Malte Buchholz

Malte Buchholz

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Malte Buchholz

Malte Buchholz

Publications by authors named "Malte Buchholz"

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Stromal biology and therapy in pancreatic cancer: ready for clinical translation?

Gut 2019 01 3;68(1):159-171. Epub 2018 Sep 3.

Department of Gastroenterology, Endocrinology, Metabolism and Infectiology, University Hospital Marburg, UKGM, Philipps University Marburg, Marburg, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-316451
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http://dx.doi.org/10.1136/gutjnl-2018-316451DOI Listing
January 2019

DYRK1B regulates Hedgehog-induced microtubule acetylation.

Cell Mol Life Sci 2019 Jan 13;76(1):193-207. Epub 2018 Oct 13.

Institute of Molecular Biology and Tumor Research (IMT), Center for Tumor- and Immune Biology (ZTI), Philipps University, Hans-Meerwein-Str. 3, 35043, Marburg, Germany.

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http://link.springer.com/10.1007/s00018-018-2942-5
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http://dx.doi.org/10.1007/s00018-018-2942-5DOI Listing
January 2019

Inactivation of PRIM1 Function Sensitizes Cancer Cells to ATR and CHK1 Inhibitors.

Neoplasia 2018 11 23;20(11):1135-1143. Epub 2018 Sep 23.

Center for Tumor Biology and Immunology, Department of Gastroenterology, Endocrinology and Metabolism, University Hospital of Marburg, Philipps-University Marburg, Marburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14765586183038
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http://dx.doi.org/10.1016/j.neo.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154763PMC
November 2018

MicroRNA-30c as a novel diagnostic biomarker for primary and secondary B-cell lymphoma of the CNS.

J Neurooncol 2018 May 11;137(3):463-468. Epub 2018 Jan 11.

Department of Medicine, Ruhr-University of Bochum, Knappschaftskrankenhaus Bochum-Langendreer, Bochum, Germany.

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http://dx.doi.org/10.1007/s11060-018-2749-0DOI Listing
May 2018

The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators.

Oncotarget 2017 Sep 3;8(39):66215-66225. Epub 2017 Aug 3.

Department of Medicine, Division of Gastroenterology, Endocrinology and Metabolism, Philipps-University Marburg, Marburg, Germany.

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http://dx.doi.org/10.18632/oncotarget.19882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630405PMC
September 2017

Parkinson's disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus.

Parkinsonism Relat Disord 2016 12 28;33:115-121. Epub 2016 Sep 28.

Institute of Human Genetics, Justus-Liebig-University, Schlangenzahl 14, Gießen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.09.028DOI Listing
December 2016

microRNA profiling: increased expression of miR-147a and miR-518e in progressive supranuclear palsy (PSP).

Neurogenetics 2016 07 6;17(3):165-71. Epub 2016 Apr 6.

Institute of Human Genetics, Justus-Liebig-University, Gießen, Germany.

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http://dx.doi.org/10.1007/s10048-016-0480-6DOI Listing
July 2016

A multistep high-content screening approach to identify novel functionally relevant target genes in pancreatic cancer.

PLoS One 2015 7;10(4):e0122946. Epub 2015 Apr 7.

Clinic for Gastroenterology, Endocrinology, Metabolism and Infectiology, Philipps-University Marburg, Marburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388713PMC
March 2016

Kif20a inhibition reduces migration and invasion of pancreatic cancer cells.

J Surg Res 2015 Jul 30;197(1):91-100. Epub 2015 Mar 30.

Department of Surgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1016/j.jss.2015.03.070DOI Listing
July 2015

Aspirin prolongs survival and reduces the number of Foxp3+ regulatory T cells in a genetically engineered mouse model of pancreatic cancer.

Langenbecks Arch Surg 2013 Oct 30;398(7):989-96. Epub 2013 Aug 30.

Department of Surgery, Philipps University Marburg, Baldingerstrasse, D-35043, Marburg, Germany.

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http://dx.doi.org/10.1007/s00423-013-1105-2DOI Listing
October 2013

Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions.

Gut 2013 Jul 7;62(7):1034-43. Epub 2012 Jun 7.

Department of Gastroenterology, Endocrinology and Metabolism, Philipps University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1136/gutjnl-2012-302577DOI Listing
July 2013

Sorafenib inhibits tumor growth and improves survival in a transgenic mouse model of pancreatic islet cell tumors.

