

Exp Dermatol 2010 Feb 23;19(2):89-99. Epub 2009 Jul 23.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1600-0625.2009.00935.xDOI Listing
February 2010

A gene therapy approach for long-term normalization of blood pressure in hypertensive mice by ANP-secreting human skin grafts.

Proc Natl Acad Sci U S A 2010 Jan 11;107(3):1178-83. Epub 2010 Jan 11.

Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1908, USA.

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http://dx.doi.org/10.1073/pnas.0908882107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824301PMC
January 2010

Canine hair-follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells.

Vet Dermatol 2009 Oct;20(5-6):338-46

Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan.

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http://dx.doi.org/10.1111/j.1365-3164.2009.00815.xDOI Listing
October 2009

The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice.

Proc Natl Acad Sci U S A 2009 Jun 26;106(23):9292-7. Epub 2009 May 26.

Division of Mammalian Development and Mammalian Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan.

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http://dx.doi.org/10.1073/pnas.0808324106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695080PMC
June 2009

Hair follicle bulge: a fascinating reservoir of epithelial stem cells.

Authors:
Manabu Ohyama

J Dermatol Sci 2007 May 5;46(2):81-9. Epub 2007 Jan 5.

Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2006.12.002DOI Listing
May 2007

William J. Cunliffe Scientific Awards. Advances in the study of stem-cell-enriched hair follicle bulge cells: a review featuring characterization and isolation of human bulge cells.

Authors:
Manabu Ohyama

Dermatology 2007 ;214(4):342-51

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1159/000100889DOI Listing
May 2007

Gene ontology analysis of human hair follicle bulge molecular signature.

J Dermatol Sci 2007 Feb 30;45(2):147-50. Epub 2006 Oct 30.

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http://dx.doi.org/10.1016/j.jdermsci.2006.09.009DOI Listing
February 2007

Bone marrow-derived keratinocytes are not detected in normal skin and only rarely detected in wounded skin in two different murine models.

Exp Hematol 2006 May;34(5):672-9

Dermatology Branch, National Cancer Institute, Office of Research Service, National Institutes of Health, Bethesda, MD 20892-1908, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0301472X0600063
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http://dx.doi.org/10.1016/j.exphem.2006.02.002DOI Listing
May 2006

Gene delivery to the hair follicle.

J Investig Dermatol Symp Proc 2003 Oct;8(2):204-6

Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1908, USA.

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http://dx.doi.org/10.1046/j.1087-0024.2003.00810.xDOI Listing
October 2003

Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris.

J Invest Dermatol 2002 Jan;118(1):199-204

Department of Dermatology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1046/j.0022-202x.2001.01643.xDOI Listing
January 2002