Publications by authors named "M S Qureshi"

1,280 Publications

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Investigation of 9000 hours multi-stress aging effects on High-Temperature Vulcanized Silicone Rubber with silica (nano/micro) filler hybrid composite insulator.

PLoS One 2021 28;16(7):e0253372. Epub 2021 Jul 28.

Manchester Metropolitan University, Manchester, United Kingdom.

Degradation in the polymeric insulators is caused due to the environmental stresses. The main aim of this paper is to explore the improved aging characteristics of hybrid samples by adding nano/micro silica in High Temperature Vulcanized Silicone Rubber (HTV-SiR) under long term accelerated aging conditions for 9000 hours. As HTV-SiR is unable to sustain environmental stresses for a long time, thus a long term accelerated aging behavior is an important phenomenon to be considered for field application. The aging characteristics of nano/micro filled HTV-SiR are analyzed by using techniques such as Scanning Electron Microscopy (SEM), Leakage Current (LC), Fourier Transform Infrared Microscopy (FTIR), Hydrophobicity Classification (HC), and breakdown strength for the aging time of 9000 hours. FTIR and leakage currents are measured after every cycle. All the co-filled samples revealed escalated aging characteristics as compared to the neat sample except the SN8 sample (8% nano-silica+20% micro-silica) after 9000 hours of aging. The highest loading of 6% and 8% nano-silica with 20% micro-silica do not contribute to the improved performance when compared with the neat and hybrid samples. However, from the critical experimental analysis, it is deduced that SN2 sample (2% nano-silica+20% micro-silica) is highly resistant to the long term accelerated aging conditions. SN2 has no cracks, lower loss percentages in the important FTIR absorption peaks, higher breakdown strength and superior HC after aging as compared to the unfilled and hybrid samples.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0253372PLOS
July 2021

Aflatoxin B Induced Structural and Conformational Changes in Bovine Serum Albumin: A Multispectroscopic and Circular Dichroism-Based Study.

ACS Omega 2021 Jul 8;6(28):18054-18064. Epub 2021 Jul 8.

Department of Biochemistry Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, India.

Aflatoxin B (AFB) is a mutagen that has been categorized as a group 1 human carcinogen by the International Agency for Research on Cancer. It is produced as a secondary metabolite by soil fungi and Here, in this study, the effect of AFB on the structure and conformation of bovine serum albumin (BSA) using multispectroscopic tools like fluorescence spectroscopy, ultraviolet-visible absorption spectroscopy, and circular dichroism spectropolarimetry has been ascertained. Ultraviolet absorption spectroscopy revealed hyperchromicity in the absorption spectra of BSA in the presence of AFB. The binding constant was calculated in the range of 10 M, by fluorescence spectroscopy suggesting moderate binding of the toxin to BSA. The study also confirms the static nature of fluorescence quenching. The stoichiometry of binding sites was found to be unity. The competing capability of warfarin for AFB was higher than ibuprofen as calculated from site marker displacement assay. Förster resonance energy transfer confirmed the high efficiency of energy transfer from BSA to AFB. Circular dichroism spectropolarimetry showed a decrease in the α-helix in BSA in the presence of AFB. The melting temperature of BSA underwent an increment in the presence of a mycotoxin from 62.5 to 70.3 °C. Molecular docking confirmed the binding of AFB to subdomain IIA in BSA.
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http://dx.doi.org/10.1021/acsomega.1c01799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296610PMC
July 2021

Hollow cuboidal MnCoO coupled with nickel phosphate: a promising oxygen evolution reaction electrocatalyst.

Chem Commun (Camb) 2021 Jul 22. Epub 2021 Jul 22.

Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India.

The growth of hierarchical morphologies of complex metal oxides directly on the substrate is a challenging task. Herein we report a unique hollow-cuboidal MnCo2O4 (h-MCO) morphology that offers insights into the efficient charge-transfer and surface kinetics for the oxygen evolution reaction. h-MCO coupled nickel phosphate under alkaline conditions outperforms the benchmark RuO2.
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http://dx.doi.org/10.1039/d1cc02383gDOI Listing
July 2021

Missing in Action: Reports of Interdisciplinary Integration in Canadian Palliative Care.

Curr Oncol 2021 Jul 16;28(4):2699-2707. Epub 2021 Jul 16.

Tom Baker Cancer Centre, Alberta Health Services, Calgary, AB T2N 4N2, Canada.

Palliative care has an interdisciplinary tradition and Canada is a leader in its research and practice. Yet even in Canada, a full interdisciplinary complement is often lacking, with psychosocial presence ranging from 0-67.4% depending on the discipline and region. We sought to examine the most notable gaps in care from the perspective of Canadian palliative professionals. Canadian directors of palliative care programs were surveyed with respect to interdisciplinary integration. Participants responded in writing or by phone interview. We operationalized reports of interdisciplinary professions as either "present" or "under/not-represented". The Vaismoradi, Turunen, and Bondas' procedure was used for content analysis. Our 14 participants consisted of physicians (85.7%), nurses (14.3%), and a social worker (7.1%) from Ontario (35.7%), British Columbia (14.3%), Alberta (14.3%), Quebec (14.3%), Nova Scotia (14.3%), and New Brunswick (7.1%). Psychology and social work were equally and most frequently reported as "under/not represented" (5/14, each). All participants reported the presence of medical professionals (physicians and nurses) and these groups were not reported as under/not represented. Spiritual care and others (e.g., rehabilitation and volunteers) were infrequently reported as "under/not represented". Qualitative themes included Commonly Represented Disciplines, Quality of Multidisciplinary Collaboration, Commonly Under-Represented Disciplines, and Special Concern: Psychosocial Care. Similar to previous reports, we found that (1) psychology was under-represented yet highly valued and (2) despite social work's relative high presence in care, our participants reported a higher need for more. These finding highlight those psychosocial gaps in care are most frequently noted by palliative care professionals, especially psychology and social work. We speculate on barriers and enablers to addressing this need.
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http://dx.doi.org/10.3390/curroncol28040235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293061PMC
July 2021

Reflecting on Palliative Care Integration in Canada: A Qualitative Report.

Curr Oncol 2021 Jul 19;28(4):2753-2762. Epub 2021 Jul 19.

Tom Baker Cancer Centre, Alberta Health Services, Calgary, AB T2N 4N2, Canada.

Studies have identified integrated interdisciplinary care as a hallmark of effective palliative care. Although models attempt to show how integration may function, there is little literature available that practically explores how integration is fostered and maintained. In this study we asked palliative care clinicians across Canada to comment on how services are integrated across the healthcare system. This is an analysis of qualitative data from a larger study, wherein clinicians provided written responses regarding their experiences. Content analysis was used to identify response categories. Clinicians ( = 14) included physicians, a nurse and a social worker from six provinces. They identified the benefits of formalized relationships and collaboration pathways with other services to streamline referral and consultation. Clinicians perceived a need for better training of residents and primary care physicians in the community and more acceptance, shared understanding, and referrals. Clinicians also described integrating well with oncology departments. Lastly, clinicians considered integration a complex process with departmental, provincial, and national involvement. The needs and strengths identified by the clinicians mirror the qualities of successfully integrated palliative care programs globally and highlight specific areas in policy, education, practice, and research that could benefit those in Canada.
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http://dx.doi.org/10.3390/curroncol28040240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293234PMC
July 2021
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