Magnus Essand

Magnus Essand

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Magnus Essand

Publications by authors named "Magnus Essand"

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LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients.

J Pathol 2019 Feb 10;247(2):228-240. Epub 2019 Jan 10.

Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.

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http://doi.wiley.com/10.1002/path.5186
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http://dx.doi.org/10.1002/path.5186DOI Listing
February 2019

Virus-Based Immunotherapy of Glioblastoma.

Cancers (Basel) 2019 Feb 5;11(2). Epub 2019 Feb 5.

Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 75185 Uppsala, Sweden.

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http://dx.doi.org/10.3390/cancers11020186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407011PMC
February 2019

Leukocyte Differentiation by Histidine-Rich Glycoprotein/Stanniocalcin-2 Complex Regulates Murine Glioma Growth through Modulation of Antitumor Immunity.

Mol Cancer Ther 2018 09 26;17(9):1961-1972. Epub 2018 Jun 26.

Uppsala University, Department of Immunology, Genetics and Pathology, Science for Life Laboratory, The Rudbeck Laboratory, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0097DOI Listing
September 2018

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.

J Clin Invest 2018 08 25;128(8):3280-3297. Epub 2018 Jun 25.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Rudbeck Laboratory, Uppsala, Sweden.

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http://dx.doi.org/10.1172/JCI97459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063507PMC
August 2018

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth.

Proc Natl Acad Sci U S A 2018 04 2;115(16):E3808-E3816. Epub 2018 Apr 2.

Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden;

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http://dx.doi.org/10.1073/pnas.1722333115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910864PMC
April 2018

Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer.

Neuroendocrinology 2017 21;105(1):54-66. Epub 2016 Jul 21.

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1159/000448430DOI Listing
March 2018

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses.

Oncoimmunology 2018 27;7(3):e1395126. Epub 2017 Nov 27.

Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1080/2162402X.2017.1395126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790348PMC
November 2017

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells.

Semin Cancer Biol 2017 08 28;45:23-35. Epub 2017 Feb 28.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2017.02.010DOI Listing
August 2017

Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice.

Br J Cancer 2017 Jun 30;117(1):51-55. Epub 2017 May 30.

Department of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.

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http://dx.doi.org/10.1038/bjc.2017.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520213PMC
June 2017

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.

Nucleic Acids Res 2017 03;45(5):2408-2422

Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 75237, Sweden.

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http://dx.doi.org/10.1093/nar/gkw1186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389558PMC
March 2017

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.

Mol Cancer Res 2016 12 26;14(12):1243-1253. Epub 2016 Aug 26.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0223DOI Listing
December 2016

Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors.

Immunotherapy 2016 12;8(12):1355-1361

Department of Immunology, Genetics & Pathology, Science for Life Laboratory, Uppsala University, SE-75185 Uppsala, Sweden.

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http://dx.doi.org/10.2217/imt-2016-0125DOI Listing
December 2016

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer.

EMBO Mol Med 2016 07 1;8(7):702-11. Epub 2016 Jul 1.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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http://dx.doi.org/10.15252/emmm.201505869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931286PMC
July 2016

Avidity characterization of genetically engineered T-cells with novel and established approaches.

BMC Immunol 2016 07 13;17(1):23. Epub 2016 Jul 13.

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s12865-016-0162-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944473PMC
July 2016

Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy.

Front Horm Res 2015 14;44:248-62. Epub 2015 Aug 14.

Department of Medical Sciences, Endocrine Oncology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1159/000403885DOI Listing
June 2016

HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice.

Virology 2016 Feb 18;489:44-50. Epub 2015 Dec 18.

Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2015.11.031DOI Listing
February 2016

Mesenchymal stromal cells support endothelial cell interactions in an intramuscular islet transplantation model.

Regen Med Res 2015 30;3. Epub 2015 Sep 30.

Department of Immunology, Genetics and Pathology, Division of Clinical Immunology, Uppsala, Sweden ; Department of Immunology, Genetics and Pathology, The Rudbeck Laboratory, Dag Hammarskjölds Väg 20, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1186/s40340-015-0010-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589952PMC
October 2015

Chimeric antigen receptor-engineered T cells for the treatment of metastatic prostate cancer.

BioDrugs 2015 Apr;29(2):75-89

Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 85, Uppsala, Sweden,

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http://dx.doi.org/10.1007/s40259-015-0122-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544486PMC
April 2015

Vector-encoded Helicobacter pylori neutrophil-activating protein promotes maturation of dendritic cells with Th1 polarization and improved migration.

J Immunol 2014 Sep 21;193(5):2287-96. Epub 2014 Jul 21.

Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, SE-75185 Uppsala, Sweden

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1400339
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http://dx.doi.org/10.4049/jimmunol.1400339DOI Listing
September 2014

Virotherapy of neuroendocrine tumors.

Authors:
Magnus Essand

Neuroendocrinology 2013 29;97(1):26-34. Epub 2012 Feb 29.

Rudbeck Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1159/000336084DOI Listing
May 2014

A hexon and fiber-modified adenovirus expressing CD40L improves the antigen presentation capacity of dendritic cells.

J Immunother 2014 Apr;37(3):155-62

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1097/CJI.0000000000000028DOI Listing
April 2014

Preclinical safety assessment of Ad[I/PPT-E1A], a novel oncolytic adenovirus for prostate cancer.

Hum Gene Ther Clin Dev 2014 Mar;25(1):7-15

1 Department of Urology, Erasmus MC , 3000 CA Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/humc.2013.181DOI Listing
March 2014

Islet engraftment and revascularization in clinical and experimental transplantation.

