Madia Lozupone

Madia Lozupone

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Madia Lozupone

Madia Lozupone

Publications by authors named "Madia Lozupone"

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Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs.

Expert Opin Pharmacother 2019 Jun 19;20(9):1091-1107. Epub 2019 Apr 19.

a Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs , University of Bari "Aldo Moro" , Bari , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2019.1
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http://dx.doi.org/10.1080/14656566.2019.1598377DOI Listing
June 2019

Disease-modifying therapies for tauopathies: agents in the pipeline.

Expert Rev Neurother 2019 May 25;19(5):397-408. Epub 2019 Apr 25.

g Department of Neurological Sciences , Santa Maria University Hospital , Terni , Italy.

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http://dx.doi.org/10.1080/14737175.2019.1606715DOI Listing
May 2019

Do BACE inhibitor failures in Alzheimer's patients challenge the amyloid hypothesis of the disease?

Expert Rev Neurother 2019 May 21. Epub 2019 May 21.

c Geriatric Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo , Foggia , Italy.

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http://dx.doi.org/10.1080/14737175.2019.1621751DOI Listing
May 2019

Amyloid-β immunotherapy for alzheimer disease: Is it now a long shot?

Ann Neurol 2019 Mar 28;85(3):303-315. Epub 2019 Jan 28.

Department of Research and Development, Chiesi Pharmaceuticals, Parma, Italy.

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http://dx.doi.org/10.1002/ana.25410DOI Listing
March 2019

Episodic memory and learning rates in amyotrophic lateral sclerosis without dementia.

Cortex 2019 Mar 19;117:257-265. Epub 2019 Mar 19.

Neurodegenerative Disease Unit, Department of Clinical Research in Neurology, University of Bari "Aldo Moro", Lecce, Italy; Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00109452193010
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http://dx.doi.org/10.1016/j.cortex.2019.03.003DOI Listing
March 2019

Executive Dysfunction Detected with the Frontal Assessment Battery in Alzheimer's Disease Versus Vascular Dementia.

J Alzheimers Dis 2018 ;62(2):699-711

Department of Medical Sciences, Geriatric Unit and Laboratory of Gerontology and Geriatrics, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.3233/JAD-170365DOI Listing
February 2019

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease.

Nat Rev Neurol 2019 Feb;15(2):73-88

Department of Research and Development, Chiesi Farmaceutici, Parma, Italy.

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http://dx.doi.org/10.1038/s41582-018-0116-6DOI Listing
February 2019

Botulinum Toxin Type A for the Treatment of Lower Limb Spasticity after Stroke.

Drugs 2019 Feb;79(2):143-160

Physical Medicine and Rehabilitation Section, "OORR Hospital", University of Foggia, Viale Pinto, 71100, Foggia, Italy.

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http://link.springer.com/10.1007/s40265-018-1042-z
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http://dx.doi.org/10.1007/s40265-018-1042-zDOI Listing
February 2019

Understanding frailty to predict and prevent dementia.

Lancet Neurol 2019 Feb;18(2):133-134

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy.

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http://dx.doi.org/10.1016/S1474-4422(18)30446-0DOI Listing
February 2019

The Role of Biomarkers in Psychiatry.

Adv Exp Med Biol 2019;1118:135-162

Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.1007/978-3-030-05542-4_7DOI Listing
January 2019

Nutritional interventions and cognitive-related outcomes in patients with late-life cognitive disorders: A systematic review.

Neurosci Biobehav Rev 2018 12 3;95:480-498. Epub 2018 Nov 3.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Geriatric Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy; Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari "Aldo Moro", "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01497634183050
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http://dx.doi.org/10.1016/j.neubiorev.2018.10.022DOI Listing
December 2018

Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease.

Mol Neurobiol 2018 May 19;55(5):4333-4344. Epub 2017 Jun 19.

Complex Structure of Geriatrics, Research Laboratory, Department of Medical Sciences, I.R.C.C.S. Casa Sollievo della Sofferenza, Viale Cappuccini 1, 71013, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.1007/s12035-017-0547-xDOI Listing
May 2018

Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline.

J Alzheimers Dis 2017 ;59(1):121-130

Department of Clinical Research in Neurology, Unit of Neurodegenerative Disease, University of Bari "Aldo Moro" at "Pia Fondazione Card. G. Panico", Tricase, Lecce, Italy.

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http://dx.doi.org/10.3233/JAD-170153DOI Listing
April 2018

Bipolar Disorder and Frontotemporal Dementia: An Intriguing Association.

J Alzheimers Dis 2017 ;55(3):973-979

Department of Basic Medical Science, Neuroscience and Sense Organs, Neurodegenerative Disease Unit, University of Bari "Aldo Moro", Bari, Italy.

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http://dx.doi.org/10.3233/JAD-160860DOI Listing
February 2018

An Old Challenge with New Promises: A Systematic Review on Comprehensive Geriatric Assessment in Long-Term Care Facilities.

Rejuvenation Res 2018 Feb 28;21(1):3-14. Epub 2017 Jul 28.

1 Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro , Bari, Italy .

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http://dx.doi.org/10.1089/rej.2017.1964DOI Listing
February 2018

Emerging biomarkers and screening for cognitive frailty.

