Malik Alawi

Malik Alawi

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Malik Alawi

Malik Alawi

Publications by authors named "Malik Alawi"

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DAMIAN: an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples.

Sci Rep 2019 Nov 14;9(1):16841. Epub 2019 Nov 14.

Heinrich-Pette-Institute (HPI), Leibniz Institute for Experimental Virology, Research Group Virus Genomics, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41598-019-52881-4DOI Listing
November 2019

Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL.

Blood Cancer J 2019 Nov 29;9(12):96. Epub 2019 Nov 29.

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41408-019-0257-xDOI Listing
November 2019

De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.

Nat Biotechnol 2019 10 19;37(10):1137-1144. Epub 2019 Aug 19.

Department of Surgery, Division of Cardiothoracic Surgery, Transplant and Stem Cell Immunobiology Lab, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41587-019-0227-7DOI Listing
October 2019

Extremophilic nitrite-oxidizing Chloroflexi from Yellowstone hot springs.

ISME J 2019 Oct 17. Epub 2019 Oct 17.

Department of Microbiology and Biotechnology, Universität Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41396-019-0530-9DOI Listing
October 2019

Alternative interaction sites in the influenza A virus nucleoprotein mediate viral escape from the importin-α7 mediated nuclear import pathway.

FEBS J 2019 Sep 25;286(17):3374-3388. Epub 2019 May 25.

Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.

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http://dx.doi.org/10.1111/febs.14868DOI Listing
September 2019

T-lymphocyte-specific knockout of IKK-2 or NEMO induces T17 cells in an experimental nephrotoxic nephritis mouse model.

FASEB J 2019 02 4;33(2):2359-2371. Epub 2018 Oct 4.

III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1096/fj.201800485RRDOI Listing
February 2019

TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease.

Nucleic Acids Res 2019 01;47(1):341-361

Neuronal Translational Control Research Group, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), Hamburg 20251, Germany.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326785PMC
January 2019

Elsahy-Waters syndrome is caused by biallelic mutations in CDH11.

Am J Med Genet A 2018 02 22;176(2):477-482. Epub 2017 Dec 22.

Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1002/ajmg.a.38568DOI Listing
February 2018

Long-term CD38 saturation by daratumumab interferes with diagnostic myeloma cell detection.

Haematologica 2017 09 18;102(9):e368-e370. Epub 2017 May 18.

Department of Oncology and Hematology, Hubertus Wald Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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http://dx.doi.org/10.3324/haematol.2017.169235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685239PMC
September 2017

BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.

Nucleic Acids Res 2017 04;45(6):3130-3145

Department of General, Visceral and Pediatric Surgery, Göttingen Center for Molecular Biosciences, University Medical Center Göttingen, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1093/nar/gkw1276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389510PMC
April 2017

Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice.

Cell Host Microbe 2017 Mar;21(3):321-333

Research Group Viral Zoonosis and Adaptation, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, 20251 Hamburg, Germany; Centre for Structural and Cell Biology in Medicine, University of Lübeck, 23562 Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.02.020DOI Listing
March 2017

Versatility of Biofilm Matrix Molecules in Clinical Isolates and Importance of Polysaccharide Intercellular Adhesin Expression during High Shear Stress.

mSphere 2016 Sep-Oct;1(5). Epub 2016 Oct 5.

Department of Pathology and Microbiology, Center for Staphylococcal Research, University of Nebraska Medical Center, Omaha, Nebraska, USA.

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http://dx.doi.org/10.1128/mSphere.00165-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064449PMC
October 2016

Correlation of somatic mutations with outcome after FLAMSA-busulfan sequential conditioning and allogeneic stem cell transplantation in patients with myelodysplastic syndromes.

Eur J Haematol 2016 Sep 15;97(3):288-96. Epub 2016 Feb 15.

Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/ejh.12724DOI Listing
September 2016

Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles.

PLoS One 2016;11(9):e0163665. Epub 2016 Sep 29.

Research Department Cell and Gene Therapy, Clinic for Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042424PMC
September 2016

A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene.

Eur J Hum Genet 2016 08 16;24(8):1206-10. Epub 2015 Dec 16.

Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1038/ejhg.2015.261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970677PMC
August 2016

Rapid Capture Next-Generation Sequencing in Clinical Diagnostics of Kinase Pathway Aberrations in B-Cell Precursor ALL.

Pediatr Blood Cancer 2016 07 23;63(7):1283-6. Epub 2016 Mar 23.

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.25975DOI Listing
July 2016

Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis.

Am J Med Genet A 2016 07 4;170(7):1813-9. Epub 2016 May 4.

Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/ajmg.a.37682DOI Listing
July 2016

Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries.

Mol Ther 2016 06 28;24(6):1050-1061. Epub 2016 Mar 28.

Department of Oncology and Hematology, University Medical Center Hamburg-Eppendorf, Hubertus Wald Cancer Center, Hamburg, Germany; Current address: Department of Hematology and Oncology, Augsburg Medical Center, Augsburg, Germany. Electronic address:

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http://dx.doi.org/10.1038/mt.2016.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923327PMC
June 2016

A transplant "immunome" screening platform defines a targetable epitope fingerprint of multiple myeloma.

