Maarten E Reith

Maarten E A Reith

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Maarten E Reith

Maarten E A Reith

Publications by authors named "Maarten E A Reith"

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1PubMed Central Citations

D-578, an orally active triple monoamine reuptake inhibitor, displays antidepressant and anti-PTSD like effects in rats.

Eur J Pharmacol 2019 Nov 29;862:172632. Epub 2019 Aug 29.

Department of Psychiatry and Behavioral Neurosciences, School of Medicine, Wayne State University, USA.

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http://dx.doi.org/10.1016/j.ejphar.2019.172632DOI Listing
November 2019

Molecular Mechanisms of Amphetamines.

Handb Exp Pharmacol 2019 Jul 9. Epub 2019 Jul 9.

Department of Pharmacology, University of Michigan School of Medicine, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/164_2019_251DOI Listing
July 2019

Biased signaling agonist of dopamine D3 receptor induces receptor internalization independent of β-arrestin recruitment.

Pharmacol Res 2019 May 4;143:48-57. Epub 2019 Mar 4.

Department of Microbiology and Immunology, Drexel University College of Medicine, PA 19129, United States; Department of Pharmacology and Physiology, Drexel University College of Medicine, PA 19102, United States. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2019.03.003DOI Listing
May 2019

Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention.

Neuropharmacology 2019 04 8;148:178-188. Epub 2019 Jan 8.

Department of Microbiology and Immunology, Institute for Molecular Medicine, Drexel University College of Medicine, Philadelphia, PA, USA; Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424628PMC
April 2019

Design, Synthesis, and Pharmacological Characterization of Carbazole Based Dopamine Agonists as Potential Symptomatic and Neuroprotective Therapeutic Agents for Parkinson's Disease.

ACS Chem Neurosci 2019 01 24;10(1):396-411. Epub 2018 Oct 24.

Department of Pharmaceutical Sciences , Wayne State University , Detroit , Michigan 48202 , United States.

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http://dx.doi.org/10.1021/acschemneuro.8b00291DOI Listing
January 2019

Tamoxifen Directly Interacts with the Dopamine Transporter.

J Pharmacol Exp Ther 2018 10 14;367(1):119-128. Epub 2018 Aug 14.

Gnegy Laboratory, Department of Pharmacology, University of Michigan School of Medicine, Ann Arbor, Michigan (S.R.M., B.G., M.E.G.); and Reith Laboratory, Department of Psychiatry, University of New York School of Medicine, New York, New York (K.C.S., K.T.J., J.Z., M.E.A.R.)

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http://dx.doi.org/10.1124/jpet.118.248179DOI Listing
October 2018

Latch and trigger role for R445 in DAT transport explains molecular basis of DTDS.

Bioorg Med Chem Lett 2018 02 8;28(3):470-475. Epub 2017 Dec 8.

3D-2drug, LLC, P.O. Box 184, Fair Lawn, NJ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993566PMC
February 2018

Functional properties of dopamine transporter oligomers after copper linking.

J Neurochem 2018 01 21;144(2):162-171. Epub 2017 Dec 21.

Department of Psychiatry, New York University School of Medicine, New York City, New York, USA.

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http://dx.doi.org/10.1111/jnc.14259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760346PMC
January 2018

Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding.

J Biol Chem 2017 11 22;292(46):19066-19075. Epub 2017 Sep 22.

From the Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58201 and

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http://dx.doi.org/10.1074/jbc.M117.787002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704487PMC
November 2017

A Novel Iron(II) Preferring Dopamine Agonist Chelator as Potential Symptomatic and Neuroprotective Therapeutic Agent for Parkinson's Disease.

ACS Chem Neurosci 2017 04 27;8(4):723-730. Epub 2017 Jan 27.

Department of Pharmaceutical Sciences, Wayne State University , Detroit, Michigan 48202, United States.

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http://dx.doi.org/10.1021/acschemneuro.6b00356DOI Listing
April 2017

Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists.

ACS Chem Neurosci 2017 03 23;8(3):486-500. Epub 2016 Nov 23.

Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19102, United States.

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http://dx.doi.org/10.1021/acschemneuro.6b00221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813806PMC
March 2017

Effects of diet and insulin on dopamine transporter activity and expression in rat caudate-putamen, nucleus accumbens, and midbrain.

J Neurochem 2017 03 31;140(5):728-740. Epub 2017 Jan 31.

Department of Psychiatry, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1111/jnc.13930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475276PMC
March 2017

Novel multifunctional dopamine D/D receptors agonists with potential neuroprotection and anti-alpha synuclein protein aggregation properties.

Bioorg Med Chem 2016 11 20;24(21):5088-5102. Epub 2016 Aug 20.

Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy & Health Sciences, Wayne State University, Detroit, MI 48202, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896163062
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http://dx.doi.org/10.1016/j.bmc.2016.08.021DOI Listing
November 2016

Impact of disruption of secondary binding site S2 on dopamine transporter function.

J Neurochem 2016 09 14;138(5):694-9. Epub 2016 Jul 14.

Department of Psychiatry, New York University School of Medicine, New York City, New York, USA.

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http://dx.doi.org/10.1111/jnc.13704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996714PMC
September 2016

Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D₂ and D₃ Receptors.

Neurochem Res 2016 Feb 31;41(1-2):328-339. Epub 2015 Dec 31.

Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1007/s11064-015-1808-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775387PMC
February 2016

Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.

PLoS One 2014 26;9(11):e113420. Epub 2014 Nov 26.

New York University, Department of Psychiatry, New York, NY, United States; New York University, Department of Biochemistry and Molecular Pharmacology, New York, NY, United States.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113420PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245125PMC
July 2015

Use of radiolabeled antagonist assays for assessing agonism at D2 and D3 dopamine receptors: comparison with functional GTPγS assays.

J Neurosci Methods 2015 Jun 1;248:7-15. Epub 2015 Apr 1.

Department of Psychiatry, New York University School of Medicine, New York, NY, USA; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2015.03.028DOI Listing
June 2015

Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities.

J Neurochem 2015 Apr 26;133(2):167-73. Epub 2015 Jan 26.

Department of Psychiatry, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1111/jnc.13025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393779PMC
April 2015

Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter.

Drug Alcohol Depend 2015 Feb 18;147:1-19. Epub 2014 Dec 18.

Psychobiology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297708PMC
February 2015

Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation.

PLoS One 2013 16;8(10):e77262. Epub 2013 Oct 16.

Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America ; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077262PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818563PMC
August 2014

Multifunctional D2/D3 agonist D-520 with high in vivo efficacy: modulator of toxicity of alpha-synuclein aggregates.

ACS Chem Neurosci 2014 Aug 9;5(8):700-17. Epub 2014 Jul 9.

Department of Pharmaceutical Sciences, Wayne State University , Detroit, Michigan 48202, United States.

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http://pubs.acs.org/doi/10.1021/cn500084x
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http://dx.doi.org/10.1021/cn500084xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140597PMC
August 2014

Novel structure--function information on biogenic amine transporters revealed by site-directed mutagenesis and alkylation.

Neurochem Res 2013 Jul 27;38(7):1301-2. Epub 2013 Mar 27.

Department of Psychiatry, and Biochemistry and Molecular Pharmacology, Alexandria Center for Life Sciences, New York University School of Medicine, 450 E 29th Street, New York, NY 10016, USA.

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http://dx.doi.org/10.1007/s11064-013-1025-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702163PMC
July 2013

Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates.

J Pharmacol Exp Ther 2013 Jul 8;346(1):2-10. Epub 2013 Apr 8.

Department of Neurosurgery, New York University School of Medicine, 455 First Ave., Public Health Laboratories (8th Floor), New York, New York 10016, USA.

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http://dx.doi.org/10.1124/jpet.111.191056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684841PMC
July 2013

Importance of cholesterol in dopamine transporter function.

J Neurochem 2012 Dec 11;123(5):700-15. Epub 2012 Oct 11.

Department of Psychiatry, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1111/jnc.12007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517300PMC
December 2012

Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.

J Pharmacol Exp Ther 2012 Nov 15;343(2):413-25. Epub 2012 Aug 15.

Department of Psychiatry, New York University School of Medicine, 450 E 29th Street, Alexandria Building Room 803, New York, NY 10016, USA.

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http://dx.doi.org/10.1124/jpet.112.193771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477221PMC
November 2012

The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors.

PLoS One 2011 17;6(10):e25790. Epub 2011 Oct 17.

Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025790PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197159PMC
April 2012

Ibogaine and the inhibition of acetylcholinesterase.

J Ethnopharmacol 2012 Feb 19;139(3):879-82. Epub 2011 Dec 19.

Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03788741110087
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http://dx.doi.org/10.1016/j.jep.2011.12.006DOI Listing
February 2012

Characterization of [³H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive.

J Neurosci Methods 2012 Jan 12;203(1):19-27. Epub 2011 Sep 12.

Department of Psychiatry, New York University School of Medicine, Room MHL HN-518, 550 First Ave., New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2011.08.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221803PMC
January 2012

SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter.

J Neurochem 2011 Sep 21;118(5):714-20. Epub 2011 Jul 21.

Department of Physiology and Neuroscience, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07357.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337772PMC
September 2011

Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies.

Biochem Pharmacol 2011 Jan 15;81(1):157-63. Epub 2010 Sep 15.

Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19129, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00062952100065
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http://dx.doi.org/10.1016/j.bcp.2010.08.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991514PMC
January 2011

The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization.

Eur J Pharmacol 2010 Dec 16;648(1-3):127-32. Epub 2010 Sep 16.

Department of Pharmacology & Toxicology, Virginia Commonwealth University, 410 N. 12th Street, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1016/j.ejphar.2010.08.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953608PMC
December 2010

Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine.

J Neurochem 2010 Aug 18;114(3):873-85. Epub 2010 May 18.

Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA.

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http://doi.wiley.com/10.1111/j.1471-4159.2010.06818.x
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http://dx.doi.org/10.1111/j.1471-4159.2010.06818.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910181PMC
August 2010

Bivalent phenethylamines as novel dopamine transporter inhibitors: evidence for multiple substrate-binding sites in a single transporter.

J Neurochem 2010 Mar 12;112(6):1605-18. Epub 2010 Jan 12.

Department of Pharmacology, New York University School of Medicine, New York City, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2010.06583.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914574PMC
March 2010

Regulation of the dopamine transporter: aspects relevant to psychostimulant drugs of abuse.

Ann N Y Acad Sci 2010 Feb;1187:316-40

Department of Pharmacology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05148.xDOI Listing
February 2010

Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.

Nat Struct Mol Biol 2009 Jun 10;16(6):652-7. Epub 2009 May 10.

Kimmel Center for Biology and Medicine at the Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/nsmb.1602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758934PMC
June 2009

Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters.

J Neurochem 2009 May 11;109(4):981-94. Epub 2009 Mar 11.

Department of Psychiatry, New York University School of Medicine, Millhauser Labs, New York, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2009.06034.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696066PMC
May 2009

D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.

Eur J Pharmacol 2008 Jul 20;589(1-3):73-9. Epub 2008 May 20.

Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.ejphar.2008.05.008DOI Listing
July 2008

Substrates dissociate dopamine transporter oligomers.

J Neurochem 2008 May 18;105(3):910-20. Epub 2007 Dec 18.

Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.05195.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926875PMC
May 2008

Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors.

J Comput Aided Mol Des 2008 Jan 4;22(1):1-17. Epub 2007 Dec 4.

Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1007/s10822-007-9146-7DOI Listing
January 2008

LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.

Science 2007 Sep 9;317(5843):1390-3. Epub 2007 Aug 9.

Kimmel Center for Biology and Medicine at the Skirball Institute of Biomolecular Medicine and Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1126/science.1147614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711652PMC
September 2007

Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells.

J Neurochem 2007 Apr 22;101(2):377-88. Epub 2007 Jan 22.

Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2006.04384.xDOI Listing
April 2007

Design, synthesis, and preliminary SAR study of 3- and 6-side-chain-extended tetrahydro-pyran analogues of cis- and trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine.

Bioorg Med Chem 2006 Jun 14;14(11):3953-66. Epub 2006 Feb 14.

Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2006.01.051DOI Listing
June 2006

Chronic food restriction and dopamine transporter function in rat striatum.

Brain Res 2006 Apr 3;1082(1):98-101. Epub 2006 Mar 3.

Department of Psychiatry, Millhauser Labs, New York University, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.01.094DOI Listing
April 2006

Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates.

Neuropharmacology 2005 Nov 24;49(6):769-79. Epub 2005 Aug 24.

Department of Biological Sciences, Illinois State University, Normal, IL, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2005.07.002DOI Listing
November 2005

Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity.

J Neurosci Methods 2005 Apr;143(1):87-94

Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, Room MHL-604, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2004.09.015DOI Listing
April 2005

Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters.

Bioorg Med Chem 2004 Dec;12(23):6301-15

Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2004.07.069DOI Listing
December 2004

Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.

Eur J Pharmacol 2004 Dec;506(1):17-26

Department of Biological Sciences, Illinois State University, Normal, IL 61790, USA.

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http://dx.doi.org/10.1016/j.ejphar.2004.10.028DOI Listing
December 2004

Synthesis and biological characterization of novel hybrid 7-[[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors.

Bioorg Med Chem 2004 Aug;12(16):4361-73

Wayne State University, Department of Pharmaceutical Sciences, Applebaum College of Pharmacy and Health Science, RM# 3128, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2004.06.019DOI Listing
August 2004

The role of N-glycosylation in function and surface trafficking of the human dopamine transporter.

J Biol Chem 2004 May 15;279(20):21012-20. Epub 2004 Mar 15.

Department of Biological Sciences, Illinois State University, Normal, IL 61790, USA.

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http://dx.doi.org/10.1074/jbc.M311972200DOI Listing
May 2004

Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential.

J Neurochem 2004 May;89(3):750-65

Department of Psychiatry, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02409.xDOI Listing
May 2004

Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.

