Malcolm R MacLeod

Malcolm R MacLeod

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Malcolm R MacLeod

Publications by authors named "Malcolm R MacLeod"

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Research Culture and Reproducibility.

Trends Cogn Sci 2019 Dec 28. Epub 2019 Dec 28.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.tics.2019.12.002DOI Listing
December 2019

Ischaemic stroke.

Nat Rev Dis Primers 2019 Oct 10;5(1):70. Epub 2019 Oct 10.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/s41572-019-0118-8DOI Listing
October 2019

Design of Meta-Analysis Studies.

Handb Exp Pharmacol 2019 Oct 17. Epub 2019 Oct 17.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1007/164_2019_289DOI Listing
October 2019

Compressive Pressure Versus Time in Cauda Equina Syndrome: A Systematic Review and Meta-Analysis of Experimental Studies.

Spine (Phila Pa 1976) 2019 Sep;44(17):1238-1247

Department of Clinical Neuroscience, Western General Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1097/BRS.0000000000003045DOI Listing
September 2019

A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus).

Res Integr Peer Rev 2019 12;4:12. Epub 2019 Jun 12.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1186/s41073-019-0069-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560728PMC
June 2019

The reproducibility opportunity.

Nat Hum Behav 2018 09;2(9):616-617

University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41562-018-0398-0DOI Listing
September 2018

NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons.

J Stroke Cerebrovasc Dis 2018 Aug 16;27(8):2158-2165. Epub 2018 Apr 16.

Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, Heidelberg, Victoria, Australia; University of Tasmania, School of Medicine, Faculty of Health, Hobart, Tasmania, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.03.015DOI Listing
August 2018

Effect size and statistical power in the rodent fear conditioning literature - A systematic review.

PLoS One 2018 26;13(4):e0196258. Epub 2018 Apr 26.

Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196258PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919667PMC
August 2018

A systematic review and meta-analysis of topoisomerase inhibition in pre-clinical glioma models.

Oncotarget 2018 Feb 29;9(13):11387-11401. Epub 2018 Jan 29.

Center for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.18632/oncotarget.24334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834287PMC
February 2018

Hypothermia revisited: Impact of ischaemic duration and between experiment variability.

J Cereb Blood Flow Metab 2017 Oct 13;37(10):3380-3390. Epub 2017 Jan 13.

1 Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, Heidelberg, Australia.

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http://dx.doi.org/10.1177/0271678X16688704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624387PMC
October 2017

Development of a psychological intervention for fatigue after stroke.

PLoS One 2017 17;12(8):e0183286. Epub 2017 Aug 17.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183286PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560529PMC
October 2017

Risk of bias reporting in the recent animal focal cerebral ischaemia literature.

Clin Sci (Lond) 2017 Oct 12;131(20):2525-2532. Epub 2017 Oct 12.

Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, Little France Crescent, Edinburgh, U.K.

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http://dx.doi.org/10.1042/CS20160722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869854PMC
October 2017

Standardized mean differences cause funnel plot distortion in publication bias assessments.

Elife 2017 09 8;6. Epub 2017 Sep 8.

Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE), Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.7554/eLife.24260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621838PMC
September 2017

The Efficacy of Trastuzumab in Animal Models of Breast Cancer: A Systematic Review and Meta-Analysis.

PLoS One 2016 27;11(7):e0158240. Epub 2016 Jul 27.

Centre for Clinical Brain Sciences, Chancellors Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158240PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963137PMC
July 2017

No publication without confirmation.

Nature 2017 02;542(7642):409-411

University of Edinburgh, UK.

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http://dx.doi.org/10.1038/542409aDOI Listing
February 2017

Improving our understanding of the modelling of psychotic disorders: A protocol for a systematic review and meta-analysis.

Evid Based Preclin Med 2016 Dec 17;3(2):e00022. Epub 2017 Mar 17.

Centre for Clinical Brain Sciences University of Edinburgh Edinburgh UK.

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http://dx.doi.org/10.1002/ebm2.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367269PMC
December 2016

Systematic Review and Meta-Analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke: an Update.

Transl Stroke Res 2016 10 15;7(5):395-406. Epub 2016 Aug 15.

Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1007/s12975-016-0489-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014900PMC
October 2016

Protocol for a Systematic Review of Effect Sizes and Statistical Power in the Rodent Fear Conditioning Literature.

Evid Based Preclin Med 2016 Jul;3(1)

Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1002/ebm2.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828109PMC
July 2016

Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis.

PLoS Biol 2016 05 31;14(5):e1002468. Epub 2016 May 31.

Department of Neurology and Experimental Neurology, Charité Campus Mitte, Clinical and Experimental Spinal Cord Injury Research Laboratory (Neuroparaplegiology), Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1371/journal.pbio.1002468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886956PMC
May 2016

Cardiac Stem Cell Treatment in Myocardial Infarction: A Systematic Review and Meta-Analysis of Preclinical Studies.

