Publications by authors named "Madhurima Saxena"

15Publications

Epigenetic Signatures and Plasticity of Intestinal and Other Stem Cells.

Annu Rev Physiol 2020 Nov 24. Epub 2020 Nov 24.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA; email:

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November 2020

Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.

Cell Mol Gastroenterol Hepatol 2020 25;9(4):587-609. Epub 2019 Nov 25.

Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, New York; Department of Physiology and Biophysics, Stony Brook University Renaissance School of Medicine, Stony Brook, New York. Electronic address:

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November 2019

Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.

Genes Dev 2018 11 26;32(21-22):1430-1442. Epub 2018 Oct 26.

Department of Medical Oncology, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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November 2018

Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.

Genes Dev 2017 12 10;31(23-24):2391-2404. Epub 2018 Jan 10.

Department of Medical Oncology, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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December 2017

Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.

Cell Stem Cell 2017 07 22;21(1):65-77.e5. Epub 2017 Jun 22.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

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July 2017

Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells.

Cell Rep 2016 08 11;16(8):2053-2060. Epub 2016 Aug 11.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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August 2016

Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells.

Cell 2016 Jun 19;165(6):1389-1400. Epub 2016 May 19.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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June 2016

Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells.

PLoS One 2014 4;9(6):e98861. Epub 2014 Jun 4.

Department of Molecular and Cellular Physiology, LSU Health Sciences Center School of Medicine in Shreveport, Shreveport, Louisiana, United States of America; The Feist-Weiller Cancer Center, LSU Health Sciences Center School of Medicine in Shreveport, Shreveport, Louisiana, United States of America.

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August 2015

SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression.

Mol Endocrinol 2013 Mar 22;27(3):480-90. Epub 2013 Jan 22.

Departments of Molecular and Cellular Physiology, Louisiana State University Health, Sciences Center School of Medicine in Shreveport, Shreveport, LA 71130, USA.

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March 2013

Chromosomal aberration in the post-implantation embryos sired by tamoxifen treated male rats.

Mutat Res 2010 Dec 27;703(2):169-73. Epub 2010 Aug 27.

Division of Neuroendocrinology, National Institute for Research in Reproductive Health (ICMR), Parel, Mumbai 400012, India.

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December 2010

Disrupted imprinting status at the H19 differentially methylated region is associated with the resorbed embryo phenotype in rats.

Reprod Fertil Dev 2010 ;22(6):939-48

Division of Neuroendocrinology, National Institute for Research in Reproductive Health, Indian Council of Medical Research, Parel, Mumbai, India.

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September 2010

SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling.

Proc Natl Acad Sci U S A 2010 May 3;107(20):9216-21. Epub 2010 May 3.

Department of Molecular and Cellular Physiology, School of Medicine, and Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.

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May 2010