Publications by authors named "Makoto M Taketo"

182Publications

Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.

Cell Stem Cell 2019 05 11;24(5):753-768.e6. Epub 2019 Apr 11.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Urology, University of Washington, Seattle, WA 98109, USA; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA. Electronic address:

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May 2019

Targeting β-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation.

Mol Neurobiol 2019 Jan 8;56(1):553-566. Epub 2018 May 8.

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Santander, Spain.

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January 2019

Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria.

Kidney Int 2018 06 28;93(6):1367-1383. Epub 2018 Mar 28.

Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China; The University of Hong Kong Shenzhen Institute of Research and Innovation, Hong Kong, China. Electronic address:

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June 2018

Wnt inhibition promotes vascular specification of embryonic cardiac progenitors.

Development 2018 01 8;145(1). Epub 2018 Jan 8.

Center for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA

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January 2018

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Dev Cell 2017 12 2;43(6):673-688.e5. Epub 2017 Nov 2.

Department of Developmental Neurobiology, Neurobiology and Brain Tumor Program, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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December 2017

Epithelial Wnt/βcatenin signalling is essential for epididymal coiling.

Dev Biol 2016 Apr 2;412(2):234-49. Epub 2016 Mar 2.

Gynaecology Oncology Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales 2308, Australia. Electronic address:

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April 2016

β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.

Genes Dev 2015 Jul 20;29(14):1493-506. Epub 2015 Jul 20.

Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;

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July 2015

Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.

Carcinogenesis 2015 Jul 4;36(7):719-29. Epub 2015 May 4.

Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto 606-8507, Japan,

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July 2015

A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.

PLoS One 2015 4;10(3):e0118561. Epub 2015 Mar 4.

Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan; TARA center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan.

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December 2015

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.

Proc Natl Acad Sci U S A 2015 Feb 20;112(5):E478-86. Epub 2015 Jan 20.

Department of Anatomy and Cell Biology and Roudebush Veterans Administration Medical Center and Division of Endocrinology, Department of Medicine, Indiana University School of Medicine;

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February 2015

SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis.

J Cell Biol 2014 Dec 1;207(5):657-71. Epub 2014 Dec 1.

Department of Cellular and Molecular Medicine, Orthopaedic and Rheumatologic Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195

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December 2014

CDC42 inhibition suppresses progression of incipient intestinal tumors.

Cancer Res 2014 Oct 11;74(19):5480-92. Epub 2014 Aug 11.

Department of Biological Sciences, Rutgers University, Newark, New Jersey. Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.

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October 2014

β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche.

Science 2014 Mar;343(6177):1353-6

Department of Genetics, Yale Stem Cell Center, Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06510, USA.

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March 2014

KLF5 regulates the integrity and oncogenicity of intestinal stem cells.

Cancer Res 2014 May 13;74(10):2882-91. Epub 2014 Mar 13.

Authors' Affiliations: Department of Molecular Pathology and Translational Research Unit, Tokyo Medical University; Cancer Genomics Project; Departments of Pathology, and Cardiovascular Medicine; Animal Resources, Graduate School of Medicine, University of Tokyo; Honeybee Science Research Center, Tamagawa University; Department of Gastroenterology, School of Medicine, Keio University, Tokyo; Department of Pharmacology, Graduate School of Medicine, Kyoto University, Kyoto; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology, Kobe; Jichi Medical University, Shimotsuke, Tochigi, Japan; and Hubrecht Institute and KNAW, Utrecht, the NetherlandsAuthors' Affiliations: Department of Molecular Pathology and Translational Research Unit, Tokyo Medical University; Cancer Genomics Project; Departments of Pathology, and Cardiovascular Medicine; Animal Resources, Graduate School of Medicine, University of Tokyo; Honeybee Science Research Center, Tamagawa University; Department of Gastroenterology, School of Medicine, Keio University, Tokyo; Department of Pharmacology, Graduate School of Medicine, Kyoto University, Kyoto; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology, Kobe; Jichi Medical University, Shimotsuke, Tochigi, Japan; and Hubrecht Institute and KNAW, Utrecht, the Netherlands

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May 2014