Circ Res 2016 Apr 17;118(8):1223-32. Epub 2016 Feb 17.

From the Department of Cardiology, Experimental Cardiology Laboratory, University Medical Center Utrecht, Utrecht, The Netherlands (P.P.Z., A.M.D.V., S.J.J.o.L., G.P.J.v.H., J.W.B., P.A.D., S.A.J.C., J.P.G.S.); Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands (A.M.D.V., M.-J.G.); Department of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom (G.L.C., E.S.S., M.R.M.); Department of Nephrology & Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands (H.G.); ICIN, Netherlands Heart Institute, Utrecht, The Netherlands (P.A.D., S.A.J.C., J.P.G.S.); and UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, Utrecht, The Netherlands (P.A.D., S.A.J.C., J.P.G.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307676DOI Listing
April 2016

Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models.

Cardiovasc Res 2016 Feb 20;109(2):240-8. Epub 2015 Oct 20.

Experimental Cardiology Laboratory, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584CX, The Netherlands Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvv239DOI Listing
February 2016

Risk of Bias in Reports of In Vivo Research: A Focus for Improvement.

PLoS Biol 2015 Oct 13;13(10):e1002273. Epub 2015 Oct 13.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom; Statistics and Informatics Platform, Florey Institute of Neuroscience and Mental Health, Melbourne, Australia.

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http://dx.doi.org/10.1371/journal.pbio.1002273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603955PMC
October 2015

Interventions for post-stroke fatigue.

Cochrane Database Syst Rev 2015 Jul 2(7):CD007030. Epub 2015 Jul 2.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/14651858.CD007030.pub3DOI Listing
July 2015

Magnetic resonance imaging in experimental stroke and comparison with histology: systematic review and meta-analysis.

Stroke 2015 Mar 5;46(3):843-51. Epub 2015 Feb 5.

From the Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.114.007560DOI Listing
March 2015

Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis.

Pain 2014 Dec 23;155(12):2461-70. Epub 2014 Sep 23.

Cancer Research UK, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.pain.2014.09.020DOI Listing
December 2014

Efficacy of antidepressants in animal models of ischemic stroke: a systematic review and meta-analysis.

Stroke 2014 Oct 2;45(10):3055-63. Epub 2014 Sep 2.

From The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia (S.K.M., E.S.S., D.W.H.); and Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom (C.I., G.E.M., E.S.S., G.L.C., K.E.E., M.R.M).

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http://dx.doi.org/10.1161/STROKEAHA.114.006304DOI Listing
October 2014

Hypothermia protects human neurons.

Int J Stroke 2014 Jul 3;9(5):544-52. Epub 2014 Jan 3.

Florey Institute of Neuroscience and Mental Health, Heidelberg, Vic, Australia; Department of Medicine, University of Melbourne, Heidelberg, Vic, Australia.

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http://dx.doi.org/10.1111/ijs.12224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235397PMC
July 2014

Using animal models to understand cancer pain in humans.

Curr Pain Headache Rep 2014 Jun;18(6):423

Department of Clinical Neurosciences, Chancellor's Building, University of Edinburgh, Edinburgh, UK,

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http://dx.doi.org/10.1007/s11916-014-0423-6DOI Listing
June 2014

Preclinical research: Design animal studies better.

Nature 2014 Jun;510(7503):35

1] University of Edinburgh, UK. [2].

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http://dx.doi.org/10.1038/510035aDOI Listing
June 2014

Systematic reviews and meta-analysis of preclinical studies: why perform them and how to appraise them critically.

J Cereb Blood Flow Metab 2014 May 19;34(5):737-42. Epub 2014 Feb 19.

Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/jcbfm.2014.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013765PMC
May 2014

End-of-life decisions in patients with severe acute brain injury.

Lancet Neurol 2014 May 25;13(5):515-24. Epub 2014 Mar 25.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1016/S1474-4422(14)70030-4DOI Listing
May 2014

Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis.

Crit Care Med 2014 Feb;42(2):231-42

1Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands. 2Center for Clinical Brain Sciences, Department of Clinical Neurosciences, University of Edinburgh, Scotland, UK. 3Klinik für Neurologie und Neurogeriatrie, Klinikum Darmstadt, Darmstadt, Germany.

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http://dx.doi.org/10.1097/CCM.0b013e3182a276e8DOI Listing
February 2014

Systematic review and meta-analysis of interventions tested in animal models of lacunar stroke.

Stroke 2014 Feb 2;45(2):563-70. Epub 2014 Jan 2.

From the Department of Clinical Neurosciences, Western General Hospital, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.113.003128DOI Listing
February 2014

Bringing rigour to translational medicine.

