Malcolm J Moore

Malcolm J Moore

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Malcolm J Moore

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Detection of Relapse by Low-dose Computed Tomography During Surveillance in Stage I Testicular Germ Cell Tumours.

Eur Urol Oncol 2019 Jul 2;2(4):437-442. Epub 2018 Oct 2.

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.euo.2018.08.031DOI Listing
July 2019

Impact of Granulocyte-colony Stimulating Factor on Bleomycin-induced Pneumonitis in Chemotherapy-treated Germ Cell Tumors.

Clin Genitourin Cancer 2017 Sep 4. Epub 2017 Sep 4.

Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia; Department of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2017.08.012DOI Listing
September 2017

FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience.

Br J Cancer 2016 09 28;115(6):649-54. Epub 2016 Jul 28.

Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2M9, Canada.

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http://www.nature.com/articles/bjc2016222
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http://dx.doi.org/10.1038/bjc.2016.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023770PMC
September 2016

Survival Following Resection of Intra- and Extra-Hepatic Metastases from Colorectal Cancer: A Phase II Trial.

Ann Surg Oncol 2016 08 30;23(8):2644-51. Epub 2016 Mar 30.

Hepato-Pancreato-Biliary Surgical Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto General Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1245/s10434-016-5189-0DOI Listing
August 2016

Metformin for pancreatic cancer.

Lancet Oncol 2015 Jul 8;16(7):748-9. Epub 2015 Jun 8.

Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON M5G 2M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00029-7DOI Listing
July 2015

Multicenter Phase II Trial of Temsirolimus and Bevacizumab in Pancreatic Neuroendocrine Tumors.

J Clin Oncol 2015 May 8;33(14):1551-6. Epub 2014 Dec 8.

Timothy J. Hobday, Rui Qin, and Charles Erlichman, Mayo Clinic, Rochester, MN; Diane Reidy-Lagunes, Memorial Sloan Kettering Cancer Center, New York; Andreas Kaubisch, Montefiore Medical Center, Bronx, NY; Malcolm J. Moore, Princess Margaret Hospital, Toronto, Ontario, Canada; Jonathan Strosberg, H. Lee Moffitt Cancer Center, Tampa, FL; Manisha Shah, Ohio State University, Columbus, OH; Hedy Lee Kindler, University of Chicago, Chicago, IL; Heinz-Josef Lenz, University of Southern California, Los Angeles, CA; and Helen Chen, National Cancer Institute, Rockville, MD.

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http://dx.doi.org/10.1200/JCO.2014.56.2082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417726PMC
May 2015

Large retroperitoneal lymphadenopathy as a predictor of venous thromboembolism in patients with disseminated germ cell tumors treated with chemotherapy.

J Clin Oncol 2015 Feb 20;33(6):582-7. Epub 2015 Jan 20.

Amirrtha Srikanthan, Ben Tran, Michael A.S. Jewett, Robert J. Hamilton, Lynn Anson-Cartwright, Peter W.M. Chung, Padraig R. Warde, Martin O'Malley, Malcolm J. Moore, Eitan Amir, and Philippe L. Bedard, Princess Margaret Cancer Centre, University of Toronto, Toronto; Michel Beausoleil and Eric Winquist, Western University and London Health Sciences Centre, London, Ontario; Jeremy F.G. Sturgeon, McGill University, Montreal, Quebec, Canada; and Ben Tran, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://jco.ascopubs.org/content/early/2015/01/20/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.6537
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http://dx.doi.org/10.1200/JCO.2014.58.6537DOI Listing
February 2015

An open-label phase II study evaluating the safety and efficacy of ramucirumab combined with mFOLFOX-6 as first-line therapy for metastatic colorectal cancer.

Oncologist 2014 Apr 27;19(4):350-1. Epub 2014 Mar 27.

Hospital Universitario Virgen del Rocio, Instituto de Biomedicina de Sevilla (center affiliated with the Red Temática de Investigación Cooperativa en Cancer, Instituto Carlos III, Spanish Ministry of Science and Innovation), Sevilla, Spain;

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http://theoncologist.alphamedpress.org/content/19/4/350.full
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http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
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http://dx.doi.org/10.1634/theoncologist.2014-0028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983832PMC
April 2014

PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17.

Clin Cancer Res 2014 Feb 11;20(3):744-53. Epub 2013 Nov 11.

Authors' Affiliation: Flinders University, Flinders Centre for Innovation in Cancer; Department of Medical Oncology, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0606DOI Listing
February 2014

Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial.

J Natl Cancer Inst 2014 Jan 3;106(1):djt347. Epub 2013 Dec 3.