Cell Transplant 2013 8;22(2):243-51. Epub 2012 May 8.

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3727/096368912X640637DOI Listing
January 2014

Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice.

BMC Cancer 2014 Jan 18;14:30. Epub 2014 Jan 18.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University SE-75185 Uppsala, Sweden.

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http://dx.doi.org/10.1186/1471-2407-14-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899402PMC
January 2014

An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors.

Mol Ther 2013 Nov 2;21(11):2008-18. Epub 2013 Jul 2.

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1038/mt.2013.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831034PMC
November 2013

Tat-PTD-modified oncolytic adenovirus driven by the SCG3 promoter and ASH1 enhancer for neuroblastoma therapy.

Hum Gene Ther 2013 Aug;24(8):766-75

Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, Uppsala SE-75185, Sweden.

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http://dx.doi.org/10.1089/hum.2012.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746216PMC
August 2013

Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation.

Cancer Res 2013 Jan 20;73(2):490-5. Epub 2012 Nov 20.

Academic Unit of Inflammation & Tumor Targeting, University of Sheffield Medical School, Sheffield, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3056DOI Listing
January 2013

T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells.

Proc Natl Acad Sci U S A 2012 Sep 10;109(39):15877-81. Epub 2012 Sep 10.

Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1073/pnas.1209042109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465394PMC
September 2012

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas.

Mod Pathol 2009 Feb 24;22(2):261-72. Epub 2008 Oct 24.

Division of Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1038/modpathol.2008.174DOI Listing
February 2009

High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals.

Prostate 2009 Jan;69(1):70-81

Clinical Immunology Division, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/pros.20858DOI Listing
January 2009

Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells.

Br J Haematol 2008 Apr 26;141(2):188-99. Epub 2008 Feb 26.

Clinical Immunology Division, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07026.xDOI Listing
April 2008

CD8+ T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients.

Cancer Immunol Immunother 2008 Mar 24;57(3):399-409. Epub 2007 Aug 24.

Division of Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00262-007-0382-4DOI Listing
March 2008

A novel chromogranin-A promoter-driven oncolytic adenovirus for midgut carcinoid therapy.

Clin Cancer Res 2007 Apr;13(8):2455-62

Division of Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2532DOI Listing
April 2007

Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy.

Prostate 2007 Mar;67(4):389-95

Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/pros.20498DOI Listing
March 2007

Adenovirus-mediated CD40 ligand therapy induces tumor cell apoptosis and systemic immunity in the TRAMP-C2 mouse prostate cancer model.

Prostate 2006 Jun;66(8):831-8

Clinical Immunology Division, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://doi.wiley.com/10.1002/pros.20344
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http://dx.doi.org/10.1002/pros.20344DOI Listing
June 2006

Gene therapy and immunotherapy of prostate cancer: adenoviral-based strategies.

Authors:
Magnus Essand

Acta Oncol 2005 ;44(6):610-27

Clinical Immunology Division, Rudbeck Laboratory, Uppsala University, Sweden.

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http://dx.doi.org/10.1080/02841860510007477DOI Listing
January 2006

Simultaneous generation of cytomegalovirus-specific CD8+ and CD4+ T lymphocytes by use of dendritic cells comodified with pp65 mRNA and pp65 protein.

J Infect Dis 2005 Dec 21;192(11):1912-20. Epub 2005 Oct 21.

Division of Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1086/497700DOI Listing
December 2005

The immunotherapy of prostate and bladder cancer.

BJU Int 2005 Oct;96(5):728-35

Clinical Immunology Division, Department of Oncology, Radiology and Clinical Immunology, Rudbeck Laboratory, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1111/j.1464-410X.2005.05772.xDOI Listing
October 2005

CpG oligonucleotide therapy cures subcutaneous and orthotopic tumors and evokes protective immunity in murine bladder cancer.

J Immunother 2005 Jan-Feb;28(1):20-7

Rudbeck Laboratory, Clinical Immunology Division, Uppsala University, 751 85 Uppsala, Sweden.

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August 2005

Gene expression in midgut carcinoid tumors: potential targets for immunotherapy.

Acta Oncol 2005 ;44(1):32-40

Division of Clinical Immunology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1080/02841860510007404DOI Listing
May 2005

Generation of cytotoxic T lymphocytes specific for the prostate and breast tissue antigen TARP.

Prostate 2004 Oct;61(2):161-70

Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/pros.20091DOI Listing
October 2004

A novel TARP-promoter-based adenovirus against hormone-dependent and hormone-refractory prostate cancer.

Mol Ther 2004 Aug;10(2):355-64

Clinical Immunology, Rudbeck Laboratory, Uppsala University, SE-75185, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ymthe.2004.05.022DOI Listing
August 2004

Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment.

J Immunol 2004 Jun;172(11):7200-5

Clinical Immunology Division, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.4049/jimmunol.172.11.7200DOI Listing
June 2004

Characterization of the androgen-regulated prostate-specific T cell receptor gamma-chain alternate reading frame protein (TARP) promoter.

Endocrinology 2003 Aug;144(8):3433-40

Clinical Immunology, Rudbeck Laboratory, Uppsala University, SE-75185 Uppsala, Sweden.

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http://dx.doi.org/10.1210/en.2003-0121DOI Listing
August 2003

Ex vivo stimulation of cytomegalovirus (CMV)-specific T cells using CMV pp65-modified dendritic cells as stimulators.

Br J Haematol 2003 May;121(3):428-38

Clinical Immunology Division, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04300.xDOI Listing
May 2003