Maegan Harden

Maegan Harden

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Maegan Harden

Maegan Harden

Publications by authors named "Maegan Harden"

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18Publications

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Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors.

Authors:
Jordi Merino Kathleen A Jablonski Josep M Mercader Steven E Kahn Ling Chen Maegan Harden Linda M Delahanty Maria Rosario G Araneta Geoffrey A Walford Suzanne B R Jacobs Uzoma N Ibebuogu Paul W Franks William C Knowler Jose C Florez

Diabetes 2019 Oct 21. Epub 2019 Oct 21.

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA

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http://dx.doi.org/10.2337/db19-0097DOI Listing
October 2019

A Polygenic Lipodystrophy Genetic Risk Score Characterizes Risk Independent of BMI in the Diabetes Prevention Program.

Authors:
Shylaja Srinivasan Kathleen A Jablonski William C Knowler Samuel Dagogo-Jack Steven E Kahn Edward J Boyko George A Bray Edward S Horton Marie-France Hivert Ronald Goldberg Ling Chen Josep Mercader Maegan Harden Jose C Florez

J Endocr Soc 2019 Sep 24;3(9):1663-1677. Epub 2019 Jun 24.

Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1210/js.2019-00069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694040PMC
September 2019

Outcomes of patient self-referral for the diagnosis of several rare inherited kidney diseases.

Authors:
Anthony J Bleyer Kendrah Kidd Victoria Robins Lauren Martin Abbigail Taylor Annie Santi Georgeanna Tsoumas Alese Hunt Elizabeth Swain Marwan Abbas Ebun Akinbola Sri Vidya Shahriar Moossavi Anthony J Bleyer Martina Živná Hana Hartmannová Kateřina Hodaňová Petr Vyleťal Miroslav Votruba Maegan Harden Brendan Blumenstiel Anna Greka Stanislav Kmoch

Genet Med 2019 Jul 24. Epub 2019 Jul 24.

Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1038/s41436-019-0617-8DOI Listing
July 2019

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.

Authors:
Derin B Keskin Annabelle J Anandappa Jing Sun Itay Tirosh Nathan D Mathewson Shuqiang Li Giacomo Oliveira Anita Giobbie-Hurder Kristen Felt Evisa Gjini Sachet A Shukla Zhuting Hu Letitia Li Phuong M Le Rosa L Allesøe Alyssa R Richman Monika S Kowalczyk Sara Abdelrahman Jack E Geduldig Sarah Charbonneau Kristine Pelton J Bryan Iorgulescu Liudmila Elagina Wandi Zhang Oriol Olive Christine McCluskey Lars R Olsen Jonathan Stevens William J Lane Andres M Salazar Heather Daley Patrick Y Wen E Antonio Chiocca Maegan Harden Niall J Lennon Stacey Gabriel Gad Getz Eric S Lander Aviv Regev Jerome Ritz Donna Neuberg Scott J Rodig Keith L Ligon Mario L Suvà Kai W Wucherpfennig Nir Hacohen Edward F Fritsch Kenneth J Livak Patrick A Ott Catherine J Wu David A Reardon

Nature 2019 01 19;565(7738):234-239. Epub 2018 Dec 19.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://www.nature.com/articles/s41586-018-0792-9
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http://dx.doi.org/10.1038/s41586-018-0792-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546179PMC
January 2019

Noninvasive Immunohistochemical Diagnosis and Novel Mutations Causing Autosomal Dominant Tubulointerstitial Kidney Disease.

Authors:
Martina Živná Kendrah Kidd Anna Přistoupilová Veronika Barešová Mathew DeFelice Brendan Blumenstiel Maegan Harden Peter Conlon Peter Lavin Dervla M Connaughton Hana Hartmannová Kateřina Hodaňová Viktor Stránecký Alena Vrbacká Petr Vyleťal Jan Živný Miroslav Votruba Jana Sovová Helena Hůlková Victoria Robins Rebecca Perry Andrea Wenzel Bodo B Beck Tomáš Seeman Ondřej Viklický Sylvie Rajnochová-Bloudíčková Gregory Papagregoriou Constantinos C Deltas Seth L Alper Anna Greka Anthony J Bleyer Stanislav Kmoch

J Am Soc Nephrol 2018 09 2;29(9):2418-2431. Epub 2018 Jul 2.

Research Unit for Rare Diseases, Department of Pediatrics and Adolescent Medicine, First Faculty of Medicine.

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http://dx.doi.org/10.1681/ASN.2018020180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115665PMC
September 2018

Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma.

