Maarten van den Berge

Maarten van den Berge

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Maarten van den Berge

Publications by authors named "Maarten van den Berge"

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Genetic profiling for disease stratification in chronic obstructive pulmonary disease and asthma.

Curr Opin Pulm Med 2019 May;25(3):317-322

Faculty of Science, University of Technology Sydney, Respiratory Bioinformatics and Molecular Biology, Ultimo, NSW, Australia.

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http://dx.doi.org/10.1097/MCP.0000000000000568DOI Listing
May 2019

Applying the CAMP trial asthma remission prediction model to the Dutch asthma remission studies.

J Allergy Clin Immunol 2019 May 12;143(5):1973-1975. Epub 2019 Mar 12.

Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.040DOI Listing
May 2019

A review on the pathophysiology of asthma remission.

Pharmacol Ther 2019 May 7. Epub 2019 May 7.

University of Groningen, University Medical Center Groningen, Groningen, Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, the Netherlands.

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http://dx.doi.org/10.1016/j.pharmthera.2019.05.002DOI Listing
May 2019

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers.

Respir Res 2019 Apr 10;20(1):70. Epub 2019 Apr 10.

Department of Pathology & Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12931-019-1038-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456980PMC
April 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

Role of microRNAs and exosomes in asthma.

Curr Opin Pulm Med 2019 Jan;25(1):87-93

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1097/MCP.0000000000000532DOI Listing
January 2019

Functional CT imaging for identification of the spatial determinants of small-airways disease in adults with asthma.

J Allergy Clin Immunol 2019 Jan 22. Epub 2019 Jan 22.

NIHR Respiratory Biomedical Research Centre (BRC), Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.014DOI Listing
January 2019

Associations of AMP and adenosine induced dyspnea sensation to large and small airways dysfunction in asthma.

BMC Pulm Med 2019 Jan 28;19(1):23. Epub 2019 Jan 28.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, PO box 30.0001, 9700, RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12890-019-0783-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348600PMC
January 2019

Predictors of clinical response to extrafine and non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma.

Respir Res 2018 Dec 18;19(1):256. Epub 2018 Dec 18.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, PO Box 30.0001, 9700, RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12931-018-0961-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299530PMC
December 2018

Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD.

Respirology 2018 Nov 26;23(11):1023-1031. Epub 2018 Apr 26.

Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/resp.13312DOI Listing
November 2018

microRNA-mRNA regulatory networks underlying chronic mucus hypersecretion in COPD.

Eur Respir J 2018 09 6;52(3). Epub 2018 Sep 6.

Dept of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.01556-2017DOI Listing
September 2018

Nasal epithelium as a proxy for bronchial epithelium for smoking-induced gene expression and expression Quantitative Trait Loci.

J Allergy Clin Immunol 2018 Jul 6;142(1):314-317.e15. Epub 2018 Mar 6.

Department of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands; GRIAC (Groningen Research Institute for Asthma and COPD), Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands; Department of Pathology & Medical Biology, Section of Medical Biology, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2018.01.047DOI Listing
July 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Realising the potential of various inhaled airway challenge agents through improved delivery to the lungs.

Pulm Pharmacol Ther 2018 04 10;49:27-35. Epub 2018 Jan 10.

University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Hanzeplein 1, 9700 RB Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Hanzeplein 1, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.pupt.2018.01.004DOI Listing
April 2018

The asthma-obesity relationship: underlying mechanisms and treatment implications.

Curr Opin Pulm Med 2018 01;24(1):42-49

University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, The Netherlands.

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http://dx.doi.org/10.1097/MCP.0000000000000446DOI Listing
January 2018

Lung tissue gene-expression signature for the ageing lung in COPD.

Thorax 2017 Dec 6. Epub 2017 Dec 6.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/thoraxjnl-2017-210074DOI Listing
December 2017

microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach.

Sci Rep 2017 10 9;7(1):12871. Epub 2017 Oct 9.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1038/s41598-017-13265-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634489PMC
October 2017

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice.

Am J Physiol Lung Cell Mol Physiol 2017 Sep 8;313(3):L559-L580. Epub 2017 Jun 8.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00466.2016DOI Listing
September 2017

Targeting the small airways with dry powder adenosine: a challenging concept.

Eur Clin Respir J 2017 6;4(1):1369328. Epub 2017 Sep 6.

Department of Pulmonary Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1080/20018525.2017.1369328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642194PMC
September 2017

Extrafine compared to non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma.

Respir Med 2017 Sep 8;130:35-42. Epub 2017 Jul 8.

University of Groningen, University Medical Centre Groningen, Department of Pulmonary Diseases, PO Box 30.0001, 9700 RB Groningen, The Netherlands; University of Groningen, University Medical Centre Groningen, Groningen Research Institute for Asthma and COPD, PO Box 30.0001, 9700 RB Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.07.005DOI Listing
September 2017

Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airways.

J Allergy Clin Immunol 2017 07 19;140(1):280-283.e3. Epub 2016 Dec 19.

Department of Pharmacokinetics, Toxicology, and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.11.020DOI Listing
July 2017

Childhood factors associated with complete and clinical asthma remission at 25 and 49 years.