Affiliations of authors: Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK (WG, JPN, EG, TFC, PG, EC, CMH, CLR, FC, RJ); the Princess Margaret Hospital, Toronto, Canada (MJM); Manchester Academic Health Sciences Centre, Christie NHS Foundation Trust, School of Cancer and Enabling Sciences, University of Manchester, UK (JWV); Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK (DHP); Beatson West of Scotland Cancer Centre, Glasgow, UK (ACM); Glasgow Royal Infirmary, Glasgow, UK (RC); Hôpital Tenon, Université, Pierre et Marie Curie, Paris, France (FL); Austin Health, Melbourne, Australia (NCT); Prince of Wales Hospital and Clinical School University of New South Wales, New South Wales, Australia (DG); Nepean Cancer Centre and University of Sydney, Sydney, Australia (JS); Agia Olga Hospital, Athens, Greece (CD); Medical Oncology, Clatterbridge Centre for Oncology, Bebington, Merseyside, UK (DS); Department of Oncology, Akademiska Sjukhuset, Uppsala University, Uppsala, Sweden (BG); University Hospital, North Staffordshire, UK (MD); Freeman Hospital, Newcastle upon Tyne, UK (RMC); Service de Chirurgie Digestive et Viscérale, Hôpital Tenon, Paris, France (FL); Cross Cancer Institute and University of Alberta, Alberta, Canada (JRM, AGS); Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, UK (MRM); St James's University Hospital, Leeds, UK (AA); Department of Medicine A, University Medicine Greifswald, Greifswald, Germany (JM); Petz Aladar Hospital, Gyor, Hungary (AO); Departments of Surgery and Pathology and ARC-NET Research Center, University of Verona, Italy (AS, CB); Department of Surgery, University of Heidelberg, Heidelberg, Germany (MWB).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djt347DOI Listing
January 2014

Phase I study of axitinib (AG-013736) in combination with gemcitabine in patients with advanced pancreatic cancer.

Invest New Drugs 2012 Aug 14;30(4):1531-9. Epub 2011 Jun 14.

Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.

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http://link.springer.com/10.1007/s10637-011-9697-2
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http://dx.doi.org/10.1007/s10637-011-9697-2DOI Listing
August 2012

A phase II study of the halichondrin B analog eribulin mesylate in gemcitabine refractory advanced pancreatic cancer.

Invest New Drugs 2012 Jun 28;30(3):1203-7. Epub 2011 Apr 28.

University Health Network-Princess Margaret Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s10637-011-9673-xDOI Listing
June 2012

A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer.

Invest New Drugs 2012 Apr 18;30(2):779-86. Epub 2010 Dec 18.

Division of Medical Oncology and Hematology, Rm 5-708, Princess Margaret Hospital, 610 University Avenue, Toronto M5G2M9, Canada.

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http://dx.doi.org/10.1007/s10637-010-9611-3DOI Listing
April 2012

A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium.

Invest New Drugs 2011 Oct 27;29(5):1045-9. Epub 2010 Feb 27.

Princess Margaret Hospital, Phase II Consortium, 610 University Avenue, Suite 5-222, Toronto, Ontario M5G 2M9, Canada.

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http://link.springer.com/10.1007/s10637-010-9408-4
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http://dx.doi.org/10.1007/s10637-010-9408-4DOI Listing
October 2011

A phase II study of the antisense oligonucleotide GTI-2040 plus docetaxel and prednisone as first-line treatment in castration-resistant prostate cancer.

Cancer Chemother Pharmacol 2011 Apr 3;67(4):927-33. Epub 2010 Jul 3.

Princess Margaret Hospital, Phase II Consortium, University of Toronto, 610 University Avenue, Suite 5-222, Toronto, ON M5G 2M9, USA.

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http://dx.doi.org/10.1007/s00280-010-1389-7DOI Listing
April 2011

Longitudinal study of depressive symptoms in patients with metastatic gastrointestinal and lung cancer.

J Clin Oncol 2010 Jun 17;28(18):3084-9. Epub 2010 May 17.

Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.

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http://ascopubs.org/doi/10.1200/JCO.2009.26.9712
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http://dx.doi.org/10.1200/JCO.2009.26.9712DOI Listing
June 2010

Randomized phase II trials: inevitable or inadvisable?

J Clin Oncol 2010 May 20;28(15):2641-7. Epub 2010 Apr 20.

Princess Margaret Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1200/JCO.2009.26.3343DOI Listing
May 2010

Surgical oncology: Is PBD suitable for resectable pancreatic cancer?

