Mahdad Noursadeghi

Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic.

Eur J Prev Cardiol 2021 Feb 21. Epub 2021 Feb 21.

Institute of Health Informatics, University College London, 222 Euston Road, London, UK, NW1 1DA.

February 2021

Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19.

Authors:

João B Augusto Katia Menacho Mervyn Andiapen Ruth Bowles Maudrian Burton Sophie Welch Anish N Bhuva Andreas Seraphim Corinna Pade George Joy Melanie Jensen Rhodri H Davies Gabriella Captur Marianna Fontana Hugh Montgomery Ben O'Brien Aroon D Hingorani Teresa Cutino-Moguel Áine McKnight Hakam Abbass Mashael Alfarih Zoe Alldis Georgina L Baca Alex Boulter Olivia V Bracken Natalie Bullock Nicola Champion Carmen Chan Xose Couto-Parada Keenan Dieobi-Anene Karen Feehan Gemma Figtree Melanie C Figtree Malcolm Finlay Nasim Forooghi Joseph M Gibbons Peter Griffiths Matt Hamblin Lee Howes Ivie Itua Meleri Jones Victor Jardim Vikas Kapil Wing-Yiu Jason Lee Vineela Mandadapu Celina Mfuko Oliver Mitchelmore Susana Palma Kush Patel Steffen E Petersen Brian Piniera Rosalind Raine Alicja Rapala Amy Richards Genine Sambile Jorge Couto de Sousa Michelle Sugimoto George D Thornton Jessica Artico Dan Zahedi Ruth Parker Mathew Robathan Lauren M Hickling Ntobeko Ntusi Amanda Semper Tim Brooks Jessica Jones Art Tucker Jessry Veerapen Mohit Vijayakumar Theresa Wodehouse Lucinda Wynne Thomas A Treibel Mahdad Noursadeghi Charlotte Manisty James C Moon

Wellcome Open Res 2020 12;5:179. Epub 2020 Oct 12.

Institute of Cardiovascular Science, University College London, London, UK.

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October 2020

Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study.

BMC Med 2021 01 21;19(1):23. Epub 2021 Jan 21.

Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London, SE5 8AF, UK.

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January 2021

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study.

Lancet Respir Med 2021 Jan 11. Epub 2021 Jan 11.

Division of Infection and Immunity, University College London, London, UK. Electronic address:

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January 2021

NIX-mediated mitophagy regulate metabolic reprogramming in phagocytic cells during mycobacterial infection.

Authors:

Ranjeet Singh Mahla Akhilesh Kumar Helena J Tutill Sreevidhya Tarakkad Krishnaji Bharathwaj Sathyamoorthy Mahdad Noursadeghi Judith Breuer Amit Kumar Pandey Himanshu Kumar

Tuberculosis (Edinb) 2021 Jan 30;126:102046. Epub 2020 Dec 30.

Laboratory of Immunology and Infectious Disease Biology, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal, India; Laboratory of Host Defense, WPI Immunology Frontier Research Centre, Osaka University, Osaka, Japan. Electronic address:

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January 2021

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.

Sci Immunol 2020 12;5(54)

Department of Infectious Disease, Imperial College London, London, UK.

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December 2020

Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19.

Authors:

Lucy C K Bell Cem Meydan Jacob Kim Jonathan Foox Daniel Butler Christopher E Mason Sagi D Shapira Mahdad Noursadeghi Gabriele Pollara

iScience 2021 Jan 7;24(1):101896. Epub 2020 Dec 7.

Division of Infection & Immunity, University College London, Cruciform Building, Gower Street, London WC1E 6BT, UK.

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January 2021

Transcriptional response modules characterise IL-1β and IL-6 activity in COVID-19.

Authors:

Lucy Ck Bell Cem Meydan Jacob Kim Jonathan Foox Daniel Butler Christopher E Mason Sagi D Shapira Mahdad Noursadeghi Gabriele Pollara

bioRxiv 2020 Dec 3. Epub 2020 Dec 3.

Division of Infection & Immunity, University College London, London, UK.

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December 2020

Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.

BMJ Open 2020 11 17;10(11):e043828. Epub 2020 Nov 17.

Institute of Health Informatics, University College London, London, UK.