ScientificWorldJournal 2012 27;2012:529151. Epub 2012 Dec 27.

Department of Surgery, University Hospital Giessen and Marburg, Baldinger Strasse, 35043 Marburg, Germany.

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http://dx.doi.org/10.1100/2012/529151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543792PMC
July 2013

WNT5A-NFAT signaling mediates resistance to apoptosis in pancreatic cancer.

Neoplasia 2013 Jan;15(1):11-22

Department of Gastroenterology and Endocrinology, University Hospital, Philipps-University, D-35043 Marburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556935PMC
http://dx.doi.org/10.1593/neo.121312DOI Listing
January 2013

Immunoassay-based proteome profiling of 24 pancreatic cancer cell lines.

J Proteomics 2012 Jun 9;75(12):3747-59. Epub 2012 May 9.

Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 580, Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S18743919120026
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http://dx.doi.org/10.1016/j.jprot.2012.04.042DOI Listing
June 2012

Differentiation of multiple types of pancreatico-biliary tumors by molecular analysis of clinical specimens.

J Mol Med (Berl) 2012 Apr 26;90(4):457-64. Epub 2011 Nov 26.

Division of Gastroenterology, University Hospital, Philipps-Universitaet Marburg, Marburg, Germany.

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http://dx.doi.org/10.1007/s00109-011-0832-5DOI Listing
April 2012

Knock-down of Pdcd4 stimulates angiogenesis via up-regulation of angiopoietin-2.

Biochim Biophys Acta 2012 Apr 24;1823(4):789-99. Epub 2012 Jan 24.

Department of Gastroenterology, University of Marburg, Baldingerstrasse, Marburg, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2012.01.006DOI Listing
April 2012

Epithelial-mesenchymal transition is a critical step in tumorgenesis of pancreatic neuroendocrine tumors.

Cancers (Basel) 2012 Mar 8;4(1):281-94. Epub 2012 Mar 8.

Department of Surgery, Philipps University Marburg, Baldingerstraße, Marburg D-35043, Germany.

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http://dx.doi.org/10.3390/cancers4010281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712679PMC
March 2012

Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells.

PLoS One 2011 16;6(6):e20859. Epub 2011 Jun 16.

Department of Gastroenterology, Endocrinology and Metabolism, Philipps-University of Marburg, Marburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020859PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116838PMC
November 2011

TimeLapseAnalyzer: multi-target analysis for live-cell imaging and time-lapse microscopy.

Comput Methods Programs Biomed 2011 Nov 25;104(2):227-34. Epub 2011 Jun 25.

Department of Gastroenterology and Endocrinology, University Hospital of Marburg, Germany.

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http://dx.doi.org/10.1016/j.cmpb.2011.06.002DOI Listing
November 2011

Stromal biology and therapy in pancreatic cancer.

Gut 2011 Jun 21;60(6):861-8. Epub 2010 Oct 21.

Li Ka Shing Centre, Cambridge Research Institute, Cancer Research UK, Cambridge, UK.

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http://gut.bmj.com/cgi/doi/10.1136/gut.2010.226092
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http://dx.doi.org/10.1136/gut.2010.226092DOI Listing
June 2011

Screening technologies for target identification in pancreatic cancer.

Cancers (Basel) 2010 Dec 29;3(1):79-90. Epub 2010 Dec 29.

Department of Gastroenterology and Endocrinology, University Hospital, Philipps-University Marburg, Baldinger Strasse, D-35043 Marburg, Germany.

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http://dx.doi.org/10.3390/cancers3010079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756350PMC
December 2010

Microarray analysis reveals differential expression of benign and malignant pheochromocytoma.

Endocr Relat Cancer 2010 Sep 28;17(3):743-56. Epub 2010 Jul 28.

Department of Surgery, Philipps-Universität Marburg, Baldingerstrasse, D-35043 Marburg, Germany.

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http://dx.doi.org/10.1677/ERC-09-0118DOI Listing
September 2010

Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system.

BMC Cell Biol 2010 Apr 8;11:24. Epub 2010 Apr 8.

Research group of Bioinformatics and Systems Biology, Institute of Neural Information Processing, Ulm University, Albert-Einstein-Allee 11, D-89081 Ulm, Germany.