Nat Rev Clin Oncol 2010 May;7(5):246-7

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http://dx.doi.org/10.1038/nrclinonc.2010.46DOI Listing
May 2010

Advanced pancreatic carcinoma: current treatment and future challenges.

Nat Rev Clin Oncol 2010 Mar 26;7(3):163-72. Epub 2010 Jan 26.

Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, ON M5G 2M9, Canada.

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http://www.nature.com/articles/nrclinonc.2009.236
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http://dx.doi.org/10.1038/nrclinonc.2009.236DOI Listing
March 2010

Choice of starting dose for molecularly targeted agents evaluated in first-in-human phase I cancer clinical trials.

J Clin Oncol 2010 Mar 1;28(8):1401-7. Epub 2010 Feb 1.

Division of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1200/JCO.2009.25.9606DOI Listing
March 2010

Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer.

J Clin Oncol 2009 May 23;27(13):2231-7. Epub 2009 Mar 23.

University Hospital Gasthuisberg/Leuven, Digestive Oncology Unit, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1200/JCO.2008.20.0238DOI Listing
May 2009

Alternate endpoints for screening phase II studies.

Clin Cancer Res 2009 Mar 10;15(6):1873-82. Epub 2009 Mar 10.

Princess Margaret Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2034DOI Listing
March 2009

Invasive pulmonary aspergillosis associated with marijuana use in a man with colorectal cancer.

J Clin Oncol 2008 May;26(13):2214-5

Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1200/JCO.2007.15.2777DOI Listing
May 2008

Sorafenib for metastatic renal cancer: the Princess Margaret experience.

Am J Clin Oncol 2008 Apr;31(2):182-7

Department of Medical Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/COC.0b013e3181574084DOI Listing
April 2008

A Phase 2 study of perifosine in advanced or metastatic breast cancer.

Breast Cancer Res Treat 2008 Mar 26;108(1):87-92. Epub 2007 Apr 26.

Medical Oncology, Princess Margaret Hospital/University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s10549-007-9584-xDOI Listing
March 2008

A case of small bowel obstruction due to intraluminal metastases from metastatic renal cell cancer.

Oncologist 2008 Feb;13(2):95-7

Department of Medicine, Princess Margaret Hospital, Toronto, Ontario, M5G 2M9, Canada.

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http://dx.doi.org/10.1634/theoncologist.2006-0214DOI Listing
February 2008

Neuroendocrine tumors of the gastrointestinal tract: a decade of experience at the Princess Margaret Hospital.

Am J Clin Oncol 2008 Feb;31(1):64-70

Department of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/COC.0b013e31807a2f49DOI Listing
February 2008

Erlotinib: success of a molecularly targeted agent for the treatment of advanced pancreatic cancer.

Future Oncol 2007 Jun;3(3):247-54

Princess Margaret Hospital, 5-700, 610 University Avenue Toronto, Ontario M5G 2M9, Canada.

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https://www.futuremedicine.com/doi/10.2217/14796694.3.3.247
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http://dx.doi.org/10.2217/14796694.3.3.247DOI Listing
June 2007

Interleukin-2 in the treatment of unresectable or metastatic renal cell cancer: Time to write the obituary?

Authors:
Malcolm J Moore

Can Urol Assoc J 2007 Mar;1(1):39

Professor of Medicine and Pharmacology, Princess Margaret Hospital, University of Toronto; Toronto, Ont.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2422916PMC
http://dx.doi.org/10.5489/cuaj.36DOI Listing
March 2007

Targeting metastatic prostate cancer: the search for innovative systemic therapies.

Oncology (Williston Park) 2006 Dec;20(14):1787-91; discussion 1791-6

Department of Medical Oncology and Hematology, Princess Margaret Hospital and University of Toronto Toronto, Ontario, Canada.

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December 2006

Novel targets in prostate cancer.

Expert Opin Ther Targets 2006 Oct;10(5):777-80

Princess Margaret Hospital and University of Toronto, Department of Medical Oncology and Hematology, 610 University Avenue Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1517/14728222.10.5.777 DOI Listing
October 2006

Consensus report of the international society of gastrointestinal oncology on therapeutic progress in advanced pancreatic cancer.

Cancer 2006 Aug;107(4):676-85

Department of Medicine/Clinical Pharmacology, New York University Cancer Institute, New York, New York, USA.

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http://doi.wiley.com/10.1002/cncr.22036
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http://dx.doi.org/10.1002/cncr.22036DOI Listing
August 2006

Population pharmacokinetics of troxacitabine, a novel dioxolane nucleoside analogue.

