Man-Wah Tan

Man-Wah Tan

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Man-Wah Tan

Man-Wah Tan

Publications by authors named "Man-Wah Tan"

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A Tet-Off gene expression system for validation of antifungal drug targets in a murine invasive pulmonary aspergillosis model.

Sci Rep 2018 01 11;8(1):443. Epub 2018 Jan 11.

Infectious Diseases Department, Genentech Inc., South San Francisco, California, 94080, USA.

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http://www.nature.com/articles/s41598-017-18868-9
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http://dx.doi.org/10.1038/s41598-017-18868-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765126PMC
January 2018

type I signal peptidase: essential or not essential, that's the question.

Microb Cell 2017 Mar 17;4(4):108-111. Epub 2017 Mar 17.

Department of Infectious Diseases, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.15698/mic2017.04.566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376350PMC
March 2017

Antibody-Antibiotic Conjugates: A Novel Therapeutic Platform against Bacterial Infections.

Trends Mol Med 2017 02 23;23(2):135-149. Epub 2017 Jan 23.

Department of Infectious Diseases, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714914163019
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http://dx.doi.org/10.1016/j.molmed.2016.12.008DOI Listing
February 2017

Human Monoclonal Antibody 81.39a Effectively Neutralizes Emerging Influenza A Viruses of Group 1 and 2 Hemagglutinins.

J Virol 2016 Dec 14;90(23):10446-10458. Epub 2016 Nov 14.

Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

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http://dx.doi.org/10.1128/JVI.01284-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110155PMC
December 2016

Orthosiphon stamineus protects Caenorhabditis elegans against Staphylococcus aureus infection through immunomodulation.

Biol Open 2014 Jun 27;3(7):644-55. Epub 2014 Jun 27.

School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, 43600 UKM Bangi, Selangor, Malaysia

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http://dx.doi.org/10.1242/bio.20148334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154301PMC
June 2014

Discovery of potential anti-infectives against Staphylococcus aureus using a Caenorhabditis elegans infection model.

BMC Complement Altern Med 2014 Jan 6;14. Epub 2014 Jan 6.

School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.

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http://dx.doi.org/10.1186/1472-6882-14-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893568PMC
January 2014

Burkholderia pseudomallei suppresses Caenorhabditis elegans immunity by specific degradation of a GATA transcription factor.

Proc Natl Acad Sci U S A 2013 Sep 26;110(37):15067-72. Epub 2013 Aug 26.

School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.

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http://dx.doi.org/10.1073/pnas.1311725110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773767PMC
September 2013

Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus (QTL) for social behavior in Caenorhabditis elegans.

PLoS Genet 2012 20;8(12):e1003157. Epub 2012 Dec 20.

Howard Hughes Medical Institute, Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior, The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527333PMC
May 2013

Modulation of Caenorhabditis elegans infection sensitivity by the LIN-7 cell junction protein.

Cell Microbiol 2012 Oct 21;14(10):1584-99. Epub 2012 Jun 21.

Genome Institute of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1111/j.1462-5822.2012.01824.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470699PMC
October 2012

Transforming the untransformable: application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis.

mBio 2012 20;3(2). Epub 2012 Mar 20.

Moyne Institute of Preventive Medicine, Department of Microbiology, School of Genetics and Microbiology, Trinity College Dublin, Dublin, Ireland.

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http://mbio.asm.org/cgi/doi/10.1128/mBio.00277-11
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http://dx.doi.org/10.1128/mBio.00277-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312211PMC
June 2012

The two-component sensor kinase KdpD is required for Salmonella typhimurium colonization of Caenorhabditis elegans and survival in macrophages.

Cell Microbiol 2011 Oct 24;13(10):1618-37. Epub 2011 Aug 24.

Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2011.01645.xDOI Listing
October 2011

A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in Caenorhabditis elegans.

PLoS Genet 2011 Sep 29;7(9):e1002299. Epub 2011 Sep 29.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183084PMC
September 2011

Innate immunity: unfolding the neuro-immuno connections.

Authors:
Man-Wah Tan

Curr Biol 2011 Jun;21(12):R474-6

Department of Microbial Pathogenesis, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.cub.2011.05.010DOI Listing
June 2011

Genetic and molecular analysis of nematode-microbe interactions.

Cell Microbiol 2011 Apr 30;13(4):497-507. Epub 2011 Jan 30.

Department of Genetics and Microbiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2011.01570.xDOI Listing
April 2011

Complete killing of Caenorhabditis elegans by Burkholderia pseudomallei is dependent on prolonged direct association with the viable pathogen.

PLoS One 2011 Mar 7;6(3):e16707. Epub 2011 Mar 7.

School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM Bangi, Selangor, Malaysia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016707PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049773PMC
March 2011

It takes nerves to fight infections: insights on neuro-immune interactions from C. elegans.

Dis Model Mech 2010 Nov-Dec;3(11-12):721-31. Epub 2010 Sep 9.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 394305, USA.