Eur Respir J 2017 06 8;49(6). Epub 2017 Jun 8.

University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01974-2016DOI Listing
June 2017

Year in review 2016: Chronic obstructive pulmonary disease and asthma.

Respirology 2017 05 28;22(4):820-828. Epub 2017 Mar 28.

Department of Medicine, Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/resp.13037DOI Listing
May 2017

Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.

EBioMedicine 2017 May 12;19:139-145. Epub 2017 Apr 12.

UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440622PMC
May 2017

Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease.

Respir Res 2017 05 2;18(1):77. Epub 2017 May 2.

Respiratory Medicine and Allergology, Department of Clinical Sciences Lund, BMC, D12, Lund University, Skåne University Hospital, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1186/s12931-017-0562-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414362PMC
May 2017

Identification of Susceptibility Genes of Adult Asthma in French Canadian Women.

Can Respir J 2016 4;2016:3564341. Epub 2016 May 4.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec City, QC, Canada G1V 4G5; Department of Molecular Medicine, Laval University, Quebec City, QC, Canada G1V 0A6.

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http://dx.doi.org/10.1155/2016/3564341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904514PMC
March 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

Airway wall thickness on HRCT scans decreases with age and increases with smoking.

BMC Pulm Med 2017 02 1;17(1):27. Epub 2017 Feb 1.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12890-017-0363-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286807PMC
February 2017

The Asthma COPD Overlap Syndrome: ACOS Epidemiology and Historical Perspective.

Tanaffos 2017 ;16(Suppl 1):S22-S23

Department of Pulmonary diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684724PMC
January 2017

The Asthma COPD Overlap Syndrome: ACOS. Epidemiology and Historical Perspective.

Tanaffos 2017 ;16(Suppl 1):S26-S28

Department of Pulmonary diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684730PMC
January 2017

Airway hyperresponsiveness in chronic obstructive pulmonary disease: A marker of asthma-chronic obstructive pulmonary disease overlap syndrome?

J Allergy Clin Immunol 2016 12 24;138(6):1571-1579.e10. Epub 2016 May 24.

UBC James Hogg Research Center & the Institute for Heart and Lung Health, St Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.04.022DOI Listing
December 2016

Viral mimic poly-(I:C) attenuates airway epithelial T-cell suppressive capacity: implications for asthma.

Eur Respir J 2016 12 6;48(6):1785-1788. Epub 2016 Oct 6.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.00841-2016DOI Listing
December 2016

Fibulin-5 as a potential therapeutic target in COPD.

Expert Opin Ther Targets 2016 09 25;20(9):1031-3. Epub 2016 Mar 25.

a Department of Pathology and Medical Biology , University of Groningen, University Medical Center Groningen , Groningen , The Netherlands.

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http://dx.doi.org/10.1517/14728222.2016.1164696DOI Listing
September 2016

Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.

Eur Respir J 2016 08 28;48(2):504-15. Epub 2016 Apr 28.

University of Groningen, University Medical Center Groningen, Dept of Pulmonology, Groningen, The Netherlands University of Groningen, University Medical Center Groningen GRIAC Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.01541-2015DOI Listing
August 2016

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis.

Thorax 2016 Apr 21;71(4):312-22. Epub 2016 Jan 21.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/thoraxjnl-2015-206958DOI Listing
April 2016

Cardiac impact of inhaled therapy in the largest randomised placebo-controlled trial in COPD history: have we reached the SUMMIT?

ERJ Open Res 2016 Apr 26;2(2). Epub 2016 May 26.

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Dept of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1183/23120541.00055-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005175PMC
April 2016

The asthma-COPD overlap syndrome: how is it defined and what are its clinical implications?

J Asthma Allergy 2016 10;9:27-35. Epub 2016 Feb 10.

Department of Pulmonary Diseases, Martini Hospital, Groningen, the Netherlands.

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http://dx.doi.org/10.2147/JAA.S78900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755465PMC
March 2016

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

Am J Physiol Lung Cell Mol Physiol 2015 Nov 28;309(10):L1112-23. Epub 2015 Aug 28.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, The Netherlands; and University of Groningen, University Medical Center Groningen, Groningen, Groningen Research Institute for Asthma Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00077.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652154PMC
November 2015

Effects of ageing and smoking on pulmonary computed tomography scans using parametric response mapping.

Eur Respir J 2015 Oct 25;46(4):1193-6. Epub 2015 Jun 25.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands Both authors contributed equally

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http://erj.ersjournals.com/content/46/4/1193.full.pdf
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http://erj.ersjournals.com/lookup/doi/10.1183/09031936.00009
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http://dx.doi.org/10.1183/09031936.00009415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591191PMC
October 2015

The different faces of the asthma-COPD overlap syndrome.

Eur Respir J 2015 Sep;46(3):587-90

Dept of Pulmonology, University of Groningen, University Medical Center Groningen, GRIAC Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.00810-2015DOI Listing
September 2015

Revisiting the Dutch hypothesis.

