Publications by authors named "Malcolm Whitman"

29Publications

Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model.

J Heart Lung Transplant 2016 Apr 10;35(4):518-27. Epub 2015 Dec 10.

Latner Thoracic Surgery Research Laboratories, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2015.12.003DOI Listing
April 2016

Premature Termination Codons Are Recognized in the Nucleus in A Reading-Frame Dependent Manner.

Cell Discov 2015;1. Epub 2015 May 5.

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1038/celldisc.2015.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610414PMC
May 2015

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.

Sci Transl Med 2015 May;7(288):288ra77

Infectious Diseases Program, Broad Institute, Cambridge, MA 02142, USA. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa3575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675670PMC
May 2015

Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism.

Arthritis Res Ther 2015 May 15;17:126. Epub 2015 May 15.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard School of Medicine, Smith Research Building, 5th floor, 1 Jimmy Fund Way, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s13075-015-0647-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449585PMC
May 2015

Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2.

J Biol Chem 2012 May 5;287(22):18318-29. Epub 2012 Apr 5.

Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.M112.339424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365760PMC
May 2012

The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo.

Mech Dev 2010 Sep-Dec;127(9-12):485-95. Epub 2010 Aug 31.

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.mod.2010.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136463PMC
June 2011

Oxidative stress drives disulfide bond formation between basic helix-loop-helix transcription factors.

J Cell Biochem 2010 Feb;109(2):417-24

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1002/jcb.22415DOI Listing
February 2010

TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates.

Zoolog Sci 2008 Jul;25(7):706-13

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.

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http://www.bioone.org/doi/abs/10.2108/zsj.25.706
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http://dx.doi.org/10.2108/zsj.25.706DOI Listing
July 2008

TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.

Dev Biol 2008 Mar 3;315(1):203-16. Epub 2008 Jan 3.

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001216060701640
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http://dx.doi.org/10.1016/j.ydbio.2007.12.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292344PMC
March 2008

Identification of a novel pool of extracellular pro-myostatin in skeletal muscle.

J Biol Chem 2008 Mar 6;283(11):7027-35. Epub 2008 Jan 6.

Department of Developmental Biology, Harvard School of Dental Medicine, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M706678200DOI Listing
March 2008

A Serpin family gene, protease nexin-1 has an activity distinct from protease inhibition in early Xenopus embryos.

Mech Dev 2006 Jun 5;123(6):463-71. Epub 2006 May 5.

Department of Developmental Biology, Harvard School of Dental Medicine, Boston MA 02115, USA.

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http://dx.doi.org/10.1016/j.mod.2006.04.005DOI Listing
June 2006

Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo.

Dev Biol 2006 Jul 8;295(2):730-42. Epub 2006 May 8.

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ydbio.2006.03.050DOI Listing
July 2006

XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning.

Development 2006 Jan 8;133(2):237-50. Epub 2005 Dec 8.

Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1242/dev.02188DOI Listing
January 2006

Xnr2 and Xnr5 unprocessed proteins inhibit Wnt signaling upstream of dishevelled.

Dev Dyn 2005 Dec;234(4):900-10

Department of Life Sciences (Biology), Graduate School of Arts and Sciences, The University of Tokyo, Japan.

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http://doi.wiley.com/10.1002/dvdy.20574
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http://dx.doi.org/10.1002/dvdy.20574DOI Listing
December 2005

TGFbeta signaling at the summit.

Development 2005 Oct;132(19):4205-10

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.

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http://dx.doi.org/10.1242/dev.02023DOI Listing
October 2005

Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest induction.

Dev Biol 2005 Jan;277(2):425-42

Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.ydbio.2004.10.002DOI Listing
January 2005

New roles for FoxH1 in patterning the early embryo.

Development 2004 Oct;131(20):5065-78

Division of Developmental Biology, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1242/dev.01396DOI Listing
October 2004

Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction.

Development 2003 Dec 1;130(23):5589-99. Epub 2003 Oct 1.

Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1242/dev.00803DOI Listing
December 2003

p53 and TGF-beta in development: prelude to tumor suppression?

Cell 2003 May;113(3):275-6

Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00317-9DOI Listing
May 2003

Regulation of the Lim-1 gene is mediated through conserved FAST-1/FoxH1 sites in the first intron.

Dev Dyn 2002 Dec;225(4):448-56

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/dvdy.10176DOI Listing
December 2002

Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.

Genes Dev 2002 Nov;16(21):2749-54

Department of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1101/gad.1021802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC187472PMC
November 2002

Endogenous patterns of BMP signaling during early chick development.

Dev Biol 2002 Apr;244(1):44-65

Department of Cell Biology, Massachusetts General Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1006/dbio.2002.0579DOI Listing
April 2002