Publications by authors named "Majlinda Lako"

100Publications

Revisiting the role of factor H in age-related macular degeneration: insights from complement-mediated renal disease and rare genetic variants.

Surv Ophthalmol 2020 Nov 3. Epub 2020 Nov 3.

Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom; Sunderland Eye Infirmary, Sunderland, United Kingdom.

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http://dx.doi.org/10.1016/j.survophthal.2020.10.008DOI Listing
November 2020

Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review.

Ophthalmol Ther 2020 Sep 24. Epub 2020 Sep 24.

Biosciences Institute, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1007/s40123-020-00305-2DOI Listing
September 2020

Coculture techniques for modeling retinal development and disease, and enabling regenerative medicine.

Stem Cells Transl Med 2020 Dec 7;9(12):1531-1548. Epub 2020 Aug 7.

Sunderland Eye Infirmary, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK.

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http://dx.doi.org/10.1002/sctm.20-0201DOI Listing
December 2020

Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids.

PLoS One 2020 1;15(6):e0233860. Epub 2020 Jun 1.

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, England, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233860PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263587PMC
August 2020

AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31 iPSC-Derived RPE Cells.

Mol Ther Methods Clin Dev 2019 Dec 11;15:392-402. Epub 2019 Nov 11.

Department of Ophthalmology, Ocular Genomics Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.omtm.2019.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909184PMC
December 2019

Quantification of the morphological characteristics of hESC colonies.

Sci Rep 2019 11 26;9(1):17569. Epub 2019 Nov 26.

School of Mathematics, Statistics and Physics, Newcastle University, Newcastle upon Tyne, NE1 7RU, United Kingdom.

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http://dx.doi.org/10.1038/s41598-019-53719-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879623PMC
November 2019

Differentiation of Retinal Organoids from Human Pluripotent Stem Cells.

Curr Protoc Stem Cell Biol 2019 09;50(1):e95

Institute of Genetic Medicine, International Centre for Life, Newcastle University, Newcastle upon Tyne, United Kingdom.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cpsc.95
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http://dx.doi.org/10.1002/cpsc.95DOI Listing
September 2019

Endothelial Differentiation G Protein-Coupled Receptor 5 Plays an Important Role in Induction and Maintenance of Pluripotency.

Stem Cells 2019 03 7;37(3):318-331. Epub 2019 Feb 7.

International Centre for Life, Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom.

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http://doi.wiley.com/10.1002/stem.2954
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http://dx.doi.org/10.1002/stem.2954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446721PMC
March 2019

The Application of Biomaterials to Tissue Engineering Neural Retina and Retinal Pigment Epithelium.

Adv Healthc Mater 2018 12 2;7(23):e1800226. Epub 2018 Sep 2.

Newcastle University, Institute of Genetic Medicine, International Centre for Life, Central Parkway, Newcastle, NE1 3BZ, UK.

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http://dx.doi.org/10.1002/adhm.201800226DOI Listing
December 2018

Special Series: Transplantation of Stem Cells into the Eye.

Authors:
Majlinda Lako

Stem Cells 2018 10 22;36(10):1454-1456. Epub 2018 Aug 22.

Newcastle University, Institute of Genetic Medicine, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.2896DOI Listing
October 2018

Defining the optimal cryoprotectant and concentration for cryopreservation of limbal stem cells.

Cryobiology 2018 10 31;84:98-102. Epub 2018 Jul 31.

Division of Ophthalmology, University of Bristol, Bristol Eye Hospital, Lower Maudlin Street, Bristol BS1 2LX, UK.

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http://dx.doi.org/10.1016/j.cryobiol.2018.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167250PMC
October 2018

Cellular regeneration strategies for macular degeneration: past, present and future.

Eye (Lond) 2018 05 5;32(5):946-971. Epub 2018 Mar 5.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1038/s41433-018-0061-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944658PMC
May 2018

Outcomes of Penetrating Keratoplasty Following Autologous Cultivated Limbal Epithelial Stem Cell Transplantation.

Stem Cells 2018 06 23;36(6):925-931. Epub 2018 Mar 23.

Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.2803DOI Listing
June 2018

Hepatic differentiation of human iPSCs in different 3D models: A comparative study.

Int J Mol Med 2017 Dec 16;40(6):1759-1771. Epub 2017 Oct 16.

Bioreactor Group, Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, D-13353 Berlin, Germany.