Authors:
Patrick A Ott Zhuting Hu Derin B Keskin Sachet A Shukla Jing Sun David J Bozym Wandi Zhang Adrienne Luoma Anita Giobbie-Hurder Lauren Peter Christina Chen Oriol Olive Todd A Carter Shuqiang Li David J Lieb Thomas Eisenhaure Evisa Gjini Jonathan Stevens William J Lane Indu Javeri Kaliappanadar Nellaiappan Andres M Salazar Heather Daley Michael Seaman Elizabeth I Buchbinder Charles H Yoon Maegan Harden Niall Lennon Stacey Gabriel Scott J Rodig Dan H Barouch Jon C Aster Gad Getz Kai Wucherpfennig Donna Neuberg Jerome Ritz Eric S Lander Edward F Fritsch Nir Hacohen Catherine J Wu

Nature 2018 03;555(7696):402

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http://dx.doi.org/10.1038/nature25145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064631PMC
March 2018

A Loss-of-Function Splice Acceptor Variant in Is Protective for Type 2 Diabetes.

Authors:
Josep M Mercader Rachel G Liao Avery D Bell Zachary Dymek Karol Estrada Taru Tukiainen Alicia Huerta-Chagoya Hortensia Moreno-Macías Kathleen A Jablonski Robert L Hanson Geoffrey A Walford Ignasi Moran Ling Chen Vineeta Agarwala María Luisa Ordoñez-Sánchez Rosario Rodríguez-Guillen Maribel Rodríguez-Torres Yayoi Segura-Kato Humberto García-Ortiz Federico Centeno-Cruz Francisco Barajas-Olmos Lizz Caulkins Sobha Puppala Pierre Fontanillas Amy L Williams Sílvia Bonàs-Guarch Chris Hartl Stephan Ripke Katherine Tooley Jacqueline Lane Carlos Zerrweck Angélica Martínez-Hernández Emilio J Córdova Elvia Mendoza-Caamal Cecilia Contreras-Cubas María E González-Villalpando Ivette Cruz-Bautista Liliana Muñoz-Hernández Donaji Gómez-Velasco Ulises Alvirde Brian E Henderson Lynne R Wilkens Loic Le Marchand Olimpia Arellano-Campos Laura Riba Maegan Harden Stacey Gabriel Hanna E Abboud Maria L Cortes Cristina Revilla-Monsalve Sergio Islas-Andrade Xavier Soberon Joanne E Curran Christopher P Jenkinson Ralph A DeFronzo Donna M Lehman Craig L Hanis Graeme I Bell Michael Boehnke John Blangero Ravindranath Duggirala Richa Saxena Daniel MacArthur Jorge Ferrer Steven A McCarroll David Torrents William C Knowler Leslie J Baier Noel Burtt Clicerio González-Villalpando Christopher A Haiman Carlos A Aguilar-Salinas Teresa Tusié-Luna Jason Flannick Suzanne B R Jacobs Lorena Orozco David Altshuler Jose C Florez

Diabetes 2017 11 24;66(11):2903-2914. Epub 2017 Aug 24.

Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA

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http://dx.doi.org/10.2337/db17-0187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652606PMC
November 2017

An immunogenic personal neoantigen vaccine for patients with melanoma.

Authors:
Patrick A Ott Zhuting Hu Derin B Keskin Sachet A Shukla Jing Sun David J Bozym Wandi Zhang Adrienne Luoma Anita Giobbie-Hurder Lauren Peter Christina Chen Oriol Olive Todd A Carter Shuqiang Li David J Lieb Thomas Eisenhaure Evisa Gjini Jonathan Stevens William J Lane Indu Javeri Kaliappanadar Nellaiappan Andres M Salazar Heather Daley Michael Seaman Elizabeth I Buchbinder Charles H Yoon Maegan Harden Niall Lennon Stacey Gabriel Scott J Rodig Dan H Barouch Jon C Aster Gad Getz Kai Wucherpfennig Donna Neuberg Jerome Ritz Eric S Lander Edward F Fritsch Nir Hacohen Catherine J Wu

Nature 2017 07 5;547(7662):217-221. Epub 2017 Jul 5.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/nature22991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577644PMC
July 2017

Catechol-O-methyltransferase association with hemoglobin A1c.

Authors:
Kathryn T Hall Kathleen A Jablonski Ling Chen Maegan Harden Benjamin R Tolkin Ted J Kaptchuk George A Bray Paul M Ridker Jose C Florez Kenneth J Mukamal Daniel I Chasman

Metabolism 2016 07 14;65(7):961-967. Epub 2016 Apr 14.

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.metabol.2016.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924514PMC
July 2016

The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.

Authors:
Geoffrey A Walford Natalia Colomo Jennifer N Todd Liana K Billings Marlene Fernandez Bindu Chamarthi A Sofia Warner Jaclyn Davis Katherine R Littleton Alicia M Hernandez Rebecca R Fanelli Amelia Lanier Corinne Barbato Rachel J Ackerman Sabina Q Khan Rosa Bui Laurel Garber Elliot S Stolerman Allan F Moore Chunmei Huang Varinderpal Kaur Maegan Harden Andrew Taylor Ling Chen Alisa K Manning Paul Huang Deborah Wexler Rita M McCarthy Janet Lo Melissa K Thomas Richard W Grant Allison Goldfine Margo S Hudson Jose C Florez

PLoS One 2015 26;10(3):e0121553. Epub 2015 Mar 26.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Diabetes Research Center, Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374872PMC
March 2016

Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials.