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http://dx.doi.org/10.1186/1471-2121-11-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858025PMC
April 2010

Molecular changes in pancreatic cancer.

Expert Rev Anticancer Ther 2009 Oct;9(10):1487-97

Klinik f. Innere Medizin, SP Gastroenterologie, Universitätsklinikum Marburg, Baldingerstrasse 35043 Marburg, Germany.

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http://dx.doi.org/10.1586/era.09.107DOI Listing
October 2009

Differential diagnosis of pancreatic tumors by molecular analysis of clinical specimens.

Pancreatology 2008 26;8(6):551-7. Epub 2008 Sep 26.

Division of Gastroenterology, University Hospital, Philipps-Universität Marburg, Marburg, Germany.

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http://dx.doi.org/10.1159/000159213DOI Listing
December 2008

Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors.

Pancreatology 2007 14;7(4):380-5. Epub 2007 Aug 14.

Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1159/000107400DOI Listing
November 2007

Snail and Sonic Hedgehog activation in neuroendocrine tumors of the ileum.

Endocr Relat Cancer 2007 Sep;14(3):865-74

Department of Pathology, John Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1677/ERC-07-0108DOI Listing
September 2007

An emerging role for Ca2+/calcineurin/NFAT signaling in cancerogenesis.

Cell Cycle 2007 Jan 27;6(1):16-9. Epub 2007 Jan 27.

Department of Gastroenterology, University of Marburg, Marburg, Hessen, Germany.

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http://dx.doi.org/10.4161/cc.6.1.3650DOI Listing
January 2007

Smad-Sp1 complexes mediate TGFbeta-induced early transcription of oncogenic Smad7 in pancreatic cancer cells.

Carcinogenesis 2006 Dec 19;27(12):2392-401. Epub 2006 May 19.

Department of Gastroenterology, University of Ulm, 89081 Ulm, Germany.

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http://dx.doi.org/10.1093/carcin/bgl078DOI Listing
December 2006

Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway.

EMBO J 2006 Aug 27;25(15):3714-24. Epub 2006 Jul 27.

Translational Genome Research Group, Department of Internal Medicine I, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7601246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538549PMC
August 2006

Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein.

J Mol Neurosci 2005 ;27(3):347-54

Zentrum für Neuropathologie und Prionforschung (ZNP), Ludwig-Maximilians-Universität München, München, Germany.

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http://dx.doi.org/10.1385/JMN:27:3:347DOI Listing
February 2006

Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions.

Oncogene 2005 Oct;24(44):6626-36

Department of Internal Medicine I, University Hospital of Ulm, Germany.

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http://dx.doi.org/10.1038/sj.onc.1208804DOI Listing
October 2005

Generalized Venn diagrams: a new method of visualizing complex genetic set relations.

Bioinformatics 2005 Apr 30;21(8):1592-5. Epub 2004 Nov 30.

Neuroinformatics, University of Ulm, 89069 Ulm, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bti169DOI Listing
April 2005

Identification of a Novel Transmembrane Protein (UKW): Association with Invasive Status of Mammary Carcinoma Cell Lines and Expression in Pancreatic Carcinoma.

Cancer Genomics Proteomics 2004 Jul-Aug;1(4):263-274. Epub 2004 Jul 1.

Roche Diagnostics GmbH, Pharma Research, 82377 Penzberg.

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July 2004

Application of DNA array analyses in the management of gastrointestinal cancer patients.

Dig Dis 2003 ;21(4):309-14

Department of Internal Medicine I, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1159/000075353DOI Listing
May 2004

LKW, a Putative Dual-specificity Kinase which is Down-regulated in Several Invasive Systems.

Cancer Genomics Proteomics 2004 Mar-Apr;1(2):177-188. Epub 2004 Mar 1.

Roche Diagnostics GmbH, Pharma Research, 82377 Penzberg.

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March 2004

Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer.

Cancer Res 2003 Oct;63(19):6265-71

Department of Internal Medicine I, University Hospital, University of Ulm, Robert-Koch-Strasse 8, 89081 Ulm, Germany.

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October 2003

SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo.

Cancer Res 2003 Aug;63(16):4945-51

Department of Internal Medicine I, University Medical Center, University of Ulm, 89081 Ulm, Germany.

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August 2003