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November 2020

Asymptomatic health-care worker screening during the COVID-19 pandemic - Authors' reply.

Authors:

Thomas A Treibel Charlotte Manisty Mervyn Andiapen Corinna Pade Melanie Jensen Marianna Fontana Xosé Couto-Parada Teresa Cutino-Moguel Mahdad Noursadeghi James C Moon

Lancet 2020 10;396(10260):1394-1395

Institute of Cardiovascular Science, University College London, London, UK; Department of Cardiology, St Bartholomew's Hospital, Barts Health NHS Trust, London EC1A 7BE, UK. Electronic address:

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October 2020

Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings.

Nat Med 2020 12 19;26(12):1941-1949. Epub 2020 Oct 19.

Institute for Global Health, University College London, London, UK.

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December 2020

Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: an observational cohort study.

Authors:

Rishi K Gupta Michael Marks Thomas H A Samuels Akish Luintel Tommy Rampling Humayra Chowdhury Matteo Quartagno Arjun Nair Marc Lipman Ibrahim Abubakar Maarten van Smeden Wai Keong Wong Bryan Williams Mahdad Noursadeghi

Eur Respir J 2020 12 24;56(6). Epub 2020 Dec 24.

University College London Hospitals NHS Trust, London, UK.

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December 2020

Correction to: Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study.

Authors:

Dayle Sampson Thomas D Yager Brian Fox Laura Shallcross Leo McHugh Therese Seldon Antony Rapisarda Roslyn A Hendriks Richard B Brandon Krupa Navalkar Nandi Simpson Sian Stafford Eliza Gil Cristina Venturini Evi Tsaliki Jennifer Roe Benjamin Chain Mahdad Noursadeghi

BMC Med 2020 Sep 12;18(1):293. Epub 2020 Sep 12.

Division of Infection and Immunity, University College London, London, UK.

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September 2020

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.

BMJ 2020 09 9;370:m3339. Epub 2020 Sep 9.

Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.

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September 2020

Clinical academic research in the time of Corona: A simulation study in England and a call for action.

Authors:

Amitava Banerjee Michail Katsoulis Alvina G Lai Laura Pasea Thomas A Treibel Charlotte Manisty Spiros Denaxas Giovanni Quarta Harry Hemingway João L Cavalcante Mahdad Noursadeghi James C Moon

PLoS One 2020 13;15(8):e0237298. Epub 2020 Aug 13.

Barts NHS Trust, London, United Kingdom.

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August 2020

Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study.

Authors:

Dayle Sampson Thomas D Yager Brian Fox Laura Shallcross Leo McHugh Therese Seldon Antony Rapisarda Roslyn A Hendriks Richard B Brandon Krupa Navalkar Nandi Simpson Sian Stafford Eliza Gil Cristina Venturini Evi Tsaliki Jennifer Roe Benjamin Chain Mahdad Noursadeghi

BMC Med 2020 07 21;18(1):185. Epub 2020 Jul 21.

Division of Infection and Immunity, University College London, London, UK.

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July 2020

Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.

Nat Med 2020 Jul;26(7):1148

Division of Infection and Immunity, University College London, London, UK.

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July 2020

Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study.

Authors:

Amitava Banerjee Laura Pasea Steve Harris Arturo Gonzalez-Izquierdo Ana Torralbo Laura Shallcross Mahdad Noursadeghi Deenan Pillay Neil Sebire Chris Holmes Christina Pagel Wai Keong Wong Claudia Langenberg Bryan Williams Spiros Denaxas Harry Hemingway

Lancet 2020 05 12;395(10238):1715-1725. Epub 2020 May 12.

Institute of Health Informatics, University College London, London, UK; Health Data Research UK, London, UK.

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May 2020

COVID-19: PCR screening of asymptomatic health-care workers at London hospital.

Authors:

Thomas A Treibel Charlotte Manisty Maudrian Burton Áine McKnight Jonathan Lambourne João B Augusto Xosé Couto-Parada Teresa Cutino-Moguel Mahdad Noursadeghi James C Moon

Lancet 2020 05 8;395(10237):1608-1610. Epub 2020 May 8.