J Allergy Clin Immunol 2015 Sep;136(3):521-9

University of Groningen, GRIAC Research Institute, University Medical Center Groningen, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, and the Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2015.06.018DOI Listing
September 2015

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells.

Thorax 2015 Jul 20;70(7):668-76. Epub 2015 May 20.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/thoraxjnl-2014-205731DOI Listing
July 2015

Lower corticosteroid skin blanching response is associated with severe COPD.

PLoS One 2014 12;9(3):e91788. Epub 2014 Mar 12.

University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091788PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951419PMC
May 2015

Susceptibility to COPD: differential proteomic profiling after acute smoking.

PLoS One 2014 18;9(7):e102037. Epub 2014 Jul 18.

University of Groningen, University Medical Centre Groningen, Department of Pulmonary Diseases, Groningen Research Institute of Asthma and COPD (GRIAC), Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102037PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103835PMC
March 2015

Risk factors and early origins of chronic obstructive pulmonary disease.

Lancet 2015 Mar 11;385(9971):899-909. Epub 2014 Aug 11.

Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.1016/S0140-6736(14)60446-3DOI Listing
March 2015

Regular treatment for moderate asthma: guidelines hold true.

Lancet Respir Med 2015 Feb 4;3(2):88-89. Epub 2014 Dec 4.

University of Groningen, Department of Pulmonary Diseases, University Medical Center Groningen, and Groningen Research Institute for Asthma and COPD GRIAC, PO Box 30.001 NL-9700-RB, Groningen, Netherlands.

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http://dx.doi.org/10.1016/S2213-2600(14)70297-8DOI Listing
February 2015

Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice.

Am J Physiol Lung Cell Mol Physiol 2015 Jan 7;308(1):L96-103. Epub 2014 Nov 7.

Department of Molecular Pharmacology, University of Groningen, The Netherlands; GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00259.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315453PMC
January 2015

Development of a tool to recognize small airways dysfunction in asthma (SADT).

Health Qual Life Outcomes 2014 Nov 22;12:155. Epub 2014 Nov 22.

Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1186/s12955-014-0155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253607PMC
November 2014

Parametric response mapping as an indicator of bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2014 Oct 18;20(10):1592-8. Epub 2014 Jun 18.

Blood and Marrow Transplant Program, University of Michigan, Ann Arbor, Michigan; Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1016/j.bbmt.2014.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163140PMC
October 2014

Advanced glycation end products in the skin are enhanced in COPD.

Metabolism 2014 Sep 13;63(9):1149-56. Epub 2014 Jun 13.

University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.06.006DOI Listing
September 2014

Glucocorticoids induce the production of the chemoattractant CCL20 in airway epithelium.

Eur Respir J 2014 Aug 13;44(2):361-70. Epub 2014 Mar 13.

University of Groningen, University Medical Center Groningen, Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, Groningen University of Groningen, University Medical Center Groningen, GRIAC research Institute, Groningen

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http://dx.doi.org/10.1183/09031936.00209513DOI Listing
August 2014

Eosinophilic inflammation in subjects with mild-to-moderate asthma with and without obesity: disparity between sputum and biopsies.

Am J Respir Crit Care Med 2014 May;189(10):1281-4

1 University of Groningen Groningen, The Netherlands and GRIAC Research Institute Groningen, The Netherlands.

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http://dx.doi.org/10.1164/rccm.201310-1841LEDOI Listing
May 2014

Asthma and chronic obstructive pulmonary disease: similarities and differences.

Clin Chest Med 2014 Mar 12;35(1):143-56. Epub 2013 Dec 12.

University of Groningen, Department of Pulmonology, GRIAC research institute, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.ccm.2013.09.010DOI Listing
March 2014

Oxidant-induced corticosteroid unresponsiveness in human bronchial epithelial cells.

Thorax 2014 Jan 26;69(1):5-13. Epub 2013 Aug 26.

Laboratory of Allergology & Pulmonary Diseases, Department of Pathology & Medical Biology, University of Groningen, University Medical Center Groningen, , Groningen, The Netherlands.

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http://dx.doi.org/10.1136/thoraxjnl-2013-203520DOI Listing
January 2014

Quantification of free and total desmosine and isodesmosine in human urine by liquid chromatography tandem mass spectrometry: a comparison of the surrogate-analyte and the surrogate-matrix approach for quantitation.

J Chromatogr A 2014 Jan 18;1326:13-9. Epub 2013 Dec 18.

University of Groningen, Department of Pharmacy, Analytical Biochemistry, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2013.12.035DOI Listing
January 2014

Are salmeterol's beneficial effects on corticosteroid action in the airways executed at the epithelial barrier?

Respirology 2013 Nov;18(8):1165-6

Laboratory of Allergology and Pulmonary Diseases, University of Groningen, Groningen, The Netherlands; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; GRIAC Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/resp.12180DOI Listing
November 2013

Inflammation and corticosteroid responsiveness in ex-, current- and never-smoking asthmatics.

BMC Pulm Med 2013 Sep 22;13:58. Epub 2013 Sep 22.

Department of Pulmonary Diseases, University Medical Center Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.1186/1471-2466-13-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849864PMC
September 2013