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http://dx.doi.org/10.3892/ijmm.2017.3190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716452PMC
December 2017

Stem Cell-Based Therapy in Transplantation and Immune-Mediated Diseases.

Stem Cells Int 2017 6;2017:7379136. Epub 2017 Sep 6.

Faculty of Medical Sciences, Department of Genetics, University of Kragujevac, Kragujevac, Serbia.

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http://dx.doi.org/10.1155/2017/7379136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606049PMC
September 2017

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.

Toxicol In Vitro 2017 Dec 15;45(Pt 3):445-454. Epub 2017 Aug 15.

Division of Molecular and Computational toxicology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2017.07.023DOI Listing
December 2017

A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs.

Sci Rep 2017 02 3;7:41693. Epub 2017 Feb 3.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, NE1 3BZ, UK.

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http://dx.doi.org/10.1038/srep41693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290526PMC
February 2017

Concise Review: Getting to the Core of Inherited Bone Marrow Failures.

Stem Cells 2017 02 4;35(2):284-298. Epub 2016 Dec 4.

Institute of Genetic Medicine, Newcastle University, United Kingdom.

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http://dx.doi.org/10.1002/stem.2543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299470PMC
February 2017

3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development.

Acta Biomater 2017 02 5;49:329-343. Epub 2016 Nov 5.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle NE1 3BZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.11.016DOI Listing
February 2017

Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency.

Stem Cell Reports 2016 10 22;7(4):602-618. Epub 2016 Sep 22.

Josep Carreras Leukemia Research Institute, School of Medicine, University of Barcelona, Casanova 143, 08036 Barcelona, Spain; Department of Biomedicine, School of Medicine, University of Barcelona, 08036 Barcelona, Spain; Instituciò Catalana de Recerca i Estudis Avançats (ICREA), 08036 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063541PMC
October 2016

How to build a human.

Elife 2016 08 24;5. Epub 2016 Aug 24.

Institute of Genetic Medicine and North-East England Stem Cell Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.7554/eLife.19826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996647PMC
August 2016

Tissue engineering using pluripotent stem cells: multidisciplinary approaches to accelerate bench-to-bedside transition.

Regen Med 2016 09 3;11(6):495-8. Epub 2016 Aug 3.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.

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http://dx.doi.org/10.2217/rme-2016-0095DOI Listing
September 2016

Stem Cells, Inflammation, and Fibrosis.

Stem Cells Int 2016 24;2016:3891386. Epub 2016 Feb 24.

Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Science, University of Kragujevac, 69 Svetozara Markovica Street, 34000 Kragujevac, Serbia; Spebo Medical, 16 Norvezanska Street, 16000 Leskovac, Serbia.

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http://dx.doi.org/10.1155/2016/3891386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783542PMC
March 2016

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells.

Stem Cells 2016 05 4;34(5):1198-212. Epub 2016 Mar 4.

Institute of Genetic Medicine, International Centre for Life and Centre for Integrated Systems Biology of Ageing and Nutrition.

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http://dx.doi.org/10.1002/stem.2327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982072PMC
May 2016

Primordial Germ Cells: Current Knowledge and Perspectives.

Stem Cells Int 2016 9;2016:1741072. Epub 2015 Nov 9.

Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica Street, 34000 Kragujevac, Serbia ; Spebo Medical, Norvezanska 16, 16 000 Leskovac, Serbia.

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http://dx.doi.org/10.1155/2016/1741072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655300PMC
December 2015

Brief Report: Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells.

Stem Cells 2016 Jan 9;34(1):246-51. Epub 2015 Oct 9.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.2220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982107PMC
January 2016

Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa.

Lancet 2015 Feb;385 Suppl 1:S69

Scottish Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/S0140-6736(15)60384-1DOI Listing
February 2015

Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation.

Rejuvenation Res 2016 Feb;19(1):3-12

2 Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac , Kragujevac, Serbia .

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http://dx.doi.org/10.1089/rej.2015.1676DOI Listing
February 2016

Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells.

Stem Cells 2015 Sep 23;33(9):2643-51. Epub 2015 Jun 23.

Institute of Genetic Medicine, Newcastle University, The International Centre for Life, Central Parkway, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.2070DOI Listing
September 2015

Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population.

Methods Mol Biol 2016 ;1353:285-307

Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1007/7651_2015_205DOI Listing
August 2016

Engraftment's Holy Grail: is one signal enough?