Blood 2016 06 31;127(25):3202-14. Epub 2016 Mar 31.

Department of Oncology and Hematology, Bone Marrow Transplantation with section Pneumology, Hubertus Wald Tumorzentrum/University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;

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http://dx.doi.org/10.1182/blood-2015-10-676536DOI Listing
June 2016

Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions.

Blood 2016 06 13;127(26):3369-81. Epub 2016 Apr 13.

Retroviral Pathogenesis, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany;

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http://dx.doi.org/10.1182/blood-2015-09-668129DOI Listing
June 2016

Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor.

Sci Rep 2016 06 13;6:27735. Epub 2016 Jun 13.

University of Veterinary Medicine, Department of Infectious Diseases, Institute of Virology, EU and OIE Reference Laboratory for Classical Swine Fever, Hannover, 30559, Germany.

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http://dx.doi.org/10.1038/srep27735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904412PMC
June 2016

Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis.

J Virol 2016 May 14;90(9):4626-4636. Epub 2016 Apr 14.

Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany

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http://dx.doi.org/10.1128/JVI.02987-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836318PMC
May 2016

Emergence of daptomycin non-susceptibility in colonizing vancomycin-resistant Enterococcus faecium isolates during daptomycin therapy.

Int J Med Microbiol 2015 Dec 12;305(8):902-9. Epub 2015 Sep 12.

Institut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2015.09.005DOI Listing
December 2015

Identification of a Novel Hepacivirus in Domestic Cattle from Germany.

J Virol 2015 Jul 29;89(14):7007-15. Epub 2015 Apr 29.

Institute of Virology, Department of Infectious Diseases, University of Veterinary Medicine Hannover, Hannover, Germany German Center for Infection Research, Partner Site Hannover-Braunschweig, Hannover, Germany

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http://dx.doi.org/10.1128/JVI.00534-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473572PMC
July 2015

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples.

J Clin Microbiol 2015 Jul 13;53(7):2238-50. Epub 2015 May 13.

German Center for Infection Research (DZIF), partner site Hamburg-Borstel-Lübeck, Germany Heinrich-Pette-Institute (HPI), Leibniz Institute for Experimental Virology, Research Group Virus Genomics, Hamburg, Germany.

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http://dx.doi.org/10.1128/JCM.02495-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473199PMC
July 2015

Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology.

J Mol Cell Cardiol 2015 Apr 26;81:1-9. Epub 2015 Jan 26.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.01.008DOI Listing
April 2015

SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts.

Cell Stem Cell 2015 Jan 20;16(1):33-8. Epub 2014 Nov 20.

TSI Laboratory, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, Germany; Cardiovascular Research Center Hamburg (CVRC) and DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, Martinistrasse 52, 20246 Hamburg, Germany; Stanford Cardiovascular Institute and Department of Cardiothoracic Surgery, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.11.003DOI Listing
January 2015

Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription.

Cell Rep 2014 Jul 10;8(2):460-9. Epub 2014 Jul 10.

Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; Institute for Molecular Oncology, University Medical Center Göttingen, 37077 Göttingen, Germany; Institute for Tumor Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747248PMC
July 2014

Next-generation sequencing of peripheral B-lineage cells pinpoints the circulating clonotypic cell pool in multiple myeloma.

Blood 2014 Jun 21;123(23):3618-21. Epub 2014 Apr 21.

University Medical Center Hamburg-Eppendorf, Hubertus Wald Tumorzentrum, University Cancer Center Hamburg, Department of Oncology, Hematology, Bone Marrow Transplantation with Section Pneumology, Hamburg, Germany;

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http://dx.doi.org/10.1182/blood-2014-02-556746DOI Listing
June 2014

Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer.

J Biol Chem 2013 Aug 29;288(32):22993-3008. Epub 2013 Jun 29.

Department of Tumor Biology, Leibniz-Institute for Experimental Virology, Virus Genomics, Hamburg, Germany.

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http://dx.doi.org/10.1074/jbc.M113.456293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743475PMC
August 2013

Runx1 is essential at two stages of early murine B-cell development.

Blood 2013 Jul 23;122(3):413-23. Epub 2013 May 23.

Molecular Pathology, Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, Martinistrasse 52, Hamburg, Germany.

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http://dx.doi.org/10.1182/blood-2013-01-480244DOI Listing
July 2013

CASSys: an integrated software-system for the interactive analysis of ChIP-seq data.

J Integr Bioinform 2011 Jun 21;8(2):155. Epub 2011 Jun 21.

Center for Bioinformatics, University of Hamburg, Bundesstraße 43, D-20146 Hamburg, Germany.

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http://journal.imbio.de/articles/pdf/jib-155.pdf
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http://biecoll.ub.uni-bielefeld.de/volltexte/2011/5170/
Publisher Site
http://dx.doi.org/10.2390/biecoll-jib-2011-155DOI Listing
June 2011