Nat Rev Neurol 2014 Jan 19;10(1):37-43. Epub 2013 Nov 19.

Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1038/nrneurol.2013.232DOI Listing
January 2014

Effect and reporting bias of RhoA/ROCK-blockade intervention on locomotor recovery after spinal cord injury: a systematic review and meta-analysis.

JAMA Neurol 2014 Jan;71(1):91-9

Department of Neurology and Experimental Neurology, Charité Campus Mitte, Clinical and Experimental Spinal Cord Injury Research Laboratory (Neuroparaplegiology), Charité-Universitätsmedizin, Berlin, Germany7Spinal Cord Injury Center, Trauma Hospital Berli.

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http://dx.doi.org/10.1001/jamaneurol.2013.4684DOI Listing
January 2014

Biomedical research: increasing value, reducing waste.

Lancet 2014 Jan 8;383(9912):101-4. Epub 2014 Jan 8.

Centre for Research in Evidence-Based Practice, Bond University, Robina, Gold Coast, QLD, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736136232
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http://dx.doi.org/10.1016/S0140-6736(13)62329-6DOI Listing
January 2014

Increasing value and reducing waste in research design, conduct, and analysis.

Lancet 2014 Jan 8;383(9912):166-75. Epub 2014 Jan 8.

Department of Health Research and Policy, Stanford University, Stanford, CA, USA; Department of Statistics, School of Humanities and Sciences, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1016/S0140-6736(13)62227-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697939PMC
January 2014

Hypertension and experimental stroke therapies.

J Cereb Blood Flow Metab 2013 Aug 5;33(8):1141-7. Epub 2013 Jun 5.

Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1038/jcbfm.2013.88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734784PMC
August 2013

Animal models of bone cancer pain: systematic review and meta-analyses.

Pain 2013 Jun 7;154(6):917-26. Epub 2013 Mar 7.

Department of Clinical Neurosciences, Chancellors Building, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.pain.2013.02.033DOI Listing
June 2013

Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis.

Pain 2013 May 14;154(5):632-42. Epub 2012 Dec 14.

Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.pain.2012.12.002DOI Listing
May 2013

Evidence-based translational medicine.

Stroke 2013 May 4;44(5):1466-71. Epub 2013 Apr 4.

Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.113.000469DOI Listing
May 2013

Systematic review and stratified meta-analysis of the efficacy of RhoA and Rho kinase inhibitors in animal models of ischaemic stroke.

Syst Rev 2013 May 20;2:33. Epub 2013 May 20.

The Department of Clinical Neurosciences, Chancellors Building, University of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1186/2046-4053-2-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665471PMC
May 2013

The benefit of hypothermia in experimental ischemic stroke is not affected by pethidine.

Int J Stroke 2013 Apr 3;8(3):180-5. Epub 2012 Jul 3.

Centre for Clinical Brain Sciences, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1747-4949.2012.00834.xDOI Listing
April 2013

Transparency in the reporting of in vivo pre-clinical pain research: The relevance and implications of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines.

Scand J Pain 2013 Apr 1;4(2):58-62. Epub 2013 Apr 1.

Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh United Kingdom.

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http://dx.doi.org/10.1016/j.sjpain.2013.02.002DOI Listing
April 2013

Stem cell-based therapy for experimental stroke: a systematic review and meta-analysis.

Int J Stroke 2012 Oct 12;7(7):582-8. Epub 2012 Jun 12.

Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1747-4949.2012.00797.xDOI Listing
October 2012

Pharmacologic reduction of angiographic vasospasm in experimental subarachnoid hemorrhage: systematic review and meta-analysis.

J Cereb Blood Flow Metab 2012 Sep 25;32(9):1643-4. Epub 2012 Apr 25.

Department of Neuroscience, Centre for Clinical Brain Sciences, University of Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1038/jcbfm.2012.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434633PMC
September 2012

Translational research.

Int J Stroke 2012 Jul;7(5):367-8

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http://dx.doi.org/10.1111/j.1747-4949.2012.00817_2.xDOI Listing
July 2012

Improving the efficiency of the development of drugs for stroke.

Int J Stroke 2012 Jul;7(5):371-7

Florey Neuroscience Institutes, Melbourne Brain Centre, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1747-4949.2012.00805.xDOI Listing
July 2012

Evaluation of combination therapy in animal models of cerebral ischemia.

J Cereb Blood Flow Metab 2012 Apr 1;32(4):585-97. Epub 2012 Feb 1.

Florey Neuroscience Institutes, Melbourne Brain Centre, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1038/jcbfm.2011.203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318154PMC
April 2012

Preclinical studies of human disease: time to take methodological quality seriously.

J Mol Cell Cardiol 2011 Oct 29;51(4):449-50. Epub 2011 Apr 29.