Blood 2014 Nov;124(20):3035-6

NEWCASTLE UNIVERSITY.

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http://dx.doi.org/10.1182/blood-2014-09-600452DOI Listing
November 2014

Lab generated retina: realizing the dream.

Vis Neurosci 2014 Sep 22;31(4-5):317-32. Epub 2014 May 22.

Institute of Genetic Medicine,Newcastle University,Newcastle,United Kingdom.

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http://dx.doi.org/10.1017/S095252381400008XDOI Listing
September 2014

Stem cells as new agents for the treatment of infertility: current and future perspectives and challenges.

Biomed Res Int 2014 14;2014:507234. Epub 2014 Apr 14.

Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica Street, 34000 Kragujevac, Serbia ; Spebo Medical, 16 Norvezanska Street, 16000 Leskovac, Serbia.

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http://dx.doi.org/10.1155/2014/507234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009115PMC
December 2014

Concise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells?

Stem Cells 2014 Sep;32(9):2291-8

Institute of Genetic Medicine, Newcastle University, The International Centre for Life, Central Parkway, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.1720DOI Listing
September 2014

An induced pluripotent stem cell model of hypoplastic left heart syndrome (HLHS) reveals multiple expression and functional differences in HLHS-derived cardiac myocytes.

Stem Cells Transl Med 2014 Apr 3;3(4):416-23. Epub 2014 Mar 3.

Institute of Genetic Medicine and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom; Soochow University, Su Zhou, China; Princess Al Jawhara Center of Excellence in Research, King Abdulaziz University, Jeddah, Saudi Arabia; Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic; Institute of Cardiovascular Science, Manchester Academic Health Science Centre, CoreTechnology Facility, Manchester, United Kingdom; School of Biomedical Sciences, University of Durham, Durham, United Kingdom; Department of Human Genetics, University of Kragujevac, Kragujevac, Serbia.

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http://dx.doi.org/10.5966/sctm.2013-0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973710PMC
April 2014

Successful application of ex vivo expanded human autologous oral mucosal epithelium for the treatment of total bilateral limbal stem cell deficiency.

Stem Cells 2014 Aug;32(8):2135-46

Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom; Department of Ophthalmology, Royal Victoria Infirmary, Newcastle University, Newcastle, United Kingdom.

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http://dx.doi.org/10.1002/stem.1694DOI Listing
August 2014

The limbal epithelium of the eye--a review of limbal stem cell biology, disease and treatment.

Bioessays 2013 Mar 5;35(3):211-9. Epub 2012 Nov 5.

Institute of Genetic Medicine, Newcastle University, Newcastle, UK.

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http://doi.wiley.com/10.1002/bies.201200086
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http://dx.doi.org/10.1002/bies.201200086DOI Listing
March 2013

An investigation of donor and culture parameters which influence epithelial outgrowths from cultured human cadaveric limbal explants.

J Cell Physiol 2013 May;228(5):1025-30

Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/jcp.24249DOI Listing
May 2013

A putative role for the immunoproteasome in the maintenance of pluripotency in human embryonic stem cells.

Stem Cells 2012 Jul;30(7):1373-84

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://doi.wiley.com/10.1002/stem.1113
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http://dx.doi.org/10.1002/stem.1113DOI Listing
July 2012

SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells.

Mol Ther 2012 Jul 10;20(7):1443-53. Epub 2012 Apr 10.

Pfizer-Universidad de Granada-Junta de Andalucia Centre for Genomics and Oncological Research (GENyO), Granada, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163257
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http://dx.doi.org/10.1038/mt.2012.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392972PMC
July 2012

Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells.

Stem Cells 2012 Apr;30(4):673-86

Institute of Genetic Medicine, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1002/stem.1037DOI Listing
April 2012