Aging Clin Exp Res 2017 Dec 4;29(6):1075-1086. Epub 2017 Mar 4.

Shanghai Key Laboratory of Clinical Geriatrics, Department of Geriatrics, Huadong Hospital, and Research Center of Aging and Medicine, Shanghai Institute of Geriatrics and Gerontology, Shanghai Medical College, Fudan University, Shanghai, 200040, China.

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http://dx.doi.org/10.1007/s40520-017-0741-8DOI Listing
December 2017

Psychotropic drugs and CYP2D6 in late-life psychiatric and neurological disorders. What do we know?

Expert Opin Drug Saf 2017 Dec 12;16(12):1373-1385. Epub 2017 Oct 12.

a Complex Structure of Geriatrics, Department of Medical Sciences , IRCCS "Casa Sollievo della Sofferenza" , San Giovanni Rotondo , Foggia , Italy.

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http://dx.doi.org/10.1080/14740338.2017.1389891DOI Listing
December 2017

Additive Role of a Potentially Reversible Cognitive Frailty Model and Inflammatory State on the Risk of Disability: The Italian Longitudinal Study on Aging.

Am J Geriatr Psychiatry 2017 Nov 6;25(11):1236-1248. Epub 2017 Jul 6.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Gerontology-Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2017.05.018DOI Listing
November 2017

Cognitive frailty: a potential target for secondary prevention of dementia.

Expert Opin Drug Metab Toxicol 2017 10 5;13(10):1023-1027. Epub 2017 Sep 5.

b Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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http://dx.doi.org/10.1080/17425255.2017.1372424DOI Listing
October 2017

Klotho Gene and Selective Serotonin Reuptake Inhibitors: Response to Treatment in Late-Life Major Depressive Disorder.

Mol Neurobiol 2017 03 3;54(2):1340-1351. Epub 2016 Feb 3.

Gerontology-Geriatric Research Laboratory, Department of Medical Sciences, I.R.C.C.S. "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.1007/s12035-016-9711-yDOI Listing
March 2017

Pharmacogenetics of neurological and psychiatric diseases at older age: has the time come?

Expert Opin Drug Metab Toxicol 2017 Mar 20;13(3):259-277. Epub 2016 Oct 20.

c Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , San Giovanni Rotondo , Italy.

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http://dx.doi.org/10.1080/17425255.2017.1246533DOI Listing
March 2017

Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease.

Biomed Res Int 2016 26;2016:3245935. Epub 2016 Jun 26.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.

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http://dx.doi.org/10.1155/2016/3245935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939203PMC
February 2017

Reversible Cognitive Frailty, Dementia, and All-Cause Mortality. The Italian Longitudinal Study on Aging.

J Am Med Dir Assoc 2017 01;18(1):89.e1-89.e8

Gerontology-Geriatrics Research Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2016.10.012DOI Listing
January 2017

Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.

Expert Rev Neurother 2016 ;16(3):259-77

a Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences , IRCCS 'Casa Sollievo della Sofferenza' , San Giovanni Rotondo , Foggia , Italy.

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http://dx.doi.org/10.1586/14737175.2016.1140039DOI Listing
December 2016

Psychiatry meets pharmacogenetics for the treatment of revolving door patients with psychiatric disorders.

Expert Rev Neurother 2016 12 11;16(12):1357-1369. Epub 2016 Jul 11.

a Geriatric Unit and Geriatric Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.

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http://dx.doi.org/10.1080/14737175.2016.1204913DOI Listing
December 2016

Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer's disease patients.

Expert Opin Emerg Drugs 2016 Dec 6;21(4):377-391. Epub 2016 Oct 6.

a Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs , University of Bari 'Aldo Moro' , Bari , Italy.

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http://dx.doi.org/10.1080/14728214.2016.1241232DOI Listing
December 2016

Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy.

Immunotherapy 2016 09;8(9):1119-34

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, & Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.2217/imt-2016-0019DOI Listing
September 2016

High doses of incobotulinumtoxinA for the treatment of post-stroke spasticity: are they safe and effective?

Expert Opin Drug Metab Toxicol 2016 Aug 17;12(8):843-6. Epub 2016 Jun 17.

c Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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http://dx.doi.org/10.1080/17425255.2016.1198318DOI Listing
August 2016

Progresses in treating agitation: a major clinical challenge in Alzheimer's disease.

Expert Opin Pharmacother 2015 21;16(17):2581-8. Epub 2015 Sep 21.

a 1 University of Bari Aldo Moro, Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , Bari, Italy ,

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http://dx.doi.org/10.1517/14656566.2015.1092520DOI Listing
June 2016

Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?

Expert Opin Pharmacother 2016 15;17(4):457-61. Epub 2016 Feb 15.

a Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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http://dx.doi.org/10.1517/14656566.2016.1146686DOI Listing
June 2016

Psychopathological profile and health-related quality of life (HRQOL) in patients with hepatocellular carcinoma (HCC) and cirrhosis.

Clin Exp Med 2015 Feb 10;15(1):65-72. Epub 2013 Dec 10.

Department of Biomedical Sciences and Human Oncology, Clinica Medica "A. Murri", University of Bari, Policlinico, 70124, Bari, Italy,

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http://dx.doi.org/10.1007/s10238-013-0267-0DOI Listing
February 2015