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http://dx.doi.org/10.1016/j.yjmcc.2011.04.008DOI Listing
October 2011

Sodium and chloride channelopathies with myositis: coincidence or connection?

Muscle Nerve 2011 Aug 22;44(2):283-8. Epub 2011 Jun 22.

Medical Research Council Centre for Neuromuscular Disease, UCL, Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1002/mus.22120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136616PMC
August 2011

Not tonight, darling, I might get a headache.

Stroke 2011 Jul 12;42(7):1807-8. Epub 2011 May 12.

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http://dx.doi.org/10.1161/STROKEAHA.111.617787DOI Listing
July 2011

Dopamine agonists in animal models of Parkinson's disease: a systematic review and meta-analysis.

Parkinsonism Relat Disord 2011 Jun 4;17(5):313-20. Epub 2011 Mar 4.

Department of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Royal Infirmary of Edinburgh, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2011.02.010DOI Listing
June 2011

Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism.

J Cereb Blood Flow Metab 2011 Apr 15;31(4):1064-72. Epub 2010 Dec 15.

Department of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1038/jcbfm.2010.217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070978PMC
April 2011

Treatment of intracerebral hemorrhage in animal models: meta-analysis.

Ann Neurol 2011 Feb;69(2):389-99

Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1002/ana.22243DOI Listing
February 2011

Hypothermia for Stroke: call to action 2010.

Int J Stroke 2010 Dec;5(6):489-92

Department of Clinical Neurosciences, University of Edinburgh,Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1747-4949.2010.00520.xDOI Listing
December 2010

Improving the translational hit of experimental treatments in multiple sclerosis.

Mult Scler 2010 Sep 4;16(9):1044-55. Epub 2010 Aug 4.

Centre for Clinical Brain Sciences, Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK.

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http://dx.doi.org/10.1177/1352458510379612DOI Listing
September 2010

Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia.

J Cereb Blood Flow Metab 2010 Aug 19;30(8):1412-31. Epub 2010 May 19.

National Stroke Research Institute and University of Melbourne Department of Medicine, Austin Health, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/jcbfm.2010.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949237PMC
August 2010

Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials?

J Cereb Blood Flow Metab 2010 Jun 31;30(6):1079-93. Epub 2010 Mar 31.

Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/jcbfm.2010.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949207PMC
June 2010

A systematic review and meta-analysis of erythropoietin in experimental stroke.

J Cereb Blood Flow Metab 2010 May 30;30(5):961-8. Epub 2009 Dec 30.

Department of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/jcbfm.2009.267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949185PMC
May 2010

Can animal models of disease reliably inform human studies?

PLoS Med 2010 Mar 30;7(3):e1000245. Epub 2010 Mar 30.

Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1371/journal.pmed.1000245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846855PMC
March 2010

Publication bias in reports of animal stroke studies leads to major overstatement of efficacy.

PLoS Biol 2010 Mar 30;8(3):e1000344. Epub 2010 Mar 30.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1000344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846857PMC
March 2010

Systematic review and stratified meta-analysis of the efficacy of interleukin-1 receptor antagonist in animal models of stroke.

J Stroke Cerebrovasc Dis 2009 Jul-Aug;18(4):269-76

Clinical Neurosciences, University of Edinburgh, Scotland, United Kingdom.

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September 2009

Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice.

Br J Pharmacol 2009 Aug 23;157(7):1154-6. Epub 2009 Jun 23.

Department of Neurology, Charite University Medicine, Berlin, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743833PMC
August 2009

Injury-induced mineralocorticoid receptor expression involves differential promoter usage: a novel role for the rat MRbeta variant.

Mol Cell Endocrinol 2009 Jun 28;305(1-2):56-62. Epub 2009 Feb 28.

Endocrinology Unit, Centre for Cardiovascular Science, University of Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.mce.2009.02.008DOI Listing
June 2009

Effect of hyperthermia and anoxia on glucocorticoid and mineralocorticoid receptor expression in neonatal rat hippocampus.

Neurosci Lett 2009 Jan 18;450(2):196-200. Epub 2008 Nov 18.

Department of Animal Physiology, Institute of General and Molecular Biology, N. Copernicus University, ul. Gagarina 9, 87-100 Toruń, Poland.

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January 2009

Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality.

Stroke 2008 Oct 17;39(10):2824-9. Epub 2008 Jul 17.

Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1161/STROKEAHA.108.515957DOI Listing
October 2008

A systematic review and meta-analysis of the efficacy of piracetam and piracetam-like compounds in experimental stroke.

Cerebrovasc Dis 2008 22;25(1-2):5-11. Epub 2007 Nov 22.

Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK.

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April 2008

Aortic arch atheroma.

Int J Stroke 2006 May;1(2):74-80

National Stroke Research Institute, Heidelbergh Heights, Victoria, Australia.

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May 2006