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Authors:
Katherine Amps Peter W Andrews George Anyfantis Lyle Armstrong Stuart Avery Hossein Baharvand Julie Baker Duncan Baker Maria B Munoz Stephen Beil Nissim Benvenisty Dalit Ben-Yosef Juan-Carlos Biancotti Alexis Bosman Romulo Martin Brena Daniel Brison Gunilla Caisander María V Camarasa Jieming Chen Eric Chiao Young Min Choi Andre B H Choo Daniel Collins Alan Colman Jeremy M Crook George Q Daley Anne Dalton Paul A De Sousa Chris Denning Janet Downie Petr Dvorak Karen D Montgomery Anis Feki Angela Ford Victoria Fox Ana M Fraga Tzvia Frumkin Lin Ge Paul J Gokhale Tamar Golan-Lev Hamid Gourabi Michal Gropp Guangxiu Lu Ales Hampl Katie Harron Lyn Healy Wishva Herath Frida Holm Outi Hovatta Johan Hyllner Maneesha S Inamdar Astrid Kresentia Irwanto Tetsuya Ishii Marisa Jaconi Ying Jin Susan Kimber Sergey Kiselev Barbara B Knowles Oded Kopper Valeri Kukharenko Anver Kuliev Maria A Lagarkova Peter W Laird Majlinda Lako Andrew L Laslett Neta Lavon Dong Ryul Lee Jeoung Eun Lee Chunliang Li Linda S Lim Tenneille E Ludwig Yu Ma Edna Maltby Ileana Mateizel Yoav Mayshar Maria Mileikovsky Stephen L Minger Takamichi Miyazaki Shin Yong Moon Harry Moore Christine Mummery Andras Nagy Norio Nakatsuji Kavita Narwani Steve K W Oh Sun Kyung Oh Cia Olson Timo Otonkoski Fei Pan In-Hyun Park Steve Pells Martin F Pera Lygia V Pereira Ouyang Qi Grace Selva Raj Benjamin Reubinoff Alan Robins Paul Robson Janet Rossant Ghasem H Salekdeh Thomas C Schulz Karen Sermon Jameelah Sheik Mohamed Hui Shen Eric Sherrer Kuldip Sidhu Shirani Sivarajah Heli Skottman Claudia Spits Glyn N Stacey Raimund Strehl Nick Strelchenko Hirofumi Suemori Bowen Sun Riitta Suuronen Kazutoshi Takahashi Timo Tuuri Parvathy Venu Yuri Verlinsky Dorien Ward-van Oostwaard Daniel J Weisenberger Yue Wu Shinya Yamanaka Lorraine Young Qi Zhou

Nat Biotechnol 2011 Nov 27;29(12):1132-44. Epub 2011 Nov 27.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK.

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http://www.nature.com/articles/nbt.2051
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http://dx.doi.org/10.1038/nbt.2051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454460PMC
November 2011

Neural stem cells, a step closer to clinic?

Stem Cells 2011 Oct;29(10):1477-8

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http://dx.doi.org/10.1002/stem.729DOI Listing
October 2011

Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells.

Stem Cells 2011 Jul;29(7):1021-33

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.658DOI Listing
July 2011

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

Stem Cells 2011 Apr;29(4):651-9

Institute of Human Genetics, Newcastle University, International Centre for Life, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/stem.620DOI Listing
April 2011

13 years of cultured limbal epithelial cell therapy: a review of the outcomes.

J Cell Biochem 2011 Apr;112(4):993-1002

Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/jcb.23028DOI Listing
April 2011

Opposing putative roles for canonical and noncanonical NFκB signaling on the survival, proliferation, and differentiation potential of human embryonic stem cells.

Stem Cells 2010 Nov;28(11):1970-80

Institute of Human Genetics, International Centre for Life, Newcastle University, Newcastle Upon Tyne, United Kingdom.

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http://doi.wiley.com/10.1002/stem.528
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http://dx.doi.org/10.1002/stem.528DOI Listing
November 2010

Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury.

Stem Cell Res 2010 Nov 31;5(3):255-66. Epub 2010 Aug 31.

Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1016/j.scr.2010.08.004DOI Listing
November 2010

Law, ethics, religion, and clinical translation in the 21st century--a discussion with Andrew Webster.

Stem Cells 2010 Nov;28(11):1915-7

Institute of Human Genetics and NESCI, Newcastle University, International Centre for Life, Central Parkway, Newcastle NE1 3BZ, United Kingdom.

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http://dx.doi.org/10.1002/stem.519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003907PMC
November 2010

Retinoid supplementation of differentiating human neural progenitors and embryonic stem cells leads to enhanced neurogenesis in vitro.

J Neurosci Methods 2010 Nov 9;193(2):239-45. Epub 2010 Sep 9.

School of Biological and Biomedical Sciences, Durham University, Science Laboratories, South Road, Durham, UK.

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http://dx.doi.org/10.1016/j.jneumeth.2010.08.022DOI Listing
November 2010