J Neurochem 2004 May;89(4):853-64

Department of Psychiatry, New York University School of Medicine, New York 10016, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02386.xDOI Listing
May 2004

Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6.

Pflugers Arch 2004 Feb 29;447(5):519-31. Epub 2003 Apr 29.

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, Illinois, USA.

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http://link.springer.com/content/pdf/10.1007/s00424-003-1064
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http://link.springer.com/10.1007/s00424-003-1064-5
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http://dx.doi.org/10.1007/s00424-003-1064-5DOI Listing
February 2004

Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.

J Biol Chem 2004 Feb 2;279(7):5508-19. Epub 2003 Dec 2.

Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1074/jbc.M306294200DOI Listing
February 2004

Structure-activity relationships for substrate recognition by the human dopamine transporter.

Biochem Pharmacol 2004 Jan;67(2):293-302

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Box 1649, Peoria, IL 61656-1649, USA.

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http://dx.doi.org/10.1016/j.bcp.2003.09.013DOI Listing
January 2004

Binding of cocaine-like radioligands to the dopamine transporter at 37 degrees C: effect of Na+ and substrates.

J Neurosci Methods 2003 Dec;131(1-2):27-33

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, PO Box 1649, Peoria, IL 61656-1649, USA.

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http://dx.doi.org/10.1016/s0165-0270(03)00230-9DOI Listing
December 2003

Substrate-induced trafficking of the dopamine transporter in heterologously expressing cells and in rat striatal synaptosomal preparations.

J Pharmacol Exp Ther 2003 Nov 15;307(2):729-36. Epub 2003 Sep 15.

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Box 1649, Peoria, IL 61656-1649, USA.

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http://dx.doi.org/10.1124/jpet.103.055095DOI Listing
November 2003

Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter.

Eur J Pharmacol 2003 Oct;478(2-3):89-95

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Box 1649, Peoria, IL 61656-1649, USA.

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http://dx.doi.org/10.1016/j.ejphar.2003.08.045DOI Listing
October 2003

Dopamine transporter as target for drug development of cocaine dependence medications.

Eur J Pharmacol 2003 Oct;479(1-3):93-106

Department of Pharmaceutical Sciences, Applebaum College of Pharmacy and Health Science, Wayne State University, 3128 Applebaun Hall, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.ejphar.2003.08.060DOI Listing
October 2003

Na+ and the substrate permeation pathway in dopamine transporters.

Eur J Pharmacol 2003 Oct;479(1-3):213-21

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Box 1649, Peoria, IL 61656-1649, USA.

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http://dx.doi.org/10.1016/j.ejphar.2003.08.070DOI Listing
October 2003

Na+ stimulates binding of dopamine to the dopamine transporter in cells but not in cell-free preparations.

J Neurochem 2003 Aug;86(3):678-86

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, Illinois 61656, USA.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01889.xDOI Listing
August 2003

Nitric oxide inhibits uptake of dopamine and N-methyl-4-phenylpyridinium (MPP+) but not release of MPP+ in rat C6 glioma cells expressing human dopamine transporter.

Br J Pharmacol 2002 Dec;137(8):1155-62

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656-1649, U.S.A.

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http://doi.wiley.com/10.1038/sj.bjp.0704974
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http://dx.doi.org/10.1038/sj.bjp.0704974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573603PMC
December 2002

Concurrent autoreceptor-mediated control of dopamine release and uptake during neurotransmission: an in vivo voltammetric study.

J Neurosci 2002 Jul;22(14):6272-81

Cellular and Integrative Physiology Section, Department of Biological Sciences, Illinois State University, Normal, Illinois 61790-4120, USA.

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http://dx.doi.org/20026630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757948PMC
July 2002

Nitric oxide scavenger carboxy-PTIO potentiates the inhibition of dopamine uptake by nitric oxide donors.

Eur J Pharmacol 2002 Jul;448(1):27-30

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656-1649, USA.

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http://dx.doi.org/10.1016/s0014-2999(02)01908-8DOI Listing
July 2002

Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.

J Neurochem 2002 Jun;81(6):1383-93

Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, Illinois 61656, USA.

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http://dx.doi.org/10.1046/j.1471-4159.2002.00941.xDOI Listing
June 2002

An analysis of the binding of cocaine analogues to the monoamine transporters using tensor decomposition 3-d QSAR.

Bioorg Med Chem 2002 May;10(5):1197-206

Department of Medicinal Chemistry & Pharmacognosy, University of Illinois at Chicago, 60612, USA.

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http://dx.doi.org/10.1016/s0968-0896(01)00389-3DOI Listing
May 2002

A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors.

Bioorg Med Chem Lett 2002 Feb;12(4):619-22

Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/s0960-894x(01)00820-4DOI Listing
February 2002