Authors:
George D Papandonatos Qing Pan Nicholas M Pajewski Linda M Delahanty Inga Peter Bahar Erar Shafqat Ahmad Maegan Harden Ling Chen Pierre Fontanillas Lynne E Wagenknecht Steven E Kahn Rena R Wing Kathleen A Jablonski Gordon S Huggins William C Knowler Jose C Florez Jeanne M McCaffery Paul W Franks

Diabetes 2015 Dec 7;64(12):4312-21. Epub 2015 Aug 7.

Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Skåne University Hospital Malmö, Malmö, Sweden Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA

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http://dx.doi.org/10.2337/db15-0441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657576PMC
December 2015

Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation.

Authors:
Eliezer M Van Allen Hadrien G Golay Yan Liu Shohei Koyama Karrie Wong Amaro Taylor-Weiner Marios Giannakis Maegan Harden Vanesa Rojas-Rudilla Aaron Chevalier Tran Thai Christine Lydon Stacy Mach Ada G Avila Joshua A Wong Alexandra R Rabin Joshua Helmkamp Lynette Sholl Scott L Carter Geoffrey Oxnard Pasi Janne Gad Getz Neal Lindeman Peter S Hammerman Levi A Garraway F Stephen Hodi Scott J Rodig Glenn Dranoff Kwok-Kin Wong David A Barbie

Cancer Immunol Res 2015 Aug 26;3(8):855-63. Epub 2015 May 26.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. Broad Institute of MIT and Harvard, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527885PMC
August 2015

African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans.

Authors:
Arti Tandon Ching J Chen Alan Penman Heather Hancock Maurice James Deeba Husain Christopher Andreoli Xiaohui Li Jane Z Kuo Omolola Idowu Daniel Riche Evangelia Papavasilieou Stacey Brauner Sataria O Smith Suzanne Hoadley Cole Richardson Troy Kieser Vanessa Vazquez Cheryl Chi Marlene Fernandez Maegan Harden Mary Frances Cotch David Siscovick Herman A Taylor James G Wilson David Reich Tien Y Wong Ronald Klein Barbara E K Klein Jerome I Rotter Nick Patterson Lucia Sobrin

Invest Ophthalmol Vis Sci 2015 Jun;56(6):3999-4005

Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1167/iovs.15-16674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477259PMC
June 2015

The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.

Authors:
Shereen Ezzat Lei Zheng Jose C Florez Norbert Stefan Thomas Mayr Maw Maw Hliang Kathleen Jablonski Maegan Harden Alena Stančáková Markku Laakso Hans-Ulrich Haring Axel Ullrich Sylvia L Asa

Cell Metab 2013 Jun;17(6):929-40

Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2M9, Canada.

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http://dx.doi.org/10.1016/j.cmet.2013.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005358PMC
June 2013

Close association of olfactory placode precursors and cranial neural crest cells does not predestine cell mixing.

Authors:
Maegan V Harden Luisa Pereiro Mirana Ramialison Jochen Wittbrodt Megana K Prasad Andrew S McCallion Kathleen E Whitlock

Dev Dyn 2012 Jul 22;241(7):1143-54. Epub 2012 May 22.

Department of Molecular Biology and Genetics, 445/449 Biotechnology Building, Cornell University, Ithaca, New York, USA.

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http://dx.doi.org/10.1002/dvdy.23797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240535PMC
July 2012

Olfactory imprinting is correlated with changes in gene expression in the olfactory epithelia of the zebrafish.

Authors:
Maegan V Harden Lucy A Newton Russell C Lloyd Kathleen E Whitlock

J Neurobiol 2006 Nov;66(13):1452-66

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1002/neu.20328DOI Listing
November 2006

UNC-6/netrin and SLT-1/slit guidance cues orient axon outgrowth mediated by MIG-10/RIAM/lamellipodin.

Authors:
Christopher C Quinn Douglas S Pfeil Esteban Chen Elizabeth L Stovall Maegan V Harden Megan K Gavin Wayne C Forrester Elizabeth F Ryder Martha C Soto William G Wadsworth

Curr Biol 2006 May 23;16(9):845-53. Epub 2006 Mar 23.

Department of Pathology, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1016/j.cub.2006.03.025DOI Listing
May 2006

A role for foxd3 and sox10 in the differentiation of gonadotropin-releasing hormone (GnRH) cells in the zebrafish Danio rerio.

Authors:
Kathleen E Whitlock Kalmia M Smith Hannah Kim Maegan V Harden

Development 2005 Dec 16;132(24):5491-502. Epub 2005 Nov 16.

Department of Molecular Biology and Genetics, 445 Biotechnology Building, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1242/dev.02158DOI Listing
December 2005