Institute of Cardiovascular Science, University College London, London, UK; Department of Cardiology, St Bartholomew's Hospital, London, UK. Electronic address:

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May 2020

Blood transcriptional biomarkers for active pulmonary tuberculosis in a high-burden setting: a prospective, observational, diagnostic accuracy study.

Authors:

Carolin T Turner Rishi K Gupta Evdokia Tsaliki Jennifer K Roe Prasenjit Mondal Georgina R Nyawo Zaida Palmer Robert F Miller Byron Wp Reeve Grant Theron Mahdad Noursadeghi

Lancet Respir Med 2020 04 13;8(4):407-419. Epub 2020 Mar 13.

Division of Infection and Immunity, University College London, London, UK. Electronic address:

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April 2020

Viral infection triggers interferon-induced expulsion of live Cryptococcus neoformans by macrophages.

Authors:

Paula I Seoane Leanne M Taylor-Smith David Stirling Lucy C K Bell Mahdad Noursadeghi Dalan Bailey Robin C May

PLoS Pathog 2020 02 27;16(2):e1008240. Epub 2020 Feb 27.

Institute of Microbiology & Infection and School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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February 2020

Evaluation of QuantiFERON-TB Gold Plus for Predicting Incident Tuberculosis among Recent Contacts: A Prospective Cohort Study.

Authors:

Rishi K Gupta Heinke Kunst Marc Lipman Mahdad Noursadeghi Charlotte Jackson Jo Southern Ambreen Imran Stefan Lozewicz Ibrahim Abubakar

Ann Am Thorac Soc 2020 05;17(5):646-650

University College LondonLondon, United Kingdom.

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May 2020

Analysis tools to quantify dissemination of pathology in zebrafish larvae.

Authors:

David R Stirling Oniz Suleyman Eliza Gil Philip M Elks Vincenzo Torraca Mahdad Noursadeghi Gillian S Tomlinson

Sci Rep 2020 02 21;10(1):3149. Epub 2020 Feb 21.

Infection and Immunity, University College London, Cruciform Building, Gower Street, London, WC1E 6BT, United Kingdom.

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February 2020

Concise whole blood transcriptional signatures for incipient tuberculosis: a systematic review and patient-level pooled meta-analysis.

Authors:

Rishi K Gupta Carolin T Turner Cristina Venturini Hanif Esmail Molebogeng X Rangaka Andrew Copas Marc Lipman Ibrahim Abubakar Mahdad Noursadeghi

Lancet Respir Med 2020 04 17;8(4):395-406. Epub 2020 Jan 17.

Division of Infection & Immunity, University College London, London, UK. Electronic address:

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April 2020

Quantitative IFN-γ Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis. A Prospective Cohort Study.

Authors:

Rishi K Gupta Marc Lipman Charlotte Jackson Alice J Sitch Jo Southern Francis Drobniewski Jonathan J Deeks Chuen-Yan Tsou Chris Griffiths Jennifer Davidson Colin Campbell Oliver Stirrup Mahdad Noursadeghi Heinke Kunst Pranab Haldar Ajit Lalvani Ibrahim Abubakar

Am J Respir Crit Care Med 2020 04;201(8):984-991

Institute for Global Health.

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April 2020

Assessing the Impact of Sample Heterogeneity on Transcriptome Analysis of Human Diseases Using MDP Webtool.

Authors:

André N A Gonçalves Melissa Lever Pedro S T Russo Bruno Gomes-Correia Alysson H Urbanski Gabriele Pollara Mahdad Noursadeghi Vinicius Maracaja-Coutinho Helder I Nakaya

Front Genet 2019 24;10:971. Epub 2019 Oct 24.

Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.

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October 2019

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.

Nat Med 2019 10 7;25(10):1549-1559. Epub 2019 Oct 7.

Division of Infection and Immunity, University College London, London, UK.

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October 2019

Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae.

Authors:

Jimstan Periselneris Giuseppe Ercoli Tracey Pollard Suneeta Chimalapati Emilie Camberlein Gabriella Szylar Catherine Hyams Gillian Tomlinson Fernanda C Petersen R Andres Floto Mahdad Noursadeghi Jeremy S Brown

mBio 2019 09 24;10(5). Epub 2019 Sep 24.

Centre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College Medical School, Rayne Institute, London, United Kingdom

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September 2019