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http://dx.doi.org/10.1242/dmm.003871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965399PMC
February 2011

Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans.

Proc Natl Acad Sci U S A 2010 Aug 20;107(31):13788-93. Epub 2010 Jul 20.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.0914715107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922217PMC
August 2010

The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans.

Aging Cell 2008 Dec 8;7(6):879-93. Epub 2008 Sep 8.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2008.00435.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630471PMC
December 2008

Neuroendocrine signals modulate the innate immunity of Caenorhabditis elegans through insulin signaling.

Nat Immunol 2008 Dec 14;9(12):1415-24. Epub 2008 Oct 14.

Department of Genetics, Department of Microbiology and Immunology, and Program in Immunology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ni.1672DOI Listing
December 2008

Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity.

PLoS Genet 2008 Nov 21;4(11):e1000273. Epub 2008 Nov 21.

Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581601PMC
November 2008

Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans.

PLoS Pathog 2008 Oct 17;4(10):e1000175. Epub 2008 Oct 17.

Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568960PMC
October 2008

Virulence of Leucobacter chromiireducens subsp. solipictus to Caenorhabditis elegans: characterization of a novel host-pathogen interaction.

Appl Environ Microbiol 2008 Jul 16;74(13):4185-98. Epub 2008 May 16.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1128/AEM.00381-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446502PMC
July 2008

Resistance to antimicrobial peptides contributes to persistence of Salmonella typhimurium in the C. elegans intestine.

Cell Microbiol 2008 Jun 21;10(6):1259-73. Epub 2008 Jan 21.

Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.

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http://doi.wiley.com/10.1111/j.1462-5822.2008.01124.x
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http://dx.doi.org/10.1111/j.1462-5822.2008.01124.xDOI Listing
June 2008

Genetic analysis of Caenorhabditis elegans innate immunity.

Methods Mol Biol 2008 ;415:429-42

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/978-1-59745-570-1_25DOI Listing
June 2008

Leucobacter chromiireducens subsp. solipictus subsp. nov., a pigmented bacterium isolated from the nematode Caenorhabditis elegans, and emended description of L. chromiireducens.

Int J Syst Evol Microbiol 2007 Dec;57(Pt 12):2770-6

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1099/ijs.0.64822-0DOI Listing
December 2007

Caenorhabditis elegans pgp-5 is involved in resistance to bacterial infection and heavy metal and its regulation requires TIR-1 and a p38 map kinase cascade.

Biochem Biophys Res Commun 2007 Nov 12;363(2):438-43. Epub 2007 Sep 12.

Department of Genetics and Department of Microbiology and Immunology, M337 Always Building, 300 Pasteur Drive, Stanford University School of Medicine, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1016/j.bbrc.2007.08.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276653PMC
November 2007

A conserved role for a GATA transcription factor in regulating epithelial innate immune responses.

Proc Natl Acad Sci U S A 2006 Sep 12;103(38):14086-91. Epub 2006 Sep 12.

Departments of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.0603424103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599916PMC
September 2006

Caenorhabditis elegans senses bacterial autoinducers.

Appl Environ Microbiol 2006 Jul;72(7):5135-7

Department of Cell Biology, Texas Tech University Health Sciences Center, Texas 79430, USA.

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http://aem.asm.org/cgi/doi/10.1128/AEM.00611-06
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http://dx.doi.org/10.1128/AEM.00611-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489312PMC
July 2006

Caenorhabditis elegans is a model host for Listeria monocytogenes.

Appl Environ Microbiol 2006 Feb;72(2):1700-1

Department of Veterinary Pathobiology, The Royal Veterinary and Agricultural University (KVL), Stigbøjlen 4, DK-1870 Frederiksberg C, Denmark.

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http://dx.doi.org/10.1128/AEM.72.2.1700-1701.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392976PMC
February 2006

Regulation of aging and innate immunity in C. elegans.

Aging Cell 2004 Aug;3(4):185-93

Department of Genetics, and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1111/j.1474-9728.2004.00108.xDOI Listing
August 2004

Characterization of mediators of microbial virulence and innate immunity using the Caenorhabditis elegans host-pathogen model.

Cell Microbiol 2003 Jul;5(7):435-44

Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford CA 94305, USA.

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http://dx.doi.org/10.1046/j.1462-5822.2003.00287.xDOI Listing
July 2003

Cross-species infections and their analysis.

Authors:
Man-Wah Tan

Annu Rev Microbiol 2002 30;56:539-65. Epub 2002 Jan 30.

Department of Genetics, Stanford University School of Medicine, California 94305, USA.

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http://dx.doi.org/10.1146/annurev.micro.56.012302.161110DOI Listing
January 2003

Identification of host and pathogen factors involved in virulence using Caenorhabditis elegans.

Authors:
Man-Wah Tan

Methods Enzymol 2002 ;358:13-28

Departments of Genetics, and Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)58078-2DOI Listing
January 2003