Clin Cancer Res 2006 Apr;12(7 Pt 1):2158-65

Department of Oncology, Johns Hopkins University and Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-2249DOI Listing
April 2006

A review of erlotinib and its clinical use.

Expert Opin Pharmacother 2006 Feb;7(2):177-93

Department of Medical Oncology and Hematology, Princess Margaret Hospital, University of Toronto, Toronto, M5G 2M9, Canada.

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http://dx.doi.org/10.1517/14656566.7.2.177DOI Listing
February 2006

Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer.

Clin Cancer Res 2006 Jan;12(1):144-51

Department of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada M5G 2M9.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-1571DOI Listing
January 2006

Determination of GTI-2040, a novel antisense oligonucleotide, in human plasma by using HPLC combined with solid phase and liquid-liquid extractions.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Dec 11;829(1-2):45-9. Epub 2005 Oct 11.

Department of Experimental Therapeutics, Ontario Cancer Institute, Ont. Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S157002320500676
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http://dx.doi.org/10.1016/j.jchromb.2005.09.036DOI Listing
December 2005

Brief communication: a new combination in the treatment of advanced pancreatic cancer.

Authors:
Malcolm J Moore

Semin Oncol 2005 Dec;32(6 Suppl 8):5-6

Department of Medical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.seminoncol.2005.07.017DOI Listing
December 2005

A Phase II study of oxaliplatin in urothelial cancer.

Urol Oncol 2005 May-Jun;23(3):150-4

Princess Margaret Hospital Phase II Consortium, London Regional Cancer Centre, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2004.11.008DOI Listing
September 2005

Epidermal growth factor receptor expression in anal canal carcinoma.

Am J Clin Pathol 2005 Jul;124(1):20-3

Department of Medical Oncology, Fraser Valley Cancer Centre, Surrey, Canada.

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http://dx.doi.org/10.1309/X4UADHVN317V2XMWDOI Listing
July 2005

Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial.

J Clin Oncol 2005 Apr;23(10):2332-8

Princess Margaret Hospital, 5-218, 610 University Ave, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2005.51.008DOI Listing
April 2005

A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix.

Eur J Cancer 2005 Mar 22;41(4):523-30. Epub 2005 Jan 22.

Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490401034
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http://dx.doi.org/10.1016/j.ejca.2004.12.013DOI Listing
March 2005

Simultaneous determination of OSI-774 and its major metabolite OSI-420 in human plasma by using HPLC with UV detection.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Jan;814(1):143-7

Department of Experimental Therapeutics, Ontario Cancer Institute, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jchromb.2004.10.016DOI Listing
January 2005

Outcome and toxicity of postoperative short course adjuvant radiation and chemotherapy following resection of adenocarcinoma of the rectum.

Acta Oncol 2004 ;43(6):567-70

Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital/Ontario Cancer Institute, University Health Network, Toronto Ontario, Canada.

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http://dx.doi.org/10.1080/02841860410014939DOI Listing
November 2004

Phase II study of activated charcoal to prevent irinotecan-induced diarrhea.

J Clin Oncol 2004 Nov;22(21):4410-7

Department of Medical Oncology and Hematology, Princess Margaret Hospital, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2004.11.125DOI Listing
November 2004

Counterpoint: Men should be treated for hormone refractory prostate cancer with systemic chemotherapy when they are symptomatic, and not before.

Authors:
Malcolm J Moore

Can J Urol 2003 Dec;10(6):2038-9

Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.

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December 2003

Sucralfate mouthwash for prevention and treatment of 5-fluorouracil-induced mucositis: a randomized, placebo-controlled trial.

Support Care Cancer 2003 Jan 23;11(1):41-7. Epub 2002 Jul 23.

Department of Medical Oncology, Princess Margaret Hospital, 610 University Ave, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1007/s00520-002-0378-8DOI Listing
January 2003

The role of systemic chemotherapy in the management of muscle-invasive bladder cancer.

Lancet Oncol 2002 Dec;3(12):738-47

Princess Margaret Hospital, Ontario, Toronto, Canada.

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December 2002

Pancreatic cancer: what the oncologist can offer for palliation.

Authors:
Malcolm J Moore

Can J Gastroenterol 2002 Feb;16(2):121-4

Department of Medicine, Princess Margaret Hospital, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1155/2002/380319DOI Listing
February 2002

Quality of life in advanced prostate cancer.

Authors:
Malcolm J. Moore

Can J Urol 1997 Jun;4(2 Supp 1):71-73

Departments of Medicine and Pharmacology, Princess Margaret Comprehensive Cancer Centre, University of Toronto, Toronto, Ontario.

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June 1997